FI803237L - 6,7-bensomorfanderivat foerfaranden foer deras framstaellning farmaceutiska sammansaettningar innehaollande naemnda derivat och deras anvaendning som laekemedel - Google Patents

6,7-bensomorfanderivat foerfaranden foer deras framstaellning farmaceutiska sammansaettningar innehaollande naemnda derivat och deras anvaendning som laekemedel

Info

Publication number
FI803237L
FI803237L FI803237A FI803237A FI803237L FI 803237 L FI803237 L FI 803237L FI 803237 A FI803237 A FI 803237A FI 803237 A FI803237 A FI 803237A FI 803237 L FI803237 L FI 803237L
Authority
FI
Finland
Prior art keywords
deras
bensomorfanderivat
naemnda
derivat
hydrogen
Prior art date
Application number
FI803237A
Other languages
English (en)
Other versions
FI67373B (fi
FI67373C (fi
Inventor
Antony Marie Akkerman
Bakel Hermanus C C K Van
Roelof C K Smit
Hendricus B A Welle
Magda Marko
Original Assignee
Acf Chemiefarma Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acf Chemiefarma Nv filed Critical Acf Chemiefarma Nv
Publication of FI803237L publication Critical patent/FI803237L/fi
Priority to FI833269A priority Critical patent/FI68226C/fi
Priority to FI833268A priority patent/FI68225C/fi
Priority to FI833267A priority patent/FI68224C/fi
Publication of FI67373B publication Critical patent/FI67373B/fi
Application granted granted Critical
Publication of FI67373C publication Critical patent/FI67373C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI803237A 1979-10-23 1980-10-14 Foerfarande foer framstaellning av 6,7-bensomorfanderivat vilka aer anvaendbara som analgetiska medel antagonister foer nakotiska medel och inhibitorer foer sekretion av det luten isrande hormonet FI67373C (fi)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FI833269A FI68226C (fi) 1979-10-23 1983-09-13 Foerfarande foer framstaellning av 6,7-benzomorfanderivat vilka aer anvaendbara som analgetiska aemnen antagonister foer narkotiska medel och inhibitorer foer sekretion av luteiniseringshormon
FI833268A FI68225C (fi) 1979-10-23 1983-09-13 Foerfarande foer framstaellning av 6,7-benzomorfanderivat vilka aer anvaendbara som analgetiska medel antagonister foer nakotiska medel och inhibitorer foer sekretion av luteinise rigshormon
FI833267A FI68224C (fi) 1979-10-23 1983-09-13 Foerfarande foer framstaellning av 6,7-benzomorfanderivat vilka aer anvaendbara som analgetiska aemnen antagonister foer narkotiska medel och inhibitorer foer sekretion av luteiniseringshormon

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL7907800A NL7907800A (nl) 1979-10-23 1979-10-23 Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan, farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werkwijze voor het bereiden van deze verbindingen en de farmaceutische preparaten.
NL7907800 1979-10-23

Publications (3)

Publication Number Publication Date
FI803237L true FI803237L (fi) 1981-04-24
FI67373B FI67373B (fi) 1984-11-30
FI67373C FI67373C (fi) 1985-03-11

Family

ID=19834064

Family Applications (1)

Application Number Title Priority Date Filing Date
FI803237A FI67373C (fi) 1979-10-23 1980-10-14 Foerfarande foer framstaellning av 6,7-bensomorfanderivat vilka aer anvaendbara som analgetiska medel antagonister foer nakotiska medel och inhibitorer foer sekretion av det luten isrande hormonet

Country Status (17)

