CH450410A - Verfahren zur Herstellung von Steroiden der Pregnanreihe - Google Patents

Verfahren zur Herstellung von Steroiden der Pregnanreihe

Info

Publication number
CH450410A
CH450410A CH752364A CH752364A CH450410A CH 450410 A CH450410 A CH 450410A CH 752364 A CH752364 A CH 752364A CH 752364 A CH752364 A CH 752364A CH 450410 A CH450410 A CH 450410A
Authority
CH
Switzerland
Prior art keywords
pregnan
steroids
manufacture
range
pregnan range
Prior art date
Application number
CH752364A
Other languages
English (en)
Inventor
Elks Joseph
John May Peter
Galbraith Weir Niall
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of CH450410A publication Critical patent/CH450410A/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Insulated Conductors (AREA)
  • Combinations Of Kitchen Furniture (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CH752364A 1963-06-11 1964-06-09 Verfahren zur Herstellung von Steroiden der Pregnanreihe CH450410A (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB23223/63A GB1047518A (en) 1963-06-11 1963-06-11 17ª‡-monoesters of 11,17,21-trihydroxy steroid compounds
GB362364 1964-01-28

Publications (1)

Publication Number Publication Date
CH450410A true CH450410A (de) 1968-01-31

Family

ID=26238483

Family Applications (2)

Application Number Title Priority Date Filing Date
CH752364A CH450410A (de) 1963-06-11 1964-06-09 Verfahren zur Herstellung von Steroiden der Pregnanreihe
CH752464A CH457422A (de) 1963-06-11 1964-06-09 Verfahren zur Herstellung von Steroiden

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH752464A CH457422A (de) 1963-06-11 1964-06-09 Verfahren zur Herstellung von Steroiden

Country Status (14)

