NI201000214A - Moduladores de diamino-piridina, pirimidina, y piridazina del receptor de la histamina h4. - Google Patents

Moduladores de diamino-piridina, pirimidina, y piridazina del receptor de la histamina h4.

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Publication number
NI201000214A
NI201000214A NI201000214A NI201000214A NI201000214A NI 201000214 A NI201000214 A NI 201000214A NI 201000214 A NI201000214 A NI 201000214A NI 201000214 A NI201000214 A NI 201000214A NI 201000214 A NI201000214 A NI 201000214A
Authority
NI
Nicaragua
Prior art keywords
pyrimidine
pyridine
receptor
modulators
pyridazine
Prior art date
Application number
NI201000214A
Other languages
English (en)
Inventor
Cai Hui
Chavez Frank
M Savall Brad
J Dunford Paul
J Greenspan Andrew
P Meduna Steven
A Quiroz Jorge
L Tays Kevin
L Thurmond Robin
Wei Jianmei
L Wolin Ronald
Zhang Xiaohu
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41417123&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NI201000214(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NI201000214A publication Critical patent/NI201000214A/es

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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Abstract

Compuestos de diamino-piridina, pirimidina y piridazina que pueden ser utilizados como moduladores del receptor H4, y en composiciones farmacéuticas y métodos para el tratamiento de estados de enfermedad, trastornos, y condiciones mediadas por la actividad del receptor H4, tales como alergias, asma, enfermedades autoinmunes, y prurito.
NI201000214A 2008-06-12 2010-12-10 Moduladores de diamino-piridina, pirimidina, y piridazina del receptor de la histamina h4. NI201000214A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6103908P 2008-06-12 2008-06-12
US11442508P 2008-11-13 2008-11-13
US11441608P 2008-11-13 2008-11-13

Publications (1)

Publication Number Publication Date
NI201000214A true NI201000214A (es) 2011-08-01

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NI201000214A NI201000214A (es) 2008-06-12 2010-12-10 Moduladores de diamino-piridina, pirimidina, y piridazina del receptor de la histamina h4.

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US (3) US8841287B2 (es)
EP (1) EP2315521B1 (es)
JP (1) JP5658662B2 (es)
KR (1) KR101600278B1 (es)
CN (1) CN102118969B (es)
AU (1) AU2009257434B2 (es)
BR (1) BRPI0915720A2 (es)
CA (1) CA2727684C (es)
CO (1) CO6321192A2 (es)
CR (1) CR20110029A (es)
EA (1) EA018198B1 (es)
EC (1) ECSP10010675A (es)
HK (1) HK1157569A1 (es)
IL (1) IL209593A (es)
MX (1) MX2010013726A (es)
MY (1) MY158927A (es)
NI (1) NI201000214A (es)
NZ (1) NZ589532A (es)
PE (1) PE20110061A1 (es)
WO (1) WO2009152325A1 (es)
ZA (1) ZA201100298B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ571691A (en) 2006-03-31 2011-07-29 Janssen Pharmaceutica Nv Benzoimidazol-2-yl pyrimidines and pyrazines as modulators of the histamine H4 receptor
BRPI0915720A2 (pt) 2008-06-12 2015-08-04 Janssen Pharmaceutica Nv Moduladores de diaminopiridina, pirimidina, e piridazina do receptor de histamina h4
BRPI0915526A2 (pt) * 2008-06-12 2016-01-26 Janssen Pharmaceutica Nv uso de um antagonista da histamina h4 para o tratamento de aderências pós-operatórias
US9371311B2 (en) 2008-06-30 2016-06-21 Janssen Pharmaceutica Nv Benzoimidazol-2-yl pyrimidine derivatives
MX2011012343A (es) * 2009-05-19 2011-12-14 Dow Agrosciences Llc Compuestos y metodos para controlar hongos.
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