Country Link
US (2) US4425353A (fi)
EP (1) EP0028717B1 (fi)
JP (1) JPS5686164A (fi)
AT (1) ATE8990T1 (fi)
AU (1) AU539310B2 (fi)
CA (1) CA1155840A (fi)
DE (1) DE3068961D1 (fi)
DK (1) DK435380A (fi)
ES (1) ES496167A0 (fi)
FI (1) FI67373C (fi)
IE (1) IE50667B1 (fi)
IL (1) IL61324A (fi)
MY (1) MY8700184A (fi)
NL (1) NL7907800A (fi)
NZ (1) NZ195329A (fi)
PT (1) PT71949B (fi)
ZA (1) ZA806528B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4579950A (en) * 1982-08-20 1986-04-01 Hoechst-Roussel Pharmaceuticals Inc. Intermediates for spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine] compounds
ZA887087B (en) * 1987-09-24 1989-06-28 Hoechst Roussel Pharma 2,6-methanopyrrolo-3-benzazocines,a process and intermediates for their preparation and their use as medicaments
DE4121821A1 (de) * 1991-07-02 1993-01-14 Boehringer Ingelheim Kg Neue benzomorphane und ihre verwendung als arzneimittel
DE19528472A1 (de) * 1995-08-03 1997-02-06 Boehringer Ingelheim Kg Neues Verfahren zur Herstellung von Norbenzomorphan einer Zwischenstufe bei Herstellung von pharmazeutisch wertvollen Benzomorphanderivaten, insbesondere von (-)-(1R,5S,S"R)-3'-Hydroxy-2-(2-methoxypropyl-)-5,9,9-trimethyl-6,7 benzomorphan
WO1999020223A2 (en) 1997-10-20 1999-04-29 Novo Nordisk A/S Luteinising hormone antagonists useful for treatment of estrogen deficiencies, or as a contraceptive
US6136980A (en) * 1998-05-01 2000-10-24 Boehringer Ingelheim Kg Method of preparing norbenzomorphane as an intermediate in the preparation of pharmaceutically useful benzomorphane derivatives, in particular (-)-(1R,5S,2"R)-3'-hydroxy-2-(2-methoxypropyl)-5,9,9-trimethyl-6,7-benzo morphane
WO2001021259A2 (en) 1999-09-21 2001-03-29 Emory University Use and compositions for treating platelet-related disorders using anagrelide
US6495694B2 (en) * 2000-06-16 2002-12-17 Boehringer Ingelheim Pharma Kg Efficient separation of enantiomers of piperidone derivatives by precipitation of the desired eantiomer during in situ racemization of the unwanted enantiomer
AR091027A1 (es) 2012-05-11 2014-12-30 Purdue Pharma Lp Analogos de benzomorfano y el usos de estos
JP6400592B2 (ja) * 2012-11-09 2018-10-03 パーデュー、ファーマ、リミテッド、パートナーシップ ベンゾモルファン類似体およびその使用
WO2014118618A1 (en) 2013-01-31 2014-08-07 Purdue Pharma L.P. Benzomorphan analogs and the use thereof
CA2948144A1 (en) 2014-05-06 2015-11-12 Purdue Pharma L.P. Benzomorphan analogs and use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL130089C (fi) 1963-11-07
US4087532A (en) 1974-03-09 1978-05-02 Boehringer Ingelheim Gmbh Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof
GB1513961A (en) * 1975-02-25 1978-06-14 Acf Chemiefarma Nv 6,7-benzomorphans method for their preparation and intermediates
DE2716687A1 (de) 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
US4202897A (en) * 1977-07-25 1980-05-13 Sandoz, Inc. Prolactin secretion inhibitors
IT8049377A0 (it) 1979-08-03 1980-07-30 Sandoz Ag Medicamento a base di composti triciclici per inibire la secrezione dell'ormone luteinizzante(caso 1005224)

Also Published As

Publication number Publication date
AU6354080A (en) 1981-04-30
FI67373B (fi) 1984-11-30
US4425353A (en) 1984-01-10
ES8106894A1 (es) 1981-09-16
AU539310B2 (en) 1984-09-20
NL7907800A (nl) 1981-04-27
ES496167A0 (es) 1981-09-16
IE802188L (en) 1981-04-23
IE50667B1 (en) 1986-06-11
DE3068961D1 (en) 1984-09-20
CA1155840A (en) 1983-10-25
ATE8990T1 (de) 1984-09-15
JPS5686164A (en) 1981-07-13
US4406904A (en) 1983-09-27
NZ195329A (en) 1984-05-31
MY8700184A (en) 1987-12-31
EP0028717B1 (en) 1984-08-15
PT71949A (en) 1981-08-19
IL61324A0 (en) 1980-12-31
DK435380A (da) 1981-04-24
ZA806528B (en) 1982-06-30
IL61324A (en) 1985-03-31
EP0028717A1 (en) 1981-05-20
PT71949B (en) 1981-12-17
FI67373C (fi) 1985-03-11

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: ACF CHEMIEFARMA NV