MY8700184A - 6 7-benzomorphan derivatives processes for their production pharmaceutical compositions containing said derivatives and their use as pharmaceuticals - Google Patents

6 7-benzomorphan derivatives processes for their production pharmaceutical compositions containing said derivatives and their use as pharmaceuticals

Info

Publication number
MY8700184A
MY8700184A MY184/87A MY8700184A MY8700184A MY 8700184 A MY8700184 A MY 8700184A MY 184/87 A MY184/87 A MY 184/87A MY 8700184 A MY8700184 A MY 8700184A MY 8700184 A MY8700184 A MY 8700184A
Authority
MY
Malaysia
Prior art keywords
derivatives
hydrogen
pharmaceuticals
pharmaceutical compositions
compositions containing
Prior art date
Application number
MY184/87A
Other languages
English (en)
Inventor
Anthony Marie Dr Akkerman
Hermanus C C K Van Dr Bakel
Roelof Christian Klaas Smit
Hendricus Bernardus Anto Welle
Magda Dr Marko
Original Assignee
Acf Chemiefarma Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acf Chemiefarma Nv filed Critical Acf Chemiefarma Nv
Publication of MY8700184A publication Critical patent/MY8700184A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MY184/87A 1979-10-23 1987-12-30 6 7-benzomorphan derivatives processes for their production pharmaceutical compositions containing said derivatives and their use as pharmaceuticals MY8700184A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7907800A NL7907800A (nl) 1979-10-23 1979-10-23 Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan, farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werkwijze voor het bereiden van deze verbindingen en de farmaceutische preparaten.

Publications (1)

Publication Number Publication Date
MY8700184A true MY8700184A (en) 1987-12-31

Family

ID=19834064

Family Applications (1)

Application Number Title Priority Date Filing Date
MY184/87A MY8700184A (en) 1979-10-23 1987-12-30 6 7-benzomorphan derivatives processes for their production pharmaceutical compositions containing said derivatives and their use as pharmaceuticals

Country Status (17)

Country Link
US (2) US4425353A (fi)
EP (1) EP0028717B1 (fi)
JP (1) JPS5686164A (fi)
AT (1) ATE8990T1 (fi)
AU (1) AU539310B2 (fi)
CA (1) CA1155840A (fi)
DE (1) DE3068961D1 (fi)
DK (1) DK435380A (fi)
ES (1) ES496167A0 (fi)
FI (1) FI67373C (fi)
IE (1) IE50667B1 (fi)
IL (1) IL61324A (fi)
MY (1) MY8700184A (fi)
NL (1) NL7907800A (fi)
NZ (1) NZ195329A (fi)
PT (1) PT71949B (fi)
ZA (1) ZA806528B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4579950A (en) * 1982-08-20 1986-04-01 Hoechst-Roussel Pharmaceuticals Inc. Intermediates for spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine] compounds
ZA887087B (en) * 1987-09-24 1989-06-28 Hoechst Roussel Pharma 2,6-methanopyrrolo-3-benzazocines,a process and intermediates for their preparation and their use as medicaments
DE4121821A1 (de) * 1991-07-02 1993-01-14 Boehringer Ingelheim Kg Neue benzomorphane und ihre verwendung als arzneimittel
DE19528472A1 (de) * 1995-08-03 1997-02-06 Boehringer Ingelheim Kg Neues Verfahren zur Herstellung von Norbenzomorphan einer Zwischenstufe bei Herstellung von pharmazeutisch wertvollen Benzomorphanderivaten, insbesondere von (-)-(1R,5S,S"R)-3'-Hydroxy-2-(2-methoxypropyl-)-5,9,9-trimethyl-6,7 benzomorphan
WO1999020223A2 (en) 1997-10-20 1999-04-29 Novo Nordisk A/S Luteinising hormone antagonists useful for treatment of estrogen deficiencies, or as a contraceptive
US6136980A (en) * 1998-05-01 2000-10-24 Boehringer Ingelheim Kg Method of preparing norbenzomorphane as an intermediate in the preparation of pharmaceutically useful benzomorphane derivatives, in particular (-)-(1R,5S,2"R)-3'-hydroxy-2-(2-methoxypropyl)-5,9,9-trimethyl-6,7-benzo morphane
WO2001021259A2 (en) 1999-09-21 2001-03-29 Emory University Use and compositions for treating platelet-related disorders using anagrelide
US6495694B2 (en) * 2000-06-16 2002-12-17 Boehringer Ingelheim Pharma Kg Efficient separation of enantiomers of piperidone derivatives by precipitation of the desired eantiomer during in situ racemization of the unwanted enantiomer
AR091027A1 (es) 2012-05-11 2014-12-30 Purdue Pharma Lp Analogos de benzomorfano y el usos de estos
JP6400592B2 (ja) * 2012-11-09 2018-10-03 パーデュー、ファーマ、リミテッド、パートナーシップ ベンゾモルファン類似体およびその使用
WO2014118618A1 (en) 2013-01-31 2014-08-07 Purdue Pharma L.P. Benzomorphan analogs and the use thereof
CA2948144A1 (en) 2014-05-06 2015-11-12 Purdue Pharma L.P. Benzomorphan analogs and use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL130089C (fi) 1963-11-07
US4087532A (en) 1974-03-09 1978-05-02 Boehringer Ingelheim Gmbh Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof
GB1513961A (en) * 1975-02-25 1978-06-14 Acf Chemiefarma Nv 6,7-benzomorphans method for their preparation and intermediates
DE2716687A1 (de) 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
US4202897A (en) * 1977-07-25 1980-05-13 Sandoz, Inc. Prolactin secretion inhibitors
IT8049377A0 (it) 1979-08-03 1980-07-30 Sandoz Ag Medicamento a base di composti triciclici per inibire la secrezione dell'ormone luteinizzante(caso 1005224)

