JPS55130992A - Novel platinum complex - Google Patents
Novel platinum complexInfo
- Publication number
- JPS55130992A JPS55130992A JP3923379A JP3923379A JPS55130992A JP S55130992 A JPS55130992 A JP S55130992A JP 3923379 A JP3923379 A JP 3923379A JP 3923379 A JP3923379 A JP 3923379A JP S55130992 A JPS55130992 A JP S55130992A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- diaminocyclopentane
- trans
- nitrate
- platinum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
NEW MATERIAL:Diaminocyclopentane platinum (II) complexes of formula I (R1 and R2 are same halogen or nitrate or incorporate to form one of groups of formula IIWIV or when one of them is a group of formula V, the other is nitrate; the conformation of diaminocyclopentane is trans-d- or trans-l-).
EXAMPLE: cis-Dichloro(trans-l-diaminocyclopentane) platinum (II) complex.
USE: Antitumorigenic agent.
PREPARATION: In an example, the reaction of K2PtX4 (X is halogen) with cyclopentanediamine is effected in an aqueous medium to form a compound of formula I (R1=R2=X). When necessary, the product is made to react with silver nitrate or silver sulfate to convert to a compound of formula I (R1=R2=NO3 or R1 and R2 are group of formula II). Moreover, when needed, the product is treated with potassium oxalate or sodium malonate to give other compounds of formula I.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3923379A JPS55130992A (en) | 1979-03-31 | 1979-03-31 | Novel platinum complex |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3923379A JPS55130992A (en) | 1979-03-31 | 1979-03-31 | Novel platinum complex |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS55130992A true JPS55130992A (en) | 1980-10-11 |
Family
ID=12547401
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3923379A Pending JPS55130992A (en) | 1979-03-31 | 1979-03-31 | Novel platinum complex |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55130992A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0098121A2 (en) * | 1982-06-24 | 1984-01-11 | Yoshinori Kidani | Platinum complexes, processes for their preparation, pharmaceutical compositions containing them and their use as medicaments |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS497224A (en) * | 1972-04-10 | 1974-01-22 | ||
JPS5331648A (en) * | 1976-09-06 | 1978-03-25 | Yoshinori Yoshitani | Cissplatinum complex of 1*22diaminocyclohexane isomer |
-
1979
- 1979-03-31 JP JP3923379A patent/JPS55130992A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS497224A (en) * | 1972-04-10 | 1974-01-22 | ||
JPS5331648A (en) * | 1976-09-06 | 1978-03-25 | Yoshinori Yoshitani | Cissplatinum complex of 1*22diaminocyclohexane isomer |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0098121A2 (en) * | 1982-06-24 | 1984-01-11 | Yoshinori Kidani | Platinum complexes, processes for their preparation, pharmaceutical compositions containing them and their use as medicaments |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS5716895A (en) | Platinum 2 complex and antitumor agent containing the same as active principle | |
ES472838A1 (en) | 3,4,5-Trihydroxypiperidine derivatives, process for their preparation and medicaments and fodder containing them. | |
JPS5287135A (en) | Bis-(m-amidinophenoxy) compound | |
JPS5390368A (en) | Preparation of cation-modified cellulose derivative | |
IL65943A0 (en) | New derivatives of n-dihydrothiazolyl-3-quinoline carboxamide,their salts,process for preparing them,their use as medicaments and the compositions containing them | |
JPS52136159A (en) | Anti/malignanttumor containing the same as active ingredients | |
JPS55130992A (en) | Novel platinum complex | |
JPS57156416A (en) | Platinum (2) complex and antitumor agent comprising it as active ingredient | |
JPS52285A (en) | Preparation of n1 *22tetrahydrofuryl**55fluorouracil | |
EG11798A (en) | Process for the preparation of(1-imidazolyl-(1-(4,(4"chlorophenyl)-phenoxy)-3,3-dimethylbutan-2-one and its salts,and their use as medicaments | |
JPS57150678A (en) | Purification of reaction mixture produced on manufacturing 2,3-epoxypropyltrialkylammonium chloride by treating chlorohydroxypropyltrialkylammonium chloride with alkali functional substance in aqueous medium | |
JPS56103192A (en) | Novel platinum complex | |
JPS5259186A (en) | Preparation of 3-cephem compounds by reduction | |
JPS539717A (en) | Preparation of sulfoxyimines | |
JPS5547696A (en) | Platinum-prednin complex and its preparation | |
JPS5321186A (en) | Penicillanic acid derivatives and their preparation | |
JPS5344572A (en) | 5-alkoxy-picolic acid, its preparation and hypotensives containing the same | |
JPS5767578A (en) | N-phthtalidy-5-fluorouracil derivative | |
JPS52111587A (en) | Preparation of 6-aminopenam carboxylic acid-1-oxide or its derivatives | |
JPS5772997A (en) | Novel oligomannoside and its preparation | |
JPS51133296A (en) | Processes for preparing 7-acylamino- 3-hydroxymethyl-2-cephem-4-carbox ylic acid derivatives | |
JPS5772996A (en) | Novel oligomannoside and its preparation | |
JPS5289678A (en) | Preparation of 1-(2-tetrahydrofuryl)-5-fluorouracil | |
GB1475650A (en) | Perchlorodiazafulvene and a process for its preparation | |
JPS532424A (en) | Preparation of p-xylene |