NL7712296A - Anti-neoplastic anthracycline di-saccharide derivs. - prepd. by reacting N-tri:fluoro-acetyl-daunomycin with a protected 1-halo-sugar, then removing the protecting gps. (BE 16.5.78) - Google Patents

Anti-neoplastic anthracycline di-saccharide derivs. - prepd. by reacting N-tri:fluoro-acetyl-daunomycin with a protected 1-halo-sugar, then removing the protecting gps. (BE 16.5.78)

Info

Publication number
NL7712296A
NL7712296A NL7712296A NL7712296A NL7712296A NL 7712296 A NL7712296 A NL 7712296A NL 7712296 A NL7712296 A NL 7712296A NL 7712296 A NL7712296 A NL 7712296A NL 7712296 A NL7712296 A NL 7712296A
Authority
NL
Netherlands
Prior art keywords
derivs
prepd
halo
sugar
reacting
Prior art date
Application number
NL7712296A
Other languages
English (en)
Dutch (nl)
Original Assignee
Farmaceutici Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia
Publication of NL7712296A publication Critical patent/NL7712296A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NL7712296A 1976-11-17 1977-11-08 Anti-neoplastic anthracycline di-saccharide derivs. - prepd. by reacting N-tri:fluoro-acetyl-daunomycin with a protected 1-halo-sugar, then removing the protecting gps. (BE 16.5.78) NL7712296A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB47835/76A GB1561507A (en) 1976-11-17 1976-11-17 Snthracycline disaccharides

Publications (1)

Publication Number Publication Date
NL7712296A true NL7712296A (en) 1978-05-19

Family

ID=10446415

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7712296A NL7712296A (en) 1976-11-17 1977-11-08 Anti-neoplastic anthracycline di-saccharide derivs. - prepd. by reacting N-tri:fluoro-acetyl-daunomycin with a protected 1-halo-sugar, then removing the protecting gps. (BE 16.5.78)

Country Status (17)

Country Link
US (1) US4169142A (de)
JP (1) JPS5363367A (de)
AT (1) AT352281B (de)
AU (1) AU518396B2 (de)
BE (1) BE860843A (de)
CA (1) CA1080702A (de)
CH (1) CH630929A5 (de)
DE (1) DE2751395C2 (de)
DK (1) DK503077A (de)
FR (1) FR2371461A1 (de)
GB (1) GB1561507A (de)
IE (1) IE46166B1 (de)
NL (1) NL7712296A (de)
NZ (1) NZ185678A (de)
SE (1) SE7712862L (de)
YU (1) YU271377A (de)
ZA (1) ZA776842B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK160616C (da) * 1979-02-03 1991-09-02 Zaidan Hojin Biseibutsu Fremgangsmaade til fremstilling af anthracyclinderivater eller syreadditionssalte deraf
PL124284B1 (en) * 1979-10-17 1983-01-31 Politechnika Gdanska Process for preparing n-glycosyl derivatives of antibiotics from anthracyclines group
JPS56156300A (en) * 1980-04-26 1981-12-02 Microbial Chem Res Found Novel preparative method of anthracyclin derivative
JPS57176995A (en) * 1981-04-23 1982-10-30 Sanraku Inc Novel anthracyclinone glycoside and its preparation
US4918172A (en) * 1987-10-06 1990-04-17 Sanraku Incorporated Anthracycline antibiotics
US4864859A (en) * 1988-07-25 1989-09-12 Allied-Signal Inc. Method for dynamically balancing a mechanism having a high speed rotating component
IT1262565B (it) * 1993-09-30 1996-07-04 Menarini Farma Ind Disaccaridi di antracicline, loro processi di preparazione e composizioni farmaceutiche che li contengono.
US20050208037A1 (en) * 2003-10-21 2005-09-22 Board Of Regents, The University Of Texas System Thioredoxin increases redox-cycling of anticancer agents thereby sensitizes cancer cells to apoptosis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3686163A (en) * 1968-05-14 1972-08-22 Farmaceutici Italia Dihydrodaunomycin antibiotic and derivatives thereof
GB1470860A (en) * 1974-10-29 1977-04-21 Farmaceutici Italia Anthracycline glycosides

Also Published As

Publication number Publication date
DE2751395C2 (de) 1982-10-28
AU3066377A (en) 1979-05-24
SE7712862L (sv) 1978-05-18
FR2371461B1 (de) 1981-11-20
CA1080702A (en) 1980-07-01
NZ185678A (en) 1978-12-18
CH630929A5 (de) 1982-07-15
IE46166L (en) 1978-05-17
DE2751395A1 (de) 1978-05-18
AT352281B (de) 1979-09-10
ZA776842B (en) 1978-11-29
BE860843A (fr) 1978-05-16
GB1561507A (en) 1980-02-20
US4169142A (en) 1979-09-25
ATA812177A (de) 1979-02-15
FR2371461A1 (fr) 1978-06-16
JPS5363367A (en) 1978-06-06
YU271377A (en) 1982-06-30
AU518396B2 (en) 1981-10-01
IE46166B1 (en) 1983-03-09
DK503077A (da) 1978-05-18

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Legal Events

Date Code Title Description
CNR Transfer of rights (patent application after its laying open for public inspection)

Free format text: FARMITALIA CARLO ERBA S.P.A.

BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BV The patent application has lapsed