NL7810909A - NEW DERIVATIVES OF 4-AMINO-2- (PIPERAZIN-1-YL OR - - HOMOPIPERAZIN-1-YL) -QUINAZOLINE. - Google Patents

NEW DERIVATIVES OF 4-AMINO-2- (PIPERAZIN-1-YL OR - - HOMOPIPERAZIN-1-YL) -QUINAZOLINE.

Info

Publication number
NL7810909A
NL7810909A NL7810909A NL7810909A NL7810909A NL 7810909 A NL7810909 A NL 7810909A NL 7810909 A NL7810909 A NL 7810909A NL 7810909 A NL7810909 A NL 7810909A NL 7810909 A NL7810909 A NL 7810909A
Authority
NL
Netherlands
Prior art keywords
homopiperazin
quinazoline
piperazin
amino
new derivatives
Prior art date
Application number
NL7810909A
Other languages
Dutch (nl)
Other versions
NL174549B (en
NL174549C (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NL7810909A publication Critical patent/NL7810909A/en
Publication of NL174549B publication Critical patent/NL174549B/en
Application granted granted Critical
Publication of NL174549C publication Critical patent/NL174549C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NLAANVRAGE7810909,A 1977-11-05 1978-11-02 4-AMINO-2- (PIPERAZIN-1-YL OR HOMOPIPERAZIN-1-YL) CHINAZOLINES, A METHOD FOR PREPARING SUCH A COMPOUND AND A METHOD FOR PREPARING PHARMACEUTICAL PREPARATIONS USING THESE COMPOUNDS. NL174549C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4612877 1977-11-05

Publications (3)

Publication Number Publication Date
NL7810909A true NL7810909A (en) 1979-05-08
NL174549B NL174549B (en) 1984-02-01
NL174549C NL174549C (en) 1984-07-02

Family

ID=10439957

Family Applications (2)

Application Number Title Priority Date Filing Date
NLAANVRAGE7810909,A NL174549C (en) 1977-11-05 1978-11-02 4-AMINO-2- (PIPERAZIN-1-YL OR HOMOPIPERAZIN-1-YL) CHINAZOLINES, A METHOD FOR PREPARING SUCH A COMPOUND AND A METHOD FOR PREPARING PHARMACEUTICAL PREPARATIONS USING THESE COMPOUNDS.
NL930062C NL930062I2 (en) 1977-11-05 1993-06-11 4-Amino-2- (piperazin-1-yl or homopiperazin-1-yl) quinazolines, and a method of preparing such a compound and a method of preparing pharmaceutical compositions using these compounds.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NL930062C NL930062I2 (en) 1977-11-05 1993-06-11 4-Amino-2- (piperazin-1-yl or homopiperazin-1-yl) quinazolines, and a method of preparing such a compound and a method of preparing pharmaceutical compositions using these compounds.

Country Status (36)

Country Link
JP (1) JPS5498792A (en)
AR (2) AR219562A1 (en)
AT (1) AT365186B (en)
AU (1) AU509329B2 (en)
BE (1) BE871771A (en)
CA (1) CA1088059A (en)
CH (1) CH643255A5 (en)
CS (2) CS207671B2 (en)
DD (1) DD139850A5 (en)
DE (1) DE2847623C2 (en)
DK (1) DK154082C (en)
EG (1) EG13594A (en)
ES (2) ES474805A1 (en)
FI (1) FI64366C (en)
FR (1) FR2407929A1 (en)
GR (1) GR81514B (en)
HK (1) HK94284A (en)
HU (1) HU176306B (en)
IE (1) IE47888B1 (en)
IL (1) IL55857A (en)
IN (1) IN148828B (en)
IT (1) IT1100919B (en)
KE (1) KE3350A (en)
LU (2) LU80470A1 (en)
MY (1) MY8500286A (en)
NL (2) NL174549C (en)
NO (1) NO150158C (en)
NZ (1) NZ188813A (en)
PH (1) PH13966A (en)
PL (2) PL119586B1 (en)
PT (1) PT68735A (en)
SE (1) SE437518B (en)
SU (1) SU816403A3 (en)
UA (1) UA8324A1 (en)
YU (2) YU40204B (en)
ZA (1) ZA786184B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985004658A1 (en) * 1984-04-04 1985-10-24 Takeda Chemical Industries, Ltd. 1,5-benzoxathiepine derivatives and their preparation
WO1985002617A1 (en) * 1983-12-14 1985-06-20 Takeda Chemical Industries. Ltd. 1,5-benzoxathiepin derivatives and process for their preparation
WO1986002644A1 (en) * 1984-11-01 1986-05-09 Takeda Chemical Industries, Ltd. 1,5-benzoxathiepin derivatives and process for their preparation
EP0849264A1 (en) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Novel polymorphic form of doxazosin mesylate (form I)
ES2282997T3 (en) * 1996-12-20 2007-10-16 Heumann Pcs Gmbh NEW POLYMORM FORM OF MESILATE AND DOXAZOSINE (FORM III).
EP0849265A1 (en) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Novel polymorphic form of doxazosin mesylate (form II)
TW448155B (en) * 1999-03-29 2001-08-01 Dev Center Biotechnology Method for producing amide compounds and quinazolin derivatives
EP1403263B1 (en) * 2002-09-27 2005-06-22 Council of Scientific and Industrial Research Process for the preparation of N-(2,3-dihydrobenzo 1,4 dioxin-2-carbonyl) piperazine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3663706A (en) * 1969-09-29 1972-05-16 Pfizer Use of 2,4-diaminoquinazolines as hypotensive agents
US3669968A (en) * 1970-05-21 1972-06-13 Pfizer Trialkoxy quinazolines

