NL990036I2 - Bereiding en toepassing van polyanhydriden met hoog molecuulgewicht. - Google Patents

Bereiding en toepassing van polyanhydriden met hoog molecuulgewicht.

Info

Publication number
NL990036I2
NL990036I2 NL990036C NL990036C NL990036I2 NL 990036 I2 NL990036 I2 NL 990036I2 NL 990036 C NL990036 C NL 990036C NL 990036 C NL990036 C NL 990036C NL 990036 I2 NL990036 I2 NL 990036I2
Authority
NL
Netherlands
Prior art keywords
molecular weight
polyanhydrides
high molecular
preparation
application
Prior art date
Application number
NL990036C
Other languages
English (en)
Other versions
NL990036I1 (nl
Original Assignee
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology filed Critical Massachusetts Inst Technology
Publication of NL990036I1 publication Critical patent/NL990036I1/nl
Publication of NL990036I2 publication Critical patent/NL990036I2/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G67/00Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing oxygen or oxygen and carbon, not provided for in groups C08G2/00 - C08G65/00
    • C08G67/04Polyanhydrides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Polyethers (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyamides (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NL990036C 1986-08-01 1999-10-18 Bereiding en toepassing van polyanhydriden met hoog molecuulgewicht. NL990036I2 (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/892,809 US4757128A (en) 1986-08-01 1986-08-01 High molecular weight polyanhydride and preparation thereof

Publications (2)

Publication Number Publication Date
NL990036I1 NL990036I1 (nl) 1999-12-01
NL990036I2 true NL990036I2 (nl) 2001-01-02

Family

ID=25400529

Family Applications (1)

Application Number Title Priority Date Filing Date
NL990036C NL990036I2 (nl) 1986-08-01 1999-10-18 Bereiding en toepassing van polyanhydriden met hoog molecuulgewicht.

Country Status (11)

Country Link
US (1) US4757128A (nl)
EP (1) EP0260415B1 (nl)
JP (1) JP2700646B2 (nl)
KR (1) KR880002904A (nl)
AT (1) ATE145657T1 (nl)
CA (1) CA1274339A (nl)
DE (2) DE260415T1 (nl)
ES (1) ES2006417T3 (nl)
GR (2) GR880300163T1 (nl)
LU (1) LU90462I2 (nl)
NL (1) NL990036I2 (nl)

