MY185764A - Microorganism producing o-acetyl homoserine and the method of producing o-acetyl homoserine using the same - Google Patents

Microorganism producing o-acetyl homoserine and the method of producing o-acetyl homoserine using the same

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Publication number
MY185764A
MY185764A MYPI2015002962A MYPI2015002962A MY185764A MY 185764 A MY185764 A MY 185764A MY PI2015002962 A MYPI2015002962 A MY PI2015002962A MY PI2015002962 A MYPI2015002962 A MY PI2015002962A MY 185764 A MY185764 A MY 185764A
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MY
Malaysia
Prior art keywords
producing
acetyl homoserine
same
microorganism
homoserine
Prior art date
Application number
MYPI2015002962A
Other languages
English (en)
Inventor
Hyun Ah Kim
Ju Hee Seo
Yong Uk Shin
So Young Kim
Sang Kyoum Kim
Kwang Ho Na
Jee Yeon Bae
Sung Kwang Son
Hye Ryun Yoo
Jin Geun Choi
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of MY185764A publication Critical patent/MY185764A/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01031Homoserine O-acetyltransferase (2.3.1.31)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/06Alanine; Leucine; Isoleucine; Serine; Homoserine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/12Methionine; Cysteine; Cystine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/03Acyl groups converted into alkyl on transfer (2.3.3)
    • C12Y203/03001Citrate (Si)-synthase (2.3.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/01039Homoserine kinase (2.7.1.39)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y401/00Carbon-carbon lyases (4.1)
    • C12Y401/01Carboxy-lyases (4.1.1)
    • C12Y401/01031Phosphoenolpyruvate carboxylase (4.1.1.31)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/02Cells for production
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185Escherichia

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
MYPI2015002962A 2014-06-23 2015-06-22 Microorganism producing o-acetyl homoserine and the method of producing o-acetyl homoserine using the same MY185764A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020140076779A KR101641770B1 (ko) 2014-06-23 2014-06-23 O-아세틸 호모세린을 생산하는 미생물 및 상기 미생물을 이용하여 o-아세틸 호모세린을 생산하는 방법
PCT/KR2015/006307 WO2015199396A1 (ko) 2014-06-23 2015-06-22 O-아세틸 호모세린을 생산하는 미생물 및 상기 미생물을 이용하여 o-아세틸 호모세린을 생산하는 방법

Publications (1)

Publication Number Publication Date
MY185764A true MY185764A (en) 2021-06-04

Family

ID=54938419

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2015002962A MY185764A (en) 2014-06-23 2015-06-22 Microorganism producing o-acetyl homoserine and the method of producing o-acetyl homoserine using the same

Country Status (14)

Country Link
US (2) US10465217B2 (https=)
EP (2) EP2998388B1 (https=)
JP (2) JP6336074B2 (https=)
KR (1) KR101641770B1 (https=)
CN (2) CN105392880B (https=)
AU (1) AU2015264911B2 (https=)
BR (2) BR122020005905B1 (https=)
DK (1) DK2998388T3 (https=)
ES (1) ES2833432T3 (https=)
MY (1) MY185764A (https=)
PL (1) PL2998388T3 (https=)
RU (1) RU2614253C1 (https=)
SG (1) SG11201509451WA (https=)
WO (1) WO2015199396A1 (https=)

