| 
            
              US3475466A
              (en)
            
            *
            
           | 
          1965-08-30 | 
          1969-10-28 | 
          Schering Corp | 
          Novel 17,21-diesters of 16alpha-methyl-9alpha,11beta-dichloro-1,4- pregnadienes 
        | 
        
        
          | 
            
              US3422193A
              (en)
            
            *
            
           | 
          1966-08-11 | 
          1969-01-14 | 
          Schering Corp | 
          17-mono esters of corticoids 
        | 
        
        
          | 
            
              IT1061787B
              (it)
            
            *
            
           | 
          1967-03-01 | 
          1983-04-30 | 
          Vismara Francesco Spa | 
          Miglioramenti relativi alla preparazione di 17 benzoato di betametazone 
        | 
        
        
          | 
            
              GB1281689A
              (en)
            
            *
            
           | 
          1968-10-14 | 
          1972-07-12 | 
          Glaxo Lab Ltd | 
          Steroid 21-phosphates 
      | 
        
        
          | 
            
              US3694471A
              (en)
            
            *
            
           | 
          1970-06-08 | 
          1972-09-26 | 
          Warner Lambert Pharmaceutical | 
          17-valerate ester of 6{60 ,9{60 -difluorohydrocortisone, its compositions and use as an anti-inflammatory agent 
        | 
        
        
          | 
            
              DK135267A
              (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
            
            *
            
           | 
          1971-02-25 | 
           | 
           | 
           | 
        
        
          | 
            
              US3789121A
              (en)
            
            *
            
           | 
          1971-11-26 | 
          1974-01-29 | 
          Warner Lambert Co | 
          17{60 ,21-orthobutyrates of 6{60 , 9{60 -difluoro-hydrocortisone and 6{60 , 9{60 -difluoroprednisolone, compositions containing same and the use thereof as anti-inflammatory agents 
        | 
        
        
          | 
            
              GB1429184A
              (en)
            
            *
            
           | 
          1972-04-20 | 
          1976-03-24 | 
          Allen & Hanburys Ltd | 
          Physically anti-inflammatory steroids for use in aerosols 
      | 
        
        
          | 
            
              US4044126A
              (en)
            
            *
            
           | 
          1972-04-20 | 
          1977-08-23 | 
          Allen & Hanburys Limited | 
          Steroidal aerosol compositions and process for the preparation thereof 
        | 
        
        
          | 
            
              SE418294B
              (sv)
            
            *
            
           | 
          1974-03-27 | 
          1981-05-18 | 
          Plurichemie Anstalt | 
          Sett att framstella en 16alfa- eller 16beta-9alfa-klor eller -fluorsteroidester 
        | 
        
        
          | 
            
              US4018918A
              (en)
            
            *
            
           | 
          1975-05-20 | 
          1977-04-19 | 
          The Upjohn Company | 
          Topical clindamycin preparations 
        | 
        
        
          | 
            
              DE2645104C2
              (de)
            
            *
            
           | 
          1976-10-04 | 
          1986-04-24 | 
          Schering AG, 1000 Berlin und 4709 Bergkamen | 
          11β-Hydroxy-1,4,8-pregnatrien-3,20-dion-Derivate und Verfahren zu ihrer Herstellung 
        | 
        
        
          | 
            
              US4070462A
              (en)
            
            *
            
           | 
          1976-10-26 | 
          1978-01-24 | 
          Schering Corporation | 
          Steroid ointment 
        | 
        
        
          | 
            
              JPS6040439B2
              (ja)
            
            *
            
           | 
          1978-03-29 | 
          1985-09-11 | 
          大正製薬株式会社 | 
          ヒドロコルチゾン誘導体 
        | 
        
        
          | 
            
              EP0029151B1
              (en)
            