Families Citing this family (167)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5705598A (en) 1985-04-23 1998-01-06 The Boeing Company Polyester sulfone oligomers and blends
US5512676A (en) 1987-09-03 1996-04-30 The Boeing Company Extended amideimide hub for multidimensional oligomers
US5714566A (en) 1981-11-13 1998-02-03 The Boeing Company Method for making multiple chemically functional oligomers
US5516876A (en) 1983-09-27 1996-05-14 The Boeing Company Polyimide oligomers and blends
US5969079A (en) 1985-09-05 1999-10-19 The Boeing Company Oligomers with multiple chemically functional end caps
US5210213A (en) 1983-06-17 1993-05-11 The Boeing Company Dimensional, crosslinkable oligomers
US5693741A (en) 1988-03-15 1997-12-02 The Boeing Company Liquid molding compounds
US5328695A (en) * 1983-03-22 1994-07-12 Massachusetts Institute Of Technology Muscle morphogenic protein and use thereof
US4880635B1 (en) * 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
US5618907A (en) 1985-04-23 1997-04-08 The Boeing Company Thallium catalyzed multidimensional ester oligomers
US4789724A (en) * 1986-10-17 1988-12-06 Massachusetts Institute Of Technology Preparation of anhydride copolymers
US6309635B1 (en) 1986-11-20 2001-10-30 Children's Medical Center Corp. Seeding parenchymal cells into compression resistant porous scaffold after vascularizing in vivo
US5567612A (en) * 1986-11-20 1996-10-22 Massachusetts Institute Of Technology Genitourinary cell-matrix structure for implantation into a human and a method of making
US5759830A (en) * 1986-11-20 1998-06-02 Massachusetts Institute Of Technology Three-dimensional fibrous scaffold containing attached cells for producing vascularized tissue in vivo
US4933431A (en) * 1987-07-31 1990-06-12 Massachusetts Institute Of Technology One step preparation of poly(amide-anhydride)
US4857311A (en) * 1987-07-31 1989-08-15 Massachusetts Institute Of Technology Polyanhydrides with improved hydrolytic degradation properties
US5817744A (en) 1988-03-14 1998-10-06 The Boeing Company Phenylethynyl capped imides
US4990336A (en) * 1989-02-08 1991-02-05 Biosearch, Inc. Sustained release dosage form
US5356630A (en) * 1989-02-22 1994-10-18 Massachusetts Institute Of Technology Delivery system for controlled release of bioactive factors
US4999417A (en) * 1989-03-30 1991-03-12 Nova Pharmaceutical Corporation Biodegradable polymer compositions
US4997904A (en) * 1989-08-25 1991-03-05 Nova Pharmaceutical Corporation Aromatic polyanhydride compositions
US5001215A (en) * 1989-11-02 1991-03-19 Hoechst Celanese Corp. Aromatic polyester from 1,3-bis(p-carboxyphenoxy)propane
AU655762B2 (en) * 1989-12-26 1995-01-12 Nova Pharmaceutical Corporation Prodrug anhydrides of asprin, indomethacin and ibuprofen, their preparation, compositions, and anti-inflammatory method of use
US5175235A (en) * 1990-06-04 1992-12-29 Nova Pharmaceutical Corporation Branched polyanhydrides
US5240963A (en) * 1990-01-19 1993-08-31 Nova Pharmaceutical Corporation Branched polyanhydrides
US5179189A (en) * 1990-01-19 1993-01-12 Nova Pharmaceutical Corporation Fatty acid terminated polyanhydrides
US5171812A (en) * 1990-01-19 1992-12-15 Nova Pharmaceutical Corporation Polyanhydrides of oligomerized unsaturated aliphatic acids
US5270419A (en) * 1990-01-19 1993-12-14 Nova Pharmaceutical Corporation Polyanhydrides of oligomerized unsaturated aliphatic acids
US5317079A (en) * 1990-01-19 1994-05-31 Nova Pharmaceutical Corporation Fatty acid terminated polyanhydride
US5126147A (en) * 1990-02-08 1992-06-30 Biosearch, Inc. Sustained release dosage form
EP0568651B1 (en) * 1991-02-01 2002-04-17 Massachusetts Institute Of Technology Biodegradable polymer blends for drug delivery
