NL7602332A - Werkwijze ter bereiding van para-benzoezuurderi- vaten, alsmede geneeskundige preparaten die deze verbindingen als serumlipide-verlagende component bevatten. - Google Patents

Werkwijze ter bereiding van para-benzoezuurderi- vaten, alsmede geneeskundige preparaten die deze verbindingen als serumlipide-verlagende component bevatten.

Info

Publication number
NL7602332A
NL7602332A NL7602332A NL7602332A NL7602332A NL 7602332 A NL7602332 A NL 7602332A NL 7602332 A NL7602332 A NL 7602332A NL 7602332 A NL7602332 A NL 7602332A NL 7602332 A NL7602332 A NL 7602332A
Authority
NL
Netherlands
Prior art keywords
compounds
benzoic acid
preparations containing
acid products
medicinal preparations
Prior art date
Application number
NL7602332A
Other languages
English (en)
Dutch (nl)
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of NL7602332A publication Critical patent/NL7602332A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C229/54Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C229/60Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in meta- or para- positions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63Esters of sulfonic acids
    • C07C309/64Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C07C309/66Methanesulfonates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL7602332A 1975-03-12 1976-03-05 Werkwijze ter bereiding van para-benzoezuurderi- vaten, alsmede geneeskundige preparaten die deze verbindingen als serumlipide-verlagende component bevatten. NL7602332A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/557,550 US4185115A (en) 1975-03-12 1975-03-12 Antilipidemic para-[aryl(alkyl or alkenyl)amino]-benzoic acid derivatives

Publications (1)

Publication Number Publication Date
NL7602332A true NL7602332A (nl) 1976-09-14

Family

ID=24225890

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7602332A NL7602332A (nl) 1975-03-12 1976-03-05 Werkwijze ter bereiding van para-benzoezuurderi- vaten, alsmede geneeskundige preparaten die deze verbindingen als serumlipide-verlagende component bevatten.

Country Status (24)

Country Link
US (1) US4185115A (xx)
JP (1) JPS51113838A (xx)
AR (1) AR215241A1 (xx)
AU (1) AU504690B2 (xx)
BE (1) BE839382A (xx)
CH (1) CH628614A5 (xx)
CS (1) CS212758B2 (xx)
DD (1) DD125926A5 (xx)
DE (1) DE2609962A1 (xx)
ES (1) ES445994A1 (xx)
FR (2) FR2303534A1 (xx)
GB (1) GB1535967A (xx)
HK (1) HK69179A (xx)
HU (1) HU173416B (xx)
IE (1) IE44285B1 (xx)
IL (1) IL49012A (xx)
MX (1) MX3788E (xx)
NL (1) NL7602332A (xx)
PL (1) PL112967B1 (xx)
RO (1) RO71822A (xx)
SE (1) SE7602869L (xx)
SU (1) SU803856A3 (xx)
YU (1) YU47676A (xx)
ZA (1) ZA76902B (xx)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2814798A1 (de) * 1977-04-07 1978-10-19 Dow Chemical Co 4-(2-thienylmethylamino)-benzoesaeure- verbindungen
US4178385A (en) 1978-03-03 1979-12-11 The Dow Chemical Company Method for treating hyperlipidemia in primates using 4-((4-fluorophenylmethyl)amino)benzoic acid
US4181737A (en) 1978-05-18 1980-01-01 The Dow Chemical Company 4-((3-Methoxyphenyl)amino)benzoic acid, a method for treating hyperlipidemia, and compositions thereof
US4192884A (en) 1977-04-07 1980-03-11 The Dow Chemical Company Substituted 4-(((thienyl)methyl)-amino)benzoic acids and a method for treating hypolipidemia
US4206223A (en) * 1979-01-05 1980-06-03 The Dow Chemical Company Method for treating hyperglycemia in mammals using 4-(((1,3-benzodioxol-5-yl)methyl)amino)benzoic acid or derivatives thereof
US4207330A (en) * 1978-07-03 1980-06-10 The Dow Chemical Company Method for treating hyperglycemia in mammals using arylamino benzoic acids
US4263320A (en) * 1979-06-04 1981-04-21 The Dow Chemical Company Hypoglycemic phenylpropynylamino benzoic acids

