MXPA05004880A - Precursor de n - acetilgalactosamina - 4 - sulfatasa, metodos de tratamiento que utilizan dicha enzima y metodos para producir y purificar dicha enzima. - Google Patents

Precursor de n - acetilgalactosamina - 4 - sulfatasa, metodos de tratamiento que utilizan dicha enzima y metodos para producir y purificar dicha enzima.

Info

Publication number
MXPA05004880A
MXPA05004880A MXPA05004880A MXPA05004880A MXPA05004880A MX PA05004880 A MXPA05004880 A MX PA05004880A MX PA05004880 A MXPA05004880 A MX PA05004880A MX PA05004880 A MXPA05004880 A MX PA05004880A MX PA05004880 A MXPA05004880 A MX PA05004880A
Authority
MX
Mexico
Prior art keywords
acetylgalactosamine
sulphatase
precursor
fluid
enzyme
Prior art date
Application number
MXPA05004880A
Other languages
English (en)
Spanish (es)
Inventor
Sweidler Stuart
Original Assignee
Biomarin Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomarin Pharm Inc filed Critical Biomarin Pharm Inc
Publication of MXPA05004880A publication Critical patent/MXPA05004880A/es

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804Affinity chromatography
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32Bonded phase chromatography
    • B01D15/325Reversed phase
    • B01D15/327Reversed phase with hydrophobic interaction
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804Affinity chromatography
    • B01D15/3828Ligand exchange chromatography, e.g. complexation, chelation or metal interaction chromatography
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/06Sulfuric ester hydrolases (3.1.6)
    • C12Y301/06012N-Acetylgalactosamine-4-sulfatase (3.1.6.12)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
MXPA05004880A 2002-11-07 2003-11-07 Precursor de n - acetilgalactosamina - 4 - sulfatasa, metodos de tratamiento que utilizan dicha enzima y metodos para producir y purificar dicha enzima. MXPA05004880A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/290,908 US6866844B2 (en) 2002-11-07 2002-11-07 Precursor N-acetylgalactosamine-4-sulfatase, methods of treatment using said enzyme and methods for producing and purifying said enzyme
PCT/US2003/035510 WO2004043373A2 (en) 2002-11-07 2003-11-07 Precursor n-acetylgalactosamine-4-sulfatase, methods of treatment using said enzyme and methods for producing and purifying said enzyme

Publications (1)

Publication Number Publication Date
MXPA05004880A true MXPA05004880A (es) 2005-07-22

Family

ID=32312121

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05004880A MXPA05004880A (es) 2002-11-07 2003-11-07 Precursor de n - acetilgalactosamina - 4 - sulfatasa, metodos de tratamiento que utilizan dicha enzima y metodos para producir y purificar dicha enzima.

Country Status (17)