US5330768A (en) * 1991-07-05 1994-07-19 Massachusetts Institute Of Technology Controlled drug delivery using polymer/pluronic blends
ES2038072B1 (es) * 1991-07-12 1994-02-16 Univ Valladolid Procedimiento para la obtencion de polianhidridos a base de acidos dicarboxilicos y anhidrido acetico.
WO1993007913A1 (en) * 1991-10-24 1993-04-29 Children's Medical Center Corporation Neomorphogenesis of urological structures in vivo from cell culture
WO1993011188A1 (fr) * 1991-11-26 1993-06-10 Kansai Paint Company, Limited Agent de reticulation et composition durcissable par cuisson
US5518730A (en) 1992-06-03 1996-05-21 Fuisz Technologies Ltd. Biodegradable controlled release flash flow melt-spun delivery system
US5264540A (en) * 1992-07-20 1993-11-23 Ethicon, Inc. Aromatic polyanhydrides
PT659073E (pt) * 1992-09-10 2002-06-28 Childrens Medical Center Matrizes polimericas biodegradaveis para entrega sustentada de agentes anestesicos locais
US5700485A (en) * 1992-09-10 1997-12-23 Children's Medical Center Corporation Prolonged nerve blockade by the combination of local anesthetic and glucocorticoid
US5922340A (en) 1992-09-10 1999-07-13 Children's Medical Center Corporation High load formulations and methods for providing prolonged local anesthesia
US5709854A (en) * 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
US5321113A (en) * 1993-05-14 1994-06-14 Ethicon, Inc. Copolymers of an aromatic anhydride and aliphatic ester
US5543158A (en) * 1993-07-23 1996-08-06 Massachusetts Institute Of Technology Biodegradable injectable nanoparticles
US5473103A (en) * 1993-12-16 1995-12-05 Yissum Research Development Co. Of The Hebrew University Of Jerusalem Biopolymers derived from hydrolyzable diacid fats
US6007845A (en) * 1994-07-22 1999-12-28 Massachusetts Institute Of Technology Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers
US5626862A (en) 1994-08-02 1997-05-06 Massachusetts Institute Of Technology Controlled local delivery of chemotherapeutic agents for treating solid tumors
US5716404A (en) * 1994-12-16 1998-02-10 Massachusetts Institute Of Technology Breast tissue engineering
US6123727A (en) * 1995-05-01 2000-09-26 Massachusetts Institute Of Technology Tissue engineered tendons and ligaments
US5855610A (en) 1995-05-19 1999-01-05 Children's Medical Center Corporation Engineering of strong, pliable tissues
US5741685A (en) * 1995-06-07 1998-04-21 Children's Medical Center Corporation Parenchymal cells packaged in immunoprotective tissue for implantation
US6129761A (en) * 1995-06-07 2000-10-10 Reprogenesis, Inc. Injectable hydrogel compositions
US5942241A (en) 1995-06-09 1999-08-24 Euro-Celtique, S.A. Formulations and methods for providing prolonged local anesthesia
US6143211A (en) * 1995-07-21 2000-11-07 Brown University Foundation Process for preparing microparticles through phase inversion phenomena
DE69636626T2 (de) * 1995-07-28 2007-08-30 Genzyme Corp., Cambridge Biologische abbaubare multiblokhydrogene und ihre verwendung wie trägerstoffe fur kontrollierte freisetzung pharmakologisch activen werstoffe und gewebekontaktmaterialen
US5968543A (en) * 1996-01-05 1999-10-19 Advanced Polymer Systems, Inc. Polymers with controlled physical state and bioerodibility
US5756652A (en) * 1996-02-29 1998-05-26 Depuy Orthopaedics, Inc. Poly (ester-anhydrides) and intermediates therefor
DE69729088T2 (de) * 1996-03-05 2005-05-12 Acusphere, Inc., Cambridge Mikroverkapselte fluorierte gase zur anwendung als bilderzeugende mittel
US5611344A (en) * 1996-03-05 1997-03-18 Acusphere, Inc. Microencapsulated fluorinated gases for use as imaging agents
US5747060A (en) * 1996-03-26 1998-05-05 Euro-Celtique, S.A. Prolonged local anesthesia with colchicine
US6299905B1 (en) 1996-04-16 2001-10-09 Depuy Orthopaedics, Inc. Bioerodable polymeric adhesives for tissue repair
