MXPA05012758A - Derivados de captopril. - Google Patents

Derivados de captopril.

Info

Publication number
MXPA05012758A
MXPA05012758A MXPA05012758A MXPA05012758A MXPA05012758A MX PA05012758 A MXPA05012758 A MX PA05012758A MX PA05012758 A MXPA05012758 A MX PA05012758A MX PA05012758 A MXPA05012758 A MX PA05012758A MX PA05012758 A MXPA05012758 A MX PA05012758A
Authority
MX
Mexico
Prior art keywords
captopril
derivatives
captopril derivatives
nitroderivatives
prophylaxis
Prior art date
Application number
MXPA05012758A
Other languages
English (en)
Inventor
Nicoletta Almirante
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox Sa filed Critical Nicox Sa
Publication of MXPA05012758A publication Critical patent/MXPA05012758A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Pyrrole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se describen derivados nitro de captopril que tienen una mejor actividad farmacologica y una mayor tolerabilidad; se pueden usar para el tratamiento o profilaxis de enfermedades cardiovasculares, inflamatorias y renales.
MXPA05012758A 2003-05-28 2004-05-24 Derivados de captopril. MXPA05012758A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03101553 2003-05-28
PCT/EP2004/050899 WO2004106300A1 (en) 2003-05-28 2004-05-24 Captopril derivatives

Publications (1)

Publication Number Publication Date
MXPA05012758A true MXPA05012758A (es) 2006-02-13

Family

ID=33483995

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05012758A MXPA05012758A (es) 2003-05-28 2004-05-24 Derivados de captopril.

Country Status (15)

Country Link
US (1) US7169805B2 (es)
EP (1) EP1626955A1 (es)
JP (1) JP4649410B2 (es)
KR (1) KR20060013413A (es)
CN (1) CN1795173A (es)
AR (1) AR044568A1 (es)
AU (1) AU2004242799A1 (es)
BR (1) BRPI0410020A (es)
CA (1) CA2527382A1 (es)
MX (1) MXPA05012758A (es)
NO (1) NO20056199L (es)
PL (1) PL379168A1 (es)
RU (1) RU2005135695A (es)
WO (1) WO2004106300A1 (es)
ZA (1) ZA200509459B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200616604A (en) 2004-08-26 2006-06-01 Nicholas Piramal India Ltd Nitric oxide releasing prodrugs containing bio-cleavable linker
RU2007110846A (ru) 2004-08-26 2008-10-10 Николас Пайрамал Индия Лимитед (In) Пролекарства, включающие новые биодеградируемые линкеры
WO2011160974A2 (en) 2010-06-21 2011-12-29 Nicox S.A. Statin derivatives

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105776A (en) * 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
JPS559058A (en) * 1978-07-06 1980-01-22 Dainippon Pharmaceut Co Ltd 1-(3-mercapto-2-methylpropanoyl)prolyl amino acid derivative
US4399144A (en) * 1980-04-30 1983-08-16 John Wyeth And Brother Limited Pyridinium salts
WO1990002118A1 (en) 1988-08-26 1990-03-08 Sepracor, Inc. Derivatives and precursors of captopril and its analogues
US5380758A (en) * 1991-03-29 1995-01-10 Brigham And Women's Hospital S-nitrosothiols as smooth muscle relaxants and therapeutic uses thereof
AU1670995A (en) * 1994-01-28 1995-08-15 Cal International Limited A pharmaceutical product comprising a salicylate of an esterifiable ace-inhibitor
UA58494C2 (uk) * 1995-06-07 2003-08-15 Зенека Лімітед Похідні n-гетероарилпіридинсульфонаміду, фармацевтична композиція, спосіб одержання та спосіб протидії впливам ендотеліну
GB9517998D0 (en) * 1995-09-04 1995-11-08 Bioglan Lab Ltd Compositions and device for their administration
IT1276071B1 (it) 1995-10-31 1997-10-24 Nicox Ltd Compositi ad attivita' anti-infiammatoria
US6294517B1 (en) * 1996-02-02 2001-09-25 Nitromed, Inc. Compositions and kits comprising alpha-adrenergic receptor antagonists and nitric oxide donors and methods of use
JPH09291075A (ja) * 1996-03-01 1997-11-11 Sankyo Co Ltd チアゾリジン類
US6331543B1 (en) * 1996-11-01 2001-12-18 Nitromed, Inc. Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use
IT1295694B1 (it) * 1996-11-14 1999-05-27 Nicox Sa Nitrossi derivati per la preparazione di medicamenti ad attivita antitrombinica
IT1292426B1 (it) * 1997-06-27 1999-02-08 Nicox Sa Sali nitrati di ace-inibitori
JPH1171279A (ja) 1997-08-27 1999-03-16 Sankyo Co Ltd チアゾリジン類を有効成分として含有する狭心症予防剤又は治療剤
US6223744B1 (en) * 1999-03-16 2001-05-01 Multi-Vet Ltd. Wearable aerosol delivery apparatus
IT1311924B1 (it) 1999-04-13 2002-03-20 Nicox Sa Composti farmaceutici.
IT1311923B1 (it) 1999-04-13 2002-03-20 Nicox Sa Composti farmaceutici.
IT1314184B1 (it) 1999-08-12 2002-12-06 Nicox Sa Composizioni farmaceutiche per la terapia di condizioni di stressossidativo
CA2383252A1 (en) * 1999-08-24 2001-03-01 Medicure International Inc. Treatment of cardiovascular related pathologies
EE05670B1 (et) * 1999-08-30 2013-08-15 Aventis Pharma Deutschland Gmbh Ramipriil kardiovaskulaarsete haigusjuhtude „rahoidmiseks
WO2001054677A2 (en) * 2000-01-26 2001-08-02 Warner-Lambert Company Ace inhibitor-vasopressin antagonist combinations
AU5939901A (en) * 2000-10-27 2002-05-06 Nitromed Inc Methods of treating vascular diseases characterized by nitric oxide insufficiency
ITMI20011240A1 (it) * 2001-06-13 2002-12-13 Nicox Sa Farmaci per le vasculopatie

Also Published As

Publication number Publication date
CA2527382A1 (en) 2004-12-09
AR044568A1 (es) 2005-09-21
NO20056199L (no) 2006-02-13
CN1795173A (zh) 2006-06-28
RU2005135695A (ru) 2006-05-27
AU2004242799A1 (en) 2004-12-09
PL379168A1 (pl) 2006-07-24
US7169805B2 (en) 2007-01-30
BRPI0410020A (pt) 2006-04-25
US20040259808A1 (en) 2004-12-23
JP4649410B2 (ja) 2011-03-09
JP2006528230A (ja) 2006-12-14
EP1626955A1 (en) 2006-02-22
ZA200509459B (en) 2006-11-29
KR20060013413A (ko) 2006-02-09
WO2004106300A1 (en) 2004-12-09

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