NL7111164A - - Google Patents

Info

Publication number
NL7111164A
NL7111164A NL7111164A NL7111164A NL7111164A NL 7111164 A NL7111164 A NL 7111164A NL 7111164 A NL7111164 A NL 7111164A NL 7111164 A NL7111164 A NL 7111164A NL 7111164 A NL7111164 A NL 7111164A
Authority
NL
Netherlands
Prior art keywords
stream
light
sheath
photometer
sheathed
Prior art date
Application number
NL7111164A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NL7111164A publication Critical patent/NL7111164A/xx

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404Handling flow, e.g. hydrodynamic focusing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N21/05Flow-through cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N2021/0346Capillary cells; Microcells

Landscapes

  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Optical Measuring Cells (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

There is provided a method and apparatus for optical analysis by photometry of a substance flowing in a liquid stream within a coaxial sheath stream of a transparent liquid. The sheath stream, flowing in the same direction, entrains the inner stream so as to confine it concentrically. A photometer is used which includes a light source on one side of the sheathed stream in a position to direct light onto the inner stream which is cylindrical, the outer or sheath stream also being cylindrical. The photometer also includes a light detector externally of the sheathed stream in an angular position to detect the photometric results of impingement of light on the contents of the inner stream. Refraction of light at the interfaces of the sheath stream is compensated by varying the radius of the inner stream through the control of the flow of one stream with reference to the other.
NL7111164A 1970-08-28 1971-08-13 NL7111164A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6781970A 1970-08-28 1970-08-28

Publications (1)

Publication Number Publication Date
NL7111164A true NL7111164A (en) 1972-03-01

Family

ID=22078614

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7111164A NL7111164A (en) 1970-08-28 1971-08-13

Country Status (9)