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CN111315877B (zh) * 2017-06-30 2023-08-08 Cj第一制糖株式会社 新型o-琥珀酰高丝氨酸转移酶变体及使用其生产o-琥珀酰高丝氨酸的方法
CN110129294B (zh) * 2018-02-02 2021-12-24 中国科学院天津工业生物技术研究所 高丝氨酸乙酰基转移酶突变体及其宿主细胞和应用
KR101915433B1 (ko) 2018-02-13 2018-11-05 씨제이제일제당 (주) 시트레이트 신타아제 (Citrate synthase)의 활성이 약화된 변이형 폴리펩타이드 및 이를 이용한 L-아미노산 생산방법
CN113122486B (zh) * 2019-12-31 2023-06-13 江南大学 一种丙二酸的全生物合成的方法
KR102285951B1 (ko) 2020-01-30 2021-08-04 씨제이제일제당 주식회사 시트레이트 신타아제의 활성이 약화된 신규한 변이형 폴리펩티드 및 이를 이용한 l-아미노산 생산 방법
CN115427580A (zh) * 2020-02-07 2022-12-02 代谢探索者公司 用于改善依克多因产生的经修饰的微生物和方法
KR102344689B1 (ko) * 2020-09-01 2021-12-29 씨제이제일제당 주식회사 L-발린 생산 미생물 및 이를 이용한 l-발린 생산 방법
CN112501144B (zh) * 2021-02-02 2021-04-20 中国科学院天津工业生物技术研究所 高丝氨酸乙酰转移酶突变体及其在生产o-乙酰高丝氨酸中的应用
KR102525073B1 (ko) * 2021-03-10 2023-04-24 씨제이제일제당 주식회사 신규한 시트레이트 신타아제 변이체 및 이를 이용한 l-발린 생산 방법
KR102525074B1 (ko) * 2021-03-10 2023-04-24 씨제이제일제당 주식회사 신규한 시트레이트 신타아제 변이체 및 이를 이용한 o-아세틸-l-호모세린 또는 l-메티오닌 생산 방법
KR102525072B1 (ko) * 2021-03-10 2023-04-24 씨제이제일제당 주식회사 신규한 시트레이트 신타아제 변이체 및 이를 이용한 l-아미노산 생산 방법
CN113388564B (zh) * 2021-06-04 2022-03-01 浙江工业大学 一种o-乙酰-l-高丝氨酸生产菌、构建方法及应用
KR102952497B1 (ko) * 2022-03-28 2026-04-15 씨제이제일제당 주식회사 O-아세틸 호모세린 생산 미생물 및 이를 이용한 o-아세틸 호모세린 또는 l-메치오닌 생산 방법
KR20230139598A (ko) * 2022-03-28 2023-10-05 씨제이제일제당 (주) O-아세틸 호모세린 생산 미생물 및 이를 이용한 o-아세틸 호모세린 또는 l-메치오닌 생산 방법
KR20240147322A (ko) 2023-03-31 2024-10-08 씨제이제일제당 (주) 미생물 발효를 활용한 o-아세틸 호모세린 제조 공정

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RU2010101135A (ru) * 2010-01-15 2011-07-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) (RU) Бактерия семейства enterobacteriaceae - продуцент l-аспартата или метаболитов, производных l-аспартата, и способ получения l-аспартата или метаболитов, производных l-аспартата
JP5758499B2 (ja) 2010-12-21 2015-08-05 シージェイ チェイルジェダン コーポレイション ホモセリンアセチルトランスフェラーゼ活性を有する変異型ポリペプチド及びそれを発現する微生物

Also Published As

Publication number Publication date
AU2015264911B2 (en) 2017-11-23
PL2998388T3 (pl) 2021-05-17
JP6607974B2 (ja) 2019-11-20
KR101641770B1 (ko) 2016-07-22
BR122020005905B1 (pt) 2022-07-26
BR112015029716A2 (pt) 2017-09-26
EP3783096B1 (en) 2024-03-13
KR20160000098A (ko) 2016-01-04
RU2614253C1 (ru) 2017-03-24
EP2998388A4 (en) 2017-03-22
SG11201509451WA (en) 2016-01-28
CN105392880A (zh) 2016-03-09
EP2998388B1 (en) 2020-10-07
JP6336074B2 (ja) 2018-06-06
BR112015029716B1 (pt) 2022-07-19
JP2018046875A (ja) 2018-03-29
EP2998388A1 (en) 2016-03-23
US10815509B2 (en) 2020-10-27
CN105392880B (zh) 2019-11-08
DK2998388T3 (da) 2020-11-23
AU2015264911A1 (en) 2016-01-21
US20170101655A1 (en) 2017-04-13
ES2833432T3 (es) 2021-06-15
CN110592153A (zh) 2019-12-20
WO2015199396A1 (ko) 2015-12-30
US20200024626A1 (en) 2020-01-23
EP3783096A1 (en) 2021-02-24
JP2016526927A (ja) 2016-09-08
US10465217B2 (en) 2019-11-05

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