MXPA05005919A - Composiciones de ifosfamida para la administracion parenteral, y un proceso para su preparacion. - Google Patents

Composiciones de ifosfamida para la administracion parenteral, y un proceso para su preparacion.

Info

Publication number
MXPA05005919A
MXPA05005919A MXPA05005919A MXPA05005919A MXPA05005919A MX PA05005919 A MXPA05005919 A MX PA05005919A MX PA05005919 A MXPA05005919 A MX PA05005919A MX PA05005919 A MXPA05005919 A MX PA05005919A MX PA05005919 A MXPA05005919 A MX PA05005919A
Authority
MX
Mexico
Prior art keywords
preparation
compositions
parenteral administration
ifosfamide
ifosfamide compositions
Prior art date
Application number
MXPA05005919A
Other languages
English (en)
Inventor
Subbappa Praveen Kumar
Original Assignee
Bharat Serums & Vaccines Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bharat Serums & Vaccines Ltd filed Critical Bharat Serums & Vaccines Ltd
Publication of MXPA05005919A publication Critical patent/MXPA05005919A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
    • C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
    • C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Saccharide Compounds (AREA)

Abstract

La presente invencion proporciona composiciones acuosas de ifosfamida y un proceso para su preparacion, en donde las composiciones tienen una toxicidad reducida sobre y antes del uso concomitante del agente uroprotector, Mesna. Las composiciones acuosas de ifosfamida se pueden preparar en una concentracion tan alta como de 1100 mg/ml.
MXPA05005919A 2002-12-02 2003-12-02 Composiciones de ifosfamida para la administracion parenteral, y un proceso para su preparacion. MXPA05005919A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN785MU2002 2002-12-02
PCT/IN2003/000376 WO2004050012A2 (en) 2002-12-02 2003-12-02 Ifosfamide compositions for parenteral administration and a process for their preparation

Publications (1)

Publication Number Publication Date
MXPA05005919A true MXPA05005919A (es) 2005-09-21

Family

ID=32448836

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05005919A MXPA05005919A (es) 2002-12-02 2003-12-02 Composiciones de ifosfamida para la administracion parenteral, y un proceso para su preparacion.

Country Status (16)

Country Link
EP (1) EP1569663B1 (es)
JP (1) JP4611029B2 (es)
KR (1) KR101066181B1 (es)
CN (1) CN100463678C (es)
AT (1) ATE465744T1 (es)
AU (1) AU2003302579B2 (es)
BR (1) BR0316968A (es)
CA (1) CA2507848A1 (es)
DE (1) DE60332385D1 (es)
EA (1) EA012368B1 (es)
ES (1) ES2342380T3 (es)
IL (1) IL168849A (es)
MX (1) MXPA05005919A (es)
NZ (1) NZ540484A (es)
WO (1) WO2004050012A2 (es)
ZA (1) ZA200504437B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102573500A (zh) 2009-08-06 2012-07-11 纽拉尔图斯制药公司 巨噬细胞相关疾病的治疗

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3584522D1 (de) * 1984-12-14 1991-11-28 Gergely Gerhard Teilchen aus einer hydrophoben oder schwerloeslichen substanz und verfahren zu ihrer hydrophilisierung.
NO873860L (no) * 1986-10-31 1988-05-02 Asta Pharma Ag Ifosfamid-lyofilisat og fremgangsmaate til deres fremstilling.
US5002935A (en) * 1987-12-30 1991-03-26 University Of Florida Improvements in redox systems for brain-targeted drug delivery
ES2040394T3 (es) * 1988-03-19 1993-10-16 Asta Medica Aktiengesellschaft Procedimiento para preparar un material liofilizado de ifosfamida y mesna.
IE62095B1 (en) * 1988-03-29 1994-12-14 Univ Florida Pharmaceutical formulations for parenteral use
EP0491812A4 (en) * 1989-09-14 1992-11-04 Australian Commercial Research & Development Limited Drug delivery compositions
US5227373A (en) * 1991-10-23 1993-07-13 Bristol-Myers Squibb Co. Lyophilized ifosfamide compositions
ZA949182B (en) * 1993-12-02 1995-07-26 South African Druggists Ltd Pharmaceutical composition
DE19529057B4 (de) * 1995-08-08 2007-12-13 Baxter Healthcare S.A. Ifosfamid-Lyophilisat-Zubereitungen
AUPQ849900A0 (en) 2000-06-30 2000-07-27 Dbl Australia Pty Ltd. Injectable composition
CA2470472A1 (en) * 2001-12-13 2003-06-26 Sicor Inc. Aqueous ifosfamide composition
NZ538584A (en) * 2002-09-05 2007-05-31 Bharat Serums & Vaccines Ltd Stable liquid composition of oxazaphosphorine, mesna and etherified beta-cyclodextrin
US7199111B2 (en) * 2002-12-02 2007-04-03 Bharat Serums & Vaccines Ltd. Aqueous ifosfamide compositions for parenteral administration and a process for their preparations

Also Published As

Publication number Publication date
BR0316968A (pt) 2005-10-25
WO2004050012A3 (en) 2004-10-21
ZA200504437B (en) 2006-07-26
EP1569663A2 (en) 2005-09-07
EP1569663B1 (en) 2010-04-28
EP1569663A4 (en) 2007-05-23
AU2003302579B2 (en) 2008-09-18
CA2507848A1 (en) 2004-06-17
CN100463678C (zh) 2009-02-25
DE60332385D1 (de) 2010-06-10
EA200500763A1 (ru) 2006-12-29
ES2342380T3 (es) 2010-07-06
AU2003302579A1 (en) 2004-06-23
KR101066181B1 (ko) 2011-09-20
NZ540484A (en) 2008-03-28
JP4611029B2 (ja) 2011-01-12
ATE465744T1 (de) 2010-05-15
EA012368B1 (ru) 2009-10-30
JP2006512329A (ja) 2006-04-13
KR20050089153A (ko) 2005-09-07
CN1744904A (zh) 2006-03-08
WO2004050012A2 (en) 2004-06-17
IL168849A (en) 2009-02-11

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