Also Published As

Publication number Publication date
AU6354080A (en) 1981-04-30
FI67373B (fi) 1984-11-30
US4425353A (en) 1984-01-10
ES8106894A1 (es) 1981-09-16
AU539310B2 (en) 1984-09-20
NL7907800A (nl) 1981-04-27
ES496167A0 (es) 1981-09-16
IE802188L (en) 1981-04-23
IE50667B1 (en) 1986-06-11
DE3068961D1 (en) 1984-09-20
CA1155840A (en) 1983-10-25
FI803237L (fi) 1981-04-24
ATE8990T1 (de) 1984-09-15
JPS5686164A (en) 1981-07-13
US4406904A (en) 1983-09-27
NZ195329A (en) 1984-05-31
EP0028717B1 (en) 1984-08-15
PT71949A (en) 1981-08-19
IL61324A0 (en) 1980-12-31
DK435380A (da) 1981-04-24
ZA806528B (en) 1982-06-30
IL61324A (en) 1985-03-31
EP0028717A1 (en) 1981-05-20
PT71949B (en) 1981-12-17
FI67373C (fi) 1985-03-11

Similar Documents

Publication Publication Date Title
DE3068961D1 (en) 6,7-benzomorphan derivatives, processes for their production, pharmaceutical compositions containing said derivatives and their use as pharmaceuticals
DE3065304D1 (en) Morpholine derivatives, pharmaceutical compositions containing them and processes for their preparation
DE69230163D1 (de) Thiazolylbenzofuranderivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten
ES487677A1 (es) Procedimiento para la preparacion de derivados de aril-ete- res
NZ214787A (en) Arylcyclobutylalkylamines and pharmaceutical compositions
ES482472A1 (es) Procedimiento para la preparacion de isoquinoleinas.
GB9215844D0 (en) Novel compounds
JPS5665869A (en) Novel 22hydroxyalkyll3*4*55trihydroxyypiperidine compound* its manufacture and drug
ES8500742A1 (es) Procedimiento para la preparacion de derivados de acido fenilacetico
ES8101074A1 (es) Procedimiento para la preparacion de derivados de xantina
ES8307734A1 (es) "procedimiento de producir derivados amidicos".
FI851456L (fi) Foerfarande foer framstaellning av 1-cyklohexyl-3,4-dihydroisokinolinderivat.
ES8406065A1 (es) Un procedimiento para la preparacion de derivados de trifluormetanosulfonanilida.
ES8200112A1 (es) Un procedimiento para la preparacion de un derivado del aci do clavulanico.
ES8105713A1 (es) Un procedimiento para la preparacion de los enatiomeros levogiro y dextrogiro de la 1-ciclopropil-metil-4-(3-metoxi-5h- dibenzo (a,d) ciclohepten-5-iliden) piperidina