NL7602332A - Werkwijze ter bereiding van para-benzoezuurderi- vaten, alsmede geneeskundige preparaten die deze verbindingen als serumlipide-verlagende component bevatten. - Google Patents
Werkwijze ter bereiding van para-benzoezuurderi- vaten, alsmede geneeskundige preparaten die deze verbindingen als serumlipide-verlagende component bevatten.Info
- Publication number
- NL7602332A NL7602332A NL7602332A NL7602332A NL7602332A NL 7602332 A NL7602332 A NL 7602332A NL 7602332 A NL7602332 A NL 7602332A NL 7602332 A NL7602332 A NL 7602332A NL 7602332 A NL7602332 A NL 7602332A
- Authority
- NL
- Netherlands
- Prior art keywords
- compounds
- benzoic acid
- preparations containing
- acid products
- medicinal preparations
- Prior art date
Links
- 239000005711 Benzoic acid Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 210000002966 serum Anatomy 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C229/60—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in meta- or para- positions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
- C07C309/66—Methanesulfonates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/557,550 US4185115A (en) | 1975-03-12 | 1975-03-12 | Antilipidemic para-[aryl(alkyl or alkenyl)amino]-benzoic acid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL7602332A true NL7602332A (nl) | 1976-09-14 |
Family
ID=24225890
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL7602332A NL7602332A (nl) | 1975-03-12 | 1976-03-05 | Werkwijze ter bereiding van para-benzoezuurderi- vaten, alsmede geneeskundige preparaten die deze verbindingen als serumlipide-verlagende component bevatten. |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4185115A (xx) |
| JP (1) | JPS51113838A (xx) |
| AR (1) | AR215241A1 (xx) |
| AU (1) | AU504690B2 (xx) |
| BE (1) | BE839382A (xx) |
| CH (1) | CH628614A5 (xx) |
| CS (1) | CS212758B2 (xx) |
| DD (1) | DD125926A5 (xx) |
| DE (1) | DE2609962A1 (xx) |
| ES (1) | ES445994A1 (xx) |
| FR (2) | FR2303534A1 (xx) |
| GB (1) | GB1535967A (xx) |
| HK (1) | HK69179A (xx) |
| HU (1) | HU173416B (xx) |
| IE (1) | IE44285B1 (xx) |
| IL (1) | IL49012A (xx) |
| MX (1) | MX3788E (xx) |
| NL (1) | NL7602332A (xx) |
| PL (1) | PL112967B1 (xx) |
| RO (1) | RO71822A (xx) |
| SE (1) | SE7602869L (xx) |
| SU (1) | SU803856A3 (xx) |
| YU (1) | YU47676A (xx) |
| ZA (1) | ZA76902B (xx) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2814798A1 (de) * | 1977-04-07 | 1978-10-19 | Dow Chemical Co | 4-(2-thienylmethylamino)-benzoesaeure- verbindungen |
| US4178385A (en) | 1978-03-03 | 1979-12-11 | The Dow Chemical Company | Method for treating hyperlipidemia in primates using 4-((4-fluorophenylmethyl)amino)benzoic acid |
| US4181737A (en) | 1978-05-18 | 1980-01-01 | The Dow Chemical Company | 4-((3-Methoxyphenyl)amino)benzoic acid, a method for treating hyperlipidemia, and compositions thereof |
| US4192884A (en) | 1977-04-07 | 1980-03-11 | The Dow Chemical Company | Substituted 4-(((thienyl)methyl)-amino)benzoic acids and a method for treating hypolipidemia |
