MY158100A - 6,9-disubstituted purine derivatives and their use for treating skin - Google Patents
6,9-disubstituted purine derivatives and their use for treating skinInfo
- Publication number
- MY158100A MY158100A MYPI20090112A MYPI20090112A MY158100A MY 158100 A MY158100 A MY 158100A MY PI20090112 A MYPI20090112 A MY PI20090112A MY PI20090112 A MYPI20090112 A MY PI20090112A MY 158100 A MY158100 A MY 158100A
- Authority
- MY
- Malaysia
- Prior art keywords
- purine derivatives
- treating skin
- disubstituted purine
- human skin
- disubstituted
- Prior art date
Links
- -1 6,9-disubstituted purine Chemical class 0.000 title abstract 2
- 229940083251 peripheral vasodilators purine derivative Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 230000002411 adverse Effects 0.000 abstract 1
- 230000032683 aging Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000003463 hyperproliferative effect Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 abstract 1
- 210000004927 skin cell Anatomy 0.000 abstract 1
- 208000017520 skin disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80687106P | 2006-07-10 | 2006-07-10 | |
| US11/774,652 US20080009508A1 (en) | 2006-07-10 | 2007-07-09 | 6,9-Disubstituted Purine Derivatives And Their Use For Treating Skin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY158100A true MY158100A (en) | 2016-08-30 |
Family
ID=38919793
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI20090112A MY158100A (en) | 2006-07-10 | 2007-07-10 | 6,9-disubstituted purine derivatives and their use for treating skin |
Country Status (16)
| Country | Link |
|---|---|
| US (4) | US20080009508A1 (OSRAM) |
| EP (1) | EP2043630B1 (OSRAM) |
| JP (1) | JP5309023B2 (OSRAM) |
| KR (1) | KR101478727B1 (OSRAM) |
| CN (1) | CN101646435B (OSRAM) |
| AU (1) | AU2007272576B2 (OSRAM) |
| BR (1) | BRPI0714161A2 (OSRAM) |
| CA (1) | CA2657516C (OSRAM) |
| EA (1) | EA015848B1 (OSRAM) |
| ES (1) | ES2603216T3 (OSRAM) |
| IL (1) | IL196442A (OSRAM) |
| MX (1) | MX2009000347A (OSRAM) |
| MY (1) | MY158100A (OSRAM) |
| NO (1) | NO20090598L (OSRAM) |
| NZ (1) | NZ574711A (OSRAM) |
| WO (1) | WO2008008770A2 (OSRAM) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7960397B2 (en) * | 2007-12-28 | 2011-06-14 | Institute Of Experimental Botany, Academy Of Sciences Of The Czech Republic | 6,9-disubstituted purine derivatives and their use as cosmetics and cosmetic compositions |
| EP2448938B9 (en) | 2009-06-29 | 2015-06-10 | Incyte Corporation | Pyrimidinones as pi3k inhibitors |
| US8759359B2 (en) * | 2009-12-18 | 2014-06-24 | Incyte Corporation | Substituted heteroaryl fused derivatives as PI3K inhibitors |
| TW201130842A (en) * | 2009-12-18 | 2011-09-16 | Incyte Corp | Substituted fused aryl and heteroaryl derivatives as PI3K inhibitors |
| AR081823A1 (es) | 2010-04-14 | 2012-10-24 | Incyte Corp | DERIVADOS FUSIONADOS COMO INHIBIDORES DE PI3Kd |
| US9096852B2 (en) | 2010-06-09 | 2015-08-04 | Chanel Parfums Beaute | Inhibitors of micro-RNAs for use for preventing and/or attenuating skin ageing and/or for hydrating skin |
| EP2395086A1 (en) * | 2010-06-09 | 2011-12-14 | Chanel Parfums Beauté | Inhibitors of micro-RNAs for use for preventing and/or attenuating skin ageing and/or for hydrating skin |
| US9062055B2 (en) | 2010-06-21 | 2015-06-23 | Incyte Corporation | Fused pyrrole derivatives as PI3K inhibitors |
| EP2655374B1 (en) | 2010-12-20 | 2019-10-23 | Incyte Holdings Corporation | N-(1-(substituted-phenyl)ethyl)-9h-purin-6-amines as pi3k inhibitors |
| US9108984B2 (en) | 2011-03-14 | 2015-08-18 | Incyte Corporation | Substituted diamino-pyrimidine and diamino-pyridine derivatives as PI3K inhibitors |
| US9126948B2 (en) | 2011-03-25 | 2015-09-08 | Incyte Holdings Corporation | Pyrimidine-4,6-diamine derivatives as PI3K inhibitors |
