MY101443A - Analogs of mevalonolactone and derivatives thereof, processes of their production, pharmaceutical compositions containing them and their use as pharmaceuticals - Google Patents
Analogs of mevalonolactone and derivatives thereof, processes of their production, pharmaceutical compositions containing them and their use as pharmaceuticalsInfo
- Publication number
- MY101443A MY101443A MYPI87001949A MYPI19871949A MY101443A MY 101443 A MY101443 A MY 101443A MY PI87001949 A MYPI87001949 A MY PI87001949A MY PI19871949 A MYPI19871949 A MY PI19871949A MY 101443 A MY101443 A MY 101443A
- Authority
- MY
- Malaysia
- Prior art keywords
- mevalonolactone
- pharmaceuticals
- analogs
- hydrogen
- derivatives
- Prior art date
Links
- JYVXNLLUYHCIIH-UHFFFAOYSA-N (+/-)-mevalonolactone Natural products CC1(O)CCOC(=O)C1 JYVXNLLUYHCIIH-UHFFFAOYSA-N 0.000 title 1
- JYVXNLLUYHCIIH-ZCFIWIBFSA-N R-mevalonolactone, (-)- Chemical compound C[C@@]1(O)CCOC(=O)C1 JYVXNLLUYHCIIH-ZCFIWIBFSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940057061 mevalonolactone Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 7
- 229910052739 hydrogen Inorganic materials 0.000 abstract 7
- 239000001257 hydrogen Substances 0.000 abstract 7
- -1 T-BUTOXY Chemical class 0.000 abstract 6
- WZKSXHQDXQKIQJ-UHFFFAOYSA-N F[C](F)F Chemical compound F[C](F)F WZKSXHQDXQKIQJ-UHFFFAOYSA-N 0.000 abstract 3
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical class Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- KHUXNRRPPZOJPT-UHFFFAOYSA-N phenoxy radical Chemical group O=C1C=C[CH]C=C1 KHUXNRRPPZOJPT-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44366882A | 1982-11-22 | 1982-11-22 | |
| EP83810548A EP0114027B1 (en) | 1982-11-22 | 1983-11-22 | Analogs of mevalolactone and derivatives thereof, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY101443A true MY101443A (en) | 1991-11-18 |
Family
ID=23761739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI87001949A MY101443A (en) | 1982-11-22 | 1987-09-25 | Analogs of mevalonolactone and derivatives thereof, processes of their production, pharmaceutical compositions containing them and their use as pharmaceuticals |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS60500015A (oth) |
| KR (1) | KR900009006B1 (oth) |
| ES (1) | ES527428A0 (oth) |
| MY (1) | MY101443A (oth) |
| PH (1) | PH23486A (oth) |
| PT (1) | PT77694B (oth) |
| ZA (1) | ZA838718B (oth) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0532737U (ja) * | 1991-10-11 | 1993-04-30 | 日産自動車株式会社 | ガスタービンのセラミツク構造 |
| CN1536999B (zh) * | 2001-08-03 | 2012-08-08 | 西巴特殊化学品控股有限公司 | 氟伐他汀钠的晶形 |
| KR20050114282A (ko) * | 2003-04-24 | 2005-12-05 | 다이셀 가가꾸 고교 가부시끼가이샤 | 광학 활성의 디히드록시헵텐산 에스테르의 분리 방법 |
| AU2005297984B2 (en) | 2004-10-27 | 2009-11-12 | Daiichi Sankyo Company, Limited | Benzene compound having 2 or more substituents |
| EP2033646A4 (en) | 2006-06-29 | 2009-11-18 | Kowa Co | PREVENTIVE AND / OR THERAPEUTIC AGENT FOR RHEUMATOID ARTHRITIS |
| JP4896220B2 (ja) | 2007-04-27 | 2012-03-14 | 国立大学法人九州大学 | 肺疾患治療薬 |
| WO2011074690A1 (en) | 2009-12-14 | 2011-06-23 | Kyoto University | Pharmaceutical composition for prevention and treatment of amyotrophic lateral sclerosis |
| JP6536871B2 (ja) | 2013-12-02 | 2019-07-03 | 国立大学法人京都大学 | Fgfr3病の予防および治療剤ならびにそのスクリーニング方法 |
| EP3791874B1 (en) | 2018-05-08 | 2025-12-24 | National University Corporation Okayama University | Pemafibrate and pitavastatin for use in reducing hypertension as a major risk factor for cardiovascular diseases |
| US12435311B2 (en) | 2018-12-21 | 2025-10-07 | The University Of Osaka | Lubricin-localized cartilage-like tissue, method for producing same and composition comprising same for treating articular cartilage damage |
| CN113316469A (zh) | 2019-03-13 | 2021-08-27 | 国立大学法人浜松医科大学 | 主动脉瘤的治疗用医药组合物 |
| US20230172996A1 (en) | 2020-02-21 | 2023-06-08 | Yoshikazu NAKAOKA | Composition for alleviating pulmonary hypertension, method for predicting prognosis of pulmonary hypertension, method for assisting in determining severity of pulmonary hypertension, and method for assisting in diagnosing pulmonary hypertension |
-
1983
- 1983-11-18 JP JP58503754A patent/JPS60500015A/ja active Granted
- 1983-11-18 PH PH29858A patent/PH23486A/en unknown
- 1983-11-21 PT PT77694A patent/PT77694B/pt unknown
- 1983-11-21 ES ES527428A patent/ES527428A0/es active Granted
- 1983-11-22 KR KR1019830005533A patent/KR900009006B1/ko not_active Expired
- 1983-11-22 ZA ZA838718A patent/ZA838718B/xx unknown
-
1987
- 1987-09-25 MY MYPI87001949A patent/MY101443A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT77694A (en) | 1983-12-01 |
| JPH0246031B2 (oth) | 1990-10-12 |
| KR840007221A (ko) | 1984-12-06 |
| JPS60500015A (ja) | 1985-01-10 |
| ES8506622A1 (es) | 1985-08-01 |
| ES527428A0 (es) | 1985-08-01 |
| PH23486A (en) | 1989-08-16 |
| ZA838718B (en) | 1985-08-28 |
| PT77694B (en) | 1986-04-17 |
| KR900009006B1 (ko) | 1990-12-17 |
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