            *
            
           | 
          1979-11-16 | 
          1985-09-25 | 
          STEROSYNT Ltd. | 
          6-alpha-fluoro-9-alpha-chloro-prednisolone-17,21 diesters, pharmaceutical compositions containing them and intermediates 
        | 
        
        
          | 
            
              US4350690A
              (en)
            
            *
            
           | 
          1980-10-27 | 
          1982-09-21 | 
          Cressington Investments Ltd. | 
          Steroid composition 
        | 
        
        
          | 
            
              US4346086A
              (en)
            
            *
            
           | 
          1981-06-09 | 
          1982-08-24 | 
          Beiersdorf Aktiengesellschaft | 
          Corticosteroid-containing cream 
        | 
        
        
          | 
            
              IL66432A0
              (en)
            
            *
            
           | 
          1981-08-04 | 
          1982-12-31 | 
          Plurichemie Anstalt | 
          Process for the preparation of steroidal esters 
      | 
        
        
          | 
            
              DE3133081A1
              (de)
            
            *
            
           | 
          1981-08-18 | 
          1983-03-10 | 
          Schering Ag, 1000 Berlin Und 4619 Bergkamen | 
          Neue 6(alpha)-methylprednisolon-derivate, ihre herstellung und verwendung 
        | 
        
        
          | 
            
              FR2515041A1
              (fr)
            
            *
            
           | 
          1981-10-26 | 
          1983-04-29 | 
          Besins Jean | 
          Medicament a base de progesterone pour le traitement des affections mammaires 
        | 
        
        
          | 
            
              EP0095894A3
              (en)
            
            *
            
           | 
          1982-05-31 | 
          1985-01-02 | 
          Ohta Seiyaku Kabushiki Kaisha. | 
          6 alpha-methylprednisolone derivatives 
        | 
        
        
          | 
            
              DE3227312A1
              (de)
            
            *
            
           | 
          1982-07-19 | 
          1984-01-19 | 
          Schering AG, 1000 Berlin und 4709 Bergkamen | 
          Neue 6,16-dimethylkortikoide, ihre herstellung und verwendung 
        | 
        
        
          | 
            
              DE3243482A1
              (de)
            
            *
            
           | 
          1982-11-22 | 
          1984-05-24 | 
          Schering AG, 1000 Berlin und 4709 Bergkamen | 
          Neue 6(alpha)-methylkortikoide, ihre herstellung und verwendung 
        | 
        
        
          | 
            
              US4482539A
              (en)
            
            *
            
           | 
          1983-05-13 | 
          1984-11-13 | 
          Schering Corporation | 
          Betamethasone dipropionate cream 
        | 
        
        
          | 
            
              US4489070A
              (en)
            
            *
            
           | 
          1983-05-13 | 
          1984-12-18 | 
          Schering Corporation | 
          Betamethasone dipropionate cream 
        | 
        
        
          | 
            
              DE3400188A1
              (de)
            
            *
            
           | 
          1984-01-02 | 
          1985-07-11 | 
          Schering AG, Berlin und Bergkamen, 1000 Berlin | 
          Neue 6(alpha),16(alpha)-dimethylkortikoide 
        | 
        
        
          | 
            
              PT78973A
              (en)
            
            *
            
           | 
          1984-07-25 | 
          1984-08-01 | 
          Joao Emerico Villax | 
          New preparation process of the 9alpha-fluoro 17,21-acylates or hidroxilades in 17 and 21 chloro-corticosteroid 
      | 
        
        
          | 
            
              UA26230A
              (uk)
            
            *
            
           | 
          1990-03-02 | 
          1999-07-19 | 
          Глексо Груп Лімітед | 
          Іhгалятор для спільhого використаhhя з лікувальhим блоком і лікувальhий блок 
        | 
        
        
          | 
            
              US6536427B2
              (en)
            
            
            
           | 
          1990-03-02 | 
          2003-03-25 | 
          Glaxo Group Limited | 
          Inhalation device 
        | 
        
        
          | 
            
              SK280968B6
              (sk)
            
