DK435380A - Fremgangsmaade til fremstilling af benzomorphanderivater - Google Patents

Fremgangsmaade til fremstilling af benzomorphanderivater

Info

Publication number
DK435380A
DK435380A DK435380A DK435380A DK435380A DK 435380 A DK435380 A DK 435380A DK 435380 A DK435380 A DK 435380A DK 435380 A DK435380 A DK 435380A DK 435380 A DK435380 A DK 435380A
Authority
DK
Denmark
Prior art keywords
hydrogen
optionally
alkyl
derivatives
hydroxy
Prior art date
Application number
DK435380A
Other languages
Danish (da)
English (en)
Inventor
A M Akkerman
H C C K V Bakel
R C K Smit
H B A Welle
M Marko
Original Assignee
Acf Chemiefarma Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acf Chemiefarma Nv filed Critical Acf Chemiefarma Nv
Publication of DK435380A publication Critical patent/DK435380A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK435380A 1979-10-23 1980-10-14 Fremgangsmaade til fremstilling af benzomorphanderivater DK435380A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7907800A NL7907800A (nl) 1979-10-23 1979-10-23 Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan, farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werkwijze voor het bereiden van deze verbindingen en de farmaceutische preparaten.

Publications (1)

Publication Number Publication Date
DK435380A true DK435380A (da) 1981-04-24

Family

ID=19834064

Family Applications (1)

Application Number Title Priority Date Filing Date
DK435380A DK435380A (da) 1979-10-23 1980-10-14 Fremgangsmaade til fremstilling af benzomorphanderivater

Country Status (17)

Country Link
US (2) US4425353A (fi)
EP (1) EP0028717B1 (fi)
JP (1) JPS5686164A (fi)
AT (1) ATE8990T1 (fi)
AU (1) AU539310B2 (fi)
CA (1) CA1155840A (fi)
DE (1) DE3068961D1 (fi)
DK (1) DK435380A (fi)
ES (1) ES496167A0 (fi)
FI (1) FI67373C (fi)
IE (1) IE50667B1 (fi)
IL (1) IL61324A (fi)
MY (1) MY8700184A (fi)
NL (1) NL7907800A (fi)
NZ (1) NZ195329A (fi)
PT (1) PT71949B (fi)
ZA (1) ZA806528B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4579950A (en) * 1982-08-20 1986-04-01 Hoechst-Roussel Pharmaceuticals Inc. Intermediates for spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine] compounds
ZA887087B (en) * 1987-09-24 1989-06-28 Hoechst Roussel Pharma 2,6-methanopyrrolo-3-benzazocines,a process and intermediates for their preparation and their use as medicaments
DE4121821A1 (de) * 1991-07-02 1993-01-14 Boehringer Ingelheim Kg Neue benzomorphane und ihre verwendung als arzneimittel
DE19528472A1 (de) * 1995-08-03 1997-02-06 Boehringer Ingelheim Kg Neues Verfahren zur Herstellung von Norbenzomorphan einer Zwischenstufe bei Herstellung von pharmazeutisch wertvollen Benzomorphanderivaten, insbesondere von (-)-(1R,5S,S"R)-3'-Hydroxy-2-(2-methoxypropyl-)-5,9,9-trimethyl-6,7 benzomorphan
WO1999020223A2 (en) 1997-10-20 1999-04-29 Novo Nordisk A/S Luteinising hormone antagonists useful for treatment of estrogen deficiencies, or as a contraceptive
US6136980A (en) * 1998-05-01 2000-10-24 Boehringer Ingelheim Kg Method of preparing norbenzomorphane as an intermediate in the preparation of pharmaceutically useful benzomorphane derivatives, in particular (-)-(1R,5S,2"R)-3'-hydroxy-2-(2-methoxypropyl)-5,9,9-trimethyl-6,7-benzo morphane
WO2001021259A2 (en) 1999-09-21 2001-03-29 Emory University Use and compositions for treating platelet-related disorders using anagrelide
US6495694B2 (en) * 2000-06-16 2002-12-17 Boehringer Ingelheim Pharma Kg Efficient separation of enantiomers of piperidone derivatives by precipitation of the desired eantiomer during in situ racemization of the unwanted enantiomer
AR091027A1 (es) 2012-05-11 2014-12-30 Purdue Pharma Lp Analogos de benzomorfano y el usos de estos
JP6400592B2 (ja) * 2012-11-09 2018-10-03 パーデュー、ファーマ、リミテッド、パートナーシップ ベンゾモルファン類似体およびその使用
WO2014118618A1 (en) 2013-01-31 2014-08-07 Purdue Pharma L.P. Benzomorphan analogs and the use thereof
CA2948144A1 (en) 2014-05-06 2015-11-12 Purdue Pharma L.P. Benzomorphan analogs and use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL130089C (fi) 1963-11-07
US4087532A (en) 1974-03-09 1978-05-02 Boehringer Ingelheim Gmbh Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof
GB1513961A (en) * 1975-02-25 1978-06-14 Acf Chemiefarma Nv 6,7-benzomorphans method for their preparation and intermediates
DE2716687A1 (de) 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
US4202897A (en) * 1977-07-25 1980-05-13 Sandoz, Inc. Prolactin secretion inhibitors
IT8049377A0 (it) 1979-08-03 1980-07-30 Sandoz Ag Medicamento a base di composti triciclici per inibire la secrezione dell'ormone luteinizzante(caso 1005224)

