NL9400096A - Nieuwe Streptomyces-stam en werkwijze voor het bereiden van antitumormiddelen daarmee. - Google Patents

Nieuwe Streptomyces-stam en werkwijze voor het bereiden van antitumormiddelen daarmee. Download PDF

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Publication number
NL9400096A
NL9400096A NL9400096A NL9400096A NL9400096A NL 9400096 A NL9400096 A NL 9400096A NL 9400096 A NL9400096 A NL 9400096A NL 9400096 A NL9400096 A NL 9400096A NL 9400096 A NL9400096 A NL 9400096A
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NL
Netherlands
Prior art keywords
aclacinomycin
culture medium
medium
aclacinomycins
cells
Prior art date
Application number
NL9400096A
Other languages
English (en)
Dutch (nl)
Original Assignee
Dongkook Pharmaceutical Co
Ki Beom Kwon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dongkook Pharmaceutical Co, Ki Beom Kwon filed Critical Dongkook Pharmaceutical Co
Publication of NL9400096A publication Critical patent/NL9400096A/nl

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P15/00Preparation of compounds containing at least three condensed carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/06Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/56Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces
    • C12R2001/56Streptomyces lavendulae
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/886Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
NL9400096A 1993-09-03 1994-01-20 Nieuwe Streptomyces-stam en werkwijze voor het bereiden van antitumormiddelen daarmee. NL9400096A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR930017589 1993-09-03
KR1019930017589A KR970000591B1 (ko) 1993-09-03 1993-09-03 신균주 스트렙토마이세스 라벤도폴리아 DKRS 및 이를 이용한 아클라시노마이신 A, B, Y 및 아글리콘(Aglycone)의 제조방법

Publications (1)

Publication Number Publication Date
NL9400096A true NL9400096A (nl) 1995-04-03

Family

ID=19362801

Family Applications (1)

Application Number Title Priority Date Filing Date
NL9400096A NL9400096A (nl) 1993-09-03 1994-01-20 Nieuwe Streptomyces-stam en werkwijze voor het bereiden van antitumormiddelen daarmee.

Country Status (13)

Country Link
US (2) US5468637A (zh)
JP (1) JP2718002B2 (zh)
KR (1) KR970000591B1 (zh)
CN (2) CN1104682A (zh)
CA (1) CA2113871C (zh)
CH (1) CH688151A5 (zh)
DE (1) DE4401546C2 (zh)
ES (1) ES2078875B1 (zh)
FR (1) FR2709497B1 (zh)
GB (1) GB2281563B (zh)
IT (1) IT1273049B (zh)
NL (1) NL9400096A (zh)
TW (1) TW258754B (zh)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4071411A (en) * 1974-07-27 1978-01-31 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Antitumor antibiotics aclacinomycins A and B [RD-9187A]
JPS5134915B2 (zh) * 1974-07-27 1976-09-29
US4204038A (en) * 1976-04-07 1980-05-20 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Process for preparing antibiotics MA 144-M1 and MA 144-M2
US4209588A (en) * 1976-10-05 1980-06-24 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Process for producing new antitumor anthracycline antibiotics
NL176004C (nl) * 1976-10-05 1985-02-01 Microbial Chem Res Found Werkwijze ter bereiding van geneesmiddelen met antitumorwerking op basis van anthracycline glycosiden en werkwijze ter bereiding van daartoe dienende anthracycline glycosiden.
JPS5648893A (en) * 1979-09-07 1981-05-02 Sanraku Inc Preparation of anthracycline glycoside
DE3164574D1 (en) * 1980-10-27 1984-08-09 Hoffmann La Roche Process for aclacinomycins and microorganism used therein
ATE11142T1 (de) * 1980-10-27 1985-01-15 F. Hoffmann-La Roche & Co. Aktiengesellschaft Herstellung von anthracyclinglycosiden.
US4405713A (en) * 1981-12-28 1983-09-20 Hoffmann-La Roche Inc. Process for the preparation of optically active anthracycline glycosides A and B
US4471052A (en) * 1982-01-18 1984-09-11 Adria Laboratories, Inc. Biosynthesis of simplified anthracyclines
SU1069433A1 (ru) * 1982-06-29 1984-11-23 Всесоюзный научно-исследовательский институт антибиотиков Штамм @ @ 12/3а-продуцент аклациномицинов @ и @

Also Published As

Publication number Publication date
DE4401546A1 (de) 1995-03-30
GB2281563A (en) 1995-03-08
JPH0775575A (ja) 1995-03-20
FR2709497A1 (fr) 1995-03-10
KR950008679A (ko) 1995-04-19
TW258754B (zh) 1995-10-01
US5468637A (en) 1995-11-21
GB2281563B (en) 1998-01-28
IT1273049B (it) 1997-07-01
CN1104682A (zh) 1995-07-05
CH688151A5 (fr) 1997-05-30
CN1108694A (zh) 1995-07-05
FR2709497B1 (fr) 1996-11-15
DE4401546C2 (de) 1997-09-25
ES2078875B1 (es) 1996-08-16
GB9400513D0 (en) 1994-03-09
ITMI940035A0 (it) 1994-01-14
JP2718002B2 (ja) 1998-02-25
US5484712A (en) 1996-01-16
ITMI940035A1 (it) 1995-07-14
KR970000591B1 (ko) 1997-01-14
ES2078875A1 (es) 1995-12-16
CA2113871A1 (en) 1995-03-04
CA2113871C (en) 2000-01-18

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BM The application is based on a (several) micro-organism(s)
BN A decision not to publish the application has become irrevocable