JPS5767598A - Novel solvent addition decomposition of 16-methylcorticosteroids - Google Patents

Novel solvent addition decomposition of 16-methylcorticosteroids

Info

Publication number
JPS5767598A
JPS5767598A JP56078794A JP7879481A JPS5767598A JP S5767598 A JPS5767598 A JP S5767598A JP 56078794 A JP56078794 A JP 56078794A JP 7879481 A JP7879481 A JP 7879481A JP S5767598 A JPS5767598 A JP S5767598A
Authority
JP
Japan
Prior art keywords
methylcorticosteroids
solvent addition
novel solvent
addition decomposition
decomposition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56078794A
Other languages
English (en)
Other versions
JPS6411038B2 (ja
Inventor
Biratsukusu Iwan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PURURIKEMII ANSUTARUTO
Plurichemie Anstalt
Original Assignee
PURURIKEMII ANSUTARUTO
Plurichemie Anstalt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PURURIKEMII ANSUTARUTO, Plurichemie Anstalt filed Critical PURURIKEMII ANSUTARUTO
Publication of JPS5767598A publication Critical patent/JPS5767598A/ja
Publication of JPS6411038B2 publication Critical patent/JPS6411038B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16
    • C07J7/0055—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP56078794A 1980-05-27 1981-05-26 Novel solvent addition decomposition of 16-methylcorticosteroids Granted JPS5767598A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT71309A PT71309A (en) 1980-05-27 1980-05-27 Process of selective

Publications (2)

Publication Number Publication Date
JPS5767598A true JPS5767598A (en) 1982-04-24
JPS6411038B2 JPS6411038B2 (ja) 1989-02-23

Family

ID=20082722

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56078794A Granted JPS5767598A (en) 1980-05-27 1981-05-26 Novel solvent addition decomposition of 16-methylcorticosteroids

Country Status (9)

Country Link
US (1) US4343739A (ja)
JP (1) JPS5767598A (ja)
KR (1) KR840001809B1 (ja)
CH (1) CH655320A5 (ja)
GB (1) GB2079754B (ja)
HK (1) HK52186A (ja)
IL (1) IL62948A (ja)
NL (1) NL182963C (ja)
PT (1) PT71309A (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2510582B1 (fr) 1981-07-30 1986-05-30 Sipsy Steroides esterifies en la position 17 et thio-esterifies en la position 21, leur procede de preparation et leur application comme medicament
IL66432A0 (en) * 1981-08-04 1982-12-31 Plurichemie Anstalt Process for the preparation of steroidal esters
KR890000664B1 (ko) * 1981-10-19 1989-03-22 바리 안소니 뉴우샘 미분된 베클로메타손 디프로피오네이트 일수화물의 제조방법
DE19741874A1 (de) 1997-09-23 1999-04-01 Henkel Ecolab Gmbh & Co Ohg Alkoholathaltiger Reiniger
FR2800635B1 (fr) * 1999-11-05 2002-07-26 Bio Merieux Nanospheres composites, conjugues derives, procede de preparation et leurs utilisations
CN105646630A (zh) * 2015-08-10 2016-06-08 山东泰华生物科技有限公司 一锅法制备丙酸氯倍他索中间体

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50157357A (ja) * 1974-06-10 1975-12-19

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2512915A1 (de) * 1974-03-27 1975-10-09 Plurichemie Anstalt 16-methyl-9 alpha-halogen-steroide ester, aether und verfahren zu ihrer herstellung

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50157357A (ja) * 1974-06-10 1975-12-19

Also Published As

Publication number Publication date
US4343739A (en) 1982-08-10
GB2079754A (en) 1982-01-27
HK52186A (en) 1986-07-18
NL182963B (nl) 1988-01-18
CH655320A5 (de) 1986-04-15
JPS6411038B2 (ja) 1989-02-23
NL182963C (nl) 1988-06-16
NL8102602A (nl) 1981-12-16
KR830006328A (ko) 1983-09-24
IL62948A (en) 1984-08-31
PT71309A (en) 1980-06-01
KR840001809B1 (ko) 1984-10-20
GB2079754B (en) 1984-11-07

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