MY148252A - 6-cyclymethyl-and 6-alkylmethyl-substituted pyrazolopyrimidines - Google Patents
6-cyclymethyl-and 6-alkylmethyl-substituted pyrazolopyrimidinesInfo
- Publication number
- MY148252A MY148252A MYPI20041687A MYPI20041687A MY148252A MY 148252 A MY148252 A MY 148252A MY PI20041687 A MYPI20041687 A MY PI20041687A MY PI20041687 A MYPI20041687 A MY PI20041687A MY 148252 A MY148252 A MY 148252A
- Authority
- MY
- Malaysia
- Prior art keywords
- alkylmethyl
- cyclymethyl
- substituted pyrazolopyrimidines
- pyrazolopyrimidines
- substituted
- Prior art date
Links
- APXRHPDHORGIEB-UHFFFAOYSA-N 1H-pyrazolo[4,3-d]pyrimidine Chemical class N1=CN=C2C=NNC2=C1 APXRHPDHORGIEB-UHFFFAOYSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000008447 perception Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10320784 | 2003-05-09 | ||
| DE10336183 | 2003-08-07 | ||
| DE102004004142A DE102004004142A1 (de) | 2003-05-09 | 2004-01-28 | 6-Cyclylmethyl- und 6-Alkylmethyl-substituierte Pyrazolopyrimidine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY148252A true MY148252A (en) | 2013-03-29 |
Family
ID=33420016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI20041687A MY148252A (en) | 2003-05-09 | 2004-05-07 | 6-cyclymethyl-and 6-alkylmethyl-substituted pyrazolopyrimidines |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP2298773B1 (enExample) |
| JP (1) | JP5277303B2 (enExample) |
| CL (1) | CL2004000978A1 (enExample) |
| DE (1) | DE102004004142A1 (enExample) |
| MY (1) | MY148252A (enExample) |
| NZ (1) | NZ543812A (enExample) |
| PE (1) | PE20050201A1 (enExample) |
| RU (1) | RU2383546C2 (enExample) |
| TW (1) | TWI350836B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6244353B2 (ja) * | 2013-04-05 | 2017-12-06 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ピリジニルピラゾロキノリン化合物 |
| KR20200010220A (ko) | 2017-06-01 | 2020-01-30 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 피라졸로퀴놀린 유도체를 함유하는 루이소체 질병 치료제 |
| KR20200010211A (ko) | 2017-06-01 | 2020-01-30 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | Pde9 저해제를 포함하는 약제학적 조성물 |
| RU2019135834A (ru) | 2017-06-01 | 2021-07-13 | Эйсай Ар Энд Ди Менеджмент Ко., Лтд. | Терапевтическое средство для лечения деменции, представляющее собой комбинацию производного пиразолохинолина и донепезила |
| SG10202113199RA (en) | 2017-06-01 | 2021-12-30 | Eisai R&D Man Co Ltd | Dementia therapeutic agent combining pyrazoloquinoline derivative and memantine |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1147234B (de) | 1960-05-11 | 1963-04-18 | Ciba Geigy | Verfahren zur Herstellung von 1-Isopropyl-4-hydroxy-6-benzyl-pyrazolo[3, 4-d]pyrimidin |
| CH396924A (de) | 1960-05-11 | 1965-08-15 | Ciba Geigy | Verfahren zur Herstellung von 4-Mercapto-pyrazolo(3,4-d)pyrimidinen |
| CH396927A (de) | 1960-05-11 | 1965-08-15 | Ciba Geigy | Verfahren zur Herstellung neuer Pyrazolopyrimidine |
