NL187854B - Werkwijze ter bereiding van farmaceutische preparaten met diuretische en saluretische werking, alsmede werkwijze ter bereiding van voor toepassing daarbij geschikte op plaats 2 gesubstitueerde 1-oxo-5-indanyloxy-(of -thio-)-alkaanzuren. - Google Patents

Werkwijze ter bereiding van farmaceutische preparaten met diuretische en saluretische werking, alsmede werkwijze ter bereiding van voor toepassing daarbij geschikte op plaats 2 gesubstitueerde 1-oxo-5-indanyloxy-(of -thio-)-alkaanzuren.

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Publication number
NL187854B
NL187854B NLAANVRAGE7412829,A NL7412829A NL187854B NL 187854 B NL187854 B NL 187854B NL 7412829 A NL7412829 A NL 7412829A NL 187854 B NL187854 B NL 187854B
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Prior art keywords
indanyloxyles
acious
diuretic
thio
substitutes
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Application number
NLAANVRAGE7412829,A
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English (en)
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NL7412829A (nl
NL187854C (nl
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Merck & Co Inc
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Publication of NL7412829A publication Critical patent/NL7412829A/nl
Publication of NL187854B publication Critical patent/NL187854B/nl
Application granted granted Critical
Publication of NL187854C publication Critical patent/NL187854C/nl

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    • C07D257/04—Five-membered rings
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    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/33—Polycyclic acids
    • C07C63/337—Polycyclic acids with carboxyl groups bound to condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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  • Diabetes (AREA)
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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
NLAANVRAGE7412829,A 1973-10-11 1974-09-27 Werkwijze ter bereiding van farmaceutische preparaten met diuretische en saluretische werking, alsmede werkwijze ter bereiding van voor toepassing daarbij geschikte op plaats 2 gesubstitueerde 1-oxo-5-indanyloxy-(of -thio-)-alkaanzuren. NL187854C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40573673A 1973-10-11 1973-10-11
US49265174A 1974-07-30 1974-07-30

Publications (3)

Publication Number Publication Date
NL7412829A NL7412829A (nl) 1975-04-15
NL187854B true NL187854B (nl) 1991-09-02
NL187854C NL187854C (nl) 1992-02-03

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Application Number Title Priority Date Filing Date
NLAANVRAGE7412829,A NL187854C (nl) 1973-10-11 1974-09-27 Werkwijze ter bereiding van farmaceutische preparaten met diuretische en saluretische werking, alsmede werkwijze ter bereiding van voor toepassing daarbij geschikte op plaats 2 gesubstitueerde 1-oxo-5-indanyloxy-(of -thio-)-alkaanzuren.
NL9100396A NL9100396A (nl) 1973-10-11 1991-03-05 Werkwijze ter bereiding van farmaceutische preparaten met diuretische en uricosurische werking, alsmede werkwijze ter bereiding van voor toepassing daarbij geschikte, op plaats 2 van de indaanrest gesubstitueerde 5-(1-oxo-5-indanyloxy- (of -thio-)methyl)tetrazolen.

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NL9100396A NL9100396A (nl) 1973-10-11 1991-03-05 Werkwijze ter bereiding van farmaceutische preparaten met diuretische en uricosurische werking, alsmede werkwijze ter bereiding van voor toepassing daarbij geschikte, op plaats 2 van de indaanrest gesubstitueerde 5-(1-oxo-5-indanyloxy- (of -thio-)methyl)tetrazolen.

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JP (1) JPS5939415B2 (nl)
KR (1) KR870000034B1 (nl)
AR (4) AR213065A1 (nl)
AT (1) AT342036B (nl)
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CA (1) CA1063125A (nl)
CH (2) CH613933A5 (nl)
CS (1) CS190439B2 (nl)
CY (1) CY1074A (nl)
DD (1) DD118075A5 (nl)
DE (2) DE2463215C2 (nl)
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ES (2) ES430900A1 (nl)
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GB (2) GB1474460A (nl)
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NL (2) NL187854C (nl)
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IE51535B1 (en) * 1980-09-02 1987-01-07 Merck & Co Inc Pharmaceutical compositions containing 4-((6,7-dihalogen-2,3-dihydro-1-oxo-1h-inden-5-yl)-oxy)butanoic acid compounds
US5489712A (en) * 1994-11-04 1996-02-06 Hoechst Celanese Corporation Process for preparing cyclic ketones
CN109748785A (zh) * 2019-01-14 2019-05-14 山东大学 一种二芳香烃取代丙烯酮类化合物及制备方法与应用

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US3704314A (en) * 1968-11-25 1972-11-28 Merck & Co Inc (1-oxo-2-alkylideneindanyloxy) and (1-oxo - 2 - alkylideneindanylthio) alkanoic acids
US3668241A (en) * 1968-11-25 1972-06-06 Merck & Co Inc Substituted 1-oxoinden-5-yloxy alkanoic acids

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IE39927L (en) 1975-04-11
PH22017A (en) 1988-05-13
ES449917A1 (es) 1977-11-16
JPS5939415B2 (ja) 1984-09-22
HK47680A (en) 1980-09-05
YU39727B (en) 1985-04-30
KR830000198A (ko) 1983-03-30
KE3068A (en) 1980-08-08
ES430900A1 (es) 1977-01-01
RO64568A (fr) 1979-03-15
PH22225A (en) 1988-07-01
JPS5076058A (nl) 1975-06-21
LU71078A1 (nl) 1975-06-24
FR2247218B1 (nl) 1978-02-03
AR213620A1 (es) 1979-02-28
KR870000034B1 (ko) 1987-02-07
ATA807874A (de) 1977-07-15
AT342036B (de) 1978-03-10
IL45779A0 (en) 1974-12-31
AR213170A1 (es) 1978-12-29
NL7412829A (nl) 1975-04-15
RO71480B (ro) 1983-07-30
AR213840A1 (es) 1979-03-30
AR213065A1 (es) 1978-12-15
DE2448454C2 (de) 1985-08-29
GB1474460A (en) 1977-05-25
CH613933A5 (en) 1979-10-31
SU738509A3 (ru) 1980-05-30
DE2463215C2 (de) 1986-03-13
GB1474459A (en) 1977-05-25
NL187854C (nl) 1992-02-03
AU7391674A (en) 1976-04-08
BG28255A3 (en) 1980-03-25
CH610290A5 (en) 1979-04-12
FR2247218A1 (nl) 1975-05-09
IE39927B1 (en) 1979-01-31
EG11741A (en) 1977-12-31
DE2448454A1 (de) 1975-04-24
HU169587B (nl) 1976-12-28
MY8100163A (en) 1981-12-31
CA1063125A (en) 1979-09-25
YU272774A (en) 1983-06-30
NL9100396A (nl) 1991-06-03
DD118075A5 (nl) 1976-02-12
IL45779A (en) 1978-06-15
RO71480A (ro) 1983-08-03
CS190439B2 (en) 1979-05-31
CY1074A (en) 1980-10-24

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