MXPA05008785A - Esteres de polietilen glicol activados. - Google Patents

Esteres de polietilen glicol activados.

Info

Publication number
MXPA05008785A
MXPA05008785A MXPA05008785A MXPA05008785A MXPA05008785A MX PA05008785 A MXPA05008785 A MX PA05008785A MX PA05008785 A MXPA05008785 A MX PA05008785A MX PA05008785 A MXPA05008785 A MX PA05008785A MX PA05008785 A MXPA05008785 A MX PA05008785A
Authority
MX
Mexico
Prior art keywords
esters
oxalate
polyethylene glycol
carbonate
activated
Prior art date
Application number
MXPA05008785A
Other languages
English (en)
Spanish (es)
Inventor
Foe Siong Tjoeng
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of MXPA05008785A publication Critical patent/MXPA05008785A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A61P5/08Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Polyethers (AREA)
  • Polyesters Or Polycarbonates (AREA)
MXPA05008785A 2003-02-19 2004-02-13 Esteres de polietilen glicol activados. MXPA05008785A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44835403P 2003-02-19 2003-02-19
PCT/IB2004/000424 WO2004074345A2 (en) 2003-02-19 2004-02-13 Carbonate esters of polyethylene glycol activated by means of oxalate esters

Publications (1)

Publication Number Publication Date
MXPA05008785A true MXPA05008785A (es) 2005-10-18

Family

ID=32908577

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05008785A MXPA05008785A (es) 2003-02-19 2004-02-13 Esteres de polietilen glicol activados.

Country Status (9)

Country Link
US (1) US7094872B2 (https=)
EP (1) EP1597299A2 (https=)
JP (1) JP2006517995A (https=)
AR (1) AR043216A1 (https=)
BR (1) BRPI0407511A (https=)
CA (1) CA2515612A1 (https=)
MX (1) MXPA05008785A (https=)
TW (1) TW200426155A (https=)
WO (1) WO2004074345A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1259563T4 (en) 1999-12-22 2016-11-21 Nektar Therapeutics PROCEDURE FOR PREPARING 1-BENZOTRIAZOLYL CARBONATE ESTERS OF WATER SOLUBLE POLYMERS
ATE371680T1 (de) 2002-01-16 2007-09-15 Biocompatibles Uk Ltd Polymerkonjugate
GB0301014D0 (en) * 2003-01-16 2003-02-19 Biocompatibles Ltd Conjugation reactions
ITPD20040159A1 (it) * 2004-06-21 2004-09-21 Univ Degli Studi Trieste Derivati bifunzionali del polietilenglicole loro preparazione e uso.
US8133707B2 (en) * 2006-01-17 2012-03-13 Enzon Pharmaceuticals, Inc. Methods of preparing activated polymers having alpha nitrogen groups
JP2007209543A (ja) * 2006-02-09 2007-08-23 Hidetoshi Tsuchida 表面修飾アルブミンからなる固相膜および酸素吸着膜
JP2009533347A (ja) 2006-04-07 2009-09-17 ネクター セラピューティックス エイエル,コーポレイション 抗TNFα抗体の複合体
EP4089133A1 (en) * 2021-05-14 2022-11-16 Johannes Gutenberg-Universität Mainz Poly(ethylene glycol) having c1 to c3-alkyloxymethyl side chains, bioconjugates thereof, process for its preparation and its use.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4342832A (en) * 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
US5618697A (en) * 1982-12-10 1997-04-08 Novo Nordisk A/S Process for preparing a desired protein
US5122614A (en) * 1989-04-19 1992-06-16 Enzon, Inc. Active carbonates of polyalkylene oxides for modification of polypeptides
JPH07500315A (ja) * 1991-05-10 1995-01-12 セルトリックス ファーマシューティカルズ,インコーポレイテッド 骨成長因子の標的送達
US5281698A (en) * 1991-07-23 1994-01-25 Cetus Oncology Corporation Preparation of an activated polymer ester for protein conjugation
US5382657A (en) * 1992-08-26 1995-01-17 Hoffmann-La Roche Inc. Peg-interferon conjugates
US5650234A (en) * 1994-09-09 1997-07-22 Surface Engineering Technologies, Division Of Innerdyne, Inc. Electrophilic polyethylene oxides for the modification of polysaccharides, polypeptides (proteins) and surfaces
US5932462A (en) * 1995-01-10 1999-08-03 Shearwater Polymers, Inc. Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
US6180095B1 (en) * 1997-12-17 2001-01-30 Enzon, Inc. Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
GB0013810D0 (en) * 2000-06-06 2000-07-26 Celltech Chiroscience Ltd Biological products

Also Published As

Publication number Publication date
US7094872B2 (en) 2006-08-22
AR043216A1 (es) 2005-07-20
TW200426155A (en) 2004-12-01
CA2515612A1 (en) 2004-09-02
WO2004074345A3 (en) 2005-01-20
JP2006517995A (ja) 2006-08-03
US20040162388A1 (en) 2004-08-19
EP1597299A2 (en) 2005-11-23
BRPI0407511A (pt) 2006-02-14
WO2004074345A2 (en) 2004-09-02

Similar Documents

Publication Publication Date Title
EP2298331A3 (en) Use of transthyretin peptide/protein fusions to increase the serum half-life of pharmacologically active peptides/proteins
CY1119243T1 (el) Φαρμακοτεχνικες μορφες ανταγωνιστη του vegf
AU2003228962A1 (en) Ferritin fusion proteins for use in vaccines and other applications
CY1114244T1 (el) Σκευασματα ανταγωνιστη vegf καταλληλα για ενδοϋαλωδη χορηγηση
IL195338A (en) An antibody comprising an FC variant containing amino acid replaces d or e at position 239, a medicament containing it and its use
NZ591261A (en) Improvements in the absorption of therapeutic agents across mucosal membranes or the skin
EA200500644A1 (ru) Высокоэффективные способные к слиянию везикулы, способ их получения и фармацевтическая композиция, их содержащая
AU4981101A (en) Subtilisin variants
BRPI0113477B8 (pt) proteína de fusão para distribuição de um peptídeo, proteína, glicoproteína ou oligonucleotídeo em uma célula
WO2004111081A3 (en) Antigenic peptides of sars coronavirus and uses thereof
WO2002055098A3 (en) Latency associated peptide for providing latency to pharmaceutically active proteins
WO2003028757A1 (en) Novel method of inducing antigen-specific t cells
WO2004074486A3 (en) Fusion proteins of interferon alpha muteins with improved properties
DE60236796D1 (de) Verzweigte polyalkylenglykole
WO2006023665A3 (en) Il-1 antagonist formulations
MXPA05008785A (es) Esteres de polietilen glicol activados.
BR0009472A (pt) Antagonistas de lhrh com propriedades desolubilidade aperfeiçoadas
WO2006060021A3 (en) Bifunctional fusion proteins containing the flt3 ligand
EP1080724A4 (en) COMPOSITIONS FOR REDUCING MTP ACTIVITY
MY136546A (en) A pharmaceutical component based on human parathyroid harmone and a pharmaceutical composition for intranasal administration comprising the component
DE60236330D1 (de) Biologisch aktive Peptide
EP1557466A4 (en) TUMORANT PROPERTIES AND USE THEREOF
WO2003017938A3 (en) Conjugates targeted to target receptors
WO2003092736A3 (en) Peptide nucleic acid conjugates with transporter peptides
TW200503748A (en) Biologically active peptide comprising tyrosyl-seryl-valine (YSV)

Legal Events

Date Code Title Description
FA Abandonment or withdrawal