Country Link
US (1) US3312590A (de)
BE (2) BE649171A (de)
BR (2) BR6459936D0 (de)
CH (2) CH450410A (de)
CY (1) CY544A (de)
DE (2) DE1443957B1 (de)
DK (2) DK116205B (de)
ES (2) ES300814A1 (de)
FR (1) FR4548M (de)
GB (1) GB1047518A (de)
MY (1) MY7000131A (de)
NL (2) NL141378B (de)
NO (2) NO125532B (de)
SE (2) SE320066B (de)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
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US3475466A (en) * 1965-08-30 1969-10-28 Schering Corp Novel 17,21-diesters of 16alpha-methyl-9alpha,11beta-dichloro-1,4- pregnadienes
US3422193A (en) * 1966-08-11 1969-01-14 Schering Corp 17-mono esters of corticoids
IT1061787B (it) * 1967-03-01 1983-04-30 Vismara Francesco Spa Miglioramenti relativi alla preparazione di 17 benzoato di betametazone
GB1281689A (en) * 1968-10-14 1972-07-12 Glaxo Lab Ltd Steroid 21-phosphates
US3694471A (en) * 1970-06-08 1972-09-26 Warner Lambert Pharmaceutical 17-valerate ester of 6{60 ,9{60 -difluorohydrocortisone, its compositions and use as an anti-inflammatory agent
DK135267A (de) * 1971-02-25
US3789121A (en) * 1971-11-26 1974-01-29 Warner Lambert Co 17{60 ,21-orthobutyrates of 6{60 , 9{60 -difluoro-hydrocortisone and 6{60 , 9{60 -difluoroprednisolone, compositions containing same and the use thereof as anti-inflammatory agents
GB1429184A (en) * 1972-04-20 1976-03-24 Allen & Hanburys Ltd Physically anti-inflammatory steroids for use in aerosols
US4044126A (en) * 1972-04-20 1977-08-23 Allen & Hanburys Limited Steroidal aerosol compositions and process for the preparation thereof
SE418294B (sv) * 1974-03-27 1981-05-18 Plurichemie Anstalt Sett att framstella en 16alfa- eller 16beta-9alfa-klor eller -fluorsteroidester
US4018918A (en) * 1975-05-20 1977-04-19 The Upjohn Company Topical clindamycin preparations
DE2645104C2 (de) * 1976-10-04 1986-04-24 Schering AG, 1000 Berlin und 4709 Bergkamen 11β-Hydroxy-1,4,8-pregnatrien-3,20-dion-Derivate und Verfahren zu ihrer Herstellung
US4070462A (en) * 1976-10-26 1978-01-24 Schering Corporation Steroid ointment
JPS6040439B2 (ja) * 1978-03-29 1985-09-11 大正製薬株式会社 ヒドロコルチゾン誘導体
DE3069074D1 (en) * 1979-11-16 1984-10-04 Sterosynt Ltd 6-alpha-9-alpha-difluoro-16-beta-methyl-prednisolone-17,21 diesters and pharmaceutical compositions containing them
US4350690A (en) * 1980-10-27 1982-09-21 Cressington Investments Ltd. Steroid composition
US4346086A (en) * 1981-06-09 1982-08-24 Beiersdorf Aktiengesellschaft Corticosteroid-containing cream
IL66432A0 (en) * 1981-08-04 1982-12-31 Plurichemie Anstalt Process for the preparation of steroidal esters
DE3133081A1 (de) * 1981-08-18 1983-03-10 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue 6(alpha)-methylprednisolon-derivate, ihre herstellung und verwendung
FR2515041A1 (fr) * 1981-10-26 1983-04-29 Besins Jean Medicament a base de progesterone pour le traitement des affections mammaires
EP0095894A3 (de) * 1982-05-31 1985-01-02 Ohta Seiyaku Kabushiki Kaisha. 6-Alpha Methyl Prednisolon Derivate
DE3227312A1 (de) * 1982-07-19 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6,16-dimethylkortikoide, ihre herstellung und verwendung
DE3243482A1 (de) * 1982-11-22 1984-05-24 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6(alpha)-methylkortikoide, ihre herstellung und verwendung
US4482539A (en) * 1983-05-13 1984-11-13 Schering Corporation Betamethasone dipropionate cream
US4489070A (en) * 1983-05-13 1984-12-18 Schering Corporation Betamethasone dipropionate cream
DE3400188A1 (de) * 1984-01-02 1985-07-11 Schering AG, Berlin und Bergkamen, 1000 Berlin Neue 6(alpha),16(alpha)-dimethylkortikoide
PT78973A (en) * 1984-07-25 1984-08-01 Joao Emerico Villax New preparation process of the 9alpha-fluoro 17,21-acylates or hidroxilades in 17 and 21 chloro-corticosteroid
UA26230A (uk) * 1990-03-02 1999-07-19 Глексо Груп Лімітед Іhгалятор для спільhого використаhhя з лікувальhим блоком і лікувальhий блок
HU213221B (en) 1990-03-02 1997-03-28 Glaxo Group Ltd Inhalation device and medicine packet for device
US6536427B2 (en) 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