| CH396925A (de) * | 1960-05-11 | 1965-08-15 | Ciba Geigy | Verfahren zur Herstellung neuer Pyrazolopyrimidine |
| DE1161281B (de) | 1960-05-11 | 1964-01-16 | Ciba Aktiengesellschaft, Basel (Schweiz) | Verfahren zur Herstellung von 1-Alkyl-6-aralkyl-pyrazoloÄ3,4-dÜ-pyrimidinen. |
| DE1149013B (de) | 1960-05-11 | 1963-05-22 | Ciba Geigy | Verfahren zur Herstellung von 4-Oxo-4, 5-dihydro-pyrazolo-[3, 4-d]Pyrimidinen |
| CH396926A (de) | 1960-05-11 | 1965-08-15 | Ciba Geigy | Verfahren zur Herstellung neuer Pyrazolopyrimidine |
| US3732225A (en) | 1970-07-23 | 1973-05-08 | Squibb & Sons Inc | Pyrazolo(3,4-d)pyrimidine derivatives |
| US3847908A (en) | 1973-03-05 | 1974-11-12 | Squibb & Sons Inc | 6-styrylpyrazolo(3,4-d)pyrimidinones and pyrimidines |
| DE59009485D1 (de) | 1989-01-26 | 1995-09-14 | Bayer Ag | Optisch aktive (Meth)Acrylsäure-Derivate, ihre Herstellung, ihre Polymerisation zu optisch aktiven Polymeren und deren Verwendung. |
| RU2104216C1 (ru) * | 1994-01-10 | 1998-02-10 | Акционерное общество открытого типа "Таганрогский авиационный научно-технический комплекс им.Г.М.Бериева" | Замок |
| DE19709877A1 (de) | 1997-03-11 | 1998-09-17 | Bayer Ag | 1,5-Dihydro-pyrazolo[3,4-d]-pyrimidinon-derivate |
| EP1307201B1 (de) * | 2000-08-01 | 2004-11-24 | Bayer HealthCare AG | Selektive pde 2-inhibitoren als arzneimittel zur verbesserung der wahrnehmung |
| JP2005508978A (ja) * | 2001-11-02 | 2005-04-07 | ファイザー・プロダクツ・インク | Pde9阻害薬によるインスリン抵抗性症候群及び2型糖尿病の治療 |
| HN2002000317A (es) * | 2001-11-02 | 2003-05-21 | Pfizer | Inhibidores de pde9 para tratamiento de trastornos cardiovasculares |
| DE10219435A1 (de) * | 2002-05-02 | 2003-11-13 | Bayer Cropscience Ag | Substituierte Pyrazolo-pyrimidin-4-one |
-
2004
- 2004-01-28 DE DE102004004142A patent/DE102004004142A1/de not_active Withdrawn
- 2004-04-28 RU RU2005138339/04A patent/RU2383546C2/ru not_active IP Right Cessation
- 2004-04-28 NZ NZ543812A patent/NZ543812A/en not_active IP Right Cessation
- 2004-04-28 EP EP10186283.7A patent/EP2298773B1/de not_active Expired - Lifetime
- 2004-05-07 MY MYPI20041687A patent/MY148252A/en unknown
- 2004-05-07 TW TW093112841A patent/TWI350836B/zh not_active IP Right Cessation
- 2004-05-07 PE PE2004000472A patent/PE20050201A1/es not_active Application Discontinuation
- 2004-05-07 CL CL200400978A patent/CL2004000978A1/es unknown
-
2011
- 2011-11-08 JP JP2011244500A patent/JP5277303B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| TW200508237A (en) | 2005-03-01 |
| JP5277303B2 (ja) | 2013-08-28 |
| TWI350836B (en) | 2011-10-21 |
| NZ543812A (en) | 2010-06-25 |
| RU2383546C2 (ru) | 2010-03-10 |
| RU2005138339A (ru) | 2006-08-10 |
| JP2012036221A (ja) | 2012-02-23 |
| CL2004000978A1 (es) | 2005-03-18 |
| PE20050201A1 (es) | 2005-05-27 |
| EP2298773A1 (de) | 2011-03-23 |
| EP2298773B1 (de) | 2013-06-19 |
| DE102004004142A1 (de) | 2004-11-25 |
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