BE849647A - Esters et amides des acides pyrimido (4,5-b) quinolein-4(3h)-one-2-carboxyliques, en tant qu'agents antiulceres - Google Patents

Esters et amides des acides pyrimido (4,5-b) quinolein-4(3h)-one-2-carboxyliques, en tant qu'agents antiulceres

Info

Publication number
BE849647A
BE849647A BE1007837A BE1007837A BE849647A BE 849647 A BE849647 A BE 849647A BE 1007837 A BE1007837 A BE 1007837A BE 1007837 A BE1007837 A BE 1007837A BE 849647 A BE849647 A BE 849647A
Authority
BE
Belgium
Prior art keywords
quinolein
amids
pyrimido
esters
carboxylic acids
Prior art date
Application number
BE1007837A
Other languages
English (en)
French (fr)
Inventor
Th H Althuis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE849647A publication Critical patent/BE849647A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BE1007837A 1976-01-20 1976-12-20 Esters et amides des acides pyrimido (4,5-b) quinolein-4(3h)-one-2-carboxyliques, en tant qu'agents antiulceres BE849647A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/650,714 US4011324A (en) 1976-01-20 1976-01-20 Esters and amides of pyrimido[4,5-b]quinolin-4(3H)-one-2-carboxylic acids as antiulcer agents

Publications (1)

Publication Number Publication Date
BE849647A true BE849647A (fr) 1977-06-20

Family

ID=24609991

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1007837A BE849647A (fr) 1976-01-20 1976-12-20 Esters et amides des acides pyrimido (4,5-b) quinolein-4(3h)-one-2-carboxyliques, en tant qu'agents antiulceres

Country Status (10)

Country Link
US (1) US4011324A (xx)
JP (2) JPS5289700A (xx)
BE (1) BE849647A (xx)
DE (1) DE2700216A1 (xx)
DK (1) DK575776A (xx)
FR (1) FR2361892A1 (xx)
GB (1) GB1531681A (xx)
IE (1) IE43964B1 (xx)
LU (1) LU76457A1 (xx)
NL (1) NL168515C (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2757915A1 (de) * 1976-12-28 1978-07-06 Mitsubishi Yuka Pharma Pyrimidochinoxalinderivate, verfahren zur herstellung derselben und arzneimittel zur behandlung von allergischem asthma
DE3138550A1 (de) * 1981-09-28 1983-04-07 Boehringer Ingelheim KG, 6507 Ingelheim Substituierte 2-phenyl-2-(pyridyloxy)-ethylamine und isostere verbindungen, verfahren zu ihrer herstellung und verwendung
US4551460A (en) * 1982-05-10 1985-11-05 Hoffmann-La Roche Inc. Pyrido[2,1-b]quinazoline derivatives useful as agents for treatment of allergic conditions and vascular disorders involving thrombosis
DE3232620A1 (de) * 1982-09-02 1984-03-08 Hoechst Ag, 6230 Frankfurt 10-phenyl1-1,3,9-triazaanthracene und diese enthaltendes photopolymerisierbares gemisch
US7230000B1 (en) 1999-10-27 2007-06-12 Cytokinetics, Incorporated Methods and compositions utilizing quinazolinones
US6545004B1 (en) * 1999-10-27 2003-04-08 Cytokinetics, Inc. Methods and compositions utilizing quinazolinones
JPWO2002094790A1 (ja) * 2001-05-23 2004-09-09 三菱ウェルファーマ株式会社 縮合ヘテロ環化合物およびその医薬用途
ITMI20012060A1 (it) * 2001-10-05 2003-04-05 Recordati Chem Pharm Nuovi eterocilcli n-acilati
CA2475879A1 (en) * 2002-02-15 2003-08-28 Cytokinetics, Inc. Synthesis of quinazolinones
EP1553931A4 (en) * 2002-05-09 2006-08-30 Cytokinetics Inc COMPOUNDS, COMPOSITIONS AND METHODS
WO2003094839A2 (en) * 2002-05-09 2003-11-20 Cytokinetics, Inc. Pyrimidinone compounds, compositions and methods
EP1513820A4 (en) * 2002-05-23 2006-09-13 Cytokinetics Inc COMPOUNDS, COMPOSITIONS AND METHODS
US7041676B2 (en) * 2002-06-14 2006-05-09 Cytokinetics, Inc. Compounds, compositions, and methods
US7211580B2 (en) * 2002-07-23 2007-05-01 Cytokinetics, Incorporated Compounds, compositions, and methods
JP2005536553A (ja) * 2002-08-21 2005-12-02 サイトキネティクス・インコーポレーテッド 化合物、組成物および方法
US7557115B2 (en) * 2002-09-30 2009-07-07 Cytokinetics, Inc. Compounds, compositions, and methods
EP1682534A2 (en) * 2003-11-03 2006-07-26 Cytokinetics, Inc. Pyrimidin-4-one compounds, compositions, and methods
US20050148593A1 (en) * 2003-11-07 2005-07-07 Gustave Bergnes Compounds, compositions, and methods
WO2005061460A1 (en) * 2003-12-08 2005-07-07 Cytokinetics, Inc. Compounds, compositions, and methods
RU2006142305A (ru) 2004-04-30 2008-06-10 Такеда Фармасьютикал Компани Лимитед (Jp) Гетероциклическое амидное соединение и его применение в качестве ингибитора ммр-3

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3414574A (en) * 1967-04-21 1968-12-03 Sandoz Ag Certain pyrimido (4, 5-b) indoles and intermediates employed in their preparation
US3974161A (en) * 1974-02-20 1976-08-10 Pfizer Inc. Fused pyrimidin-4(3H)-ones as antiallergy agents
GB1458205A (en) * 1973-04-13 1976-12-08 Pfizer Fused pyrimidin-4- 3h-ones as antiallergy agents

Also Published As

Publication number Publication date
US4011324A (en) 1977-03-08
IE43964L (en) 1977-07-20
DE2700216A1 (de) 1977-07-28
NL7614191A (nl) 1977-07-22
NL168515C (nl) 1982-04-16
NL168515B (nl) 1981-11-16
LU76457A1 (xx) 1977-07-05
IE43964B1 (en) 1981-07-15
FR2361892A1 (fr) 1978-03-17
DK575776A (da) 1977-07-21
GB1531681A (en) 1978-11-08
FR2361892B1 (xx) 1980-09-19
JPS5470433A (en) 1979-06-06
JPS5289700A (en) 1977-07-27

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