NL178421B - AMINOTHIAZOLE DERIVATIVE WITH AN INFLAMMATORY AND IMMUNE SPONSULATING EFFECT AND A PHARMACEUTICAL PREPARATION CONTAINING SUCH AMINOTHIAZOLE DERIVATIVE. - Google Patents

AMINOTHIAZOLE DERIVATIVE WITH AN INFLAMMATORY AND IMMUNE SPONSULATING EFFECT AND A PHARMACEUTICAL PREPARATION CONTAINING SUCH AMINOTHIAZOLE DERIVATIVE.

Info

Publication number
NL178421B
NL178421B NLAANVRAGE7904337,A NL7904337A NL178421B NL 178421 B NL178421 B NL 178421B NL 7904337 A NL7904337 A NL 7904337A NL 178421 B NL178421 B NL 178421B
Authority
NL
Netherlands
Prior art keywords
aminothiazole derivative
sponsulating
immune
inflammatory
effect
Prior art date
Application number
NLAANVRAGE7904337,A
Other languages
Dutch (nl)
Other versions
NL178421C (en
NL7904337A (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NL7904337A publication Critical patent/NL7904337A/en
Publication of NL178421B publication Critical patent/NL178421B/en
Application granted granted Critical
Publication of NL178421C publication Critical patent/NL178421C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/42Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16BDEVICES FOR FASTENING OR SECURING CONSTRUCTIONAL ELEMENTS OR MACHINE PARTS TOGETHER, e.g. NAILS, BOLTS, CIRCLIPS, CLAMPS, CLIPS OR WEDGES; JOINTS OR JOINTING
    • F16B15/00Nails; Staples
    • F16B15/0023Nail plates
    • F16B2015/0076Nail plates with provisions for additional fastening means, e.g. hooks, holes for separate screws or nails, adhesive

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NLAANVRAGE7904337,A 1978-06-02 1979-06-01 AMINOTHIAZOLE DERIVATIVE WITH AN INFLAMMATORY AND IMMUNE SPONSULATING EFFECT AND A PHARMACEUTICAL PREPARATION CONTAINING SUCH AMINOTHIAZOLE DERIVATIVE. NL178421C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91183078A 1978-06-02 1978-06-02

Publications (3)

Publication Number Publication Date
NL7904337A NL7904337A (en) 1979-12-04
NL178421B true NL178421B (en) 1985-10-16
NL178421C NL178421C (en) 1986-03-17

Family

ID=25430923

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7904337,A NL178421C (en) 1978-06-02 1979-06-01 AMINOTHIAZOLE DERIVATIVE WITH AN INFLAMMATORY AND IMMUNE SPONSULATING EFFECT AND A PHARMACEUTICAL PREPARATION CONTAINING SUCH AMINOTHIAZOLE DERIVATIVE.

Country Status (36)

