NL7613160A - Werkwijze voor het bereiden van nieuwe gesubsti- tueerde imidazo(1.2-a)pyridinen. - Google Patents

Werkwijze voor het bereiden van nieuwe gesubsti- tueerde imidazo(1.2-a)pyridinen.

Info

Publication number
NL7613160A
NL7613160A NL7613160A NL7613160A NL7613160A NL 7613160 A NL7613160 A NL 7613160A NL 7613160 A NL7613160 A NL 7613160A NL 7613160 A NL7613160 A NL 7613160A NL 7613160 A NL7613160 A NL 7613160A
Authority
NL
Netherlands
Prior art keywords
pyridins
new substituted
substituted imidazo
preparing new
preparing
Prior art date
Application number
NL7613160A
Other languages
English (en)
Dutch (nl)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NL7613160A publication Critical patent/NL7613160A/xx

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/42Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/53Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/86Hydrazides; Thio or imino analogues thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
NL7613160A 1975-12-09 1976-11-25 Werkwijze voor het bereiden van nieuwe gesubsti- tueerde imidazo(1.2-a)pyridinen. NL7613160A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63903475A 1975-12-09 1975-12-09

Publications (1)

Publication Number Publication Date
NL7613160A true NL7613160A (nl) 1977-06-13

Family

ID=24562456

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7613160A NL7613160A (nl) 1975-12-09 1976-11-25 Werkwijze voor het bereiden van nieuwe gesubsti- tueerde imidazo(1.2-a)pyridinen.

Country Status (25)

Country Link
US (1) US4096264A (pt)
JP (1) JPS5273896A (pt)
AR (1) AR222960A1 (pt)
AT (1) AT361475B (pt)
AU (1) AU505045B2 (pt)
BE (1) BE849123A (pt)
CA (1) CA1084930A (pt)
CH (1) CH626362A5 (pt)
DE (1) DE2655681A1 (pt)
DK (1) DK529276A (pt)
ES (1) ES453947A1 (pt)
FI (1) FI763343A (pt)
FR (1) FR2334357A1 (pt)
GB (1) GB1524589A (pt)
GR (1) GR62009B (pt)
IL (1) IL51024A (pt)
NL (1) NL7613160A (pt)
NO (1) NO764025L (pt)
NZ (1) NZ182756A (pt)
OA (1) OA05506A (pt)
PH (1) PH12259A (pt)
PL (1) PL103751B1 (pt)
PT (1) PT65915B (pt)
SE (1) SE430504B (pt)
ZA (1) ZA767331B (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105767A (en) * 1977-03-28 1978-08-08 Merck & Co., Inc. Imidazo [1,2-a] pyridines substituted with a thienyl, thiazolyl, or thiadiazolyl group
US4154835A (en) * 1977-10-12 1979-05-15 Merck & Co., Inc. Anthelmintic imidazo [1,2-a] pyridines
US4250174A (en) * 1979-05-02 1981-02-10 Merck & Co., Inc. 3-Substituted imidazo [1,2-A] pyridines
US4221796A (en) * 1979-09-19 1980-09-09 E. R. Squibb & Sons, Inc. Substituted imidazolo-pyridines and method
ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
US4507481A (en) * 1983-07-29 1985-03-26 Pennwalt Corporation Pyrrolo[1,2-a]imidazoles and imidazo[1,2-a]pyridines
IT1173196B (it) * 1984-02-02 1987-06-18 Bellon Roger Schoum Rbs Pharma Composti imidazopiridinici farmacologicamente attivi
US5214138A (en) * 1989-12-20 1993-05-25 Case Western Reserve University Imidazopyridinium compound and processes for isolating, identifying, and chemically synthesizing same
ATE119774T1 (de) * 1990-07-30 1995-04-15 Takeda Chemical Industries Ltd Imidazopyridinderivate und ihre verwendung.
US6358971B1 (en) 1998-05-20 2002-03-19 Eli Lilly And Company Anti-viral compounds
EP1077701A4 (en) * 1998-05-20 2002-03-20 Lilly Co Eli ANTI-VIRAL COMPOUNDS
DE10117184A1 (de) * 2001-04-05 2002-10-17 Gruenenthal Gmbh Substituierte Imidazol[1,2-a]-pyridin-3-yl-amid- und -aminverbindungen
DE602005015833D1 (de) * 2004-03-19 2009-09-17 Warner Lambert Co Imidazopyridin- und imidazopyrimidin-derivate als antibakterielle mittel
US7544702B2 (en) * 2004-08-12 2009-06-09 Amgen Inc. Bisaryl-sulfonamides
CL2008001626A1 (es) * 2007-06-05 2009-06-05 Takeda Pharmaceuticals Co Compuestos derivados de heterociclos fusionados, agente farmaceutico que los comprende y su uso en la profilaxis y tratamiento del cancer.
US8431608B2 (en) 2007-08-17 2013-04-30 Icagen Inc. Heterocycles as potassium channel modulators
CA2696631A1 (en) * 2007-08-17 2009-02-26 Icagen, Inc. Heterocycles as potassium channel modulators
EP2181987B9 (en) * 2007-08-23 2014-09-03 Takeda Pharmaceutical Company Limited 2-Carbonylaminobenzothiazoles and their use for the prophylaxis and treatment of cancer
EP2184285B1 (en) * 2007-08-29 2015-11-04 Takeda Pharmaceutical Company Limited Heterocyclic compound and use thereof
JPWO2009128520A1 (ja) 2008-04-18 2011-08-04 塩野義製薬株式会社 Pi3k阻害活性を有する複素環化合物
WO2009136663A1 (en) * 2008-05-08 2009-11-12 Takeda Pharmaceutical Company Limited Fused heterocyclic derivatives and use thereof
EP2399921B1 (en) * 2008-12-01 2015-08-12 Takeda Pharmaceutical Company Limited Heterocyclic compound and use thereof
JO3101B1 (ar) * 2008-12-02 2017-09-20 Takeda Pharmaceuticals Co مشتقات بنزوثيازول كعوامل مضادة للسرطان
CA2771190C (en) 2009-08-17 2020-01-21 Memorial Sloan-Kettering Cancer Center Heat shock protein binding compounds, compositions, and methods for making and using same
BR112016026470A8 (pt) 2014-05-13 2021-07-20 Memorial Sloan Kettering Cancer Center composto modulador de hsp70, composição farmacêutica que o compreende e uso do referido composto