| US4206223A (en) * | 1979-01-05 | 1980-06-03 | The Dow Chemical Company | Method for treating hyperglycemia in mammals using 4-(((1,3-benzodioxol-5-yl)methyl)amino)benzoic acid or derivatives thereof |
| US4207330A (en) * | 1978-07-03 | 1980-06-10 | The Dow Chemical Company | Method for treating hyperglycemia in mammals using arylamino benzoic acids |
| US4263320A (en) * | 1979-06-04 | 1981-04-21 | The Dow Chemical Company | Hypoglycemic phenylpropynylamino benzoic acids |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1576841A (en) * | 1977-01-22 | 1980-10-15 | Beecham Group Ltd | Substituted n-acyl phenylamine compounds having hypolipidaemic activity |
| IL56517A0 (en) * | 1978-02-02 | 1979-03-12 | American Cyanamid Co | Novel 4-(cycloalkyl or cyclalkenyl substituted) amino, alkylamino or alkenylamino benzoic acids, salts and derivatives |
| US4230878A (en) | 1978-03-08 | 1980-10-28 | American Cyanamid Company | Hypolipidemic and antiatherosclerotic 4-[(cyclopropyl alkyl)amino]benzoic acids and derivatives |
| EP0006452B1 (en) * | 1978-06-23 | 1983-02-16 | The Dow Chemical Company | Hypoglycemic phenylpropynylamino benzoic acids, their salts, pharmaceutical compositions containing said compounds and their application |
| US4143151A (en) * | 1978-07-03 | 1979-03-06 | The Dow Chemical Company | Method for treating hyperglycemia in mammals using arylamino benzoic acids |
| US4281019A (en) * | 1979-02-01 | 1981-07-28 | American Cyanamid Company | 4-[(Unsaturated or cyclopropylated alkyl)amino]phenyl compounds useful as hypolipidemic and antiatherosclerotic agents |
| US4375478A (en) * | 1982-03-02 | 1983-03-01 | Abbott Laboratories | Aminobenzoic acid derivatives |
| US7214825B2 (en) * | 2003-10-17 | 2007-05-08 | Honeywell International Inc. | O-(3-chloropropenyl) hydroxylamine free base |
| WO2008121570A1 (en) * | 2007-03-29 | 2008-10-09 | Irm Llc | Compounds and methods for modulating g protein-coupled receptors |
| CN109206333A (zh) * | 2018-10-16 | 2019-01-15 | 河南师范大学 | 一种具有抗菌活性的苯佐卡因单取代衍生物的合成方法和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3868416A (en) * | 1973-10-01 | 1975-02-25 | American Cyanamid Co | Hypolipidemic 4-(monoalkylamino)benzoic acid derivatives |
| GB1576007A (en) * | 1976-02-11 | 1980-10-01 | Beecham Group Ltd | Hypolipidaemic compositions |
-
1975
- 1975-03-12 US US05/557,550 patent/US4185115A/en not_active Expired - Lifetime
-
1976
- 1976-02-11 IL IL49012A patent/IL49012A/xx unknown
- 1976-02-12 AU AU11036/76A patent/AU504690B2/en not_active Expired
- 1976-02-16 GB GB6047/76A patent/GB1535967A/en not_active Expired
- 1976-02-16 ZA ZA902A patent/ZA76902B/xx unknown
- 1976-02-24 AR AR262358A patent/AR215241A1/es active
- 1976-02-26 YU YU00476/76A patent/YU47676A/xx unknown
- 1976-02-27 SE SE7602869A patent/SE7602869L/xx not_active Application Discontinuation
- 1976-03-05 NL NL7602332A patent/NL7602332A/xx not_active Application Discontinuation
- 1976-03-09 HU HU76AE461A patent/HU173416B/hu unknown
- 1976-03-10 FR FR7606862A patent/FR2303534A1/fr active Granted
- 1976-03-10 BE BE165004A patent/BE839382A/xx unknown
- 1976-03-10 DE DE19762609962 patent/DE2609962A1/de not_active Withdrawn
- 1976-03-11 CS CS761599A patent/CS212758B2/cs unknown
