NL8600731A - Verbeterde gesproeidroogde lactose en werkwijze ter bereiding ervan. - Google Patents
Verbeterde gesproeidroogde lactose en werkwijze ter bereiding ervan. Download PDFInfo
- Publication number
- NL8600731A NL8600731A NL8600731A NL8600731A NL8600731A NL 8600731 A NL8600731 A NL 8600731A NL 8600731 A NL8600731 A NL 8600731A NL 8600731 A NL8600731 A NL 8600731A NL 8600731 A NL8600731 A NL 8600731A
- Authority
- NL
- Netherlands
- Prior art keywords
- lactose
- spray
- crystalline
- dried
- suspension
- Prior art date
Links
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 title claims description 60
- 239000008101 lactose Substances 0.000 title claims description 60
- 238000000034 method Methods 0.000 title description 5
- 238000002360 preparation method Methods 0.000 title description 5
- 239000013078 crystal Substances 0.000 claims description 26
- 239000000725 suspension Substances 0.000 claims description 18
- 239000002245 particle Substances 0.000 claims description 14
- 239000007921 spray Substances 0.000 claims description 13
- 238000002425 crystallisation Methods 0.000 claims description 6
- 230000008025 crystallization Effects 0.000 claims description 6
- 150000002597 lactoses Chemical class 0.000 claims description 6
- 238000001694 spray drying Methods 0.000 claims description 6
- 238000001035 drying Methods 0.000 claims description 5
- WSVLPVUVIUVCRA-KPKNDVKVSA-N Alpha-lactose monohydrate Chemical compound O.O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O WSVLPVUVIUVCRA-KPKNDVKVSA-N 0.000 claims description 3
- 239000002178 crystalline material Substances 0.000 claims description 3
- 238000004090 dissolution Methods 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 239000000126 substance Substances 0.000 description 3
- GUBGYTABKSRVRQ-DCSYEGIMSA-N Beta-Lactose Chemical compound OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-DCSYEGIMSA-N 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 230000002349 favourable effect Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000007873 sieving Methods 0.000 description 2
- 239000012798 spherical particle Substances 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- 229930195724 β-lactose Natural products 0.000 description 2
- BHKKSKOHRFHHIN-MRVPVSSYSA-N 1-[[2-[(1R)-1-aminoethyl]-4-chlorophenyl]methyl]-2-sulfanylidene-5H-pyrrolo[3,2-d]pyrimidin-4-one Chemical compound N[C@H](C)C1=C(CN2C(NC(C3=C2C=CN3)=O)=S)C=CC(=C1)Cl BHKKSKOHRFHHIN-MRVPVSSYSA-N 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 239000002054 inoculum Substances 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 239000012452 mother liquor Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000011164 primary particle Substances 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C13—SUGAR INDUSTRY
- C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
- C13K5/00—Lactose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL8600731A NL8600731A (nl) | 1986-03-21 | 1986-03-21 | Verbeterde gesproeidroogde lactose en werkwijze ter bereiding ervan. |
| US07/027,424 US4802926A (en) | 1986-03-21 | 1987-03-18 | Spray dried lactose and process for preparing the same |
| JP62065526A JPS62265295A (ja) | 1986-03-21 | 1987-03-19 | 噴霧乾燥ラクト−ス製品ならびにその製法 |
| EP87200524A EP0239172B1 (de) | 1986-03-21 | 1987-03-20 | Verbesserte sprühgetrocknete Lactose und Verfahren zu deren Herstellung |
| DE8787200524T DE3784260T2 (de) | 1986-03-21 | 1987-03-20 | Verbesserte spruehgetrocknete lactose und verfahren zu deren herstellung. |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL8600731A NL8600731A (nl) | 1986-03-21 | 1986-03-21 | Verbeterde gesproeidroogde lactose en werkwijze ter bereiding ervan. |
| NL8600731 | 1986-03-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL8600731A true NL8600731A (nl) | 1987-10-16 |
Family
ID=19847754
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL8600731A NL8600731A (nl) | 1986-03-21 | 1986-03-21 | Verbeterde gesproeidroogde lactose en werkwijze ter bereiding ervan. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4802926A (de) |
| EP (1) | EP0239172B1 (de) |
| JP (1) | JPS62265295A (de) |
| DE (1) | DE3784260T2 (de) |
