MXPA06003318A - Composiciones a base de virus de seneca valley y metodos para tratar la enfermedad. - Google Patents

Composiciones a base de virus de seneca valley y metodos para tratar la enfermedad.

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Publication number
MXPA06003318A
MXPA06003318A MXPA06003318A MXPA06003318A MXPA06003318A MX PA06003318 A MXPA06003318 A MX PA06003318A MX PA06003318 A MXPA06003318 A MX PA06003318A MX PA06003318 A MXPA06003318 A MX PA06003318A MX PA06003318 A MXPA06003318 A MX PA06003318A
Authority
MX
Mexico
Prior art keywords
virus
cell
sequence
tumor
mutant
Prior art date
Application number
MXPA06003318A
Other languages
English (en)
Spanish (es)
Inventor
Cheng Cheng
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MXPA06003318A publication Critical patent/MXPA06003318A/es

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • A61K35/768Oncolytic viruses not provided for in groups A61K35/761 - A61K35/766
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08RNA viruses
    • C07K14/085Picornaviridae, e.g. coxsackie virus, echovirus, enterovirus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32061Methods of inactivation or attenuation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
MXPA06003318A 2003-09-26 2004-09-23 Composiciones a base de virus de seneca valley y metodos para tratar la enfermedad. MXPA06003318A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50618203P 2003-09-26 2003-09-26
PCT/US2004/031504 WO2005030139A2 (en) 2003-09-26 2004-09-23 Seneca valley virus based compositions and methods for treating disease

Publications (1)

Publication Number Publication Date
MXPA06003318A true MXPA06003318A (es) 2006-06-08

Family

ID=34393123

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA06003318A MXPA06003318A (es) 2003-09-26 2004-09-23 Composiciones a base de virus de seneca valley y metodos para tratar la enfermedad.

Country Status (12)

Country Link
EP (1) EP1668025B1 (enExample)
JP (1) JP2007506434A (enExample)
KR (1) KR20060103890A (enExample)
CN (1) CN1875028B (enExample)
AU (1) AU2004275832A1 (enExample)
BR (1) BRPI0414810A (enExample)
CA (1) CA2540177A1 (enExample)
DK (1) DK1668025T3 (enExample)
IL (1) IL174430A0 (enExample)
MX (1) MXPA06003318A (enExample)
SG (1) SG149069A1 (enExample)
WO (1) WO2005030139A2 (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPQ425699A0 (en) 1999-11-25 1999-12-23 University Of Newcastle Research Associates Limited, The A method of treating a malignancy in a subject and a pharmaceutical composition for use in same
AU2002953436A0 (en) 2002-12-18 2003-01-09 The University Of Newcastle Research Associates Limited A method of treating a malignancy in a subject via direct picornaviral-mediated oncolysis
US7638318B2 (en) 2003-09-26 2009-12-29 Norvartis Ag Seneca Valley virus based compositions and methods for treating disease
WO2007047256A2 (en) * 2005-10-13 2007-04-26 Neotropix, Inc. Svv-based animal vaccines and uses thereof
ES2923782T3 (es) 2015-12-02 2022-09-30 Memorial Sloan Kettering Cancer Center Oncoterapia dirigida al receptor celular del virus del Valle de Séneca (SVV)
CN105925728B (zh) * 2016-06-01 2019-09-20 华南农业大学 一种塞内加谷病毒实时荧光定量pcr检测引物及试剂盒
US10323069B2 (en) * 2016-08-23 2019-06-18 Regents Of The University Of Minnesota Senecavirus A antigens and methods of use
CA3069821A1 (en) * 2017-07-14 2019-01-17 Oncorus, Inc. Encapsulated polynucleotides and methods of use
CN107253978B (zh) * 2017-08-13 2020-11-20 中牧实业股份有限公司 塞尼卡谷病毒结构蛋白抗体酶联免疫检测试剂盒
CN107513524B (zh) * 2017-09-30 2021-02-09 中牧实业股份有限公司 一株猪塞内加谷病毒毒株及其应用
CN108467904B (zh) * 2018-05-24 2021-11-19 华南农业大学 检测塞尼卡谷病毒的rt-lamp引物组、试剂盒及应用
CN109182278B (zh) * 2018-10-12 2021-08-06 河南省动物疫病预防控制中心 塞尼卡谷病毒毒株及其应用
KR20210093285A (ko) * 2018-11-13 2021-07-27 온코루스, 인크. 캡슐화된 폴리뉴클레오티드 및 사용 방법
CN109234464A (zh) * 2018-11-23 2019-01-18 山东新希望六和集团有限公司 用于检测塞尼卡谷病毒的引物及探针、荧光定量pcr试剂盒及方法和应用
CN111733144A (zh) * 2019-03-25 2020-10-02 金宇保灵生物药品有限公司 一种塞内卡病毒的纯化方法及病毒液的浓缩纯化方法
CN110229218B (zh) * 2019-06-24 2020-12-01 中国动物疫病预防控制中心(农业农村部屠宰技术中心) 检测塞内卡病毒抗体的试剂及其所用多肽
US12502414B2 (en) 2019-07-19 2025-12-23 Seneca Therapeutics, Inc. Second generation Seneca Valley virus oncolytic therapy: compositions and methods thereof
CN110923211A (zh) * 2019-12-25 2020-03-27 哈药集团生物疫苗有限公司 塞内卡病毒分离株、塞内卡病毒病灭活疫苗及其制备方法
CN111286491A (zh) * 2020-02-03 2020-06-16 河南省动物疫病预防控制中心 猪塞内卡病毒核酸标准物及其应用
CN111849925B (zh) * 2020-07-06 2022-06-03 马忠仁 一种抗结肠癌疫苗及其制法
CN111798712B (zh) * 2020-07-15 2021-10-29 周晓庆 噬菌体侵染细菌3d智能模拟方法
CN111944764A (zh) * 2020-08-31 2020-11-17 信阳农林学院 一种表达猪塞内加谷病毒蛋白的细胞系、构建方法和应用
CN112390861A (zh) * 2020-09-30 2021-02-23 信阳农林学院 表达猪塞内加谷病毒vp1蛋白的细胞系、构建方法和应用
CN117281824B (zh) * 2023-08-11 2025-10-21 华南农业大学 Trim基因的过表达剂在制备抑制猪塞内卡病毒复制的产品中的应用
CN117487006B (zh) * 2023-12-29 2024-04-12 中国农业科学院哈尔滨兽医研究所(中国动物卫生与流行病学中心哈尔滨分中心) 一种抗a型塞内卡病毒的单克隆抗体以及抗原表位及应用

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Publication number Priority date Publication date Assignee Title
US6110461A (en) * 1997-08-13 2000-08-29 Oncolytics Biotech Inc. Reovirus for the treatment of neoplasia

Also Published As

Publication number Publication date
EP1668025A2 (en) 2006-06-14
CN1875028B (zh) 2012-07-04
IL174430A0 (en) 2006-08-01
WO2005030139A2 (en) 2005-04-07
WO2005030139A3 (en) 2005-10-20
SG149069A1 (en) 2009-01-29
KR20060103890A (ko) 2006-10-04
EP1668025A4 (en) 2007-05-16
HK1094583A1 (en) 2007-04-04
DK1668025T3 (da) 2014-08-25
CN1875028A (zh) 2006-12-06
JP2007506434A (ja) 2007-03-22
AU2004275832A1 (en) 2005-04-07
EP1668025B1 (en) 2014-06-25
CA2540177A1 (en) 2005-04-07
BRPI0414810A (pt) 2006-11-14

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