Country Link
US (1) US3661460A (en)
AU (1) AU445066B2 (en)
BE (1) BE770541A (en)
CA (1) CA936017A (en)
CH (1) CH552807A (en)
DE (1) DE2142237C3 (en)
FR (1) FR2106060A5 (en)
GB (1) GB1321917A (en)
NL (1) NL7111164A (en)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3826364A (en) * 1972-05-22 1974-07-30 Univ Leland Stanford Junior Particle sorting method and apparatus
US3861800A (en) * 1972-07-27 1975-01-21 Becton Dickinson Co Particle counter independent of flow rate
US3871770A (en) * 1973-06-04 1975-03-18 Nuclear Data Inc Hydrodynamic focusing method and apparatus
USRE29141E (en) * 1973-06-14 1977-02-22 Coulter Electronics, Inc. Apparatus for orienting generally flat particles for sensing
US3893766A (en) * 1973-06-14 1975-07-08 Coulter Electronics Apparatus for orienting generally flat particles for slit-scan photometry
DE2543310C2 (en) * 1975-09-27 1982-04-29 Gesellschaft für Strahlen- und Umweltforschung mbH, 8000 München Device for counting and classifying particles suspended in a liquid
US4408877A (en) * 1979-04-10 1983-10-11 Ernst Leitz Wetzlar Gmbh Device for hydrodynamic focussing of a particle-suspension in a liquid flow cytophotometer
NO144002C (en) * 1979-04-10 1981-05-27 Norsk Hydro S Inst For Kreftfo DEVICE FOR USE IN LIQUID PHOTOMETRY
US4284412A (en) * 1979-07-13 1981-08-18 Ortho Diagnostics, Inc. Method and apparatus for automated identification and enumeration of specified blood cell subclasses
DE2934691C2 (en) * 1979-08-28 1988-06-16 Fresenius AG, 6380 Bad Homburg Method for carrying out analyzes using the flow method and measuring device therefor
EP0046345A3 (en) * 1980-08-15 1982-03-03 Ortho Diagnostic Systems Inc. Controlled hydrodynamic flow in flow cytometry systems
US4447883A (en) * 1981-05-26 1984-05-08 Technicon Instruments Corporation Coincidence-error correcting apparatus and method
DE3315194A1 (en) * 1982-04-29 1983-11-03 International Remote Imaging Systems Inc., 91311 Chatsworth, Calif. METHOD FOR SEPARATING PARTICLES FLOWING IN A FLUID SAMPLE
CA1194315A (en) * 1982-08-16 1985-10-01 Technicon Instruments Corporation Volumetric pumping apparatus and method for supplying fluids to sheath stream flow cells
US4683212A (en) * 1982-09-30 1987-07-28 Technicon Instruments Corporation Random access single channel sheath stream apparatus
US4565448A (en) * 1983-03-11 1986-01-21 E. I. Du Pont De Nemours And Company Particle counting apparatus
US4606631A (en) * 1983-05-12 1986-08-19 Kabushiki Kaisha Toshiba Particle counter
GB2172713B (en) * 1985-03-22 1988-12-21 Philips Nv Spectrometer
JPH0336914Y2 (en) * 1985-05-17 1991-08-05
US4983038A (en) * 1987-04-08 1991-01-08 Hitachi, Ltd. Sheath flow type flow-cell device
US4971912A (en) * 1987-07-14 1990-11-20 Technicon Instruments Corporation Apparatus and method for the separation of immiscible liquids
DE3820902A1 (en) * 1988-06-21 1989-12-28 Basf Ag ARRANGEMENT FOR MEASURING THE DEGREE OF DISPERSION IN FLOWING SUSPENSIONS
JPH0718785B2 (en) * 1988-09-19 1995-03-06 株式会社日立製作所 Flow cell device
US5194909A (en) * 1990-12-04 1993-03-16 Tycko Daniel H Apparatus and method for measuring volume and hemoglobin concentration of red blood cells
US5370842A (en) * 1991-11-29 1994-12-06 Canon Kabushiki Kaisha Sample measuring device and sample measuring system
GB9405028D0 (en) * 1994-03-15 1994-04-27 Counting Tech Ltd Fluid diluter
US5643796A (en) * 1994-10-14 1997-07-01 University Of Washington System for sensing droplet formation time delay in a flow cytometer
US5602349A (en) * 1994-10-14 1997-02-11 The University Of Washington Sample introduction system for a flow cytometer
US6861265B1 (en) 1994-10-14 2005-03-01 University Of Washington Flow cytometer droplet formation system
US5602039A (en) * 1994-10-14 1997-02-11 The University Of Washington Flow cytometer jet monitor system
EP0786078B1 (en) * 1994-10-14 2004-01-07 University of Washington System and method for high speed flow cytometer droplet formation
US5593564A (en) * 1995-07-24 1997-01-14 Hewlett-Packard Company Microcolumn-microcolumn flow interface and method
EP2264427B1 (en) 1997-01-31 2017-05-03 Xy, Llc Optical apparatus with focussing reflector for converging radiation onto a flow of particles, and related method of analysis
US5819948A (en) * 1997-08-21 1998-10-13 Van Den Engh; Gerrit J. Particle separating apparatus and method
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
US6071689A (en) 1997-12-31 2000-06-06 Xy, Inc. System for improving yield of sexed embryos in mammals
US6248590B1 (en) 1998-02-27 2001-06-19 Cytomation, Inc. Method and apparatus for flow cytometry
DE69938000T2 (en) 1998-07-30 2008-04-30 XY, Inc., Fort Collins SYSTEM FOR THE ARTIFICIAL NON-SURGICAL OCCUPATION OF HORSES
US6507400B1 (en) 1999-02-27 2003-01-14 Mwi, Inc. Optical system for multi-part differential particle discrimination and an apparatus using the same
US7024316B1 (en) 1999-10-21 2006-04-04 Dakocytomation Colorado, Inc. Transiently dynamic flow cytometer analysis system
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
US6263745B1 (en) * 1999-12-03 2001-07-24 Xy, Inc. Flow cytometer nozzle and flow cytometer sample handling methods
US6646742B1 (en) 2000-02-19 2003-11-11 Mwi, Inc. Optical device and method for multi-angle laser light scatter
NZ522613A (en) 2000-05-09 2005-08-26 Xy Inc Method and apparatus for sorting X-chromosome bearing and Y-chromosome bearing populations of spermatozoa and particle differentiation
US7242474B2 (en) * 2004-07-27 2007-07-10 Cox James A Cytometer having fluid core stream position control
AU2001269795B2 (en) * 2000-06-12 2006-07-20 Xy, Inc. Integrated herd management system utilizing isolated populations of x-chromosome bearing and y-chromosome bearing spermatozoa
CA2468774C (en) 2000-11-29 2015-06-30 George E. Seidel System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
WO2002092247A1 (en) 2001-05-17 2002-11-21 Cytomation, Inc. Flow cytometer with active automated optical alignment system
US20030211009A1 (en) * 2001-05-18 2003-11-13 Buchanan Kris S. Rapid multi-material sample input system
EP1348943A3 (en) 2002-03-25 2003-12-17 Sysmex Corporation Sheath liquid for particle analyzer
US11243494B2 (en) 2002-07-31 2022-02-08 Abs Global, Inc. Multiple laminar flow-based particle and cellular separation with laser steering
WO2004012837A2 (en) 2002-08-01 2004-02-12 Xy, Inc. Low pressure sperm cell separation system
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
JP2005535346A (en) 2002-08-15 2005-11-24 エックスワイ,インコーポレイテッド High resolution flow cytometer
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
EP2306174B1 (en) 2003-03-28 2016-05-11 Inguran, LLC Flow cytometry nozzle for orienting particles and corresponding method
EP1625203B1 (en) 2003-05-15 2015-04-08 Xy, Llc Efficient haploid cell sorting for flow cytometer systems
CA2561519C (en) 2004-03-29 2017-08-22 Monsanto Technology Llc Sperm dispersions for use in insemination
US7256882B2 (en) * 2004-06-21 2007-08-14 Bgi Instruments, Inc. Photometer device and method
AR049732A1 (en) 2004-07-22 2006-08-30 Monsanto Co PROCESS TO ENRICH A Sperm Cell Population
USRE46559E1 (en) * 2004-07-27 2017-09-26 Beckman Coulter, Inc. Enhancing flow cytometry discrimination with geometric transformation
US7618770B2 (en) * 2005-07-29 2009-11-17 Xy, Inc. Methods and apparatus for reducing protein content in sperm cell extenders
US10908066B2 (en) 2010-11-16 2021-02-02 1087 Systems, Inc. Use of vibrational spectroscopy for microfluidic liquid measurement
JP5852834B2 (en) * 2011-10-04 2016-02-03 アズビル株式会社 Evaluation system for particle detector and evaluation method for particle detector
US9746412B2 (en) 2012-05-30 2017-08-29 Iris International, Inc. Flow cytometer
US8961904B2 (en) 2013-07-16 2015-02-24 Premium Genetics (Uk) Ltd. Microfluidic chip
EP3063529A2 (en) 2013-10-30 2016-09-07 Premium Genetics (UK) Ltd. Microfluidic system and method with focused energy apparatus
US11796449B2 (en) 2013-10-30 2023-10-24 Abs Global, Inc. Microfluidic system and method with focused energy apparatus
EP3259579B1 (en) 2015-02-19 2022-09-14 1087 Systems, Inc. Scanning infrared measurement system
BR112020023607A2 (en) 2018-05-23 2021-02-17 Abs Global, Inc. systems and methods for focusing particles on microchannels
EP4245140A3 (en) 2019-04-18 2024-01-17 ABS Global, Inc. System and process for continuous addition of cryoprotectant
US11628439B2 (en) 2020-01-13 2023-04-18 Abs Global, Inc. Single-sheath microfluidic chip

