MXPA06003125A - Composiciones farmaceuticas de modafinilo de liberacion modificada. - Google Patents
Composiciones farmaceuticas de modafinilo de liberacion modificada.Info
- Publication number
- MXPA06003125A MXPA06003125A MXPA06003125A MXPA06003125A MXPA06003125A MX PA06003125 A MXPA06003125 A MX PA06003125A MX PA06003125 A MXPA06003125 A MX PA06003125A MX PA06003125 A MXPA06003125 A MX PA06003125A MX PA06003125 A MXPA06003125 A MX PA06003125A
- Authority
- MX
- Mexico
- Prior art keywords
- modafinil
- pharmaceutical composition
- composition according
- modafinil compound
- dosage form
- Prior art date
Links
- 229960001165 modafinil Drugs 0.000 title claims abstract description 273
- YFGHCGITMMYXAQ-UHFFFAOYSA-N 2-[(diphenylmethyl)sulfinyl]acetamide Chemical compound C=1C=CC=CC=1C(S(=O)CC(=O)N)C1=CC=CC=C1 YFGHCGITMMYXAQ-UHFFFAOYSA-N 0.000 title claims abstract description 249
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 59
- 239000000203 mixture Substances 0.000 claims description 132
- 239000002552 dosage form Substances 0.000 claims description 111
- 238000009472 formulation Methods 0.000 claims description 79
- 239000003814 drug Substances 0.000 claims description 65
- 229940079593 drug Drugs 0.000 claims description 63
- -1 modafinil compound Chemical class 0.000 claims description 53
- 239000012730 sustained-release form Substances 0.000 claims description 53
- 238000013268 sustained release Methods 0.000 claims description 52
- 239000012729 immediate-release (IR) formulation Substances 0.000 claims description 45
- 239000002245 particle Substances 0.000 claims description 44
- 239000002775 capsule Substances 0.000 claims description 38
- 229920000642 polymer Polymers 0.000 claims description 38
- 238000000034 method Methods 0.000 claims description 29
- 230000000541 pulsatile effect Effects 0.000 claims description 29
- 230000003111 delayed effect Effects 0.000 claims description 28
- 238000013265 extended release Methods 0.000 claims description 27
- 239000012528 membrane Substances 0.000 claims description 27
- 206010041349 Somnolence Diseases 0.000 claims description 25
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- 229920003176 water-insoluble polymer Polymers 0.000 claims description 13
- 239000011248 coating agent Substances 0.000 claims description 12
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims description 12
- 239000011230 binding agent Substances 0.000 claims description 11
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- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 6
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- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 6
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 6
- URAYPUMNDPQOKB-UHFFFAOYSA-N triacetin Chemical group CC(=O)OCC(OC(C)=O)COC(C)=O URAYPUMNDPQOKB-UHFFFAOYSA-N 0.000 claims description 6
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- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims description 5
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- ZFOZVQLOBQUTQQ-UHFFFAOYSA-N Tributyl citrate Chemical compound CCCCOC(=O)CC(O)(C(=O)OCCCC)CC(=O)OCCCC ZFOZVQLOBQUTQQ-UHFFFAOYSA-N 0.000 claims description 4
- FLKPEMZONWLCSK-UHFFFAOYSA-N diethyl phthalate Chemical compound CCOC(=O)C1=CC=CC=C1C(=O)OCC FLKPEMZONWLCSK-UHFFFAOYSA-N 0.000 claims description 4
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- 229960002622 triacetin Drugs 0.000 claims description 3