| NL (1) | NL8600731A (de) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12214082B1 (en) | 2024-05-13 | 2025-02-04 | Leprino Foods Company | One pass spray dried lactose |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0778126B2 (ja) * | 1992-02-10 | 1995-08-23 | 日清紡績株式会社 | 多糖類真球状粒子及び製造方法 |
| AU2001279771A1 (en) * | 2000-07-20 | 2002-02-05 | Campina B.V. | Carrier material for dry powder inhalation |
| DE60130657T2 (de) | 2000-07-20 | 2008-07-03 | Campina Nederland Holding B.V. | Methode zur herstellung eines kristallinen tablettierungshilfstoffes, der so erhaltene hilfsstoff und seine verwendung |
| US6548099B1 (en) * | 2000-11-28 | 2003-04-15 | Hershey Foods Corporation | Process for crystallizing amorphous lactose in milk powder |
| US8992980B2 (en) | 2002-10-25 | 2015-03-31 | Boehringer Ingelheim Vetmedica Gmbh | Water-soluble meloxicam granules |
| EP1568369A1 (de) | 2004-02-23 | 2005-08-31 | Boehringer Ingelheim Vetmedica Gmbh | Verwendung von Meloxicam zur Behandlung von Atemwegserkrankungen bei Schweinen |
| RU2007133547A (ru) | 2005-02-10 | 2009-03-20 | Глаксо Груп Лимитед (GB) | Способы получения лактозы с использованием методов предварительной сортировки и приготовляемые из нее фармацевтические композиции |
| NZ567627A (en) * | 2005-09-30 | 2011-08-26 | Boehringer Ingelheim Vetmed | Granulation process for making a divisible tablet containing meloxicam |
| TW200817047A (en) * | 2006-04-03 | 2008-04-16 | Teva Pharma | Drug microparticles |
| US8895141B2 (en) | 2008-08-18 | 2014-11-25 | Mitsubishi Shoji Foodtech Co., Ltd. | Excipient for compressed tablets comprising novel spherical mannitol |
| MX2012004177A (es) | 2009-10-12 | 2012-05-08 | Boehringer Ingelheim Vetmed | Recipiente para composiciones que comprenden meloxicam. |
| US20110218191A1 (en) * | 2010-03-03 | 2011-09-08 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the long term-treatment of kidney disorders in cats |
| US9149480B2 (en) | 2010-03-03 | 2015-10-06 | Boehringer Ingeleheim Vetmedica GmbH | Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats |
| US9795568B2 (en) | 2010-05-05 | 2017-10-24 | Boehringer Ingelheim Vetmedica Gmbh | Low concentration meloxicam tablets |
| CN104270961B (zh) | 2012-05-11 | 2017-03-15 | N·V·努特里奇亚 | 婴儿配方物及其制备 |
| EP3068239B2 (de) | 2013-11-11 | 2024-04-17 | N.V. Nutricia | Pulverförmige nährstoffzusammensetzung mit grossen lipidkügelchen |
| EP3555321A1 (de) * | 2016-12-13 | 2019-10-23 | Spx Flow Technology Danmark A/S | Verfahren zur herstellung eines lactosepulvers |
| CN110151725B (zh) * | 2019-06-26 | 2021-06-18 | 海南通用三洋药业有限公司 | 一种稳定的瑞舒伐他汀钙胶囊剂及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2088606A (en) * | 1936-04-24 | 1937-08-03 | David D Peebles | Manufacture of stable powdered products containing milk sugar |
| GB740255A (en) * | 1953-04-07 | 1955-11-09 | Lijempf Nv | Process for producing small lactose crystals |
| US2856318A (en) * | 1956-05-29 | 1958-10-14 | Foremost Dairies Inc | Lactose product and process of manufacture |
| US3639170A (en) * | 1970-05-01 | 1972-02-01 | Foremost Mckesson | Lactose product and method |
| US3802914A (en) * | 1972-04-10 | 1974-04-09 | Kraftco Corp | Method of treating lactose |
-
1986
- 1986-03-21 NL NL8600731A patent/NL8600731A/nl not_active Application Discontinuation
-
1987
- 1987-03-18 US US07/027,424 patent/US4802926A/en not_active Expired - Lifetime
- 1987-03-19 JP JP62065526A patent/JPS62265295A/ja active Pending
- 1987-03-20 EP EP87200524A patent/EP0239172B1/de not_active Expired - Lifetime
- 1987-03-20 DE DE8787200524T patent/DE3784260T2/de not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12214082B1 (en) | 2024-05-13 | 2025-02-04 | Leprino Foods Company | One pass spray dried lactose |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0239172A3 (en) | 1988-04-06 |
| DE3784260T2 (de) | 1993-09-16 |
| DE3784260D1 (de) | 1993-04-01 |
| EP0239172B1 (de) | 1993-02-24 |
| EP0239172A2 (de) | 1987-09-30 |
| US4802926A (en) | 1989-02-07 |
| JPS62265295A (ja) | 1987-11-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1B | A search report has been drawn up | ||
| BV | The patent application has lapsed |