            
            
           | 
          1990-03-02 | 
          2000-10-09 | 
          Glaxo Group Limited | 
          Balenie medikamentu na použite v inhalačnom prístroji 
        | 
        
        
          | 
            
              US6777399B2
              (en)
            
            *
            
           | 
          2000-08-05 | 
          2004-08-17 | 
          Smithkline Beecham Corporation | 
          Anti-inflammatory androstane derivative compositions 
        | 
        
        
          | 
            
              US6858596B2
              (en)
            
            *
            
           | 
          2000-08-05 | 
          2005-02-22 | 
          Smithkline Beecham Corporation | 
          Formulation containing anti-inflammatory androstane derivative 
        | 
        
        
          | 
            
              CA2417825C
              (en)
            
            *
            
           | 
          2000-08-05 | 
          2008-07-22 | 
          Glaxo Group Limited | 
          6.alpha., 9.alpha.-difluoro-17.alpha.-`(2-furanylcarboxyl)oxy!-11.beta.-hydroxy-16.alpha.-methyl-3-oxo-androst-1,4,-diene-17-carbothioic acid s-fluoromethyl ester as an anti-inflammatory agent 
      | 
        
        
          | 
            
              US6759398B2
              (en)
            
            *
            
           | 
          2000-08-05 | 
          2004-07-06 | 
          Smithkline Beecham Corporation | 
          Anti-inflammatory androstane derivative 
        | 
        
        
          | 
            
              GB0019172D0
              (en)
            
            *
            
           | 
          2000-08-05 | 
          2000-09-27 | 
          Glaxo Group Ltd | 
          Novel compounds 
      | 
        
        
          | 
            
              MY137522A
              (en)
            
            *
            
           | 
          2001-04-30 | 
          2009-02-27 | 
          Glaxo Group Ltd | 
          Novel anti-inflammatory androstane derivatives. 
      | 
        
        
          | 
            
              WO2002100879A1
              (en)
            
            *
            
           | 
          2001-06-12 | 
          2002-12-19 | 
          Glaxo Group Limited | 
          Novel anti-inflammatory 17.alpha.-heterocyclic-esters of 17.beta.carbothioate androstane derivatives 
        | 
        
        
          | 
            
              WO2003048181A1
              (en)
            
            *
            
           | 
          2001-12-01 | 
          2003-06-12 | 
          Glaxo Group Limited | 
          17.alpha. -cyclic esters of 16-methylpregnan-3,20-dione as anti-inflammatory agents 
        | 
        
        
          | 
            
              US20050175545A1
              (en)
            
            *
            
           | 
          2002-02-04 | 
          2005-08-11 | 
          Keith Biggadike | 
          Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist 
        | 
        
        
          | 
            
              GB0202635D0
              (en)
            
            *
            
           | 
          2002-02-05 | 
          2002-03-20 | 
          Glaxo Wellcome Mfg Pte Ltd | 
          Formulation containing novel anti-inflammatory androstane derivative 
      | 
        
        
          | 
            
              GB2389530B
              (en)
            
            *
            
           | 
          2002-06-14 | 
          2007-01-10 | 
          Cipla Ltd | 
          Pharmaceutical compositions 
        | 
        
        
          | 
            
              CA2537185A1
              (en)
            
            *
            
           | 
          2003-08-29 | 
          2005-03-10 | 
          Ranbaxy Laboratories Limited | 
          Inhibitors of phosphodiesterase type-iv 
      | 
        
        
          | 
            
              EP1694655A2
              (en)
            
            *
            
           | 
          2003-11-26 | 
          2006-08-30 | 
          Ranbaxy Laboratories Limited | 
          Phosphodiesterase inhibitors 
        | 
        
        
          | 
            
              US20080009535A1
              (en)
            