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- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims description 2
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- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims description 2
- DOOTYTYQINUNNV-UHFFFAOYSA-N Triethyl citrate Chemical compound CCOC(=O)CC(O)(C(=O)OCC)CC(=O)OCC DOOTYTYQINUNNV-UHFFFAOYSA-N 0.000 claims description 2
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 2
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims description 2
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 claims description 2
- 239000004359 castor oil Substances 0.000 claims description 2
- 235000019438 castor oil Nutrition 0.000 claims description 2
- 235000015165 citric acid Nutrition 0.000 claims description 2
- 238000013270 controlled release Methods 0.000 claims description 2
- 229940099371 diacetylated monoglycerides Drugs 0.000 claims description 2
- 239000001530 fumaric acid Substances 0.000 claims description 2
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims description 2
- 238000000227 grinding Methods 0.000 claims description 2
- 229960001021 lactose monohydrate Drugs 0.000 claims description 2
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 claims description 2
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- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 claims description 2
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- IWVKTOUOPHGZRX-UHFFFAOYSA-N methyl 2-methylprop-2-enoate;2-methylprop-2-enoic acid Chemical compound CC(=C)C(O)=O.COC(=O)C(C)=C IWVKTOUOPHGZRX-UHFFFAOYSA-N 0.000 claims 1
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- OHHDIOKRWWOXMT-UHFFFAOYSA-N trazodone hydrochloride Chemical compound [H+].[Cl-].ClC1=CC=CC(N2CCN(CCCN3C(N4C=CC=CC4=N3)=O)CC2)=C1 OHHDIOKRWWOXMT-UHFFFAOYSA-N 0.000 description 1
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 description 1
- 239000003029 tricyclic antidepressant agent Substances 0.000 description 1
- BXDAOUXDMHXPDI-UHFFFAOYSA-N trifluoperazine hydrochloride Chemical compound [H+].[H+].[Cl-].[Cl-].C1CN(C)CCN1CCCN1C2=CC(C(F)(F)F)=CC=C2SC2=CC=CC=C21 BXDAOUXDMHXPDI-UHFFFAOYSA-N 0.000 description 1
- 229960002431 trimipramine Drugs 0.000 description 1
- ZSCDBOWYZJWBIY-UHFFFAOYSA-N trimipramine Chemical compound C1CC2=CC=CC=C2N(CC(CN(C)C)C)C2=CC=CC=C21 ZSCDBOWYZJWBIY-UHFFFAOYSA-N 0.000 description 1
- 229960002835 trimipramine maleate Drugs 0.000 description 1
- YDGHCKHAXOUQOS-BTJKTKAUSA-N trimipramine maleate Chemical compound [O-]C(=O)\C=C/C([O-])=O.C1CC2=CC=CC=C2[NH+](CC(C[NH+](C)C)C)C2=CC=CC=C21 YDGHCKHAXOUQOS-BTJKTKAUSA-N 0.000 description 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
- 238000000870 ultraviolet spectroscopy Methods 0.000 description 1
- 229960005014 viloxazine hydrochloride Drugs 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
- 230000002618 waking effect Effects 0.000 description 1
- 239000009637 wintergreen oil Substances 0.000 description 1
- CJGOZEVWXQGMCS-UHFFFAOYSA-N zometapine Chemical compound CN1NC(C)=C2C1=NCCN=C2C1=CC=CC(Cl)=C1 CJGOZEVWXQGMCS-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50402803P | 2003-09-18 | 2003-09-18 | |
| US10/944,528 US8153159B2 (en) | 2003-09-18 | 2004-09-17 | Modafinil modified release pharmaceutical compositions |
| PCT/US2004/030815 WO2005027890A1 (en) | 2003-09-18 | 2004-09-20 | Modafinil modified release pharmaceutical compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA06003125A true MXPA06003125A (es) | 2006-06-20 |