US5668288A (en) * 1996-04-16 1997-09-16 Depuy Orthopaedics, Inc. Polyester ionomers for implant fabrication
US5905134A (en) * 1996-04-17 1999-05-18 Abbott Laboratories Process for the preparation of polyanhydrides
CA2260750C (en) 1996-06-24 2004-11-09 Euro-Celtique, S.A. Methods for providing safe local anesthesia
US20030077317A1 (en) * 1996-06-25 2003-04-24 Brown University Research Foundation Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients
US5955096A (en) * 1996-06-25 1999-09-21 Brown University Research Foundation Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients
US5837221A (en) * 1996-07-29 1998-11-17 Acusphere, Inc. Polymer-lipid microencapsulated gases for use as imaging agents
US6046187A (en) 1996-09-16 2000-04-04 Children's Medical Center Corporation Formulations and methods for providing prolonged local anesthesia
KR20010006026A (ko) 1997-04-03 2001-01-15 존스 홉킨스 유니버시티 스쿨 오브 메디슨 생물분해성 테레프탈레이트 폴리에스테르-폴리(포스페이트) 중합체, 조성물, 약품 및 그의 제조방법과 이용방법
US6248345B1 (en) 1997-07-02 2001-06-19 Euro-Celtique, S.A. Prolonged anesthesia in joints and body spaces
US6123956A (en) * 1997-07-10 2000-09-26 Keith Baker Methods for universally distributing therapeutic agents to the brain
US6635642B1 (en) 1997-09-03 2003-10-21 Guilford Pharmaceuticals Inc. PARP inhibitors, pharmaceutical compositions comprising same, and methods of using same
US6514983B1 (en) 1997-09-03 2003-02-04 Guilford Pharmaceuticals Inc. Compounds, methods and pharmaceutical compositions for treating neural or cardiovascular tissue damage
US6291425B1 (en) 1999-09-01 2001-09-18 Guilford Pharmaceuticals Inc. Compounds, methods and pharmaceutical compositions for treating cellular damage, such as neural or cardiovascular tissue damage
US6197785B1 (en) 1997-09-03 2001-03-06 Guilford Pharmaceuticals Inc. Alkoxy-substituted compounds, methods, and compositions for inhibiting PARP activity
US6426415B1 (en) 1997-09-03 2002-07-30 Guilford Pharmaceuticals Inc. Alkoxy-substituted compounds, methods and compositions for inhibiting parp activity
US6346536B1 (en) 1997-09-03 2002-02-12 Guilford Pharmaceuticals Inc. Poly(ADP-ribose) polymerase inhibitors and method for treating neural or cardiovascular tissue damage using the same
US7122615B1 (en) * 1998-09-10 2006-10-17 Rutgers, The State University Of New Jersey Polyanhydrides with therapeutically useful degradation products
US6486214B1 (en) * 1997-09-10 2002-11-26 Rutgers, The State University Of New Jersey Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby
PT1032605E (pt) * 1997-09-10 2007-12-12 Univ Rutgers Polianidridos com produtos de degradação terapeuticamente úteis
US6468519B1 (en) * 1997-09-10 2002-10-22 Rutgers, The State University Of New Jersey Polyanhydrides with biologically active degradation products
US6395749B1 (en) 1998-05-15 2002-05-28 Guilford Pharmaceuticals Inc. Carboxamide compounds, methods, and compositions for inhibiting PARP activity
US6419709B1 (en) 1998-10-02 2002-07-16 Guilford Pharmaceuticals, Inc. Biodegradable terephthalate polyester-poly(Phosphite) compositions, articles, and methods of using the same
US6153212A (en) * 1998-10-02 2000-11-28 Guilford Pharmaceuticals Inc. Biodegradable terephthalate polyester-poly (phosphonate) compositions, articles, and methods of using the same
US6387902B1 (en) 1998-12-31 2002-05-14 Guilford Pharmaceuticals, Inc. Phenazine compounds, methods and pharmaceutical compositions for inhibiting PARP
US6350464B1 (en) * 1999-01-11 2002-02-26 Guilford Pharmaceuticals, Inc. Methods for treating ovarian cancer, poly (phosphoester) compositions, and biodegradable articles for same
US6537585B1 (en) 1999-03-26 2003-03-25 Guilford Pharmaceuticals, Inc. Methods and compositions for treating solid tumors