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2732753A (en) * 1956-01-31 o konski
US2731877A (en) * 1956-01-24 clamann
US2875666A (en) * 1953-07-13 1959-03-03 Ohio Commw Eng Co Method of simultaneously counting red and white blood cells
US2920525A (en) * 1956-08-13 1960-01-12 Arthur V Appel Apparatus for automatically counting and sizing airborne particles
NL132814C (en) * 1963-07-24
US3560754A (en) * 1965-11-17 1971-02-02 Ibm Photoelectric particle separator using time delay
US3523733A (en) * 1966-01-05 1970-08-11 Technicon Corp Method and apparatus for particle counting
US3440866A (en) * 1966-09-01 1969-04-29 Research Corp Prothrombin timer apparatus and method
US3504183A (en) * 1966-09-12 1970-03-31 Iit Res Inst Particle counter using a variable test volume
US3515884A (en) * 1967-05-17 1970-06-02 Toa Electric Co Ltd Detecting and counting apparatus for particles suspended in a liquid

Also Published As

Publication number Publication date
DE2142237A1 (en) 1972-03-02
CA936017A (en) 1973-10-30
FR2106060A5 (en) 1972-04-28
GB1321917A (en) 1973-07-04
US3661460A (en) 1972-05-09
CH552807A (en) 1974-08-15
BE770541A (en) 1972-01-27
DE2142237B2 (en) 1974-01-10
AU3143671A (en) 1973-01-25
DE2142237C3 (en) 1974-08-15
AU445066B2 (en) 1974-02-14

Similar Documents

Publication Publication Date Title
FR2106060A5 (en)
SE7414184L (en)
FI935128A0 (en) Bestaemningar with velvet maongfaldiga
FR2359415A1 (en) OPTICAL MEASURING DEVICE TO DETERMINE THE CONCENTRATIONS OF SUBSTANCES
CA1030362A (en) Opto-electrical measuring apparatus for determining the relative hemoglobin content of an illuminated solution by evaluating its light absorption
CA1014637A (en) Optical particle detector with light scattering test device
SE8100194L (en) FOTOMETERKUVETT
ES434970A1 (en) Process and device for measuring antigen-antibody reactions
GB1395838A (en) Photometer apparatus
EP0344461A3 (en) Device for calibrating a non-dispersive infrared photometer
FR2316596B1 (en)
US3518009A (en) Colorimeter flow cell
ES383447A1 (en) Apparatus for measuring the light passing through a liquid sample in a closed flexible walled chamber
EP0185285A3 (en) Liquid level measurement apparatus
GB1271172A (en) An arrangement for measuring the refractive index of liquids
GB1303927A (en)
US2935908A (en) Apparatus for chromatographic analysis
GB2001752A (en) Optical detector device
JPS57111423A (en) Measuring device for absorption intensity of infrared ray by atr method
JPS55144529A (en) Optical device for measuring microplate
JPS51132757A (en) Optical observation device
JPS56140240A (en) Photometer for blood coagulation measurement
JPS5679238A (en) Detector for trace of blood
FR2254994A5 (en) Small sample atomic absorption spectrophotometer - uses Joule effect heating to atomise sample by vaporisation
JPS5317765A (en) Liquid level detector