MXPA06013191A - Metodos de tratamiento que utilizan proteinas que enlazan albumina como objetivos. - Google Patents
Metodos de tratamiento que utilizan proteinas que enlazan albumina como objetivos.Info
- Publication number
- MXPA06013191A MXPA06013191A MXPA06013191A MXPA06013191A MXPA06013191A MX PA06013191 A MXPA06013191 A MX PA06013191A MX PA06013191 A MXPA06013191 A MX PA06013191A MX PA06013191 A MXPA06013191 A MX PA06013191A MX PA06013191 A MXPA06013191 A MX PA06013191A
- Authority
- MX
- Mexico
- Prior art keywords
- sparc
- antibody
- therapeutic agent
- group
- tumor
- Prior art date
Links
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
- A61K51/1244—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins microparticles or nanoparticles, e.g. polymeric nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Nanotechnology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Dispersion Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Microbiology (AREA)
- Rheumatology (AREA)
- Food Science & Technology (AREA)
- Endocrinology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Reproductive Health (AREA)
- Pain & Pain Management (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57162204P | 2004-05-14 | 2004-05-14 | |
US65426105P | 2005-02-18 | 2005-02-18 | |
PCT/US2005/017174 WO2005117952A2 (en) | 2004-05-14 | 2005-05-16 | Treatment methods utilizing albumin-binding proteins as targets |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA06013191A true MXPA06013191A (es) | 2007-07-24 |
Family
ID=35463351
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA06013191A MXPA06013191A (es) | 2004-05-14 | 2005-05-16 | Metodos de tratamiento que utilizan proteinas que enlazan albumina como objetivos. |
Country Status (8)
Country | Link |
---|---|
EP (3) | EP1755653B1 (zh) |
JP (1) | JP4689666B2 (zh) |
CN (2) | CN1980699B (zh) |
BR (1) | BRPI0511126A (zh) |
CA (1) | CA2566571A1 (zh) |
ES (2) | ES2662848T3 (zh) |
MX (1) | MXPA06013191A (zh) |
WO (1) | WO2005117952A2 (zh) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006524632A (ja) | 2002-12-09 | 2006-11-02 | アメリカン バイオサイエンス、インコーポレイテッド | 組成物及び薬物送達方法 |
US8420603B2 (en) | 2004-05-14 | 2013-04-16 | Abraxis Bioscience, Llc | SPARC and methods of use thereof |
AU2006249235B2 (en) * | 2004-05-14 | 2010-11-11 | Abraxis Bioscience, Llc | Sparc and methods of use thereof |
KR101914254B1 (ko) | 2005-02-18 | 2018-11-02 | 아브락시스 바이오사이언스, 엘엘씨 | 치료제의 조합 및 투여 방식, 및 조합 요법 |
WO2006112930A2 (en) * | 2005-02-18 | 2006-10-26 | Abraxis Bioscience, Inc. | Q3 sparc deletion mutant and uses thereof |
US8735394B2 (en) | 2005-02-18 | 2014-05-27 | Abraxis Bioscience, Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
JP5038407B2 (ja) * | 2006-06-14 | 2012-10-03 | ジョンズ ホプキンズ ユニバーシティー | 疾患のバイオマーカーとしてのアルブミン結合性タンパク質/ペプチド複合体 |
AU2015271950B2 (en) * | 2007-03-07 | 2017-09-28 | Abraxis Bioscience, Llc | Nanoparticle comprising rapamycin and albumin as anticancer agent |
DK2481402T3 (en) * | 2007-03-07 | 2018-08-06 | Abraxis Bioscience Llc | Nanoparticle comprising rapamycin and albumin as anticancer agent |
AU2013204187B2 (en) * | 2007-03-07 | 2015-10-01 | Abraxis Bioscience, Llc | Nanoparticle comprising rapamycin and albumin as anticancer agent |
US20080255035A1 (en) * | 2007-04-13 | 2008-10-16 | Abraxis Bioscience, Inc. | Sparc and methods of use thereof |
ES2435452T3 (es) | 2007-06-01 | 2013-12-19 | Abraxis Bioscience, Llc | Métodos y composiciones para tratar un cáncer recurrente |
CN104174025B (zh) * | 2008-12-05 | 2017-01-11 | 阿布拉西斯生物科学有限责任公司 | Sparc结合肽及其应用 |
US20120009123A1 (en) * | 2008-12-05 | 2012-01-12 | Abraxis Bioscience, Llc | Albumin binding peptide-mediated disease targeting |
MX2012010429A (es) * | 2010-03-11 | 2013-01-29 | Abraxis Bioscience Llc | Dominio angiogenico sparc y metodos de uso. |
