DK428678A - PROCEDURE FOR THE PREPARATION OF 4-AMINO-2- (PIPERAZIN-1-YL OR HOMOPIPERAZIN-1-YL) -QUINAZOLINES - Google Patents

PROCEDURE FOR THE PREPARATION OF 4-AMINO-2- (PIPERAZIN-1-YL OR HOMOPIPERAZIN-1-YL) -QUINAZOLINES

Info

Publication number
DK428678A
DK428678A DK428678A DK428678A DK428678A DK 428678 A DK428678 A DK 428678A DK 428678 A DK428678 A DK 428678A DK 428678 A DK428678 A DK 428678A DK 428678 A DK428678 A DK 428678A
Authority
DK
Denmark
Prior art keywords
homopiperazin
quinazolines
piperazin
amino
procedure
Prior art date
Application number
DK428678A
Other languages
Danish (da)
Other versions
DK154082C (en
DK154082B (en
Inventor
S F Campbell
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to US05/952,317 priority Critical patent/US4188390A/en
Publication of DK428678A publication Critical patent/DK428678A/en
Publication of DK154082B publication Critical patent/DK154082B/en
Application granted granted Critical
Publication of DK154082C publication Critical patent/DK154082C/en
Priority to BG096072A priority patent/BG60337B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK428678A 1977-11-05 1978-09-27 METHOD OF ANALOGUE FOR THE PREPARATION OF 4-AMINO-6,7-DIMETHOXY-2- (PIPERAZIN-1-YL OR HOMOPIPERAZIN-1-YL) -QUINAZOLINE COMPOUNDS OR PHARMACEUTICAL ACCEPTABLE ACID ADDITIONAL SALTS DK154082C (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US05/952,317 US4188390A (en) 1977-11-05 1978-10-18 Antihypertensive 4-amino-2-[4-(1,4-benzodioxan-2-carbonyl) piperazin-1-yl or homopiperazin-1-yl]quinazolines
BG096072A BG60337B2 (en) 1977-11-05 1992-03-16 4-amino-2-(4-)1,4-benzodioxan-2-carbonyl(piperazine-1-il or homopiperazine-1-il)quinazolines with antihypertension effect

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB4612877 1977-11-05
GB4612877 1977-11-05

Publications (3)

Publication Number Publication Date
DK428678A true DK428678A (en) 1979-05-06
DK154082B DK154082B (en) 1988-10-10
DK154082C DK154082C (en) 1989-02-27

Family

ID=10439957

Family Applications (1)

Application Number Title Priority Date Filing Date
DK428678A DK154082C (en) 1977-11-05 1978-09-27 METHOD OF ANALOGUE FOR THE PREPARATION OF 4-AMINO-6,7-DIMETHOXY-2- (PIPERAZIN-1-YL OR HOMOPIPERAZIN-1-YL) -QUINAZOLINE COMPOUNDS OR PHARMACEUTICAL ACCEPTABLE ACID ADDITIONAL SALTS

Country Status (36)

