NL168515C - Werkwijze ter bereiding van derivaten van pyrimido-Ÿ4.5-bŸ-chinolin-4(3h)-on-2-carbonzuren en werkwijze ter bereiding van deze verbindingen bevattende preparaten met anti-ulcer-werking. - Google Patents

Werkwijze ter bereiding van derivaten van pyrimido-Ÿ4.5-bŸ-chinolin-4(3h)-on-2-carbonzuren en werkwijze ter bereiding van deze verbindingen bevattende preparaten met anti-ulcer-werking.

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Publication number
NL168515C
NL168515C NLAANVRAGE7614191,A NL7614191A NL168515C NL 168515 C NL168515 C NL 168515C NL 7614191 A NL7614191 A NL 7614191A NL 168515 C NL168515 C NL 168515C
Authority
NL
Netherlands
Prior art keywords
preparation
preparations
chinolin
pyrimido
derivatives
Prior art date
Application number
NLAANVRAGE7614191,A
Other languages
English (en)
Dutch (nl)
Other versions
NL7614191A (nl
NL168515B (nl
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NL7614191A publication Critical patent/NL7614191A/xx
Publication of NL168515B publication Critical patent/NL168515B/xx
Application granted granted Critical
Publication of NL168515C publication Critical patent/NL168515C/xx

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NLAANVRAGE7614191,A 1976-01-20 1976-12-21 Werkwijze ter bereiding van derivaten van pyrimido-Ÿ4.5-bŸ-chinolin-4(3h)-on-2-carbonzuren en werkwijze ter bereiding van deze verbindingen bevattende preparaten met anti-ulcer-werking. NL168515C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/650,714 US4011324A (en) 1976-01-20 1976-01-20 Esters and amides of pyrimido[4,5-b]quinolin-4(3H)-one-2-carboxylic acids as antiulcer agents

Publications (3)

Publication Number Publication Date
NL7614191A NL7614191A (nl) 1977-07-22
NL168515B NL168515B (nl) 1981-11-16
NL168515C true NL168515C (nl) 1982-04-16

Family

ID=24609991

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7614191,A NL168515C (nl) 1976-01-20 1976-12-21 Werkwijze ter bereiding van derivaten van pyrimido-Ÿ4.5-bŸ-chinolin-4(3h)-on-2-carbonzuren en werkwijze ter bereiding van deze verbindingen bevattende preparaten met anti-ulcer-werking.

Country Status (10)

Country Link
US (1) US4011324A (da)
JP (2) JPS5289700A (da)
BE (1) BE849647A (da)
DE (1) DE2700216A1 (da)
DK (1) DK575776A (da)
FR (1) FR2361892A1 (da)
GB (1) GB1531681A (da)
IE (1) IE43964B1 (da)
LU (1) LU76457A1 (da)
NL (1) NL168515C (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2757915A1 (de) * 1976-12-28 1978-07-06 Mitsubishi Yuka Pharma Pyrimidochinoxalinderivate, verfahren zur herstellung derselben und arzneimittel zur behandlung von allergischem asthma
DE3138550A1 (de) * 1981-09-28 1983-04-07 Boehringer Ingelheim KG, 6507 Ingelheim Substituierte 2-phenyl-2-(pyridyloxy)-ethylamine und isostere verbindungen, verfahren zu ihrer herstellung und verwendung
US4551460A (en) * 1982-05-10 1985-11-05 Hoffmann-La Roche Inc. Pyrido[2,1-b]quinazoline derivatives useful as agents for treatment of allergic conditions and vascular disorders involving thrombosis
DE3232620A1 (de) * 1982-09-02 1984-03-08 Hoechst Ag, 6230 Frankfurt 10-phenyl1-1,3,9-triazaanthracene und diese enthaltendes photopolymerisierbares gemisch
US6545004B1 (en) 1999-10-27 2003-04-08 Cytokinetics, Inc. Methods and compositions utilizing quinazolinones
US7230000B1 (en) 1999-10-27 2007-06-12 Cytokinetics, Incorporated Methods and compositions utilizing quinazolinones
WO2002094790A1 (fr) * 2001-05-23 2002-11-28 Mitsubishi Pharma Corporation Compose heterocyclique condense et son utilisation medicale
ITMI20012060A1 (it) * 2001-10-05 2003-04-05 Recordati Chem Pharm Nuovi eterocilcli n-acilati
US7009049B2 (en) * 2002-02-15 2006-03-07 Cytokinetics, Inc. Syntheses of quinazolinones
JP2006508030A (ja) * 2002-05-09 2006-03-09 サイトキネティクス・インコーポレーテッド ピリミジノン化合物、組成物および方法
WO2003097053A1 (en) 2002-05-09 2003-11-27 Cytokinetics, Inc. Compounds, compositions, and methods
WO2003103575A2 (en) * 2002-05-23 2003-12-18 Cytokinetics, Inc. Compounds, compositions, and methods
US7041676B2 (en) * 2002-06-14 2006-05-09 Cytokinetics, Inc. Compounds, compositions, and methods
EP1537089A4 (en) * 2002-07-23 2008-04-16 Cytokinetics Inc CONNECTIONS, COMPOSITIONS AND PROCEDURES
JP2005536553A (ja) * 2002-08-21 2005-12-02 サイトキネティクス・インコーポレーテッド 化合物、組成物および方法
US7557115B2 (en) * 2002-09-30 2009-07-07 Cytokinetics, Inc. Compounds, compositions, and methods
EP1682534A2 (en) * 2003-11-03 2006-07-26 Cytokinetics, Inc. Pyrimidin-4-one compounds, compositions, and methods
US20050148593A1 (en) * 2003-11-07 2005-07-07 Gustave Bergnes Compounds, compositions, and methods
EP1692112A4 (en) * 2003-12-08 2008-09-24 Cytokinetics Inc COMPOUNDS, COMPOSITIONS, AND METHODS
EP1740551B9 (en) * 2004-04-30 2013-01-16 Takeda Pharmaceutical Company Limited Heterocyclic amide compound and use thereof as an mmp-13 inhibitor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3414574A (en) * 1967-04-21 1968-12-03 Sandoz Ag Certain pyrimido (4, 5-b) indoles and intermediates employed in their preparation
US3974161A (en) * 1974-02-20 1976-08-10 Pfizer Inc. Fused pyrimidin-4(3H)-ones as antiallergy agents
GB1458205A (en) * 1973-04-13 1976-12-08 Pfizer Fused pyrimidin-4- 3h-ones as antiallergy agents

Also Published As

Publication number Publication date
FR2361892A1 (fr) 1978-03-17
DK575776A (da) 1977-07-21
IE43964B1 (en) 1981-07-15
NL7614191A (nl) 1977-07-22
BE849647A (fr) 1977-06-20
JPS5470433A (en) 1979-06-06
US4011324A (en) 1977-03-08
FR2361892B1 (da) 1980-09-19
IE43964L (en) 1977-07-20
JPS5289700A (en) 1977-07-27
GB1531681A (en) 1978-11-08
LU76457A1 (da) 1977-07-05
NL168515B (nl) 1981-11-16
DE2700216A1 (de) 1977-07-28

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Legal Events

Date Code Title Description
V2 Lapsed due to non-payment of the last due maintenance fee for the patent application