Country Link
US (1) US6866844B2 (cg-RX-API-DMAC7.html)
EP (2) EP2327414B1 (cg-RX-API-DMAC7.html)
JP (1) JP4459059B2 (cg-RX-API-DMAC7.html)
CN (1) CN100374157C (cg-RX-API-DMAC7.html)
AR (1) AR042019A1 (cg-RX-API-DMAC7.html)
AU (1) AU2003290642B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0316039B1 (cg-RX-API-DMAC7.html)
CA (1) CA2502928C (cg-RX-API-DMAC7.html)
CY (1) CY1116164T1 (cg-RX-API-DMAC7.html)
DK (1) DK2327414T3 (cg-RX-API-DMAC7.html)
ES (2) ES2533770T3 (cg-RX-API-DMAC7.html)
IL (1) IL168435A (cg-RX-API-DMAC7.html)
MX (1) MXPA05004880A (cg-RX-API-DMAC7.html)
PT (2) PT2327414E (cg-RX-API-DMAC7.html)
SI (1) SI2327414T1 (cg-RX-API-DMAC7.html)
TW (1) TWI327919B (cg-RX-API-DMAC7.html)
WO (1) WO2004043373A2 (cg-RX-API-DMAC7.html)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6972124B2 (en) * 2000-05-01 2005-12-06 Biomarin Pharmaceuticals Inc. Precursor of N-acetylgalactosamine-4-sulfatase, methods of treatment using said enzyme and methods for producing and purifying said enzyme
JP2009529885A (ja) * 2006-03-17 2009-08-27 バイオマリン ファーマシューティカル インコーポレイテッド リソソーム酵素に対する抗体の検出のためのアッセイ
CN101539550B (zh) * 2009-04-28 2012-05-23 李绍平 用于多糖的定性与定量分析方法
CN103282046B (zh) 2010-06-25 2015-05-13 夏尔人类遗传性治疗公司 芳基硫酸酯酶 a cns 递送的方法和组合物
UA129740C2 (uk) 2010-06-25 2025-07-23 Такеда Фармасьютікал Компані Лімітед Застосування композиції, що включає білок арилсульфатази а (аса)
WO2012022688A1 (de) * 2010-08-20 2012-02-23 Boehringer Ingelheim International Gmbh Verfahren zur inaktivierung von proteasen in einer aus einer zellkultur gewonnen flüssigkeit durch ph änderung
WO2013094579A1 (ja) 2011-12-20 2013-06-27 日本ケミカルリサーチ株式会社 ホルミルグリシン残基の分析法
WO2013096899A2 (en) 2011-12-23 2013-06-27 Shire Human Genetic Therapies, Inc. Stable formulations for cns delivery of arylsulfatase a
WO2015035180A1 (en) 2013-09-05 2015-03-12 Genentech, Inc. Method for chromatography reuse
FR3011468B1 (fr) * 2013-10-04 2015-12-04 Inventiva Utilisation de l'odiparcil dans le traitement d'une mucopolysaccharidose
KR102286260B1 (ko) 2017-08-31 2021-08-05 주식회사 녹십자 설파타아제 단백질을 정제하는 방법
AR119264A1 (es) * 2019-06-05 2021-12-09 Genentech Inc Método para reutilización de cromatografía

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL281225A (cg-RX-API-DMAC7.html) 1961-07-20
US3472931A (en) 1969-01-17 1969-10-14 Foster Milburn Co Percutaneous absorption with lower alkyl amides
US3891757A (en) 1971-11-11 1975-06-24 Alza Corp Anaesthetic topical and percutaneous administration with selected promoters
SE387536B (sv) 1973-03-13 1976-09-13 Astra Laekemedel Ab Forfarande for framstellning av en lokalanestetisk beredning
WO2001083722A2 (en) 2000-05-01 2001-11-08 Biomarin Pharmaceuticals Enzymes useful for treating and methods for treating mps-vi and cells lines for producing such enzymes recombinantly

Also Published As

Publication number Publication date
DK2327414T3 (en) 2015-04-13
CA2502928C (en) 2013-07-16
AU2003290642B2 (en) 2008-07-10
CN1726046A (zh) 2006-01-25
CN100374157C (zh) 2008-03-12
WO2004043373A3 (en) 2004-08-05
CA2502928A1 (en) 2004-05-27
TWI327919B (en) 2010-08-01
US6866844B2 (en) 2005-03-15
BRPI0316039B1 (pt) 2017-08-29
JP2006510356A (ja) 2006-03-30
HK1157215A1 (en) 2012-06-29
EP1565209B1 (en) 2013-11-06
TW200427459A (en) 2004-12-16
WO2004043373A2 (en) 2004-05-27
JP4459059B2 (ja) 2010-04-28
US20040101524A1 (en) 2004-05-27
AU2003290642A1 (en) 2004-06-03
ES2533770T3 (es) 2015-04-15
EP1565209A4 (en) 2008-01-02
AR042019A1 (es) 2005-06-08
PT2327414E (pt) 2015-04-13
PT1565209E (pt) 2014-02-13
BRPI0316039B8 (cg-RX-API-DMAC7.html) 2021-05-25
EP1565209A2 (en) 2005-08-24
EP2327414B1 (en) 2015-01-07
ES2445028T3 (es) 2014-02-27
CY1116164T1 (el) 2017-02-08
IL168435A (en) 2014-07-31
EP2327414A1 (en) 2011-06-01
BR0316039A (pt) 2005-09-13
SI2327414T1 (sl) 2015-05-29

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