NL127065C - - Google Patents

Info

Publication number
NL127065C
NL127065C NL127065DA NL127065C NL 127065 C NL127065 C NL 127065C NL 127065D A NL127065D A NL 127065DA NL 127065 C NL127065 C NL 127065C
Authority
NL
Netherlands
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication of NL127065C publication Critical patent/NL127065C/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
NL127065D 1964-04-22 NL127065C (US07368563-20080506-C00074.png)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB16696/64A GB1100281A (en) 1964-04-22 1964-04-22 New spiro-decane derivatives and process for the preparation thereof

Publications (1)

Publication Number Publication Date
NL127065C true NL127065C (US07368563-20080506-C00074.png)

Family

ID=10081982

Family Applications (2)

Application Number Title Priority Date Filing Date
NL127065D NL127065C (US07368563-20080506-C00074.png) 1964-04-22
NL6504602A NL6504602A (US07368563-20080506-C00074.png) 1964-04-22 1965-04-12

Family Applications After (1)

Application Number Title Priority Date Filing Date
NL6504602A NL6504602A (US07368563-20080506-C00074.png) 1964-04-22 1965-04-12

Country Status (9)

Country Link
US (1) US3399192A (US07368563-20080506-C00074.png)
BE (1) BE662817A (US07368563-20080506-C00074.png)
CH (1) CH454160A (US07368563-20080506-C00074.png)
DE (1) DE1620262C3 (US07368563-20080506-C00074.png)
ES (2) ES312091A1 (US07368563-20080506-C00074.png)
FR (2) FR1441575A (US07368563-20080506-C00074.png)
GB (1) GB1100281A (US07368563-20080506-C00074.png)
NL (2) NL6504602A (US07368563-20080506-C00074.png)
SE (1) SE307793B (US07368563-20080506-C00074.png)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL129025C (US07368563-20080506-C00074.png) * 1965-04-29
US3542729A (en) * 1968-03-19 1970-11-24 Sankyo Co Stabilization of synthetic polymers
BE790675A (fr) * 1971-10-29 1973-04-27 Science Union & Cie Nouveaux derives de l'oxa-1 diaza-3,8 spiro (4,5) decane
US4244961A (en) * 1978-10-26 1981-01-13 Syntex (U.S.A.) Inc. 1-Oxa-3,8-diazaspiro[4.5]decan-2-ones antihypertensive agents
US4255432A (en) * 1979-09-06 1981-03-10 Syntex (U.S.A.) Inc. 8-[2-3-Indolyl)ethyl]-1-oxa-3-,8-diazaspiro[4.5]decan-2-ones, pharmaceutical compositions thereof and methods of use thereof
ES517622A0 (es) * 1982-11-23 1983-12-16 Faes Procedimiento de preparacion de un nuevo espirodecano.
HU204054B (en) * 1989-08-10 1991-11-28 Richter Gedeon Vegyeszet Process for producing new 1-oxa-2-oxo-8-azaspiro(4,5)decane derivatives and pharmaceutical compositions comprising same
YU150489A (sh) * 1989-08-10 1992-12-21 W.L. Gore & Co. Gmbh. Uređaj za ispitivanje odevnih predmeta na nepromočivost
FR2666583B1 (fr) * 1990-09-06 1994-09-09 Adir Nouveaux derives du spiro [4.5] decane, leur procede de preparation et leurs compositions pharmaceutiques les renfermant.
FR2734265B1 (fr) * 1995-05-17 1997-06-13 Adir Nouveaux composes spiro heterocycliques, leur procede de preparation et les compositions pharmaceutiques les contenant
US6982251B2 (en) * 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
EP1671650A1 (en) * 2001-01-26 2006-06-21 Schering Corporation Combinations of nicotinic acid and derivatives thereof and sterol absorption inhibitor(s) and treatments for vascular indications
PT1413331E (pt) * 2001-01-26 2007-12-18 Schering Corp Combinações do activador do receptor activado por proliferador do peroxisoma (ppar) fenofibrato e inibidor da absorção de esterol para indicações vasculares.
US7071181B2 (en) * 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
DE60220269T2 (de) * 2001-01-26 2008-01-17 Schering Corp. Kombinationen eines hemmers der sterolabsorption und eines kardiovaskulären wirkstoffes zur behandlung von kardiovaskulären indikationen
CN1658903A (zh) * 2001-01-26 2005-08-24 先灵公司 用于治疗血管性疾病的固醇吸收抑制剂与血液调节剂的组合
ME00145B (me) * 2001-01-26 2010-10-10 Merck Sharp & Dohme Upotreba supstituisanih jedinjenja azetidinona za lečenje sitosterolemije
JP2004521894A (ja) * 2001-01-26 2004-07-22 シェーリング コーポレイション 胆汁酸金属イオン封鎖剤およびステロール吸収阻害剤の併用および血管適応症の治療
PT1392287E (pt) * 2001-05-25 2007-02-28 Schering Corp Métodos para tratamento de doença de alzheimer e/ou regulação dos níveis de peptídeos β amilóide num sujeito
DE10130020A1 (de) * 2001-06-25 2003-12-04 Gruenenthal Gmbh Substituierte 1-Oxa-2,8-diaza-spiro[4.5]dec-2-en-derivate
DE10146275A1 (de) 2001-09-18 2003-04-24 Gruenenthal Gmbh Kombination ausgewählter Opioide mit Muscarin-Antagonisten zur Therapie der Harninkontinenz
US7056906B2 (en) * 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
CN1556700A (zh) * 2001-09-21 2004-12-22 ���鹫˾ 使用甾醇吸收抑制剂治疗或预防脉管炎的方法
US20030119808A1 (en) * 2001-09-21 2003-06-26 Schering Corporation Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects
US7053080B2 (en) * 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
ATE345793T1 (de) * 2001-09-21 2006-12-15 Schering Corp Behandlung von xanthom mittels azetidinon- derivate als hemmer der sterol absorption
CA2495962A1 (en) 2002-08-19 2004-03-04 Pfizer Products Inc. Combination therapy for hyperproliferative diseases
MXPA05004810A (es) * 2002-11-06 2005-07-22 Schering Corp Inhibidores de la absorcion del colesterol para el tratamiento de la desmielinizacion.
US7208486B2 (en) 2003-03-07 2007-04-24 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
WO2004081002A1 (en) 2003-03-07 2004-09-23 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
CN1756755A (zh) * 2003-03-07 2006-04-05 先灵公司 取代的2-吖丁啶酮化合物、其制剂及其治疗高胆甾醇血症的用途
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
WO2005046797A2 (en) * 2003-11-05 2005-05-26 Schering Corporation Combinations of lipid modulating agents and substituted azetidinones and treatments for vascular conditions
KR100863854B1 (ko) * 2004-02-10 2008-10-15 에프. 호프만-라 로슈 아게 케모카인 ccr5 수용체 조절제
US20060063803A1 (en) * 2004-09-23 2006-03-23 Pfizer Inc 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US8383660B2 (en) 2006-03-10 2013-02-26 Pfizer Inc. Dibenzyl amine compounds and derivatives
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
EP2094643B1 (en) 2006-12-01 2012-02-29 Bristol-Myers Squibb Company N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases
EP2142555A1 (en) * 2007-03-29 2010-01-13 F. Hoffmann-Roche AG Heterocyclic antiviral compounds
MX354786B (es) 2007-06-04 2018-03-21 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
ES2627848T3 (es) 2008-06-04 2017-07-31 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
ES2624828T3 (es) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CN102766147B (zh) * 2012-08-03 2015-07-15 无锡药兴医药科技有限公司 一种芬司匹利及其氢卤酸盐的制备方法
US9486494B2 (en) 2013-03-15 2016-11-08 Synergy Pharmaceuticals, Inc. Compositions useful for the treatment of gastrointestinal disorders
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
WO2014170786A1 (en) 2013-04-17 2014-10-23 Pfizer Inc. N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
KR102272746B1 (ko) 2013-06-05 2021-07-08 보슈 헬스 아일랜드 리미티드 구아닐레이트 사이클라제 c의 초순수 작용제, 및 이의 제조 및 사용 방법
GB201416346D0 (en) * 2014-09-16 2014-10-29 Shire Internat Gmbh Spirocyclic derivatives
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
WO2020150473A2 (en) 2019-01-18 2020-07-23 Dogma Therapeutics, Inc. Pcsk9 inhibitors and methods of use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3193559A (en) * 1965-07-06 New derivatives of z-oxazolidinones
US2437388A (en) * 1948-03-09 Z-oxazolidone compounds and proc
US2500714A (en) * 1944-10-30 1950-03-14 Abbott Lab 4-phenyl-1-alkyl isonipecotic acid lactones
US3054794A (en) * 1958-01-17 1962-09-18 Us Vitamin Pharm Corp Process for preparing 3-(aminoalkyl)-oxazolidine-2, 4-diones
GB974134A (en) * 1963-03-28 1964-11-04 Science Union Et Compagnie Soc Oxazolidinone derivatives

