NL7804509A - Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan. - Google Patents

Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan.

Info

Publication number
NL7804509A
NL7804509A NL7804509A NL7804509A NL7804509A NL 7804509 A NL7804509 A NL 7804509A NL 7804509 A NL7804509 A NL 7804509A NL 7804509 A NL7804509 A NL 7804509A NL 7804509 A NL7804509 A NL 7804509A
Authority
NL
Netherlands
Prior art keywords
novel
acid addition
addition salts
benzomorphan derivatives
benzomorphan
Prior art date
Application number
NL7804509A
Other languages
English (en)
Dutch (nl)
Original Assignee
Acf Chemiefarma Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acf Chemiefarma Nv filed Critical Acf Chemiefarma Nv
Priority to NL7804509A priority Critical patent/NL7804509A/xx
Priority to EP79101161A priority patent/EP0004960B1/en
Priority to DK157979A priority patent/DK157979A/da
Priority to DE7979101161T priority patent/DE2966325D1/de
Priority to FI791239A priority patent/FI67372C/fi
Priority to IT48786/79A priority patent/IT1115132B/it
Priority to AU46330/79A priority patent/AU529456B2/en
Priority to NZ190278A priority patent/NZ190278A/xx
Priority to IL57129A priority patent/IL57129A/xx
Priority to PT69536A priority patent/PT69536A/pt
Priority to AT0307579A priority patent/AT373585B/de
Priority to CA326,184A priority patent/CA1111422A/en
Priority to PH22415A priority patent/PH17142A/en
Priority to ES479928A priority patent/ES479928A1/es
Priority to HU79CE1211A priority patent/HU182470B/hu
Priority to JP5198179A priority patent/JPS54151979A/ja
Priority to ZA792005A priority patent/ZA792005B/xx
Priority to IE838/79A priority patent/IE48276B1/en
Publication of NL7804509A publication Critical patent/NL7804509A/xx
Priority to ES488134A priority patent/ES488134A1/es
Priority to FI833578A priority patent/FI68228C/fi
Priority to FI833577A priority patent/FI68227C/fi
Priority to US06/546,849 priority patent/US4473576A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
NL7804509A 1978-04-26 1978-04-26 Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan. NL7804509A (nl)

Priority Applications (22)

Application Number Priority Date Filing Date Title
NL7804509A NL7804509A (nl) 1978-04-26 1978-04-26 Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan.
EP79101161A EP0004960B1 (en) 1978-04-26 1979-04-17 9.9-dimethyl-6.7-benzomorphan derivatives, processes for their preparation and pharmaceutical compositions comprising them
DK157979A DK157979A (da) 1978-04-26 1979-04-17 Fremgangsmaade til fremstilling af benzomorphanderivater
DE7979101161T DE2966325D1 (en) 1978-04-26 1979-04-17 9.9-dimethyl-6.7-benzomorphan derivatives, processes for their preparation and pharmaceutical compositions comprising them
FI791239A FI67372C (fi) 1978-04-26 1979-04-17 Foerfarande foer framstaellning av analgetiskt och/eller morfinantagonistiskt aktiva 6,7-bensomorfanderivat
IT48786/79A IT1115132B (it) 1978-04-26 1979-04-19 Derivati del 6,7 benzomorfano loro preparazione e loro applicazione in terapeutica
CA326,184A CA1111422A (en) 1978-04-26 1979-04-24 6,7-benzomorphan derivatives
NZ190278A NZ190278A (en) 1978-04-26 1979-04-24 6,7-benzomorphan derivatives and pharmaceutical compositions
IL57129A IL57129A (en) 1978-04-26 1979-04-24 6,7-benzomorphan derivatives,their production and pharmaceutical compositions containing them
PT69536A PT69536A (fr) 1978-04-26 1979-04-24 Procede pour la preparation de nouveaux composes organiques a effet pharmaceutique
AT0307579A AT373585B (de) 1978-04-26 1979-04-24 Verfahren zur herstellung neuer, optisch aktiver oder racemischer 6,7-benzomorphan-derivate und deren saeureadditionssalze
AU46330/79A AU529456B2 (en) 1978-04-26 1979-04-24 6,7-benzomorphan derivatives
PH22415A PH17142A (en) 1978-04-26 1979-04-24 6,7-benzomorphans
ES479928A ES479928A1 (es) 1978-04-26 1979-04-25 Un procedimiento para la preparacion de derivados de 6,7-ben-zomorfan.
HU79CE1211A HU182470B (en) 1978-04-26 1979-04-25 Process for preparing 6,7-benzomorphan derivatives
JP5198179A JPS54151979A (en) 1978-04-26 1979-04-26 6*77benzomorphane derivative and its manufacture
ZA792005A ZA792005B (en) 1978-04-26 1979-04-26 6,7-benzomorphans
IE838/79A IE48276B1 (en) 1978-04-26 1979-08-08 9,9-dimethyl-6,7-benzomorphan derivatives,process for their preparation and pharmaceutical compositions comprising them
ES488134A ES488134A1 (es) 1978-04-26 1980-01-31 Un procedimiento para la preparacion de derivados de 6,7- benzomorfan
FI833578A FI68228C (fi) 1978-04-26 1983-10-03 Foerfarande foer framstaellning av analgetiskt och/eller morfinantagonistiskt aktiva 6,7-bensomorfanderivat
FI833577A FI68227C (fi) 1978-04-26 1983-10-03 Foerfarande foer framstaellning av analgetiskt och/eller morfinantagonistiskt aktiva 6,7-bentsomorfanderivat
US06/546,849 US4473576A (en) 1978-04-26 1983-10-31 Analgesic 9,9-dimethylbenzomorphanes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7804509A NL7804509A (nl) 1978-04-26 1978-04-26 Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan.