            *
            
           | 
          2004-08-30 | 
          2008-01-10 | 
          Sarala Balachandran | 
          Inhibitors of phosphodiesterase type-IV 
        | 
        
        
          | 
            
              GB0507165D0
              (en)
            
            *
            
           | 
          2005-04-08 | 
          2005-05-18 | 
          Glaxo Group Ltd | 
          Novel crystalline pharmaceutical product 
      | 
        
        
          | 
            
              WO2007031838A1
              (en)
            
            
            
           | 
          2005-09-16 | 
          2007-03-22 | 
          Ranbaxy Laboratories Limited | 
          Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors 
        | 
        
        
          | 
            
              JP2009512676A
              (ja)
            
            
            
           | 
          2005-10-19 | 
          2009-03-26 | 
          ランバクシー  ラボラトリーズ  リミテッド | 
          ムスカリン性受容体アンタゴニストの医薬組成物 
        | 
        
        
          | 
            
              US20090054382A1
              (en)
            
            *
            
           | 
          2005-10-19 | 
          2009-02-26 | 
          Abhijit Ray | 
          Compositions of phosphodiesterase type iv inhibitors 
        | 
        
        
          | 
            
              GB0615108D0
              (en)
            
            *
            
           | 
          2006-07-28 | 
          2006-09-06 | 
          Glaxo Group Ltd | 
          Novel formulations 
      | 
        
        
          | 
            
              US20100029728A1
              (en)
            
            *
            
           | 
          2006-09-22 | 
          2010-02-04 | 
          Ranbaxy Laboratories Limited | 
          Phosphodiesterase inhibitors 
        | 
        
        
          | 
            
              AU2007298549A1
              (en)
            
            *
            
           | 
          2006-09-22 | 
          2008-03-27 | 
          Ranbaxy Laboratories Limited | 
          Inhibitors of phosphodiesterase type-IV 
      | 
        
        
          | 
            
              EP1958947A1
              (en)
            
            
            
           | 
          2007-02-15 | 
          2008-08-20 | 
          Ranbaxy Laboratories Limited | 
          Inhibitors of phosphodiesterase type 4 
        | 
        
        
          | 
            
              CN103497185A
              (zh)
            
            *
            
           | 
          2007-03-14 | 
          2014-01-08 | 
          兰贝克赛实验室有限公司 | 
          用作磷酸二酯酶抑制剂的吡唑并(3,4-b)吡啶衍生物 
        | 
        
        
          | 
            
              EP2124943A1
              (en)
            
            *
            
           | 
          2007-03-14 | 
          2009-12-02 | 
          Ranbaxy Laboratories Limited | 
          Pyrazolo [3, 4-b]pyridine derivatives as phosphodiesterase inhibitors 
        | 
        
        
          | 
            
              US8796248B2
              (en)
            
            
            
           | 
          2007-10-05 | 
          2014-08-05 | 
          Nektar Therapeutics | 
          Oligomer-corticosteroid conjugates 
        | 
        
        
          | 
            
              EP2111861A1
              (en)
            
            
            
           | 
          2008-04-21 | 
          2009-10-28 | 
          Ranbaxy Laboratories Limited | 
          Compositions of phosphodiesterase type IV inhibitors 
        | 
        
        
          | 
            
              CN112358522B
              (zh)
            
            *
            
           | 
          2020-05-18 | 
          2021-11-16 | 
          河南利华制药有限公司 | 
          一种倍他米松二丙酸酯的精制方法及倍他米松二丙酸酯 
        | 
        
        
          | 
            
              CN111944002A
              (zh)
            
            *
            
           | 
          2020-07-29 | 
          2020-11-17 | 
          河南利华制药有限公司 | 
          一种倍氯米松二丙酸酯中间体及制备方法 
        | 
        
        
          | 
            
              CN116023425B
              (zh)
            
            *
            
           | 
          2023-03-28 | 
          2023-06-20 | 
          南京师范大学 | 
          曲安西龙衍生物及其医药用途 
        |