- 1976-03-11 MX MX7664U patent/MX3788E/es unknown
- 1976-03-11 RO RO7685064A patent/RO71822A/ro unknown
- 1976-03-11 PL PL1976187839A patent/PL112967B1/pl unknown
- 1976-03-11 IE IE514/76A patent/IE44285B1/en unknown
- 1976-03-12 CH CH313876A patent/CH628614A5/de not_active IP Right Cessation
- 1976-03-12 JP JP51026980A patent/JPS51113838A/ja active Pending
- 1976-03-12 DD DD191825A patent/DD125926A5/xx unknown
- 1976-03-12 ES ES445994A patent/ES445994A1/es not_active Expired
- 1976-03-12 SU SU762332503A patent/SU803856A3/ru active
-
1979
- 1979-07-10 FR FR7917907A patent/FR2436132A1/fr not_active Withdrawn
- 1979-09-27 HK HK691/79A patent/HK69179A/xx unknown
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2814798A1 (de) * | 1977-04-07 | 1978-10-19 | Dow Chemical Co | 4-(2-thienylmethylamino)-benzoesaeure- verbindungen |
| FR2386542A1 (fr) * | 1977-04-07 | 1978-11-03 | Dow Chemical Co | Composes de l'acide 4-(2-thienylmethylamino)benzoique, leur procede de preparation et leur utilisation dans le traitement des hyperlipidemies |
| US4192884A (en) | 1977-04-07 | 1980-03-11 | The Dow Chemical Company | Substituted 4-(((thienyl)methyl)-amino)benzoic acids and a method for treating hypolipidemia |
| US4178385A (en) | 1978-03-03 | 1979-12-11 | The Dow Chemical Company | Method for treating hyperlipidemia in primates using 4-((4-fluorophenylmethyl)amino)benzoic acid |
| US4181737A (en) | 1978-05-18 | 1980-01-01 | The Dow Chemical Company | 4-((3-Methoxyphenyl)amino)benzoic acid, a method for treating hyperlipidemia, and compositions thereof |
| US4207330A (en) * | 1978-07-03 | 1980-06-10 | The Dow Chemical Company | Method for treating hyperglycemia in mammals using arylamino benzoic acids |
| US4206223A (en) * | 1979-01-05 | 1980-06-03 | The Dow Chemical Company | Method for treating hyperglycemia in mammals using 4-(((1,3-benzodioxol-5-yl)methyl)amino)benzoic acid or derivatives thereof |
| US4263320A (en) * | 1979-06-04 | 1981-04-21 | The Dow Chemical Company | Hypoglycemic phenylpropynylamino benzoic acids |
Also Published As
| Publication number | Publication date |
|---|---|
| CH628614A5 (de) | 1982-03-15 |
| YU47676A (en) | 1983-04-30 |
| PL112967B1 (en) | 1980-11-29 |
| FR2303534A1 (fr) | 1976-10-08 |
| AR215241A1 (es) | 1979-09-28 |
| IE44285B1 (en) | 1981-10-07 |
| SE7602869L (sv) | 1976-12-06 |
| BE839382A (fr) | 1976-09-10 |
| FR2436132A1 (fr) | 1980-04-11 |
| ES445994A1 (es) | 1977-10-01 |
| US4185115A (en) | 1980-01-22 |
| HK69179A (en) | 1979-10-05 |
| IL49012A0 (en) | 1976-04-30 |
| FR2303534B1 (xx) | 1981-08-28 |
| AU504690B2 (en) | 1979-10-25 |
| DD125926A5 (xx) | 1977-06-01 |
| IE44285L (en) | 1976-09-12 |
| SU803856A3 (ru) | 1981-02-07 |
| ZA76902B (en) | 1977-01-26 |
| AU1103676A (en) | 1977-08-18 |
| CS212758B2 (en) | 1982-03-26 |
| MX3788E (es) | 1981-07-20 |
| JPS51113838A (en) | 1976-10-07 |
| DE2609962A1 (de) | 1976-09-30 |
| IL49012A (en) | 1980-12-31 |
| HU173416B (hu) | 1979-05-28 |
| RO71822A (ro) | 1982-02-01 |
| GB1535967A (en) | 1978-12-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BV | The patent application has lapsed |