Country Link
JP (1) JPS5498792A (en)
AR (2) AR219562A1 (en)
AT (1) AT365186B (en)
AU (1) AU509329B2 (en)
BE (1) BE871771A (en)
CA (1) CA1088059A (en)
CH (1) CH643255A5 (en)
CS (2) CS207671B2 (en)
DD (1) DD139850A5 (en)
DE (1) DE2847623C2 (en)
DK (1) DK154082C (en)
EG (1) EG13594A (en)
ES (2) ES474805A1 (en)
FI (1) FI64366C (en)
FR (1) FR2407929A1 (en)
GR (1) GR81514B (en)
HK (1) HK94284A (en)
HU (1) HU176306B (en)
IE (1) IE47888B1 (en)
IL (1) IL55857A (en)
IN (1) IN148828B (en)
IT (1) IT1100919B (en)
KE (1) KE3350A (en)
LU (2) LU80470A1 (en)
MY (1) MY8500286A (en)
NL (2) NL174549C (en)
NO (1) NO150158C (en)
NZ (1) NZ188813A (en)
PH (1) PH13966A (en)
PL (2) PL119586B1 (en)
PT (1) PT68735A (en)
SE (1) SE437518B (en)
SU (1) SU816403A3 (en)
UA (1) UA8324A1 (en)
YU (2) YU40204B (en)
ZA (1) ZA786184B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985002617A1 (en) * 1983-12-14 1985-06-20 Takeda Chemical Industries. Ltd. 1,5-benzoxathiepin derivatives and process for their preparation
WO1986002644A1 (en) * 1984-11-01 1986-05-09 Takeda Chemical Industries, Ltd. 1,5-benzoxathiepin derivatives and process for their preparation
WO1985004658A1 (en) * 1984-04-04 1985-10-24 Takeda Chemical Industries, Ltd. 1,5-benzoxathiepine derivatives and their preparation
EP0849264A1 (en) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Novel polymorphic form of doxazosin mesylate (form I)
EP0849265A1 (en) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Novel polymorphic form of doxazosin mesylate (form II)
DE59611417D1 (en) * 1996-12-20 2007-03-29 Heumann Pharma Gmbh & Co New Polymorphic Form of Doxazosin Mesylate (Form III)
TW448155B (en) * 1999-03-29 2001-08-01 Dev Center Biotechnology Method for producing amide compounds and quinazolin derivatives
EP1403263B1 (en) * 2002-09-27 2005-06-22 Council of Scientific and Industrial Research Process for the preparation of N-(2,3-dihydrobenzo 1,4 dioxin-2-carbonyl) piperazine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3663706A (en) * 1969-09-29 1972-05-16 Pfizer Use of 2,4-diaminoquinazolines as hypotensive agents
US3669968A (en) * 1970-05-21 1972-06-13 Pfizer Trialkoxy quinazolines

Also Published As

Publication number Publication date
IE47888B1 (en) 1984-07-11
YU255378A (en) 1983-06-30
ES480121A0 (en) 1980-07-16
NZ188813A (en) 1980-10-08
ES474805A1 (en) 1980-01-16
SE7811382L (en) 1979-05-06
PL119419B1 (en) 1981-12-31
FI64366B (en) 1983-07-29
FI64366C (en) 1983-11-10
NL930062I2 (en) 1993-11-16
NL930062I1 (en) 1993-09-01
MY8500286A (en) 1985-12-31
CS207671B2 (en) 1981-08-31
IE782179L (en) 1979-05-05
JPS5498792A (en) 1979-08-03
GR81514B (en) 1984-12-11
IL55857A0 (en) 1979-01-31
AU4132278A (en) 1979-05-17
PT68735A (en) 1978-12-01
ZA786184B (en) 1979-10-31
KE3350A (en) 1983-12-16
EG13594A (en) 1982-03-31
IT1100919B (en) 1985-09-28
NL174549C (en) 1984-07-02
ATA784378A (en) 1981-05-15
NO783705L (en) 1979-05-08
LU80470A1 (en) 1980-06-05
AR219562A1 (en) 1980-08-29
AR223015A1 (en) 1981-07-15
ES8308559A1 (en) 1980-07-16
YU38683A (en) 1983-06-30
PL119586B1 (en) 1982-01-30
CA1088059A (en) 1980-10-21
FR2407929A1 (en) 1979-06-01
CH643255A5 (en) 1984-05-30
YU40419B (en) 1985-12-31
CS354491A3 (en) 1992-06-17
HU176306B (en) 1981-01-28
FR2407929B1 (en) 1981-02-27
NO150158B (en) 1984-05-21
JPS5625233B2 (en) 1981-06-11
IN148828B (en) 1981-06-27
IL55857A (en) 1982-07-30
AT365186B (en) 1981-12-28
YU40204B (en) 1985-08-31
NO150158C (en) 1984-08-29
AU509329B2 (en) 1980-05-08
BE871771A (en) 1979-05-03
NL7810909A (en) 1979-05-08
DK154082C (en) 1989-02-27
PH13966A (en) 1980-11-12
SE437518B (en) 1985-03-04
HK94284A (en) 1984-12-07
DK154082B (en) 1988-10-10
SU816403A3 (en) 1981-03-23
LU88331I2 (en) 1994-05-04
NL174549B (en) 1984-02-01
IT7829434A0 (en) 1978-11-03
DE2847623C2 (en) 1983-06-01
UA8324A1 (en) 1996-03-29
DD139850A5 (en) 1980-01-23
FI783347A (en) 1979-05-06
DE2847623A1 (en) 1979-05-23
PL210681A1 (en) 1979-11-05