US6294643B1 (en) 1999-04-20 2001-09-25 Sumitomo Chemical Co., Ltd. Aromatic polyester and molded article using the same
US6503528B1 (en) 1999-11-19 2003-01-07 Abbott Laboratories Polymeric compositions and a method of making the same
US6685928B2 (en) 1999-12-07 2004-02-03 Rutgers, The State University Of New Jersey Therapeutic compositions and methods
US20040038948A1 (en) * 1999-12-07 2004-02-26 Uhrich Kathryn E. Therapeutic compositions and methods
ATE444086T1 (de) 1999-12-07 2009-10-15 Univ Rutgers Therapeutische zusammensetzungen und verfahren zur behandlung von periodontitis mit entzündunshemmenden mitteln
US7029700B2 (en) * 2000-01-14 2006-04-18 Brown University Research Foundation Micronized freeze-dried particles
WO2001090077A1 (en) 2000-05-19 2001-11-29 Guilford Pharmaceuticals, Inc. Sulfonamide and carbamide derivatives of 6(5h)phenanthridinones and their uses
US6348475B1 (en) 2000-06-01 2002-02-19 Guilford Pharmaceuticals Inc. Methods, compounds and compositions for treating gout
AU2001279064A1 (en) * 2000-07-27 2002-02-13 Rutgers, The State University Therapeutic azo-compounds for drug delivery
AU2001278055A1 (en) * 2000-07-27 2002-02-13 Rutgers, The State University Therapeutic polyesters and polyamides
EP1363602A4 (en) * 2001-01-25 2006-01-11 Euro Celtique Sa LOCAL ANESTHESIA, AND METHOD OF USE
US20020142304A1 (en) * 2001-03-09 2002-10-03 Anderson Daniel G. Uses and methods of making microarrays of polymeric biomaterials
CA2440394C (en) * 2001-05-07 2011-10-04 Cornell Research Foundation, Inc. Biodegradable copolymers linked to segment with a plurality of functional groups
WO2003000237A2 (en) * 2001-06-22 2003-01-03 Johns Hopkins University School Of Medicine Biodegradable polymer coompositions
EP1423175B1 (en) 2001-08-08 2013-10-02 Brown University Research Foundation Methods for micronization of hydrophobic drugs
EP1478229B1 (en) 2001-11-23 2009-03-11 Rutgers, The State University Improved synthesis of polyanhyrides
US6993846B2 (en) * 2002-05-08 2006-02-07 Eveready Battery Company, Inc. Lubricating strip
AU2003251992A1 (en) * 2002-07-17 2004-02-02 Rutgers, The State University Therapeutic devices for patterned cell growth
CN100366249C (zh) * 2002-09-29 2008-02-06 天津帝士力投资控股集团有限公司 一种替莫唑胺控释给药系统
WO2004098570A1 (en) * 2002-10-30 2004-11-18 Spherics, Inc. Nanoparticulate bioactive agents
US20070218139A1 (en) * 2002-12-20 2007-09-20 Smith Thomas J High Pressure Compaction For Pharmaceutical Formulations
US20040197301A1 (en) * 2003-02-18 2004-10-07 Zhong Zhao Hybrid polymers and methods of making the same
US7662864B2 (en) * 2003-06-04 2010-02-16 Rutgers, The State University Of New Jersey Solution polymerization processes to prepare a polymer that degrades to release a physiologically active agent
CA2549195A1 (en) * 2003-12-09 2005-06-23 Spherics, Inc. Bioadhesive polymers with catechol functionality
US8957034B2 (en) * 2004-01-28 2015-02-17 Johns Hopkins University Drugs and gene carrier particles that rapidly move through mucous barriers
US8012457B2 (en) 2004-06-04 2011-09-06 Acusphere, Inc. Ultrasound contrast agent dosage formulation
WO2006026504A2 (en) * 2004-08-27 2006-03-09 Spherics, Inc. Mucoadhesive oral formulations of high permeability, high solubility drugs
US20060045865A1 (en) * 2004-08-27 2006-03-02 Spherics, Inc. Controlled regional oral delivery
CA2591586A1 (en) 2005-05-05 2006-11-09 Antisense Pharma Gmbh Dosage of oligonucleotides
US20090317376A1 (en) 2005-06-06 2009-12-24 Georgetown University Medical School Compositions And Methods For Lipo Modeling
US20070225472A1 (en) * 2006-03-23 2007-09-27 Varshney Sunil K Polyanhydride polymers and their uses in biomedical devices
US8361453B2 (en) * 2006-06-06 2013-01-29 Rutgers, The State University Of New Jersey Iodinated polymers