Country Link
JP (1) JPS5936988B2 (en)
AR (1) AR226285A1 (en)
AT (1) AT373248B (en)
AU (1) AU511242B2 (en)
BE (1) BE876732A (en)
CA (1) CA1117949A (en)
CH (1) CH639653A5 (en)
CS (1) CS216927B2 (en)
DD (1) DD144055A5 (en)
DE (1) DE2922523C2 (en)
DK (1) DK150068C (en)
EG (1) EG14354A (en)
ES (1) ES481220A1 (en)
FI (1) FI68820C (en)
FR (1) FR2427333A1 (en)
GB (1) GB2022085B (en)
GR (1) GR73142B (en)
HK (1) HK66487A (en)
HU (1) HU180045B (en)
IE (1) IE48426B1 (en)
IL (1) IL57450A (en)
IT (1) IT1121238B (en)
KE (1) KE3459A (en)
LU (1) LU81349A1 (en)
MY (1) MY8500318A (en)
NL (1) NL178421C (en)
NO (1) NO150760C (en)
NZ (1) NZ190623A (en)
PH (1) PH17020A (en)
PL (1) PL117515B1 (en)
PT (1) PT69718A (en)
SE (1) SE438333B (en)
SG (1) SG56184G (en)
SU (1) SU843746A3 (en)
YU (1) YU40997B (en)
ZA (1) ZA792729B (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57501565A (en) * 1980-10-24 1982-09-02
DE3264595D1 (en) * 1981-01-08 1985-08-14 Mitsui Toatsu Chemicals N-(4-phenyl-2-thiazolyl)carbamate derivatives, process for their preparation, and medicinal composition containing same
JPS57136579A (en) * 1981-01-21 1982-08-23 Mitsui Toatsu Chem Inc Thiazolylurea derivative, its preparation, and pharmaceutical composition containing the same
JPS57116067A (en) * 1981-01-12 1982-07-19 Sankyo Kagaku Kk Novel 8-quinolinesulfonyl derivative, its synthesis and use
WO1982002386A1 (en) * 1981-01-13 1982-07-22 Sakano Isao Aminothiazole derivatives,process for their preparation,and medicinal composition containing same
DE3273781D1 (en) * 1981-01-13 1986-11-20 Mitsui Toatsu Chemicals Novel thiazole compounds, process for their preparation, and medicinal composition containing same
JPS57154175A (en) * 1981-03-16 1982-09-22 Mitsui Toatsu Chem Inc 2-thiazoleamine derivative, its preparation, and drug composition comprising it
DE3227329A1 (en) * 1982-07-22 1984-01-26 Basf Ag, 6700 Ludwigshafen METHOD FOR PRODUCING 2-N, N-DISUBSTITUTED AMINOTHIAZOLES
WO1986003203A1 (en) * 1984-11-22 1986-06-05 Yoshitomi Pharmaceutical Industries, Ltd. Thienylthiazole derivatives
FR2581063B1 (en) * 1985-04-30 1987-07-17 Chauvin Blache Lab AMINO-2 THIAZOLES N-SUBSTITUTED, THEIR PREPARATION PROCESS AND THEIR APPLICATION IN THERAPEUTICS
JPS63152368A (en) * 1986-06-03 1988-06-24 Sumitomo Pharmaceut Co Ltd Novel aminoazole derivative and acid addition salt thereof
JPH075579B2 (en) * 1986-09-01 1995-01-25 吉富製薬株式会社 Aminothiazole compound
JPH0753666B2 (en) * 1987-09-14 1995-06-07 久光製薬株式会社 Anti-inflammatory agent consisting of substituted diphenylthiazole derivative
ES2111540T3 (en) * 1989-08-10 1998-03-16 Commw Scient Ind Res Org METHOD FOR THE PRODUCTION OF A MICROPARTICLE ELECTROSUSPENSION.
WO1992015570A1 (en) * 1991-03-07 1992-09-17 Hisamitsu Pharmaceutical Co., Inc. Novel diphenylthyazole derivative
FR2692893B1 (en) * 1992-06-24 1994-09-02 Sanofi Elf Branched alkylamino thiazole derivatives, processes for their preparation and pharmaceutical compositions containing them.
AU3201095A (en) * 1994-07-27 1996-02-22 G.D. Searle & Co. Substituted thiazoles for the treatment of inflammation
FR2754258B1 (en) 1996-10-08 1998-12-31 Sanofi Sa AMINOTHIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
DE60136530D1 (en) 2000-03-01 2008-12-24 Janssen Pharmaceutica Nv 2,4-DISUBSTITUTED THIAZOLYL DERIVATIVES
EP1423113A4 (en) * 2001-08-13 2007-04-18 Phenex Pharmaceuticals Ag Nr1h4 nuclear receptor binding compounds
WO2003027096A1 (en) * 2001-09-26 2003-04-03 Bayer Pharmaceuticals Corporation Substituted 3-pyridyl imidazoles as c17,20 lyase inhibitors
DE60328161D1 (en) 2002-01-11 2009-08-13 Daiichi Sankyo Co Ltd AMINO ALCOHOL DERIVATIVE OR PHOSPHONIC ACID DERIVATIVE AND MEDICAL COMPOSITION CONTAINING THEREOF
EP1555264A1 (en) * 2004-01-15 2005-07-20 Sireen AG Five-membered heterocyclic compounds as inhibitors of SRC family protein kinase.
CA2557536C (en) 2004-02-24 2010-07-13 Sankyo Company Limited Amino alcohol compound
CA2607617A1 (en) * 2005-05-09 2006-11-16 Achillion Pharmaceuticals, Inc. Thiazole compounds and methods of use
BRPI0706621A2 (en) 2006-01-18 2011-04-05 Amgen Inc compound, pharmaceutical composition, methods for treating a kinase-mediated disorder in a mammal and for treating a proliferation-related disorder in a mammal, and, use of the compound
WO2009011871A2 (en) 2007-07-17 2009-01-22 Amgen Inc. Thiadiazole modulators of pkb
JP2010533715A (en) 2007-07-17 2010-10-28 アムジエン・インコーポレーテツド Heterocyclic PKB regulator
WO2012170931A2 (en) 2011-06-10 2012-12-13 Calcimedica, Inc. Compounds that modulate intracellular calcium
US20130143927A1 (en) * 2011-06-10 2013-06-06 Calcimedica, Inc. Compounds that modulate intracellular calcium
WO2013059677A1 (en) 2011-10-19 2013-04-25 Calcimedica, Inc. Compounds that modulate intracellular calcium
CN110590785B (en) * 2019-09-23 2021-02-02 武汉大学 Aminothiazole compound, preparation method thereof and application of aminothiazole compound in resisting enterovirus 71