DK2552415T3 (en) | 2010-03-29 | 2016-11-28 | Abraxis Bioscience Llc | Methods for treating cancer |
MX2012011155A (es) | 2010-03-29 | 2012-12-05 | Abraxis Bioscience Llc | Metodos para mejorar suministros de farmacos y efectividad de agentes terapeuticos. |
WO2011137441A2 (en) * | 2010-04-30 | 2011-11-03 | Abraxis Bioscience, Llc | Sparc binding aptamers and uses thereof |
KR20130108104A (ko) * | 2010-06-03 | 2013-10-02 | 아브락시스 바이오사이언스, 엘엘씨 | 말초혈 sparc 결합 항체와 이들의 용도 |
CN103140225A (zh) | 2010-06-04 | 2013-06-05 | 阿布拉科斯生物科学有限公司 | 治疗胰腺癌的方法 |
US20170000899A1 (en) * | 2013-11-26 | 2017-01-05 | The Brigham And Women's Hospital, Inc. | Receptor-targeted nanoparticles for enhanced transcytosis mediated drug delivery |
JP6695286B2 (ja) * | 2014-06-13 | 2020-05-20 | メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ | リンパ腫の処置 |
RU2019105550A (ru) * | 2016-08-05 | 2020-09-07 | Мэйо Фаундейшн Фор Медикал Эдьюкейшн Энд Рисерч | Модифицированные комплексы с наночастицами антитело-альбумин для лечения злокачественного новообразования |
CN106755499B (zh) * | 2017-01-24 | 2020-06-30 | 青岛市畜牧兽医研究所 | 一种与奶山羊乳体细胞数性状相关的分子标记及其应用 |
JP2022503696A (ja) * | 2018-10-17 | 2022-01-12 | サンステイト バイオサイエンシーズ, エルエルシー | 治療効果を高めるために単一タンパク質でカプセル化された医薬品 |
JP7466875B2 (ja) * | 2021-02-19 | 2024-04-15 | ソウル大学校産学協力団 | Sparcを発現する癌の治療用組成物 |
CN113842387A (zh) * | 2021-11-19 | 2021-12-28 | 大连理工大学盘锦产业技术研究院 | 10-羟基喜树碱与鹰嘴豆芽素a的药物组合物及其应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6537579B1 (en) | 1993-02-22 | 2003-03-25 | American Bioscience, Inc. | Compositions and methods for administration of pharmacologically active compounds |
US20040018188A9 (en) * | 1999-01-20 | 2004-01-29 | Incyte Genomics, Inc. | Sparc-related proteins |
HU230586B1 (hu) * | 1999-06-25 | 2017-02-28 | Genentech, Inc. | Anti-ErbB antitest/maytansinoid konjugátumok alkalmazása rákos betegségek kezelésére szolgáló gyógyszer előállítására |
CN1240721C (zh) * | 2002-12-03 | 2006-02-08 | 中国医学科学院医药生物技术研究所 | 力达霉素与单克隆抗体及其Fab'片段的偶联物以及在结肠癌等肿瘤靶向治疗中的应用 |
JP2007525167A (ja) * | 2003-04-01 | 2007-09-06 | ジェンザイム・コーポレーション | 乳房内皮細胞発現パターン |
JP4682152B2 (ja) * | 2003-12-31 | 2011-05-11 | ザ・ペン・ステート・リサーチ・ファンデーション | 卵巣がんの化学療法に対する抵抗性を予測および克服するための方法ならびに結腸がんの発生を予測するための方法 |
-
2005
- 2005-05-16 CN CN2005800207487A patent/CN1980699B/zh not_active Expired - Fee Related
- 2005-05-16 ES ES14163409.7T patent/ES2662848T3/es active Active
- 2005-05-16 CN CN2012100082534A patent/CN102614521A/zh active Pending
- 2005-05-16 MX MXPA06013191A patent/MXPA06013191A/es active IP Right Grant
- 2005-05-16 WO PCT/US2005/017174 patent/WO2005117952A2/en active Application Filing
- 2005-05-16 BR BRPI0511126-9A patent/BRPI0511126A/pt active Search and Examination
- 2005-05-16 ES ES05804826.5T patent/ES2529660T3/es active Active
- 2005-05-16 EP EP05804826.5A patent/EP1755653B1/en active Active
- 2005-05-16 JP JP2007513477A patent/JP4689666B2/ja active Active
- 2005-05-16 CA CA002566571A patent/CA2566571A1/en not_active Abandoned
- 2005-05-16 EP EP17209508.5A patent/EP3327031A1/en not_active Withdrawn
- 2005-05-16 EP EP14163409.7A patent/EP2784082B1/en active Active
Also Published As
Publication number | Publication date |
---|---|
BRPI0511126A (pt) | 2007-11-27 |
CN102614521A (zh) | 2012-08-01 |
JP4689666B2 (ja) | 2011-05-25 |
EP3327031A1 (en) | 2018-05-30 |
JP2007537460A (ja) | 2007-12-20 |
EP1755653A2 (en) | 2007-02-28 |
WO2005117952A3 (en) | 2006-04-13 |
EP2784082B1 (en) | 2017-12-27 |
EP1755653A4 (en) | 2008-09-03 |
CA2566571A1 (en) | 2005-12-15 |
EP1755653B1 (en) | 2014-12-31 |
WO2005117952A2 (en) | 2005-12-15 |
ES2662848T3 (es) | 2018-04-10 |
CN1980699A (zh) | 2007-06-13 |
EP2784082A1 (en) | 2014-10-01 |
ES2529660T3 (es) | 2015-02-24 |
CN1980699B (zh) | 2012-03-21 |
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