IL62948A - Process of selective solvolysis of 16-methyl corticosteroid esters - Google Patents

Process of selective solvolysis of 16-methyl corticosteroid esters

Info

Publication number
IL62948A
IL62948A IL62948A IL6294881A IL62948A IL 62948 A IL62948 A IL 62948A IL 62948 A IL62948 A IL 62948A IL 6294881 A IL6294881 A IL 6294881A IL 62948 A IL62948 A IL 62948A
Authority
IL
Israel
Prior art keywords
methyl
selective solvolysis
corticosteroid
esters
corticosteroid esters
Prior art date
Application number
IL62948A
Other languages
English (en)
Original Assignee
Pluriechemie Anstalt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pluriechemie Anstalt filed Critical Pluriechemie Anstalt
Publication of IL62948A publication Critical patent/IL62948A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16
    • C07J7/0055—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL62948A 1980-05-27 1981-05-25 Process of selective solvolysis of 16-methyl corticosteroid esters IL62948A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT71309A PT71309A (en) 1980-05-27 1980-05-27 Process of selective

Publications (1)

Publication Number Publication Date
IL62948A true IL62948A (en) 1984-08-31

Family

ID=20082722

Family Applications (1)

Application Number Title Priority Date Filing Date
IL62948A IL62948A (en) 1980-05-27 1981-05-25 Process of selective solvolysis of 16-methyl corticosteroid esters

Country Status (9)

Country Link
US (1) US4343739A (xx)
JP (1) JPS5767598A (xx)
KR (1) KR840001809B1 (xx)
CH (1) CH655320A5 (xx)
GB (1) GB2079754B (xx)
HK (1) HK52186A (xx)
IL (1) IL62948A (xx)
NL (1) NL182963C (xx)
PT (1) PT71309A (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2510582B1 (fr) 1981-07-30 1986-05-30 Sipsy Steroides esterifies en la position 17 et thio-esterifies en la position 21, leur procede de preparation et leur application comme medicament
IL66432A0 (en) * 1981-08-04 1982-12-31 Plurichemie Anstalt Process for the preparation of steroidal esters
KR890000664B1 (ko) * 1981-10-19 1989-03-22 바리 안소니 뉴우샘 미분된 베클로메타손 디프로피오네이트 일수화물의 제조방법
DE19741874A1 (de) 1997-09-23 1999-04-01 Henkel Ecolab Gmbh & Co Ohg Alkoholathaltiger Reiniger
FR2800635B1 (fr) * 1999-11-05 2002-07-26 Bio Merieux Nanospheres composites, conjugues derives, procede de preparation et leurs utilisations
CN105646630A (zh) * 2015-08-10 2016-06-08 山东泰华生物科技有限公司 一锅法制备丙酸氯倍他索中间体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418294B (sv) * 1974-03-27 1981-05-18 Plurichemie Anstalt Sett att framstella en 16alfa- eller 16beta-9alfa-klor eller -fluorsteroidester
JPS50157357A (xx) * 1974-06-10 1975-12-19

Also Published As

Publication number Publication date
CH655320A5 (de) 1986-04-15
JPS6411038B2 (xx) 1989-02-23
KR840001809B1 (ko) 1984-10-20
PT71309A (en) 1980-06-01
GB2079754B (en) 1984-11-07
GB2079754A (en) 1982-01-27
US4343739A (en) 1982-08-10
NL182963B (nl) 1988-01-18
JPS5767598A (en) 1982-04-24
HK52186A (en) 1986-07-18
NL182963C (nl) 1988-06-16
NL8102602A (nl) 1981-12-16
KR830006328A (ko) 1983-09-24

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