NL194637C - Werkwijze voor het vervaardigen van deeltjes, bedoeld voor het over een verloop van tijd afgeven van een effectieve hoeveelheid actief bestanddeel. - Google Patents

Werkwijze voor het vervaardigen van deeltjes, bedoeld voor het over een verloop van tijd afgeven van een effectieve hoeveelheid actief bestanddeel. Download PDF

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Publication number
NL194637C
NL194637C NL9101306A NL9101306A NL194637C NL 194637 C NL194637 C NL 194637C NL 9101306 A NL9101306 A NL 9101306A NL 9101306 A NL9101306 A NL 9101306A NL 194637 C NL194637 C NL 194637C
Authority
NL
Netherlands
Prior art keywords
gel
particles
mpa
temperature
lactide
Prior art date
Application number
NL9101306A
Other languages
English (en)
Dutch (nl)
Other versions
NL9101306A (nl
NL194637B (nl
Inventor
Jean-Marc Ruiz
Original Assignee
Sociutu De Conseils De Rech S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sociutu De Conseils De Rech S filed Critical Sociutu De Conseils De Rech S
Publication of NL9101306A publication Critical patent/NL9101306A/nl
Publication of NL194637B publication Critical patent/NL194637B/xx
Application granted granted Critical
Publication of NL194637C publication Critical patent/NL194637C/nl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Glanulating (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NL9101306A 1990-08-01 1991-07-30 Werkwijze voor het vervaardigen van deeltjes, bedoeld voor het over een verloop van tijd afgeven van een effectieve hoeveelheid actief bestanddeel. NL194637C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9016885 1990-08-01
GB909016885A GB9016885D0 (en) 1990-08-01 1990-08-01 Sustained release pharmaceutical compositions

Publications (3)

Publication Number Publication Date
NL9101306A NL9101306A (nl) 1992-03-02
NL194637B NL194637B (nl) 2002-06-03
NL194637C true NL194637C (nl) 2002-10-04

Family

ID=10679993

Family Applications (1)

Application Number Title Priority Date Filing Date
NL9101306A NL194637C (nl) 1990-08-01 1991-07-30 Werkwijze voor het vervaardigen van deeltjes, bedoeld voor het over een verloop van tijd afgeven van een effectieve hoeveelheid actief bestanddeel.

Country Status (30)