US6759398B2 (en) * 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
NZ523958A (en) * 2000-08-05 2004-11-26 Glaxo Group Ltd 17.beta.-carbothioate 17.alpha.-arylcarbonyloxyloxy androstane derviative as anti-inflammatory agents
GB0019172D0 (en) * 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6777399B2 (en) * 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6858596B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
MY137522A (en) * 2001-04-30 2009-02-27 Glaxo Group Ltd Novel anti-inflammatory androstane derivatives.
ES2307751T3 (es) * 2001-06-12 2008-12-01 Glaxo Group Limited Nuevos esteres heterociclicos centi-inflamatorios 17 alfa de derivados 17 beta de carbotioato de androstano.
AU2002356759A1 (en) * 2001-12-01 2003-06-17 Glaxo Group Limited 17.alpha. -cyclic esters of 16-methylpregnan-3,20-dione as anti-inflammatory agents
US20050175545A1 (en) * 2002-02-04 2005-08-11 Keith Biggadike Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) * 2002-02-05 2002-03-20 Glaxo Wellcome Mfg Pte Ltd Formulation containing novel anti-inflammatory androstane derivative
GB2389530B (en) * 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
BRPI0413330A (pt) * 2003-08-29 2006-10-10 Ranbaxy Lab Ltd inibidores de fosfodiesterase do tipo iv, composição farmacêutica contendo os mesmos e processo para sua preparação
WO2005051931A2 (en) * 2003-11-26 2005-06-09 Ranbaxy Laboratories Limited Phosphodiesterase inhibitors
US20080009535A1 (en) * 2004-08-30 2008-01-10 Sarala Balachandran Inhibitors of phosphodiesterase type-IV
GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
EP1934219A1 (de) 2005-09-16 2008-06-25 Ranbaxy Laboratories Limited Substituierte pyrazolo-[3,4-b]-pyridine als phosphodiesterase-inhibitoren
JP2009512677A (ja) * 2005-10-19 2009-03-26 ランバクシー ラボラトリーズ リミテッド ホスホジエステラーゼタイプｉｖ阻害剤の組成物
AU2006305619A1 (en) 2005-10-19 2007-04-26 Ranbaxy Laboratories Limited Pharmaceutical compositions of muscarinic receptor antagonists
GB0615108D0 (en) * 2006-07-28 2006-09-06 Glaxo Group Ltd Novel formulations
CN101616901A (zh) * 2006-09-22 2009-12-30 兰贝克赛实验室有限公司 Iv型磷酸二酯酶的抑制剂
WO2008035316A2 (en) * 2006-09-22 2008-03-27 Ranbaxy Laboratories Limited Phosphodiesterase inhibitors
US20080207659A1 (en) * 2007-02-15 2008-08-28 Asit Kumar Chakraborti Inhibitors of phosphodiesterase type 4
CN103497185A (zh) * 2007-03-14 2014-01-08 兰贝克赛实验室有限公司 用作磷酸二酯酶抑制剂的吡唑并(3,4-b)吡啶衍生物
EP2124943A1 (de) * 2007-03-14 2009-12-02 Ranbaxy Laboratories Limited Pyrazolo[3,4-b]pyridinderivate als phosphodiesterasehemmer
US8796248B2 (en) * 2007-10-05 2014-08-05 Nektar Therapeutics Oligomer-corticosteroid conjugates
EP2111861A1 (de) 2008-04-21 2009-10-28 Ranbaxy Laboratories Limited Zusammensetzungen von Phosphodiesterase-IV-Hemmern
CN112358522B (zh) * 2020-05-18 2021-11-16 河南利华制药有限公司 一种倍他米松二丙酸酯的精制方法及倍他米松二丙酸酯
CN111944002A (zh) * 2020-07-29 2020-11-17 河南利华制药有限公司 一种倍氯米松二丙酸酯中间体及制备方法
CN116023425B (zh) * 2023-03-28 2023-06-20 南京师范大学 曲安西龙衍生物及其医药用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3147249A (en) * 1961-06-13 1964-09-01 Vismara Francesco Spa 17alpha, 21-substituted methylenedioxy steroids and methods therefor
DE1195748B (de) * 1961-06-24 1965-07-01 Vismara Francesco Spa Verfahren zur Herstellung von 1'-substituierten 17alpha, 21-(1'-Alkoxy)-methylendioxysterioden

Also Published As

Publication number Publication date
SE313562B (de) 1969-08-18
DK116205B (da) 1969-12-22
DE1443957B1 (de) 1970-01-02
US3312590A (en) 1967-04-04
NL142157B (nl) 1974-05-15
FR4548M (de) 1966-11-02
NL6406615A (de) 1964-12-14
NO125532B (de) 1972-09-25
CH457422A (de) 1968-06-15
BE649171A (de) 1964-12-11
SE320066B (de) 1970-02-02
GB1047518A (en) 1966-11-02
ES300811A1 (es) 1962-12-16
DK116128B (da) 1969-12-15
BR6459936D0 (pt) 1973-08-02
NL141378B (nl) 1974-03-15
BR6459937D0 (pt) 1973-08-07
NO125533B (de) 1972-09-25
CY544A (en) 1970-07-02
BE649170A (de) 1964-12-11
NL6406614A (de) 1964-12-14
DE1443958B1 (de) 1970-01-02
ES300814A1 (es) 1964-12-01
MY7000131A (en) 1970-12-31

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