Also Published As

Publication number Publication date
NL6504602A (US07368563-20080506-C00074.png) 1965-10-25
FR4463M (US07368563-20080506-C00074.png) 1966-09-26
FR1441575A (fr) 1966-06-10
BE662817A (US07368563-20080506-C00074.png) 1965-10-21
DE1620262C3 (de) 1980-07-03
SE307793B (US07368563-20080506-C00074.png) 1969-01-20
DE1620262B2 (de) 1979-10-11
GB1100281A (en) 1968-01-24
DE1620262A1 (de) 1972-03-23
US3399192A (en) 1968-08-27
ES312091A1 (es) 1965-10-01
CH454160A (fr) 1968-04-15
ES361975A2 (es) 1971-01-16

Similar Documents

Publication Publication Date Title
FR4463M (US07368563-20080506-C00074.png)
BE642508A (US07368563-20080506-C00074.png)
BE637777A (US07368563-20080506-C00074.png)
BE642243A (US07368563-20080506-C00074.png)
BE661153A (US07368563-20080506-C00074.png)
BE660838A (US07368563-20080506-C00074.png)
BE660568A (US07368563-20080506-C00074.png)
BE660327A (US07368563-20080506-C00074.png)
BE642212A (US07368563-20080506-C00074.png)
BE642114A (US07368563-20080506-C00074.png)
BE660306A (US07368563-20080506-C00074.png)
BE660042A (US07368563-20080506-C00074.png)
BE642104A (US07368563-20080506-C00074.png)
BE659894A (US07368563-20080506-C00074.png)
BE659677A (US07368563-20080506-C00074.png)
BE659196A (US07368563-20080506-C00074.png)
BE659140A (US07368563-20080506-C00074.png)
BE637950A (US07368563-20080506-C00074.png)
BE658381A (US07368563-20080506-C00074.png)
BE658230A (US07368563-20080506-C00074.png)
BE657981A (US07368563-20080506-C00074.png)
BE656471A (US07368563-20080506-C00074.png)
BE654314A (US07368563-20080506-C00074.png)
BE652455A (US07368563-20080506-C00074.png)
BE642973A (US07368563-20080506-C00074.png)