Country Link
US (1) US5213812A (cs)
JP (1) JP2818704B2 (cs)
KR (1) KR920003962A (cs)
AT (1) AT396425B (cs)
AU (2) AU649696B2 (cs)
BE (1) BE1004772A3 (cs)
CA (1) CA2048270C (cs)
CH (1) CH682715A5 (cs)
DE (1) DE4125542A1 (cs)
DK (1) DK175756B1 (cs)
ES (1) ES2046083B1 (cs)
FI (1) FI104149B1 (cs)
FR (1) FR2665360B1 (cs)
GB (1) GB9016885D0 (cs)
GR (1) GR1001512B (cs)
HK (1) HK33294A (cs)
IE (1) IE65124B1 (cs)
IN (1) IN178446B (cs)
IT (1) IT1251788B (cs)
LU (1) LU87982A1 (cs)
MA (1) MA22245A1 (cs)
MY (1) MY107500A (cs)
NL (1) NL194637C (cs)
NO (1) NO300158B1 (cs)
NZ (1) NZ238981A (cs)
OA (1) OA09387A (cs)
PT (1) PT98497B (cs)
SE (1) SE505734C2 (cs)
TN (1) TNSN91067A1 (cs)
ZA (1) ZA915565B (cs)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US5569467A (en) * 1993-05-15 1996-10-29 Societe De Conseils De Recherches Et D'applications (S.C.R.A.S.) Process for the preparation of microballs and microballs thus obtained
GB9310030D0 (en) * 1993-05-15 1993-06-30 Scras Dry processed particles and process for the preparation of the same
JP2930421B2 (ja) * 1994-02-28 1999-08-03 メディノヴァ メディカル コンサルティング ゲゼルシャフト ミット ベシュレンクテル ハフツング 薬剤組成物、その製造方法及びその使用方法
US5980945A (en) * 1996-01-16 1999-11-09 Societe De Conseils De Recherches Et D'applications Scientifique S.A. Sustained release drug formulations
DE19604744A1 (de) 1996-02-09 1997-08-14 Henkel Kgaa Technische Di-/Triglyceridgemische
DE19617137C1 (de) * 1996-04-29 1997-02-27 Henkel Kgaa Verwendung von Copolymerestern für die Herstellung von Mikrosphären
AU4571097A (en) * 1996-10-09 1998-05-05 Takeda Chemical Industries Ltd. A method for producing a microparticle
AR012448A1 (es) * 1997-04-18 2000-10-18 Ipsen Pharma Biotech Composicion en forma de microcapsulas o de implantes que comprende un excipiente biodegradable, polimero o co-polimero, o una mezcla de talesexcipientes, y una sustancia activa o una mezcla de sustancias activas, procedimiento para la preparacion de una sustancia soluble en agua de elevada
EP1079967A4 (en) 1998-04-13 2003-07-23 Luminex Corp LIQUID MARKING USING FLUORESCENT MICROPARTICLES
AU770673B2 (en) * 1998-12-16 2004-02-26 Aventisub Ii Inc. Biodegradable polymer encapsulated serotonin receptor antagonist and method for preparing the same
AU5644400A (en) * 1999-09-24 2001-03-29 Rohm And Haas Company Pellet compositions
US6458387B1 (en) * 1999-10-18 2002-10-01 Epic Therapeutics, Inc. Sustained release microspheres
ES2326209T3 (es) 2000-10-27 2009-10-05 Baxter Healthcare S.A. Produccion de microesferas.
PT1418890E (pt) * 2001-08-16 2008-06-09 Baxter Int Formulações de micropartículas à base de propulsor
US20080026068A1 (en) * 2001-08-16 2008-01-31 Baxter Healthcare S.A. Pulmonary delivery of spherical insulin microparticles
US20040166077A1 (en) * 2002-12-04 2004-08-26 L'oreal Process for treating keratin materials with aromatic active principles
FR2848113B1 (fr) * 2002-12-04 2005-02-25 Oreal Stabilisation de principes actifs aromatiques par des polymeres aromatiques
WO2005035088A2 (en) * 2003-07-18 2005-04-21 Baxter International, Inc. Method for preparing small spherical by controlled phase separation
US20050142205A1 (en) * 2003-07-18 2005-06-30 Julia Rashba-Step Methods for encapsulating small spherical particles prepared by controlled phase separation
US20070092452A1 (en) * 2003-07-18 2007-04-26 Julia Rashba-Step Methods for fabrication, uses, compositions of inhalable spherical particles
EP1646354A4 (en) * 2003-07-22 2010-03-17 Baxter Int SMALL SPHERICAL PARTICLES OF LOW MOLECULAR WEIGHT MOLECULES AND PROCESSES FOR THEIR PREPARATION AND USE
US20060135277A1 (en) * 2003-09-10 2006-06-22 Marnocha Bendict F Golf club and practice arrangement
FR2865938B1 (fr) * 2004-02-05 2006-06-02 Sod Conseils Rech Applic Formulation retard solide comprenant de l'acetate de triptoreline
US8728525B2 (en) * 2004-05-12 2014-05-20 Baxter International Inc. Protein microspheres retaining pharmacokinetic and pharmacodynamic properties
AU2005244840C1 (en) * 2004-05-12 2012-05-10 Baxter Healthcare S.A. Microspheres comprising protein and showing injectability at high concentrations of said agent
EP2335689A1 (en) 2004-05-12 2011-06-22 Baxter International Inc. Method of manufacturing nucleic acid micropheres