Similar Documents

Publication Publication Date Title
DK63178A (en) PROCEDURE FOR THE PREPARATION OF PYRRODIN DERIVATIVES
DK110778A (en) PROCEDURE FOR THE PREPARATION OF 4-ACYLAMINO-PHENYL-ETHANOLAMINES
DK569678A (en) PROCEDURE FOR THE PREPARATION OF 2ALFA-CYANO-3-OXOSTEROIDS
DK484677A (en) PROCEDURE FOR THE PREPARATION OF FUROCUMARINES
DK172578A (en) PROCEDURE FOR THE PREPARATION OF ANILINE DERIVATIVES
DK146578A (en) PROCEDURE FOR THE PREPARATION OF INTERPHENYLENE 8-AZA-9-DIOXOTHIA-11% 12-SECOPROSTAGLANDINS
DK27078A (en) PROCEDURE FOR THE PREPARATION OF IMIDAZOQUINOLES OR SALTS THEREOF
DK428678A (en) PROCEDURE FOR THE PREPARATION OF 4-AMINO-2- (PIPERAZIN-1-YL OR HOMOPIPERAZIN-1-YL) -QUINAZOLINES
DK237978A (en) PROCEDURE FOR THE PREPARATION OF ALFAFLUOROMETHYL-ALFA-AMINOAL CANCIDS
DK511878A (en) PROCEDURE FOR THE PREPARATION OF IMIDAZOBENZOAZEPINES OR SALTS THEREOF
DK154949C (en) PROCEDURE FOR THE PREPARATION OF TRIFLUORMETHYLPHENOLS
DK50778A (en) PROCEDURE FOR THE PREPARATION OF OXADIAZOLOPYRIMIDINE DERIVATIVES
DK577078A (en) PROCEDURE FOR THE PREPARATION OF TRANS-4A-ARYLOCTAHYDRO-1H-2-PYRIDINES
DK71378A (en) PROCEDURE FOR THE PREPARATION OF HALOGENE-METHYLED DIPHENYLETHERS
DK50878A (en) PROCEDURE FOR THE PREPARATION OF OXADIAZOLOPYRIMIDINE DERIVATIVES
DK364578A (en) PROCEDURE FOR THE PREPARATION OF HYDROXYPHENYLHYDANTOIN
DK243178A (en) PROCEDURE FOR THE MANUFACTURE OF GUANIDINE DERIVATIVES
DK248978A (en) PROCEDURE FOR THE PREPARATION OF HYDROXY-ALFA-AMINOBENZYLPENICILLIN
DK353478A (en) PROCEDURE FOR THE PREPARATION OF URETHANIUM GROUP FOAMS
DK261278A (en) PROCEDURE FOR THE PREPARATION OF 24-DEHYDROVITAMIN D-3 DERIVATIVES
DK262178A (en) PROCEDURE FOR THE PREPARATION OF 2-KETO-L-GULOIC ACID OR ESTERES OR D-ENANTIOMERS
DK154778A (en) PROCEDURE FOR THE PREPARATION OF PHOSPHORYLED AMIDINES
DK339777A (en) PROCEDURE FOR THE PREPARATION OF 2-BENZYLPERHYDROAZEPINES
DK61778A (en) PROCEDURE FOR THE PREPARATION OF EVERNINOMIN DERIVATIVES
DK275378A (en) PROCEDURE FOR THE PREPARATION OF INDANDER DIVISIONS