CA2672147A1 (en) * 2006-07-27 2008-01-31 University Of Virginia Patent Foundation System and method for intracranial implantation of therapeutic or diagnostic agents
WO2008027557A2 (en) * 2006-08-31 2008-03-06 Spherics, Inc. Topiramate compositions and methods of enhancing its bioavailability
US20100215580A1 (en) * 2006-09-08 2010-08-26 The Johns Hopkins University Compositions and methods for enhancing transport through mucus
EP2102144A4 (en) 2006-09-13 2011-03-23 Univ Rutgers ACTIVE SUBSTANCES AND THEIR OLIGOMERS AND POLYMERS
WO2008051565A2 (en) * 2006-10-23 2008-05-02 Bioabsorbable Therapeutics, Inc. A drug-release composition having a therapeutic carrier
JP5489719B2 (ja) * 2006-11-17 2014-05-14 スパーナス ファーマシューティカルズ インコーポレイテッド トピラマートの徐放性配合物
US10092524B2 (en) 2008-06-11 2018-10-09 Edge Therapeutics, Inc. Compositions and their use to treat complications of aneurysmal subarachnoid hemorrhage
US8637593B2 (en) 2008-01-09 2014-01-28 Hitachi Chemical Company, Ltd. Thermosetting resin composition, epoxy resin molding material, and polyvalent carboxylic acid condensate
WO2009088059A1 (ja) 2008-01-09 2009-07-16 Hitachi Chemical Company, Ltd. 熱硬化性樹脂組成物、エポキシ樹脂成形材料及び多価カルボン酸縮合体
WO2011006073A1 (en) 2009-07-10 2011-01-13 President And Fellows Of Harvard College Permanently charged sodium and calcium channel blockers as anti-inflammatory agents
US10058837B2 (en) 2009-08-28 2018-08-28 The Trustees Of Columbia University In The City Of New York Systems, methods, and devices for production of gas-filled microbubbles
WO2011075557A1 (en) 2009-12-16 2011-06-23 The Trustees Of Columbia University In The City Of New York Methods, devices, and systems for on-demand ultrasound-triggered drug delivery
CN106913874A (zh) * 2010-02-22 2017-07-04 优势医疗公司 治疗脑的出血性病状的方法和组合物
US8673359B2 (en) 2010-07-08 2014-03-18 Brown University Nanoparticle compositions and methods for improved oral delivery of active agents
US8741317B2 (en) 2010-08-19 2014-06-03 Rutgers, The State University Of New Jersey Slow-degrading polymers comprising salicylic acid for undelayed and sustained drug delivery
CN105997890A (zh) 2011-02-11 2016-10-12 优势医疗公司 用于改善患有蛛网膜下腔出血的人的预后的组合物和方法
AU2012240131B2 (en) 2011-04-05 2017-07-20 Edge Therapeutics Intraventricular drug delivery system for improving outcome after a brain injury affecting cerebral blood flow
CN104394891B (zh) 2012-03-16 2019-04-16 约翰霍普金斯大学 用于递送活性剂的非线性多嵌段共聚物-药物结合物
CA2867381C (en) 2012-03-16 2016-09-20 The Johns Hopkins University Controlled release formulations for the delivery of hif-1 inhibitors
CA2871778C (en) 2012-05-03 2022-09-13 Kala Pharmaceuticals, Inc. Pharmaceutical nanoparticles showing improved mucosal transport
US9827191B2 (en) 2012-05-03 2017-11-28 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
US11596599B2 (en) 2012-05-03 2023-03-07 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
KR102154880B1 (ko) 2012-05-03 2020-09-10 칼라 파마슈티컬스, 인크. 개선된 점막 수송을 나타내는 제약 나노입자
US9399019B2 (en) 2012-05-09 2016-07-26 Evonik Corporation Polymorph compositions, methods of making, and uses thereof
US9144579B2 (en) 2012-08-17 2015-09-29 Rutgers, The State University Of New Jersey Polyesters and methods of use thereof
US20140120057A1 (en) 2012-10-25 2014-05-01 Rutgers, The State University Of New Jersey Polymers and methods thereof for wound healing
US9387250B2 (en) 2013-03-15 2016-07-12 Rutgers, The State University Of New Jersey Therapeutic compositions for bone repair
WO2014153541A1 (en) 2013-03-21 2014-09-25 Eupraxia Pharmaceuticals USA LLC Injectable sustained release composition and method of using the same for treating inflammation in joints and pain associated therewith
US9862672B2 (en) 2013-05-29 2018-01-09 Rutgers, The State University Of New Jersey Antioxidant-based poly(anhydride-esters)