US7884085B2 (en) * 2004-05-12 2011-02-08 Baxter International Inc. Delivery of AS-oligonucleotide microspheres to induce dendritic cell tolerance for the treatment of autoimmune type 1 diabetes
KR20070042176A (ko) * 2004-07-13 2007-04-20 알타이어나노 인코포레이티드 약물 전용의 방지를 위한 세라믹 구조체
CN101010051A (zh) * 2004-07-13 2007-08-01 爱尔达纳米公司 用于控释药物的陶瓷结构
US20070243234A1 (en) * 2004-10-29 2007-10-18 Peter Gabriele Microscopic Tagging System for Security Identification
US20060260777A1 (en) * 2005-04-27 2006-11-23 Julia Rashba-Step Surface-modified microparticles and methods of forming and using the same
EP1928814A2 (en) * 2005-08-23 2008-06-11 Altairnano, Inc HIGHLY PHOTOCATALYTIC PHOSPHORUS-DOPED ANATASE-TiO2 COMPOSITION AND RELATED MANUFACTURING METHODS
WO2007103829A1 (en) * 2006-03-02 2007-09-13 Altairnano, Inc. Method for production of metal oxide coatings
US20080038482A1 (en) * 2006-03-02 2008-02-14 Fred Ratel Method for Low Temperature Production of Nano-Structured Iron Oxide Coatings
US20080020175A1 (en) * 2006-03-02 2008-01-24 Fred Ratel Nanostructured Indium-Doped Iron Oxide
US20070281031A1 (en) * 2006-06-01 2007-12-06 Guohan Yang Microparticles and methods for production thereof
MX2009001226A (es) * 2006-08-04 2009-03-20 Baxter Int Composicion basada en microesferas para prevenir y/o revertir la diabetes autoinmune de nuevo inicio.
EP2068845A2 (en) * 2006-10-06 2009-06-17 Baxter International Inc. Microencapsules containing surface-modified microparticles and methods of forming and using the same
CA2702340C (en) 2006-10-12 2014-12-16 The University Of Queensland Compositions and methods for modulating immune responses
US20090169628A1 (en) * 2006-10-17 2009-07-02 Armark Authentication Technologies, Llc Article and method for focused delivery of therapeutic and/or diagnostic materials
US20080254258A1 (en) * 2007-04-12 2008-10-16 Altairnano, Inc. Teflon® replacements and related production methods
CN101686939B (zh) * 2007-04-17 2013-03-27 巴克斯特国际公司 用于肺部投送的核酸微粒
US9782300B2 (en) 2008-02-01 2017-10-10 Kci Licensing, Inc. Fiber-microsphere bioresorbable composite scaffold for wound healing
PL2281042T3 (pl) 2008-04-18 2016-01-29 Baxter Int Kompozycja na bazie mikrosfer do zapobiegania i/lub cofania nowego przypadku cukrzycy autoimmunologicznej
US8323615B2 (en) * 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing multi-phasic dispersions
US20100047292A1 (en) * 2008-08-20 2010-02-25 Baxter International Inc. Methods of processing microparticles and compositions produced thereby
US8367427B2 (en) * 2008-08-20 2013-02-05 Baxter International Inc. Methods of processing compositions containing microparticles
US8323685B2 (en) * 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing compositions containing microparticles
US20100078848A1 (en) * 2008-09-29 2010-04-01 Armark Authentication Technologies, Llc Spinneret and method of spinning fiber
US20100291214A1 (en) * 2008-12-23 2010-11-18 Armark Authentication Technologies, Llc Three-dimensional microfiber extrudate structure and process for forming three-dimensional microfiber extrudate structure
WO2010132763A1 (en) * 2009-05-15 2010-11-18 Armark Authentication Technologies, Llc Fiber having non-uniform composition and method for making same
CA2762647A1 (en) * 2009-05-27 2010-12-02 Selecta Biosciences, Inc. Nanocarriers possessing components with different rates of release
US20110076771A1 (en) * 2009-09-25 2011-03-31 Armark Authentication Technologies, Llc Tissue fiber scaffold and method for making
US20110293701A1 (en) 2010-05-26 2011-12-01 Selecta Biosciences, Inc. Multivalent synthetic nanocarrier vaccines
EP2399931A1 (fr) * 2010-06-22 2011-12-28 Ipsen Pharma S.A.S. Nouveaux composés octapeptidiques et leur utilisation thérapeutique
DK2635596T3 (da) 2010-11-01 2019-11-25 Univ Sydney Technology Immun-moduleringsmidler og anvendelser dertil
US20130028857A1 (en) 2011-07-29 2013-01-31 Selecta Biosciences, Inc. Synthetic nanocarriers comprising polymers comprising multiple immunomodulatory agents
DK3149049T3 (da) 2014-05-27 2023-01-23 Univ Queensland Il-22 til anvendelse til behandling af stofskiftesygdomme
FR3067226B1 (fr) * 2017-06-13 2021-10-08 Rossignol Lange Element de chaussure de ski

