MXPA05004804A - Antigenos de p153 y p156 para el inmunodiagnostico de erliquiosis canina y humana y usos de los mismos. - Google Patents

Antigenos de p153 y p156 para el inmunodiagnostico de erliquiosis canina y humana y usos de los mismos.

Info

Publication number
MXPA05004804A
MXPA05004804A MXPA05004804A MXPA05004804A MXPA05004804A MX PA05004804 A MXPA05004804 A MX PA05004804A MX PA05004804 A MXPA05004804 A MX PA05004804A MX PA05004804 A MXPA05004804 A MX PA05004804A MX PA05004804 A MXPA05004804 A MX PA05004804A
Authority
MX
Mexico
Prior art keywords
immunodiagnosis
canine
antigens
ehrlichioses
human
Prior art date
Application number
MXPA05004804A
Other languages
English (en)
Inventor
Jere W Mcbride
Original Assignee
Res Dev Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Dev Foundation filed Critical Res Dev Foundation
Publication of MXPA05004804A publication Critical patent/MXPA05004804A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/29—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Richettsiales (O)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/825—Bacteria

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Se clonaron secuencias que codifican dos glucoproteinas inmunoreactivas de Ehrlichia canis (gen p153) y Ehrlichia chaffeensis (gen p156); estas dos glicoproteinas son ortologos inmunoreactivos especificos de especie que son utiles como vacunas subunitarias y para diagnosticos serologicos y moleculares para E. canis y E. chaffeensis.
MXPA05004804A 2002-11-04 2003-11-04 Antigenos de p153 y p156 para el inmunodiagnostico de erliquiosis canina y humana y usos de los mismos. MXPA05004804A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42357302P 2002-11-04 2002-11-04
PCT/US2003/034916 WO2004042037A1 (en) 2002-11-04 2003-11-04 P153 and p156 antigens for the immunodiagnosis of canine and human ehrlichioses and uses thereof

Publications (1)

Publication Number Publication Date
MXPA05004804A true MXPA05004804A (es) 2005-12-05

Family

ID=32312680

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05004804A MXPA05004804A (es) 2002-11-04 2003-11-04 Antigenos de p153 y p156 para el inmunodiagnostico de erliquiosis canina y humana y usos de los mismos.

Country Status (13)

Country Link
US (2) US7204992B2 (es)
EP (1) EP1581638B1 (es)
JP (1) JP4494974B2 (es)
KR (1) KR101063177B1 (es)
CN (2) CN101294162B (es)
AT (1) ATE372378T1 (es)
AU (1) AU2003290575B2 (es)
BR (1) BRPI0315980B1 (es)
CA (1) CA2504762A1 (es)
DE (1) DE60316189T2 (es)
ES (1) ES2293057T3 (es)
MX (1) MXPA05004804A (es)
WO (1) WO2004042037A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7842474B2 (en) 2005-04-04 2010-11-30 Idexx Laboratories, Inc. Ehrlichia canis DIVA (differentiate infected from vaccinated animals)
ES2715280T3 (es) * 2005-04-04 2019-06-03 Idexx Lab Inc DIVA de Erlichia canis (Diferenciación entre Animales Vacunados e Infectados)
WO2006138509A2 (en) * 2005-06-16 2006-12-28 Research Development Foundation Immunoreactive protein orthologs of ehrlichia canis and e. chaffeensis
US8361480B2 (en) 2007-09-11 2013-01-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Attenuated ehrlichiosis vaccine
BRPI0817202B1 (pt) 2007-09-21 2018-11-21 Idexx Lab Inc polipeptídeo purificado e método de detecção de anticorpos que se ligam especificamente a um polipeptídio do ehrlichia chaffeensis em uma amostra em teste
EP2045816A1 (en) * 2007-10-01 2009-04-08 Paul Scherrer Institut Fast readout method and swiched capacitor array circuitry for waveform digitizing
WO2009059170A2 (en) * 2007-10-31 2009-05-07 Idexx Laboratories, Inc. Ehrlichia canis diva (differentiate infection from vaccinated animals)
EP2944649A1 (en) 2008-01-10 2015-11-18 Research Development Foundation Vaccines and diagnostics for the ehrlichioses
KR101892182B1 (ko) 2009-11-20 2018-08-24 아박시스, 인크. 에를리키아 항체의 검출을 위한 펩티드, 장치 및 방법
PT2588133T (pt) * 2010-07-02 2018-03-05 Intervet Int Bv Vacina contra ehrlichia canis e métodos associados
EP2906950B1 (en) 2012-10-11 2018-03-21 Abaxis, Inc. Peptides, devices, and methods for the detection of ehrlichia antibodies
US9194870B2 (en) 2014-01-21 2015-11-24 Abaxis, Inc. Peptides, devices, and methods for the detection of Anaplasma antibodies
US9442112B2 (en) 2014-04-04 2016-09-13 Abaxis, Inc. Compositions and methods for identifying Ehrlichia species
WO2021011456A1 (en) * 2019-07-12 2021-01-21 Research Development Foundation Ehrlichia vaccines and immunogenic compositions