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3458526A (en) * 1966-09-26 1969-07-29 Upjohn Co Certain 2-amino-4,5-bis(p-methoxyphenyl)thiazoles

Also Published As

Publication number Publication date
JPS5936988B2 (en) 1984-09-06
JPS54160369A (en) 1979-12-19
ATA401679A (en) 1983-05-15
GB2022085A (en) 1979-12-12
CH639653A5 (en) 1983-11-30
CS216927B2 (en) 1982-12-31
DK150068B (en) 1986-12-01
HU180045B (en) 1983-01-28
NL178421C (en) 1986-03-17
NO150760B (en) 1984-09-03
IL57450A0 (en) 1979-09-30
FR2427333A1 (en) 1979-12-28
DK150068C (en) 1987-06-29
IE791069L (en) 1979-12-02
IT7923228A0 (en) 1979-06-01
GB2022085B (en) 1983-01-12
IE48426B1 (en) 1985-01-23
EG14354A (en) 1984-06-30
NZ190623A (en) 1984-07-06
FR2427333B1 (en) 1983-05-20
MY8500318A (en) 1985-12-31
DE2922523A1 (en) 1979-12-06
IL57450A (en) 1982-11-30
DE2922523C2 (en) 1982-10-21
AU4763479A (en) 1979-12-06
PH17020A (en) 1984-05-11
AR226285A1 (en) 1982-06-30
SE7904798L (en) 1979-12-03
FI68820C (en) 1985-11-11
IT1121238B (en) 1986-03-26
PL216030A1 (en) 1980-03-10
FI791754A (en) 1979-11-26
NO791831L (en) 1979-12-04
YU128879A (en) 1982-10-31
ES481220A1 (en) 1980-09-01
CA1117949A (en) 1982-02-09
DK177679A (en) 1979-12-03
BE876732A (en) 1979-12-03
GR73142B (en) 1984-02-09
SU843746A3 (en) 1981-06-30
ZA792729B (en) 1981-03-25
YU40997B (en) 1986-10-31
PL117515B1 (en) 1981-08-31
PT69718A (en) 1979-07-01
LU81349A1 (en) 1979-12-07
SE438333B (en) 1985-04-15
DD144055A5 (en) 1980-09-24
NL7904337A (en) 1979-12-04
KE3459A (en) 1984-10-12
NO150760C (en) 1984-12-12
AT373248B (en) 1983-12-27
SG56184G (en) 1985-03-08
AU511242B2 (en) 1980-08-07
FI68820B (en) 1985-07-31
HK66487A (en) 1987-09-25

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Legal Events

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A1A A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
V1 Lapsed because of non-payment of the annual fee