Also Published As

Publication number Publication date
AR223015A1 (en) 1981-07-15
DD139850A5 (en) 1980-01-23
IL55857A (en) 1982-07-30
NL174549B (en) 1984-02-01
PL210681A1 (en) 1979-11-05
IE782179L (en) 1979-05-05
IT7829434A0 (en) 1978-11-03
NL174549C (en) 1984-07-02
IT1100919B (en) 1985-09-28
AR219562A1 (en) 1980-08-29
ES8308559A1 (en) 1980-07-16
CA1088059A (en) 1980-10-21
NL930062I2 (en) 1993-11-16
PT68735A (en) 1978-12-01
CH643255A5 (en) 1984-05-30
AU4132278A (en) 1979-05-17
LU80470A1 (en) 1980-06-05
PL119419B1 (en) 1981-12-31
FI783347A (en) 1979-05-06
NO150158B (en) 1984-05-21
JPS5498792A (en) 1979-08-03
LU88331I2 (en) 1994-05-04
DK154082B (en) 1988-10-10
ZA786184B (en) 1979-10-31
FR2407929B1 (en) 1981-02-27
FR2407929A1 (en) 1979-06-01
YU40204B (en) 1985-08-31
NO783705L (en) 1979-05-08
NZ188813A (en) 1980-10-08
JPS5625233B2 (en) 1981-06-11
AU509329B2 (en) 1980-05-08
YU38683A (en) 1983-06-30
MY8500286A (en) 1985-12-31
ES474805A1 (en) 1980-01-16
FI64366C (en) 1983-11-10
AT365186B (en) 1981-12-28
PH13966A (en) 1980-11-12
SE437518B (en) 1985-03-04
IE47888B1 (en) 1984-07-11
IL55857A0 (en) 1979-01-31
HU176306B (en) 1981-01-28
EG13594A (en) 1982-03-31
NL930062I1 (en) 1993-09-01
DE2847623C2 (en) 1983-06-01
DK428678A (en) 1979-05-06
BE871771A (en) 1979-05-03
PL119586B1 (en) 1982-01-30
NO150158C (en) 1984-08-29
YU255378A (en) 1983-06-30
CS354491A3 (en) 1992-06-17
IN148828B (en) 1981-06-27
HK94284A (en) 1984-12-07
CS207671B2 (en) 1981-08-31
GR81514B (en) 1984-12-11
YU40419B (en) 1985-12-31
KE3350A (en) 1983-12-16
DK154082C (en) 1989-02-27
ES480121A0 (en) 1980-07-16
UA8324A1 (en) 1996-03-29
FI64366B (en) 1983-07-29
DE2847623A1 (en) 1979-05-23
ATA784378A (en) 1981-05-15
SE7811382L (en) 1979-05-06
SU816403A3 (en) 1981-03-23

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Legal Events

Date Code Title Description
A1A A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
AC1 Application for a supplementary protection certificate

Free format text: 930062, 930611

KC1 Grant of a supplementary protection certificate

Free format text: 930062, 981102, EXPIRES:20020401

V4 Discontinued because of reaching the maximum lifetime of a patent

Free format text: 981102