NL7613713A - Trifluormethylthio (en sulfonyl) derivaten van cyproheptadine-analogen. - Google Patents
Trifluormethylthio (en sulfonyl) derivaten van cyproheptadine-analogen.Info
- Publication number
- NL7613713A NL7613713A NL7613713A NL7613713A NL7613713A NL 7613713 A NL7613713 A NL 7613713A NL 7613713 A NL7613713 A NL 7613713A NL 7613713 A NL7613713 A NL 7613713A NL 7613713 A NL7613713 A NL 7613713A
- Authority
- NL
- Netherlands
- Prior art keywords
- trifluormethylthio
- cyproheptadine
- sulfonyl
- analogs
- derivatives
- Prior art date
Links
- RAHZWNYVWXNFOC-UHFFFAOYSA-N Sulphur dioxide Chemical class O=S=O RAHZWNYVWXNFOC-UHFFFAOYSA-N 0.000 title 1
- JJCFRYNCJDLXIK-UHFFFAOYSA-N cyproheptadine Chemical class C1CN(C)CCC1=C1C2=CC=CC=C2C=CC2=CC=CC=C21 JJCFRYNCJDLXIK-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/38—Halogen atoms or nitro radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/02—Magnesium compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/642,863 US4031222A (en) | 1975-12-22 | 1975-12-22 | Trifluoromethylthio (and sulfonyl) derivatives of cyproheptadine analogs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL7613713A true NL7613713A (nl) | 1977-06-24 |
Family
ID=24578354
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL7613713A NL7613713A (nl) | 1975-12-22 | 1976-12-09 | Trifluormethylthio (en sulfonyl) derivaten van cyproheptadine-analogen. |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US4031222A (de) |
| JP (1) | JPS5278880A (de) |
| AT (1) | AT363936B (de) |
| AU (1) | AU506996B2 (de) |
| BE (1) | BE849678A (de) |
| CA (1) | CA1085823A (de) |
| CH (7) | CH625790A5 (de) |
| DE (1) | DE2657978C3 (de) |
| DK (1) | DK550976A (de) |
| ES (6) | ES454468A1 (de) |
| FI (1) | FI763545A (de) |
| FR (1) | FR2336133A1 (de) |
| GB (1) | GB1519080A (de) |
| GR (1) | GR62010B (de) |
| HU (1) | HU175018B (de) |
| IE (1) | IE44362B1 (de) |
| IL (1) | IL51103A (de) |
| LU (1) | LU76382A1 (de) |
| NL (1) | NL7613713A (de) |
| NO (1) | NO146359C (de) |
| NZ (1) | NZ182868A (de) |
| PH (1) | PH14088A (de) |
| PL (4) | PL116941B1 (de) |
| PT (1) | PT65956B (de) |
| SE (1) | SE7613796L (de) |
| ZA (1) | ZA767579B (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4148903A (en) * | 1977-07-28 | 1979-04-10 | Merck & Co., Inc. | Antipsychotic, antiserotonin and antihistaminic pyrrolo[2,1-b][3]benzazepines |
| US4132796A (en) * | 1977-12-01 | 1979-01-02 | Merck & Co., Inc. | Antipsychotic 3-trifluoromethylsulfinyl analogs of cyproheptadine |
| US4285956A (en) * | 1978-05-12 | 1981-08-25 | Kefalas A/S | Xanthene and thioxanthene derivatives, compositions thereof and treatment therewith |
| US4195091A (en) * | 1978-11-15 | 1980-03-25 | Merck & Co., Inc. | Appetite stimulating pyrrolo[2,1-b][3]benzazepines |
| EP0012988B1 (de) * | 1979-01-02 | 1983-04-27 | Merck & Co. Inc. | Links- und rechtsdrehende Enantiomere von 3-Halocyproheptadinen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzung |
| US4275070A (en) * | 1979-05-21 | 1981-06-23 | Merck & Co., Inc. | Antipsychotic pharmaceutical compositions of the levorotatory enantiomers of 3-methoxycyproheptadine and an analog thereof |
| US4220651A (en) * | 1979-05-21 | 1980-09-02 | Merck & Co., Inc. | Antipsychotic levorotatory enantiomers of 3-halocyproheptadines, analogs and derivatives |
| EP0019797A1 (de) * | 1979-05-21 | 1980-12-10 | Merck & Co. Inc. | Links- und rechtsdrehende Enantiomere von 3-Methoxycyproheptadin und ihre Analoge, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen mit antipsychotischer Wirkung |
| US5231105A (en) * | 1987-06-02 | 1993-07-27 | Ajinomoto Co., Inc. | Ethylamine derivatives and antihypertensives containing the same |
| US5393890A (en) | 1988-06-02 | 1995-02-28 | Ajinomoto Co., Inc. | Piperidine derivatives and hypotensives containing the same |
| US5250681A (en) * | 1988-06-02 | 1993-10-05 | Ajinomoto Co., Inc. | Piperidine derivatives and hypotensives containing the same |
| US5114919A (en) * | 1990-02-26 | 1992-05-19 | Merck & Co., Inc. | Adjuncts in cancer chemotherapy |
| US4996321A (en) * | 1990-02-26 | 1991-02-26 | Merck & Co., Inc. | Dibenzo[a,d]cycloheptenylidene compounds |
| US5021426A (en) * | 1990-02-26 | 1991-06-04 | Merck & Co., Inc. | Method of traeting malaria with cyproheptadine derivatives |