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3567650A (en) * 1969-02-14 1971-03-02 Ncr Co Method of making microscopic capsules
US4010125A (en) * 1975-06-12 1977-03-01 Schally Andrew Victor [D-Trp6 ]-LH-RH and intermediates therefor
US4675189A (en) * 1980-11-18 1987-06-23 Syntex (U.S.A.) Inc. Microencapsulation of water soluble active polypeptides
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
JPS60100516A (ja) * 1983-11-04 1985-06-04 Takeda Chem Ind Ltd 徐放型マイクロカプセルの製造法
IN167096B (cs) * 1985-04-04 1990-09-01 Akzo Nv
US4666705A (en) * 1985-06-03 1987-05-19 E. R. Squibb & Sons, Inc. Controlled release formulation
GB8628728D0 (en) * 1986-12-02 1987-01-07 Euro Celtique Sa Spheroids
GB8705083D0 (en) * 1987-03-04 1987-04-08 Euro Celtique Sa Spheroids
AU4369589A (en) * 1988-10-27 1990-05-03 Abbott Laboratories Controlled-release delivery device, method for producing device, and method of using device

Also Published As

Publication number Publication date
OA09387A (fr) 1992-09-15
FI913646L (fi) 1992-02-02
FI104149B (fi) 1999-11-30
FR2665360B1 (fr) 1995-02-10
AU666808B2 (en) 1996-02-22
CA2048270A1 (en) 1992-02-02
ES2046083A1 (es) 1994-01-16
SE9102249L (sv) 1992-02-02
US5213812A (en) 1993-05-25
LU87982A1 (fr) 1992-04-15
FI104149B1 (fi) 1999-11-30
AU8146691A (en) 1992-02-06
PT98497A (pt) 1992-06-30
NL9101306A (nl) 1992-03-02
IT1251788B (it) 1995-05-26
SE9102249D0 (sv) 1991-07-26
DK141891D0 (da) 1991-07-31
DK141891A (da) 1992-02-02
AU649696B2 (en) 1994-06-02
JPH05178740A (ja) 1993-07-20
AT396425B (de) 1993-09-27
DE4125542A1 (de) 1992-02-06
TNSN91067A1 (fr) 1992-10-25
ITMI911953A0 (it) 1991-07-15
DK175756B1 (da) 2005-02-14
FR2665360A1 (fr) 1992-02-07
KR920003962A (ko) 1992-03-27
JP2818704B2 (ja) 1998-10-30
GB9016885D0 (en) 1990-09-12
PT98497B (pt) 1997-10-31
GR910100330A (en) 1992-08-31
ITMI911953A1 (it) 1993-01-15
HK33294A (en) 1994-04-22
ZA915565B (en) 1992-04-29
IE65124B1 (en) 1995-10-04
CA2048270C (en) 1997-02-25
ES2046083B1 (es) 1994-08-01
ATA152591A (de) 1993-01-15
IE912700A1 (en) 1992-02-12
GR1001512B (el) 1994-02-28
NO912986D0 (no) 1991-07-31
FI913646A0 (fi) 1991-07-31
IN178446B (cs) 1997-05-03
MY107500A (en) 1995-12-30
AU5939394A (en) 1994-06-02
CH682715A5 (fr) 1993-11-15
NO300158B1 (no) 1997-04-21
NL194637B (nl) 2002-06-03
NO912986L (no) 1992-02-03
SE505734C2 (sv) 1997-10-06
NZ238981A (en) 1992-11-25
MA22245A1 (fr) 1992-04-01
BE1004772A3 (fr) 1993-01-26

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Effective date: 20110201