Publications (1)

Publication Number Publication Date
NL7804509A true NL7804509A (nl) 1979-10-30

Family

ID=19830738

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7804509A NL7804509A (nl) 1978-04-26 1978-04-26 Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan.

Country Status (19)

Country Link
US (1) US4473576A (it)
EP (1) EP0004960B1 (it)
JP (1) JPS54151979A (it)
AT (1) AT373585B (it)
AU (1) AU529456B2 (it)
CA (1) CA1111422A (it)
DE (1) DE2966325D1 (it)
DK (1) DK157979A (it)
ES (2) ES479928A1 (it)
FI (1) FI67372C (it)
HU (1) HU182470B (it)
IE (1) IE48276B1 (it)
IL (1) IL57129A (it)
IT (1) IT1115132B (it)
NL (1) NL7804509A (it)
NZ (1) NZ190278A (it)
PH (1) PH17142A (it)
PT (1) PT69536A (it)
ZA (1) ZA792005B (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4121821A1 (de) * 1991-07-02 1993-01-14 Boehringer Ingelheim Kg Neue benzomorphane und ihre verwendung als arzneimittel
US5607941A (en) * 1992-06-26 1997-03-04 Boehringer Ingelheim Kg Useful for treating neurodegenerative diseases
ATE314372T1 (de) * 1998-01-29 2006-01-15 Univ Monash Therapeutische verbindungen
DE19826365A1 (de) * 1998-06-12 1999-12-16 Gruenenthal Gmbh Verwendung von Benzomorphanderivaten als Analgetikum
DE10204276A1 (de) * 2002-02-02 2003-08-07 Boehringer Ingelheim Pharma N-Allyloxyethyl-1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocine und ihre Verwendung als Arzneimittel

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL130089C (it) * 1963-11-07
NL132138C (it) * 1966-05-20
IE34235B1 (en) * 1969-06-04 1975-03-19 Acf Chemiefarma Nv 6,7-benzomorphans and their preparation
US3883536A (en) * 1970-05-27 1975-05-13 Acf Chemiefarma Nv 3,3-Disubstituted-2-benzyl-4-piperidinols
DE2233088A1 (de) * 1972-06-30 1974-01-17 Schering Ag Benzomorphanderivate
US4020164A (en) * 1972-06-30 1977-04-26 Schering Aktiengesellschaft Benzomorphan derivatives
DE2315339A1 (de) * 1973-03-28 1974-10-17 Boehringer Sohn Ingelheim N-(heteroarylmethyl)-2'-hydroxy-5.9. 9-trimethyl-benzomorphane, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung
US4087532A (en) * 1974-03-09 1978-05-02 Boehringer Ingelheim Gmbh Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof
DE2437610A1 (de) * 1974-08-05 1976-02-26 Boehringer Sohn Ingelheim Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung
GB1513961A (en) * 1975-02-25 1978-06-14 Acf Chemiefarma Nv 6,7-benzomorphans method for their preparation and intermediates
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung

Also Published As

Publication number Publication date
ES488134A1 (es) 1980-09-16
ZA792005B (en) 1980-11-26
NZ190278A (en) 1981-12-15
PH17142A (en) 1984-06-04
FI67372C (fi) 1985-03-11
AT373585B (de) 1984-02-10
IL57129A (en) 1983-12-30
EP0004960A1 (en) 1979-10-31
JPS54151979A (en) 1979-11-29
IE790838L (en) 1979-10-26
IT7948786A0 (it) 1979-04-19
IT1115132B (it) 1986-02-03
ATA307579A (de) 1983-06-15
CA1111422A (en) 1981-10-27
FI67372B (fi) 1984-11-30
AU529456B2 (en) 1983-06-09
ES479928A1 (es) 1980-08-16
EP0004960B1 (en) 1983-10-19
US4473576A (en) 1984-09-25
FI791239A (fi) 1979-10-27
DE2966325D1 (en) 1983-11-24
HU182470B (en) 1984-01-30
AU4633079A (en) 1979-11-01
IE48276B1 (en) 1984-11-28
DK157979A (da) 1979-11-23
PT69536A (fr) 1979-05-01
IL57129A0 (en) 1979-07-25

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BV The patent application has lapsed