Also Published As

Publication number Publication date
AU6354080A (en) 1981-04-30
FI67373B (fi) 1984-11-30
US4425353A (en) 1984-01-10
ES8106894A1 (es) 1981-09-16
AU539310B2 (en) 1984-09-20
NL7907800A (nl) 1981-04-27
ES496167A0 (es) 1981-09-16
IE802188L (en) 1981-04-23
IE50667B1 (en) 1986-06-11
DE3068961D1 (en) 1984-09-20
CA1155840A (en) 1983-10-25
FI803237L (fi) 1981-04-24
ATE8990T1 (de) 1984-09-15
JPS5686164A (en) 1981-07-13
US4406904A (en) 1983-09-27
NZ195329A (en) 1984-05-31
MY8700184A (en) 1987-12-31
EP0028717B1 (en) 1984-08-15
PT71949A (en) 1981-08-19
IL61324A0 (en) 1980-12-31
ZA806528B (en) 1982-06-30
IL61324A (en) 1985-03-31
EP0028717A1 (en) 1981-05-20
PT71949B (en) 1981-12-17
FI67373C (fi) 1985-03-11

Similar Documents

Publication Publication Date Title
SE8200916L (sv) Karbostyrilderivat, forfarande for framstellning derav och hjertsterkande komposition som innehaller detsamma
HRP20000896B1 (en) Adenosine derivatives
MX9300498A (es) Derivados de n-sulfonil-2-oxo-indol, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
DK435380A (da) Fremgangsmaade til fremstilling af benzomorphanderivater
BR1100931A (pt) Compostos derivados de aril-heteroaril carbinóis, processos para a preparação dos compostos, composições farmacêuticas, e, uso dos compostos derivados de aril-heteroaril carbinóis
DE3065304D1 (en) Morpholine derivatives, pharmaceutical compositions containing them and processes for their preparation
ES2084129T3 (es) Nuevas calconas heterociclicas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.
AU529663B2 (en) Piperidine alkyl ethers of coumarin and quinoline
ES2122258T3 (es) 4-azaesteroides 15 sustituidos.
NO800447L (no) Derivater av difenylhydantoin, farmasoeytiske preparater inneholdende slike preparater, samt fremgangsmaate til fremstilling av de aktive forbindelser
ES557445A0 (es) Un procedimiento para preparar derivados de arilciclobutilalquilamina
MX9304467A (es) Nuevos derivados fosfonados de ariletanolaminas, procedimiento para su preparacion y composiciones farmaceuticas y veterinarias que los contienen.
MX9203939A (es) Derivados de hidroisoquinolina y composiciones farmaceuticas que los contienen.
SE8006953L (sv) Heterocykliska foreningar
DK435583A (da) Fremgangsmaade til fremstilling af heterocykliske derivater af cyklobutan
ATE24310T1 (de) Phlorophenon-derivate, verfahren zur herstellung solcher verbindungen, verwendung und pharmazeutische zusammensetzungen der phlorophenon-verbindungen.
ATE238055T1 (de) Chinazolinon enthaltende arzneimittel und verfahren zu deren verwendung
IL60176A (en) (aminopiperidinopropyl)dimethyl xanthine derivatives,processes for the preparation thereof and pharmaceutical compositions containing them
NZ217276A (en) Bicyclic heterocyclic compounds and pharmaceutical compositions
ES8406065A1 (es) Un procedimiento para la preparacion de derivados de trifluormetanosulfonanilida.
ES2052206T3 (es) Procedimiento de preparacion de nuevos derivados de benzotiazolinona y las composiciones farmaceuticas que los contienen.
BR8306505A (pt) Compostos,processo para preparacao dos mesmos,medicamento e uso de tais compostos

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment