MX2010013726A - Moduladores de diamino-piridina, pirimidina, y piridazina del receptor h4 de histamina. - Google Patents

Moduladores de diamino-piridina, pirimidina, y piridazina del receptor h4 de histamina.

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Publication number
MX2010013726A
MX2010013726A MX2010013726A MX2010013726A MX2010013726A MX 2010013726 A MX2010013726 A MX 2010013726A MX 2010013726 A MX2010013726 A MX 2010013726A MX 2010013726 A MX2010013726 A MX 2010013726A MX 2010013726 A MX2010013726 A MX 2010013726A
Authority
MX
Mexico
Prior art keywords
diamino
pyrimidine
pyridine
receptor
modulators
Prior art date
Application number
MX2010013726A
Other languages
English (en)
Inventor
Hui Cai
Jianmei Wei
Brad M Savall
Xiaohu Zhang
Frank Chavez
Ronald L Wolin
Paul J Dunford
Andrew J Greenspan
Steven P Meduna
Jorge A Quiroz
Kevin L Tays
Robin L Thurmond
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41417123&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2010013726(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of MX2010013726A publication Critical patent/MX2010013726A/es

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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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Abstract

Compuestos de diamino-piridina, pirimidina y piridazina que se pueden usar como moduladores del receptor H4, y en composiciones farmacéuticas y métodos para el tratamiento de estados de enfermedad, trastornos, y afecciones mediadas por la actividad del receptor H4, tales como alergia, asma, enfermedades autoinmunes, y prurito.
MX2010013726A 2008-06-12 2009-06-11 Moduladores de diamino-piridina, pirimidina, y piridazina del receptor h4 de histamina. MX2010013726A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US6103908P 2008-06-12 2008-06-12
US11441608P 2008-11-13 2008-11-13
US11442508P 2008-11-13 2008-11-13
PCT/US2009/047033 WO2009152325A1 (en) 2008-06-12 2009-06-11 Diamino-pyridine, pyrimidine, and pyridazine modulators of the histamine h4 receptor

Publications (1)

Publication Number Publication Date
MX2010013726A true MX2010013726A (es) 2011-01-14

Family

ID=41417123

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010013726A MX2010013726A (es) 2008-06-12 2009-06-11 Moduladores de diamino-piridina, pirimidina, y piridazina del receptor h4 de histamina.

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Country Link
US (3) US8841287B2 (es)
EP (1) EP2315521B1 (es)
JP (1) JP5658662B2 (es)
KR (1) KR101600278B1 (es)
CN (1) CN102118969B (es)
AU (1) AU2009257434B2 (es)
BR (1) BRPI0915720A2 (es)
CA (1) CA2727684C (es)
CO (1) CO6321192A2 (es)
CR (1) CR20110029A (es)
EA (1) EA018198B1 (es)
EC (1) ECSP10010675A (es)
HK (1) HK1157569A1 (es)
IL (1) IL209593A (es)
MX (1) MX2010013726A (es)
MY (1) MY158927A (es)
NI (1) NI201000214A (es)
NZ (1) NZ589532A (es)
PE (1) PE20110061A1 (es)
WO (1) WO2009152325A1 (es)
ZA (1) ZA201100298B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2007752E (pt) 2006-03-31 2010-10-18 Janssen Pharmaceutica Nv Benzoimidazol-2-il pirimidinas e pirazinas como moduladores do receptor de histamina h4
MY158927A (en) 2008-06-12 2016-11-30 Janssen Pharmaceutica Nv Diamino-pyridine, pyrimidine, and pyridazine modulators of the histamine h4 receptor
CA2727627C (en) * 2008-06-12 2018-02-13 Janssen Pharmaceutica Nv Use of histamine h4 antagonist for the treatment of post-operative adhesions
US9371311B2 (en) 2008-06-30 2016-06-21 Janssen Pharmaceutica Nv Benzoimidazol-2-yl pyrimidine derivatives
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