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1576841A (en) * 1977-01-22 1980-10-15 Beecham Group Ltd Substituted n-acyl phenylamine compounds having hypolipidaemic activity
IL56517A0 (en) * 1978-02-02 1979-03-12 American Cyanamid Co Novel 4-(cycloalkyl or cyclalkenyl substituted) amino, alkylamino or alkenylamino benzoic acids, salts and derivatives
US4230878A (en) 1978-03-08 1980-10-28 American Cyanamid Company Hypolipidemic and antiatherosclerotic 4-[(cyclopropyl alkyl)amino]benzoic acids and derivatives
EP0006452B1 (en) * 1978-06-23 1983-02-16 The Dow Chemical Company Hypoglycemic phenylpropynylamino benzoic acids, their salts, pharmaceutical compositions containing said compounds and their application
US4143151A (en) * 1978-07-03 1979-03-06 The Dow Chemical Company Method for treating hyperglycemia in mammals using arylamino benzoic acids
US4281019A (en) * 1979-02-01 1981-07-28 American Cyanamid Company 4-[(Unsaturated or cyclopropylated alkyl)amino]phenyl compounds useful as hypolipidemic and antiatherosclerotic agents
US4375478A (en) * 1982-03-02 1983-03-01 Abbott Laboratories Aminobenzoic acid derivatives
US7214825B2 (en) * 2003-10-17 2007-05-08 Honeywell International Inc. O-(3-chloropropenyl) hydroxylamine free base
WO2008121570A1 (en) * 2007-03-29 2008-10-09 Irm Llc Compounds and methods for modulating g protein-coupled receptors
CN109206333A (zh) * 2018-10-16 2019-01-15 河南师范大学 一种具有抗菌活性的苯佐卡因单取代衍生物的合成方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3868416A (en) * 1973-10-01 1975-02-25 American Cyanamid Co Hypolipidemic 4-(monoalkylamino)benzoic acid derivatives
GB1576007A (en) * 1976-02-11 1980-10-01 Beecham Group Ltd Hypolipidaemic compositions

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2814798A1 (de) * 1977-04-07 1978-10-19 Dow Chemical Co 4-(2-thienylmethylamino)-benzoesaeure- verbindungen
FR2386542A1 (fr) * 1977-04-07 1978-11-03 Dow Chemical Co Composes de l'acide 4-(2-thienylmethylamino)benzoique, leur procede de preparation et leur utilisation dans le traitement des hyperlipidemies
US4192884A (en) 1977-04-07 1980-03-11 The Dow Chemical Company Substituted 4-(((thienyl)methyl)-amino)benzoic acids and a method for treating hypolipidemia
US4178385A (en) 1978-03-03 1979-12-11 The Dow Chemical Company Method for treating hyperlipidemia in primates using 4-((4-fluorophenylmethyl)amino)benzoic acid
US4181737A (en) 1978-05-18 1980-01-01 The Dow Chemical Company 4-((3-Methoxyphenyl)amino)benzoic acid, a method for treating hyperlipidemia, and compositions thereof
US4207330A (en) * 1978-07-03 1980-06-10 The Dow Chemical Company Method for treating hyperglycemia in mammals using arylamino benzoic acids
US4206223A (en) * 1979-01-05 1980-06-03 The Dow Chemical Company Method for treating hyperglycemia in mammals using 4-(((1,3-benzodioxol-5-yl)methyl)amino)benzoic acid or derivatives thereof
US4263320A (en) * 1979-06-04 1981-04-21 The Dow Chemical Company Hypoglycemic phenylpropynylamino benzoic acids

Also Published As

Publication number Publication date
CH628614A5 (de) 1982-03-15
YU47676A (en) 1983-04-30
PL112967B1 (en) 1980-11-29
FR2303534A1 (fr) 1976-10-08
AR215241A1 (es) 1979-09-28
IE44285B1 (en) 1981-10-07
SE7602869L (sv) 1976-12-06
BE839382A (fr) 1976-09-10
FR2436132A1 (fr) 1980-04-11
ES445994A1 (es) 1977-10-01
US4185115A (en) 1980-01-22
HK69179A (en) 1979-10-05
IL49012A0 (en) 1976-04-30
FR2303534B1 (xx) 1981-08-28
AU504690B2 (en) 1979-10-25
DD125926A5 (xx) 1977-06-01
IE44285L (en) 1976-09-12
SU803856A3 (ru) 1981-02-07
ZA76902B (en) 1977-01-26
AU1103676A (en) 1977-08-18
CS212758B2 (en) 1982-03-26
MX3788E (es) 1981-07-20
JPS51113838A (en) 1976-10-07
DE2609962A1 (de) 1976-09-30
IL49012A (en) 1980-12-31
HU173416B (hu) 1979-05-28
RO71822A (ro) 1982-02-01
GB1535967A (en) 1978-12-13

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