Family
ID=34381093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA06003125A MXPA06003125A (es) | 2003-09-18 | 2004-09-20 | Composiciones farmaceuticas de modafinilo de liberacion modificada. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US8153159B2 (enExample) |
| EP (1) | EP1670447B1 (enExample) |
| JP (1) | JP5138932B2 (enExample) |
| KR (1) | KR20060117910A (enExample) |
| AR (1) | AR046410A1 (enExample) |
| AT (1) | ATE448780T1 (enExample) |
| AU (1) | AU2004274017B2 (enExample) |
| BR (1) | BRPI0414299A (enExample) |
| CA (1) | CA2536666C (enExample) |
| DE (1) | DE602004024220D1 (enExample) |
| EA (1) | EA011400B1 (enExample) |
| ES (1) | ES2336215T3 (enExample) |
| IL (1) | IL173738A (enExample) |
| IS (1) | IS2787B (enExample) |
| MX (1) | MXPA06003125A (enExample) |
| MY (1) | MY144755A (enExample) |
| NO (1) | NO20060964L (enExample) |
| NZ (1) | NZ545573A (enExample) |
| TW (1) | TWI344840B (enExample) |
| WO (1) | WO2005027890A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA01004381A (es) * | 1998-11-02 | 2005-09-08 | Elan Corp Plc | Composicion de multiparticulado de liberacion modificada. |
| EP1755388B1 (en) | 2004-05-28 | 2010-10-06 | Transform Pharmaceuticals, Inc. | Mixed co-crystals and pharmaceutical compositions comprising the same |
| WO2006063078A2 (en) * | 2004-12-08 | 2006-06-15 | Elan Corporation, Plc | Topiramate pharmaceuticals composition |
| WO2007037790A2 (en) * | 2005-06-08 | 2007-04-05 | Elan Corporation, Plc | Modified release famciclovir compositions |
| CA2642275A1 (en) | 2006-02-13 | 2007-08-23 | Vanda Pharmaceuticals, Inc. | Stable dosage formulations of imidazolylalkyl-pyridines |
| AU2007272501A1 (en) * | 2006-07-12 | 2008-01-17 | Elan Pharma International Limited | Nanoparticulate formulations of modafinil |
| DE102006035549A1 (de) | 2006-07-27 | 2008-01-31 | Evonik Röhm Gmbh | Arzneiform mit mindestens zweischichtiger Trennschicht |
| US20090082461A1 (en) * | 2007-09-25 | 2009-03-26 | Protia, Llc | Deuterium-enriched modafinil |
| JP5250285B2 (ja) * | 2008-03-26 | 2013-07-31 | 富士フイルム株式会社 | 経口物用被覆材、可食性容器およびそれらを用いた経口物 |
| WO2010012407A1 (en) * | 2008-07-29 | 2010-02-04 | Ashland Licensing And Intellectual Property Llc. | Modified additives for suppressing dust formation |
| MX2013000001A (es) * | 2010-07-06 | 2013-05-01 | Navipharm Co Ltd | Composición farmaceutica de liberacion prolongada y acción retardada que comprende dapoxetina para administaracion oral. |
| US8999393B1 (en) * | 2013-01-09 | 2015-04-07 | Edgemont Pharmaceuticals Llc | Sustained release formulations of lorazepam |
| MX2016014320A (es) | 2014-05-01 | 2017-05-23 | Sun Pharmaceutical Ind Ltd | Composiciones de suspension de liberacion prolongada. |
| ES3008933T3 (en) | 2015-09-29 | 2025-03-25 | Merz Pharmaceuticals Llc | Sustained release compositions of 4-aminopyridine |
| TWI838340B (zh) * | 2017-07-10 | 2024-04-11 | 日商武田藥品工業股份有限公司 | 含有沃諾拉贊的製劑 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5534263A (en) * | 1995-02-24 | 1996-07-09 | Alza Corporation | Active agent dosage form comprising a matrix and at least two insoluble bands |
| US6346548B1 (en) * | 1999-08-16 | 2002-02-12 | Cephalon, Inc. | Compositions including modafinil for treatment of attention deficit hyperactivity disorder and multiple sclerosis fatigue |
| US6627223B2 (en) * | 2000-02-11 | 2003-09-30 | Eurand Pharmaceuticals Ltd. | Timed pulsatile drug delivery systems |
| US6458384B2 (en) * | 2000-02-23 | 2002-10-01 | Impetus Ag | Pharmaceutical with predetermined activity profile |