| PL3513793T3 (pl) | 2011-09-02 | 2021-09-20 | Incyte Holdings Corporation | Heterocykloaminy jako inhibitory pi3k |
| US20130072506A1 (en) | 2011-09-16 | 2013-03-21 | Lenka ZAHAJSKA | 6,8-disubstituted purine compositions |
| AR090548A1 (es) | 2012-04-02 | 2014-11-19 | Incyte Corp | Azaheterociclobencilaminas biciclicas como inhibidores de pi3k |
| WO2015191677A1 (en) | 2014-06-11 | 2015-12-17 | Incyte Corporation | Bicyclic heteroarylaminoalkyl phenyl derivatives as pi3k inhibitors |
| CZ306984B6 (cs) * | 2014-12-15 | 2017-11-01 | Ústav experimentální botaniky AV ČR, v. v. i. | 6,8-Disubstituované-9-(heterocyklyl)puriny, přípravky obsahující tyto deriváty a jejich použití v kosmetických a medicínských aplikacích |
| RS63963B1 (sr) | 2015-02-27 | 2023-03-31 | Incyte Holdings Corp | Postupak pripreme pi3k inhibitora |
| WO2016183063A1 (en) | 2015-05-11 | 2016-11-17 | Incyte Corporation | Crystalline forms of a pi3k inhibitor |
| US9732097B2 (en) | 2015-05-11 | 2017-08-15 | Incyte Corporation | Process for the synthesis of a phosphoinositide 3-kinase inhibitor |
| CZ307722B6 (cs) * | 2015-08-28 | 2019-03-27 | Univerzita PalackĂ©ho v Olomouci | Adeninové deriváty a jejich použití |
| CZ307868B6 (cs) * | 2017-04-28 | 2019-07-10 | Univerzita PalackĂ©ho v Olomouci | Deriváty 9-(2-oxacykloalkyl)-9H-purin-2,6-diaminu, přípravky obsahující tyto deriváty a jejich použití |
| AU2019277560B2 (en) | 2018-06-01 | 2025-04-24 | Incyte Corporation | Dosing regimen for the treatment of PI3K related disorders |
| EP4178959B1 (en) | 2020-07-13 | 2025-09-10 | Univerzita Palackého v Olomouci | Nitrogen heterocyclic cytokinin derivatives, compositions containing these derivatives and use thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5371089A (en) * | 1987-02-26 | 1994-12-06 | Senetek, Plc | Method and composition for ameliorating the adverse effects of aging |
| US5021422A (en) * | 1989-06-08 | 1991-06-04 | Senetek Plc | Method and composition for treating hyperproliferative skin diseases using 6-aminopurine cytokinins |
| AU2003274652A1 (en) * | 2002-10-23 | 2004-05-13 | Obetherapy Biotechnology | Compounds, compositions and methods for modulating fat metabolism |
| US7138402B2 (en) * | 2003-09-18 | 2006-11-21 | Conforma Therapeutics Corporation | Pyrrolopyrimidines and related analogs as HSP90-inhibitors |
| EP1901817A2 (en) * | 2005-07-08 | 2008-03-26 | The Procter and Gamble Company | Personal care compositions and methods for the beautification of mammalian skin and hair |
-
2007
- 2007-07-09 US US11/774,652 patent/US20080009508A1/en not_active Abandoned
- 2007-07-10 EA EA200970110A patent/EA015848B1/ru not_active IP Right Cessation
- 2007-07-10 ES ES07799439.0T patent/ES2603216T3/es active Active
- 2007-07-10 AU AU2007272576A patent/AU2007272576B2/en not_active Ceased
- 2007-07-10 NZ NZ574711A patent/NZ574711A/en not_active IP Right Cessation
- 2007-07-10 MY MYPI20090112A patent/MY158100A/en unknown
- 2007-07-10 EP EP07799439.0A patent/EP2043630B1/en not_active Not-in-force
- 2007-07-10 JP JP2009519632A patent/JP5309023B2/ja not_active Expired - Fee Related
- 2007-07-10 MX MX2009000347A patent/MX2009000347A/es not_active Application Discontinuation
- 2007-07-10 CA CA2657516A patent/CA2657516C/en not_active Expired - Fee Related
- 2007-07-10 CN CN200780031839XA patent/CN101646435B/zh not_active Expired - Fee Related
- 2007-07-10 KR KR1020097002557A patent/KR101478727B1/ko not_active Expired - Fee Related
- 2007-07-10 BR BRPI0714161-0A patent/BRPI0714161A2/pt not_active IP Right Cessation
- 2007-07-10 WO PCT/US2007/073142 patent/WO2008008770A2/en not_active Ceased
-
2009
- 2009-01-11 IL IL196442A patent/IL196442A/en active IP Right Grant
- 2009-02-06 NO NO20090598A patent/NO20090598L/no not_active Application Discontinuation
-
2010
- 2010-05-24 US US12/786,027 patent/US20100234401A1/en not_active Abandoned
-
2011
- 2011-05-26 US US13/116,636 patent/US20110224238A1/en not_active Abandoned
-
2012
- 2012-09-28 US US13/630,673 patent/US20130072505A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL196442A0 (en) | 2009-11-18 |
| EP2043630A4 (en) | 2010-12-29 |
| WO2008008770A2 (en) | 2008-01-17 |
| CN101646435A (zh) | 2010-02-10 |
| ES2603216T3 (es) | 2017-02-24 |
| CA2657516C (en) | 2016-05-10 |
| MX2009000347A (es) | 2009-03-20 |
| US20080009508A1 (en) | 2008-01-10 |
| KR101478727B1 (ko) | 2015-01-02 |
| BRPI0714161A2 (pt) | 2012-12-25 |
| CA2657516A1 (en) | 2008-01-17 |
| US20100234401A1 (en) | 2010-09-16 |
| AU2007272576B2 (en) | 2012-05-17 |
| EP2043630B1 (en) | 2016-09-07 |
| IL196442A (en) | 2015-10-29 |
| NO20090598L (no) | 2009-04-14 |
| US20130072505A1 (en) | 2013-03-21 |
| WO2008008770A3 (en) | 2008-04-10 |
| EA015848B1 (ru) | 2011-12-30 |
| EA200970110A1 (ru) | 2009-06-30 |
| NZ574711A (en) | 2012-05-25 |
| KR20090047457A (ko) | 2009-05-12 |
| EP2043630A2 (en) | 2009-04-08 |
| AU2007272576A1 (en) | 2008-01-17 |
| JP5309023B2 (ja) | 2013-10-09 |
| US20110224238A1 (en) | 2011-09-15 |
| CN101646435B (zh) | 2012-08-22 |
| JP2009543799A (ja) | 2009-12-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MY158100A (en) | 6,9-disubstituted purine derivatives and their use for treating skin | |
| MY151018A (en) | Use of nutritional compositions for preventing disorders | |
| MX2010004074A (es) | Combinacion 059. | |
| CY1120115T1 (el) | Προερχομενα απο μυελο των οστων μεσεγχυματικα αρχεγονα κυτταρα ως μια πηγη νευρικων προγονων | |
| MY176679A (en) | Use of nutritional compositions for preventing disorders | |
| LUC00011I2 (OSRAM) | ||
| MX2007007032A (es) | Compuestos de aminopirimidina y metodos de uso. | |
| MY149957A (en) | Heterocyclic inhibitors of mek and methods of use thereof | |
| MX2007004551A (es) | Compuestos tiadiazol y metodos de uso. | |
| TW200738657A (en) | Thiazole compounds and methods of use | |
| ZA200702322B (en) | Compositions and methods for the diagnosis and treatment of tumor | |
| WO2009086457A3 (en) | 6,9-disubstituted purine derivatives and their use as cosmetics and cosmetic compositions | |
| EP1670450A4 (en) | PHARMACEUTICAL COMPOSITIONS AND METHOD OF USING LEVODOPA AND CARBIDOPA | |
| CL2011000119A1 (es) | Compuestos derivados de triazolo[4,3-a]piridina; procedimiento de preparacion; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como cancer. | |
| CY1118073T1 (el) | Συνθεσεις και μεθοδοι για την αυξηση της δρασης της τελομερασης | |
| ECSP10010196A (es) | Derivados de amidas del ácido 6,7-dihidro-5h-imidazo[1,2-a]imidazol-3-carboxílico | |
| TW200716224A (en) | Method of indentifying therapeutic targets for the treatment of vulvovaginal atrophy | |
| GB0416508D0 (en) | Therapeutic agents | |
| ZA201000581B (en) | 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-6-carboxamide and 2,3,4,5-tetrahydropyrrolo[1,2-a][1,4]-diazepine-7-carboxamide derivatives,preparation and therapeutic use thereof | |
| EP2294197A4 (en) | HHIP1 PROTEIN VERSION AND METHOD AND USES THEREOF | |
| TW200738752A (en) | Modulation of MDL-1 activity for treatment of inflammatory disease | |
| WO2006032054A3 (en) | Differentiation of human mesenchymal stem cells to cardiac progenitor cells that promote cardiac repair | |
| WO2009134396A3 (en) | Use of corticotropin-releasing factor for the treatment of cancer | |
| UA37688U (ru) | Способ лечения больных с циррозом печени и профилактики его осложнений | |
| TW200615000A (en) | Use of arginase for the treatment of hepatitis |