| CN103130708B (zh) * | 2011-12-01 | 2016-08-10 | 上海药明康德新药开发有限公司 | 一种n-叔丁氧羰基-4-硝基哌啶的制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3851059A (en) * | 1970-02-05 | 1974-11-26 | Merck & Co Inc | Method for the stimulation of appetite in patients |
-
1975
- 1975-12-22 US US05/642,863 patent/US4031222A/en not_active Expired - Lifetime
-
1976
- 1976-12-08 DK DK550976A patent/DK550976A/da unknown
- 1976-12-08 SE SE7613796A patent/SE7613796L/xx not_active Application Discontinuation
- 1976-12-09 NL NL7613713A patent/NL7613713A/xx unknown
- 1976-12-09 NO NO764188A patent/NO146359C/no unknown
- 1976-12-09 FI FI763545A patent/FI763545A/fi not_active Application Discontinuation
- 1976-12-13 HU HU76ME2035A patent/HU175018B/hu unknown
- 1976-12-13 PT PT65956A patent/PT65956B/pt unknown
- 1976-12-13 NZ NZ182868A patent/NZ182868A/xx unknown
- 1976-12-14 LU LU76382A patent/LU76382A1/xx unknown
- 1976-12-14 AU AU20528/76A patent/AU506996B2/en not_active Expired
- 1976-12-14 IL IL51103A patent/IL51103A/xx unknown
- 1976-12-14 CH CH1571276A patent/CH625790A5/de not_active IP Right Cessation
- 1976-12-16 CA CA267,998A patent/CA1085823A/en not_active Expired
- 1976-12-16 FR FR7637940A patent/FR2336133A1/fr active Granted
- 1976-12-16 GB GB52626/76A patent/GB1519080A/en not_active Expired
- 1976-12-16 GR GR52418A patent/GR62010B/el unknown
- 1976-12-17 IE IE2771/76A patent/IE44362B1/en unknown
- 1976-12-20 PL PL1976222975A patent/PL116941B1/pl unknown
- 1976-12-20 PL PL1976222974A patent/PL122145B1/pl unknown
- 1976-12-20 PL PL1976222973A patent/PL116947B1/pl unknown
- 1976-12-20 AT AT0943376A patent/AT363936B/de not_active IP Right Cessation
- 1976-12-20 PL PL1976194577A patent/PL116346B1/pl unknown
- 1976-12-21 BE BE173486A patent/BE849678A/xx not_active IP Right Cessation
- 1976-12-21 DE DE2657978A patent/DE2657978C3/de not_active Expired
- 1976-12-21 ES ES454468A patent/ES454468A1/es not_active Expired
- 1976-12-21 PH PH19273A patent/PH14088A/en unknown
- 1976-12-21 ZA ZA00767579A patent/ZA767579B/xx unknown
- 1976-12-22 JP JP51153529A patent/JPS5278880A/ja active Pending
-
1978
- 1978-02-01 ES ES466553A patent/ES466553A1/es not_active Expired
- 1978-02-01 ES ES466550A patent/ES466550A1/es not_active Expired
- 1978-02-01 ES ES466549A patent/ES466549A1/es not_active Expired
- 1978-02-01 ES ES466551A patent/ES466551A1/es not_active Expired
- 1978-02-01 ES ES466552A patent/ES466552A1/es not_active Expired
-
1980
- 1980-11-26 CH CH877080A patent/CH626344A5/de not_active IP Right Cessation
- 1980-11-26 CH CH877180A patent/CH626345A5/de not_active IP Right Cessation
- 1980-11-26 CH CH877280A patent/CH626346A5/de not_active IP Right Cessation
- 1980-11-26 CH CH876880A patent/CH627167A5/de not_active IP Right Cessation
- 1980-11-26 CH CH876980A patent/CH626343A5/de not_active IP Right Cessation
-
1981
- 1981-06-01 CH CH357381A patent/CH631164A5/de not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SE7612365L (sv) | L-fenyl-2-oxo-pyrrolidin-4-karbonsyraderivat | |
| SE7608840L (sv) | Prostansyraderivat | |
| NL7606654A (nl) | Imidylbenzeencarbonzuurderivaten. | |
| IT1068948B (it) | Preparazione di polisolfuri di alchile | |
| NL7613461A (nl) | Windhaak of uithouder. | |
| RO72997A (ro) | Procedeu pentru prepararea benzoilureido-nitro-difenileteri | |
| NL7613713A (nl) | Trifluormethylthio (en sulfonyl) derivaten van cyproheptadine-analogen. | |
| IT1063101B (it) | Preparazione di floruri di zolfo | |
| FR2301253A1 (fr) | Derives de la | |
| AR211273A1 (es) | Procendimiento de preparacion de nuevas (fenoxi-4-fenil)1-piperazinas | |
| IT1061827B (it) | Miscele di fumo | |
| NL7613714A (nl) | Trifluormethyldhioderivaten van cyproheptadine. | |
| TR19245A (tr) | 3-fenoksibenzaldehidlerin imali | |
| IT1074066B (it) | Giroscopio | |
| IT1041584B (it) | Procedimento per la preparazione dell idrazodicarbonammide | |
| IT1057715B (it) | Procedimento per l ossiclorurazione dell etano | |
| SE7601566L (sv) | Prostansyraderivat | |
| ZA761858B (en) | Novel anthelmintic substituted sulfonamide derivatives | |
| IT1061476B (it) | Preparazione di un ossazolo | |
| DK570976A (da) | Hidtil ukendte sperminderivater | |
| ZA765403B (en) | Derivatives of 2-substituted-hydroxyanilino-hexahydro-2h-benzo(alpha)quinolizines | |
| BE840992A (fr) | Desucrage de la melasse | |
| DK243376A (da) | Acylaminoderivater | |
| SE7602743L (sv) | Prostansyraderivat | |
| SE7605743L (sv) | Gyroskop |