NL8104976A - 2,6-c-dimethyltyrosine 1-d-aminozuur 2-epsilon-aminocapronzuur en gamma-aminoboterzuur 5-derivaten van methionine-enkefaline. - Google Patents

2,6-c-dimethyltyrosine 1-d-aminozuur 2-epsilon-aminocapronzuur en gamma-aminoboterzuur 5-derivaten van methionine-enkefaline. Download PDF

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Publication number
NL8104976A
NL8104976A NL8104976A NL8104976A NL8104976A NL 8104976 A NL8104976 A NL 8104976A NL 8104976 A NL8104976 A NL 8104976A NL 8104976 A NL8104976 A NL 8104976A NL 8104976 A NL8104976 A NL 8104976A
Authority
NL
Netherlands
Prior art keywords
compound
acid
amino
phenylalanyl
alkyl
Prior art date
Application number
NL8104976A
Other languages
English (en)
Dutch (nl)
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of NL8104976A publication Critical patent/NL8104976A/nl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/70—Enkephalins
    • C07K14/702—Enkephalins with at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NL8104976A 1980-11-03 1981-11-03 2,6-c-dimethyltyrosine 1-d-aminozuur 2-epsilon-aminocapronzuur en gamma-aminoboterzuur 5-derivaten van methionine-enkefaline. NL8104976A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20292080 1980-11-03
US06/202,920 US4316892A (en) 1980-11-03 1980-11-03 2,6-C-Dimethyltyrosine1 -D-amino acid2 -ε-amino caproic and γ aminobutyric acid5 derivatives of methionine enkephalin

Publications (1)

Publication Number Publication Date
NL8104976A true NL8104976A (nl) 1982-06-01

Family

ID=22751754

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8104976A NL8104976A (nl) 1980-11-03 1981-11-03 2,6-c-dimethyltyrosine 1-d-aminozuur 2-epsilon-aminocapronzuur en gamma-aminoboterzuur 5-derivaten van methionine-enkefaline.

Country Status (18)

Country Link
US (1) US4316892A (it)
JP (1) JPS57131748A (it)
AU (1) AU546107B2 (it)
BE (1) BE890963A (it)
CA (1) CA1178577A (it)
CH (1) CH649562A5 (it)
DE (1) DE3143599A1 (it)
DK (1) DK483481A (it)
ES (1) ES8306474A1 (it)
FR (1) FR2493311B1 (it)
GB (1) GB2086912B (it)
IT (1) IT1195324B (it)
NL (1) NL8104976A (it)
NO (1) NO813700L (it)
NZ (1) NZ198862A (it)
PT (1) PT73915B (it)
SE (1) SE446986B (it)
ZA (1) ZA817592B (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4603121A (en) * 1983-10-06 1986-07-29 G. D. Searle & Co. Enkephalin analogs
US4495178A (en) * 1983-10-06 1985-01-22 G. D. Searle & Co. Enkephalin analogs
US4599325A (en) * 1984-02-16 1986-07-08 G. D. Searle & Co. Substituted tyrosyl alanine dipeptide amides
US4760180A (en) * 1986-02-14 1988-07-26 G. D. Searle & Co. N-terminally substituted dipeptide amides
US4757153A (en) * 1986-02-14 1988-07-12 G. D. Searle & Co. Sulfide, sulfinyl and sulfone dipeptide amides
US4822775A (en) * 1986-02-14 1989-04-18 G. D. Searle & Co. Phenyl substituted dipeptide amides
US4880829A (en) * 1985-08-14 1989-11-14 G. D. Searle And Company Substituted dipeptide amides #3
EP0215297A3 (en) * 1985-08-14 1989-07-19 G.D. Searle & Co. Substituted dipeptide amides
ATE99698T1 (de) * 1985-10-14 1994-01-15 Nippon Zoki Pharmaceutical Co Peptide.
US4758675A (en) * 1986-07-14 1988-07-19 G. D. Searle & Co. 3-thiophene-substituted tyrosyl dipeptide amides
US4797470A (en) * 1986-07-14 1989-01-10 G. D. Searle & Co. O-substituted tyrosyl dipeptide amides
US4767744A (en) * 1986-07-14 1988-08-30 G. D. Searle & Co. Substituted tyrosyl methionyl dipeptide amides
EP1575390B1 (en) * 2002-12-03 2008-03-26 Velcro Industries B.V. Needling through carrier sheets to form loops

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4178371A (en) * 1977-12-15 1979-12-11 Reckitt & Colman Products Limited Tetrapeptide derivatives
US4261883A (en) * 1979-07-09 1981-04-14 The Regents Of The University Of California Novel N-aralkyl enkephalin amide analogs are provided having analgesic and opioid properties
JPS6038400B2 (ja) * 1979-08-10 1985-08-31 株式会社 大塚製薬工場 エンケファリン誘導体の製造法

Also Published As

Publication number Publication date
AU546107B2 (en) 1985-08-15
PT73915A (en) 1981-12-01
US4316892A (en) 1982-02-23
ES506783A0 (es) 1983-06-01
IT1195324B (it) 1988-10-12
DE3143599A1 (de) 1982-08-05
NZ198862A (en) 1985-09-13
NO813700L (no) 1982-05-04
ZA817592B (en) 1982-10-27
CA1178577A (en) 1984-11-27
GB2086912A (en) 1982-05-19
CH649562A5 (de) 1985-05-31
FR2493311A1 (fr) 1982-05-07
SE446986B (sv) 1986-10-20
AU7702481A (en) 1982-05-13
ES8306474A1 (es) 1983-06-01
JPS57131748A (en) 1982-08-14
FR2493311B1 (fr) 1986-04-25
GB2086912B (en) 1984-03-21
BE890963A (fr) 1982-03-01
PT73915B (en) 1983-04-29
DK483481A (da) 1982-05-04
SE8106441L (sv) 1982-05-04
IT8149623A0 (it) 1981-11-03

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BV The patent application has lapsed