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6653128B2 (en) * 1996-10-17 2003-11-25 University Of Florida Nucleic acid vaccines against rickettsial diseases and methods of use
US6207169B1 (en) * 1997-03-21 2001-03-27 Corixa Corporation Compounds and methods for the diagnosis and treatment of Ehrlichia infection
US6403093B1 (en) * 1997-03-21 2002-06-11 Mayo Foundation For Medical Education And Research Methods to detect granulocytic ehrlichiosis
US6436399B1 (en) * 1998-04-09 2002-08-20 The Ohio State University Research Foundation Nucleic acid encoding the major outer membrane protein of the causative agent of human granulocytic ehrlichiosis and peptides encoded thereby
WO1999052370A1 (en) * 1998-04-09 1999-10-21 The Ohio State Research Foundation Nucleic acids encoding outer membrane protein of human granulocytic ehrlichiosis agent
US6043085A (en) * 1998-08-27 2000-03-28 Research Development Foundation Ehrlichia canis 120-kDa immunodominant antigenic protein and gene
US6544517B1 (en) * 1998-09-18 2003-04-08 The Ohio State University Research Foundation Outer membrane protein of Ehrlichia canis and Ehrlichia chaffeensis
US6355777B1 (en) * 2000-04-28 2002-03-12 Research Development Foundation P43 antigen for the immunodiagnosis of canine ehrlichiosis and uses thereof
US6512005B2 (en) * 2001-02-28 2003-01-28 Taro Pharmaceutical Industries, Ltd. Process for synthesis of pure warfarin acid, warfarin alkali metal salts and corresponding clathrates

Also Published As

Publication number Publication date
EP1581638A4 (en) 2005-12-28
AU2003290575B2 (en) 2009-10-29
ES2293057T3 (es) 2008-03-16
JP2006505270A (ja) 2006-02-16
KR101063177B1 (ko) 2011-09-08
US20040121433A1 (en) 2004-06-24
CA2504762A1 (en) 2004-05-21
BRPI0315980B1 (pt) 2016-03-29
BR0315980A (pt) 2005-09-20
CN101294162A (zh) 2008-10-29
DE60316189T2 (de) 2007-12-20
DE60316189D1 (de) 2007-10-18
ATE372378T1 (de) 2007-09-15
US7754224B2 (en) 2010-07-13
US7204992B2 (en) 2007-04-17
AU2003290575A1 (en) 2004-06-07
KR20050084679A (ko) 2005-08-26
CN100386430C (zh) 2008-05-07
CN101294162B (zh) 2011-03-30
CN1735684A (zh) 2006-02-15
US20070218082A1 (en) 2007-09-20
EP1581638B1 (en) 2007-09-05
JP4494974B2 (ja) 2010-06-30
WO2004042037A1 (en) 2004-05-21
EP1581638A1 (en) 2005-10-05

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