NL182963C - Werkwijze voor de bereiding van een 11beta-hydroxy-16-methyl-17alfa-acyloxycorticosteroide door solvolyse van de overeenkomstige 11-trifluoracetoxyverbinding. - Google Patents
Werkwijze voor de bereiding van een 11beta-hydroxy-16-methyl-17alfa-acyloxycorticosteroide door solvolyse van de overeenkomstige 11-trifluoracetoxyverbinding.Info
- Publication number
- NL182963C NL182963C NLAANVRAGE8102602,A NL8102602A NL182963C NL 182963 C NL182963 C NL 182963C NL 8102602 A NL8102602 A NL 8102602A NL 182963 C NL182963 C NL 182963C
- Authority
- NL
- Netherlands
- Prior art keywords
- acyloxycorticosteroid
- trifluoracetoxy
- solvolysis
- alfa
- beta
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
- C07J7/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16
- C07J7/0055—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT71309A PT71309A (en) | 1980-05-27 | 1980-05-27 | Process of selective |
| PT7130980 | 1980-05-27 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NL8102602A NL8102602A (nl) | 1981-12-16 |
| NL182963B NL182963B (nl) | 1988-01-18 |
| NL182963C true NL182963C (nl) | 1988-06-16 |
Family
ID=20082722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NLAANVRAGE8102602,A NL182963C (nl) | 1980-05-27 | 1981-05-27 | Werkwijze voor de bereiding van een 11beta-hydroxy-16-methyl-17alfa-acyloxycorticosteroide door solvolyse van de overeenkomstige 11-trifluoracetoxyverbinding. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4343739A (ko) |
| JP (1) | JPS5767598A (ko) |
| KR (1) | KR840001809B1 (ko) |
| CH (1) | CH655320A5 (ko) |
| GB (1) | GB2079754B (ko) |
| HK (1) | HK52186A (ko) |
| IL (1) | IL62948A (ko) |
| NL (1) | NL182963C (ko) |
| PT (1) | PT71309A (ko) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2510582B1 (fr) | 1981-07-30 | 1986-05-30 | Sipsy | Steroides esterifies en la position 17 et thio-esterifies en la position 21, leur procede de preparation et leur application comme medicament |
| IL66432A0 (en) * | 1981-08-04 | 1982-12-31 | Plurichemie Anstalt | Process for the preparation of steroidal esters |
| KR890000664B1 (ko) * | 1981-10-19 | 1989-03-22 | 바리 안소니 뉴우샘 | 미분된 베클로메타손 디프로피오네이트 일수화물의 제조방법 |
| DE19741874A1 (de) | 1997-09-23 | 1999-04-01 | Henkel Ecolab Gmbh & Co Ohg | Alkoholathaltiger Reiniger |
| FR2800635B1 (fr) * | 1999-11-05 | 2002-07-26 | Bio Merieux | Nanospheres composites, conjugues derives, procede de preparation et leurs utilisations |
| CN105646630A (zh) * | 2015-08-10 | 2016-06-08 | 山东泰华生物科技有限公司 | 一锅法制备丙酸氯倍他索中间体 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2512915A1 (de) * | 1974-03-27 | 1975-10-09 | Plurichemie Anstalt | 16-methyl-9 alpha-halogen-steroide ester, aether und verfahren zu ihrer herstellung |
| JPS50157357A (ko) * | 1974-06-10 | 1975-12-19 |
-
1980
- 1980-05-27 PT PT71309A patent/PT71309A/pt unknown
-
1981
- 1981-05-19 GB GB8115317A patent/GB2079754B/en not_active Expired
- 1981-05-25 IL IL62948A patent/IL62948A/xx unknown
- 1981-05-26 CH CH3452/81A patent/CH655320A5/de not_active IP Right Cessation
- 1981-05-26 JP JP56078794A patent/JPS5767598A/ja active Granted
- 1981-05-27 KR KR1019810001857A patent/KR840001809B1/ko active
- 1981-05-27 US US06/267,553 patent/US4343739A/en not_active Expired - Fee Related
- 1981-05-27 NL NLAANVRAGE8102602,A patent/NL182963C/xx not_active IP Right Cessation
-
1986
- 1986-07-10 HK HK521/86A patent/HK52186A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US4343739A (en) | 1982-08-10 |
| GB2079754A (en) | 1982-01-27 |
| HK52186A (en) | 1986-07-18 |
| NL182963B (nl) | 1988-01-18 |
| CH655320A5 (de) | 1986-04-15 |
| JPS6411038B2 (ko) | 1989-02-23 |
| JPS5767598A (en) | 1982-04-24 |
| NL8102602A (nl) | 1981-12-16 |
| KR830006328A (ko) | 1983-09-24 |
| IL62948A (en) | 1984-08-31 |
| PT71309A (en) | 1980-06-01 |
| KR840001809B1 (ko) | 1984-10-20 |
| GB2079754B (en) | 1984-11-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1A | A request for search or an international-type search has been filed | ||
| BB | A search report has been drawn up | ||
| BC | A request for examination has been filed | ||
| A85 | Still pending on 85-01-01 | ||
| BK | Erratum |
Free format text: CORRECTION TO PAMPHLET |
|
| V1 | Lapsed because of non-payment of the annual fee |
Effective date: 19991201 |