| US6492396B2 (en) | 2000-05-16 | 2002-12-10 | Cephalon, Inc. | Substituted thioacetamides |
| US6489363B2 (en) * | 2000-10-11 | 2002-12-03 | Cephalon, Inc. | Pharmaceutical solutions of modafinil compounds |
| US6344215B1 (en) * | 2000-10-27 | 2002-02-05 | Eurand America, Inc. | Methylphenidate modified release formulations |
| US7141555B2 (en) | 2000-12-19 | 2006-11-28 | Cephalon, Inc. | Modafinil compound and cyclodextrin mixtures |
| US7297346B2 (en) | 2001-05-25 | 2007-11-20 | Cephalon Inc. | Pharmaceutical formulations of modafinil |
| GB0117618D0 (en) | 2001-07-19 | 2001-09-12 | Phoqus Ltd | Pharmaceutical dosage form |
| US7229644B2 (en) * | 2002-05-23 | 2007-06-12 | Cephalon, Inc. | Pharmaceutical formulations of modafinil |
| US20040116532A1 (en) | 2002-09-13 | 2004-06-17 | Craig Heacock | Pharmaceutical formulations of modafinil |
-
2004
- 2004-09-17 US US10/944,528 patent/US8153159B2/en not_active Expired - Fee Related
- 2004-09-17 AR ARP040103336A patent/AR046410A1/es unknown
- 2004-09-20 CA CA2536666A patent/CA2536666C/en not_active Expired - Fee Related
- 2004-09-20 MX MXPA06003125A patent/MXPA06003125A/es active IP Right Grant
- 2004-09-20 AU AU2004274017A patent/AU2004274017B2/en not_active Ceased
- 2004-09-20 NZ NZ545573A patent/NZ545573A/en not_active IP Right Cessation
- 2004-09-20 KR KR1020067005361A patent/KR20060117910A/ko not_active Ceased
- 2004-09-20 TW TW093128394A patent/TWI344840B/zh not_active IP Right Cessation
- 2004-09-20 EA EA200600590A patent/EA011400B1/ru not_active IP Right Cessation
- 2004-09-20 JP JP2006527123A patent/JP5138932B2/ja not_active Expired - Fee Related
- 2004-09-20 WO PCT/US2004/030815 patent/WO2005027890A1/en not_active Ceased
- 2004-09-20 DE DE602004024220T patent/DE602004024220D1/de not_active Expired - Lifetime
- 2004-09-20 MY MYPI20043844A patent/MY144755A/en unknown
- 2004-09-20 BR BRPI0414299-3A patent/BRPI0414299A/pt not_active IP Right Cessation
- 2004-09-20 EP EP04788862A patent/EP1670447B1/en not_active Expired - Lifetime
- 2004-09-20 AT AT04788862T patent/ATE448780T1/de not_active IP Right Cessation
- 2004-09-20 ES ES04788862T patent/ES2336215T3/es not_active Expired - Lifetime
-
2006
- 2006-02-14 IL IL173738A patent/IL173738A/en not_active IP Right Cessation
- 2006-02-23 IS IS8327A patent/IS2787B/is unknown
- 2006-02-28 NO NO20060964A patent/NO20060964L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE448780T1 (de) | 2009-12-15 |
| WO2005027890A1 (en) | 2005-03-31 |
| IL173738A0 (en) | 2006-07-05 |
| ES2336215T3 (es) | 2010-04-09 |
| IS2787B (is) | 2012-06-15 |
| CA2536666A1 (en) | 2005-03-31 |
| TWI344840B (en) | 2011-07-11 |
| EA011400B1 (ru) | 2009-02-27 |
| AU2004274017A1 (en) | 2005-03-31 |
| JP2007518696A (ja) | 2007-07-12 |
| IS8327A (is) | 2006-02-23 |
| EA200600590A1 (ru) | 2006-08-25 |
| AR046410A1 (es) | 2005-12-07 |
| CA2536666C (en) | 2012-06-19 |
| BRPI0414299A (pt) | 2006-11-14 |
| KR20060117910A (ko) | 2006-11-17 |
| NO20060964L (no) | 2006-04-18 |
| EP1670447B1 (en) | 2009-11-18 |
| HK1089697A1 (en) | 2006-12-08 |
| US8153159B2 (en) | 2012-04-10 |
| NZ545573A (en) | 2010-02-26 |
| US20050095294A1 (en) | 2005-05-05 |
| MY144755A (en) | 2011-10-31 |
| AU2004274017B2 (en) | 2010-07-08 |
| TW200520748A (en) | 2005-07-01 |
| EP1670447A1 (en) | 2006-06-21 |
| IL173738A (en) | 2012-07-31 |
| DE602004024220D1 (de) | 2009-12-31 |
| JP5138932B2 (ja) | 2013-02-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |