JPS5547696A - Platinum-prednin complex and its preparation - Google Patents

Platinum-prednin complex and its preparation

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Publication number
JPS5547696A
JPS5547696A JP12067378A JP12067378A JPS5547696A JP S5547696 A JPS5547696 A JP S5547696A JP 12067378 A JP12067378 A JP 12067378A JP 12067378 A JP12067378 A JP 12067378A JP S5547696 A JPS5547696 A JP S5547696A
Authority
JP
Japan
Prior art keywords
prednin
formula
complex
diaquoplatinum
platinum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP12067378A
Other languages
Japanese (ja)
Inventor
Junzo Sunamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyo Jozo KK
Original Assignee
Toyo Jozo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyo Jozo KK filed Critical Toyo Jozo KK
Priority to JP12067378A priority Critical patent/JPS5547696A/en
Publication of JPS5547696A publication Critical patent/JPS5547696A/en
Pending legal-status Critical Current

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

NEW MATERIAL:A complex of diaquoplatinum (II) of the formula I [R1 and R2 are H, lower alkyl, or they form a group of formula II (R3 and R4 are H or lower alkyl groups)] with prednin of formula III.
EXAMPLE: Pt(prednin)4.(NO3)2(H2O)6.
USE: Antitumor agents, having a higher water-solubility and a lower toxicity than the diaquoplatinum (II) of formula I.
PROCESS: Prednin (P) of formula III having an antibacterial and an immunosuppresive actions is reacted with a diaquoplatinum (II) salt (S) of formula IV (X is anion having a smaller complexing ability than water and P; n is O or 1) of in an aqueous medium at a molar ratio of P to S preferably 1W4:1. X is preferably nitrate ion.
COPYRIGHT: (C)1980,JPO&Japio
JP12067378A 1978-09-29 1978-09-29 Platinum-prednin complex and its preparation Pending JPS5547696A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12067378A JPS5547696A (en) 1978-09-29 1978-09-29 Platinum-prednin complex and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12067378A JPS5547696A (en) 1978-09-29 1978-09-29 Platinum-prednin complex and its preparation

Publications (1)

Publication Number Publication Date
JPS5547696A true JPS5547696A (en) 1980-04-04

Family

ID=14792092

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12067378A Pending JPS5547696A (en) 1978-09-29 1978-09-29 Platinum-prednin complex and its preparation

Country Status (1)

Country Link
JP (1) JPS5547696A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS573051A (en) * 1980-06-09 1982-01-08 Matsushita Electric Ind Co Ltd Potential measurement device of electronic copying machine
EP0059911A1 (en) * 1981-03-09 1982-09-15 BASF Aktiengesellschaft Cis-platinous(II) complexes with saccharide derivatives as ligands

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS573051A (en) * 1980-06-09 1982-01-08 Matsushita Electric Ind Co Ltd Potential measurement device of electronic copying machine
EP0059911A1 (en) * 1981-03-09 1982-09-15 BASF Aktiengesellschaft Cis-platinous(II) complexes with saccharide derivatives as ligands

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