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3701780A (en) * 1970-09-18 1972-10-31 Merck & Co Inc Imidazo(1,2-a)pyridines
JPS5124517B1 (pt) * 1971-03-15 1976-07-24

Also Published As

Publication number Publication date
IL51024A0 (en) 1977-01-31
JPS6126545B2 (pt) 1986-06-20
CH626362A5 (pt) 1981-11-13
BE849123A (fr) 1977-06-07
GR62009B (en) 1979-02-15
AU505045B2 (en) 1979-11-08
NZ182756A (en) 1979-11-01
DE2655681A1 (de) 1977-06-16
US4096264A (en) 1978-06-20
FR2334357A1 (fr) 1977-07-08
JPS5273896A (en) 1977-06-21
IL51024A (en) 1981-12-31
CA1084930A (en) 1980-09-02
ZA767331B (en) 1978-07-26
FI763343A (pt) 1977-06-10
PT65915A (en) 1977-01-01
SE7613128L (sv) 1977-06-10
AR222960A1 (es) 1981-07-15
AT361475B (de) 1981-03-10
AU2010276A (en) 1978-06-08
SE430504B (sv) 1983-11-21
ATA901876A (de) 1980-08-15
ES453947A1 (es) 1978-03-01
PL103751B1 (pl) 1979-07-31
OA05506A (fr) 1981-04-30
GB1524589A (en) 1978-09-13
NO764025L (pt) 1977-06-10
PH12259A (en) 1978-12-12
DK529276A (da) 1977-06-10
PT65915B (en) 1978-11-07
FR2334357B1 (pt) 1982-10-15

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
BV The patent application has lapsed