WO2015058868A1 (en) 2013-10-25 2015-04-30 Pangaea Biotech, S.L. Compositions and methods for the treatment of cancer
US10023521B2 (en) 2014-06-13 2018-07-17 Rutgers, The State University Of New Jersey Process and intermediates for preparing poly(anhydride-esters)
EP3193827A1 (en) 2014-08-13 2017-07-26 The Johns Hopkins University Glucocorticoid-loaded nanoparticles for prevention of corneal allograft rejection and neovascularization
US20180008718A1 (en) 2015-01-20 2018-01-11 The Johns Hopkins University Compositions for the sustained release of anti-glaucoma agents to control intraocular pressure
JP6930918B6 (ja) 2015-04-10 2021-12-15 ラトガーズ, ザ ステイト ユニバーシティ オブ ニュー ジャージー コウジ酸ポリマー
US11021443B2 (en) 2015-08-03 2021-06-01 President And Fellows Of Harvard College Charged ion channel blockers and methods for use
WO2017044789A1 (en) 2015-09-09 2017-03-16 Micell Technologies, Inc. Biopharma application of micell technology
EP3206672B1 (en) 2015-10-27 2018-03-14 Eupraxia Pharmaceuticals Inc. Sustained release formulations of local anesthetics
EP3246050A1 (de) 2016-05-17 2017-11-22 BSN medical GmbH Wund- oder hautauflage
US10449269B2 (en) 2016-08-29 2019-10-22 Yale University Particle conjugated prosthetic patches and methods of making and using thereof
WO2020028907A1 (en) 2018-08-03 2020-02-06 Brown University Compositions and methods for improving the bioavailability of glp1 and analogues thereof
MA55320A (fr) 2019-03-11 2022-01-19 Nocion Therapeutics Inc Bloqueurs de canaux ioniques substitués par un ester et méthodes d'utilisation
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10828287B2 (en) 2019-03-11 2020-11-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
JP2022525856A (ja) 2019-03-11 2022-05-20 ノシオン セラピューティクス,インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法
US11377422B2 (en) 2019-03-11 2022-07-05 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
EP4054586A4 (en) 2019-11-06 2023-11-22 Nocion Therapeutics, Inc. CHARGED ION CHANNEL BLOCKERS AND METHODS OF USE
CA3155586A1 (en) 2019-11-06 2021-05-14 Bridget M. Cole Charged ion channel blockers and methods for use
CN115279731A (zh) 2020-03-11 2022-11-01 诺西恩医疗公司 带电的离子通道阻滞剂及其使用方法
WO2024011218A1 (en) 2022-07-08 2024-01-11 Brown University Polymeric nanoparticles for long acting delivery of a peptide and methods of making and using thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2071250A (en) * 1931-07-03 1937-02-16 Du Pont Linear condensation polymers
US2071251A (en) * 1931-07-03 1937-02-16 Du Pont Fiber and method of producing it
GB968715A (en) * 1961-10-12 1964-09-02 Ici Ltd Polymeric anhydrides
US3526612A (en) * 1969-04-16 1970-09-01 Marathon Oil Co Polyanhydrides,and processes for their production
US3993071A (en) * 1971-09-09 1976-11-23 Alza Corporation Bioerodible ocular device
US3960150A (en) * 1971-09-09 1976-06-01 Alza Corporation Bioerodible ocular device
US3981303A (en) * 1971-09-09 1976-09-21 Alza Corporation Bioerodible ocular device
US3986510A (en) * 1971-09-09 1976-10-19 Alza Corporation Bioerodible ocular device
JPS60141725A (ja) * 1983-12-29 1985-07-26 Okamura Seiyu Kk ポリ酸ポリ無水物粉体
CH671402A5 (nl) * 1985-10-02 1989-08-31 Sandoz Ag

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DE3751964T2 (de) 1997-06-05
US4757128A (en) 1988-07-12
CA1274339A (en) 1990-09-18
LU90462I2 (fr) 2000-01-03
EP0260415B1 (en) 1996-11-27
JPS63258924A (ja) 1988-10-26
ES2006417T3 (es) 1997-07-01
GR3022577T3 (en) 1997-05-31
DE3751964D1 (de) 1997-01-09
EP0260415A2 (en) 1988-03-23
ES2006417A4 (es) 1989-05-01
ATE145657T1 (de) 1996-12-15
GR880300163T1 (en) 1989-01-31
KR880002904A (ko) 1988-05-12
NL990036I1 (nl) 1999-12-01
DE260415T1 (de) 1989-02-16
JP2700646B2 (ja) 1998-01-21
EP0260415A3 (en) 1988-05-18

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