MXPA05004804A - Antigenos de p153 y p156 para el inmunodiagnostico de erliquiosis canina y humana y usos de los mismos. - Google Patents

Antigenos de p153 y p156 para el inmunodiagnostico de erliquiosis canina y humana y usos de los mismos.

Info

Publication number
MXPA05004804A
MXPA05004804A MXPA05004804A MXPA05004804A MXPA05004804A MX PA05004804 A MXPA05004804 A MX PA05004804A MX PA05004804 A MXPA05004804 A MX PA05004804A MX PA05004804 A MXPA05004804 A MX PA05004804A MX PA05004804 A MXPA05004804 A MX PA05004804A
Authority
MX
Mexico
Prior art keywords
immunodiagnosis
canine
antigens
ehrlichioses
human
Prior art date
Application number
MXPA05004804A
Other languages
English (en)
Inventor
Jere W Mcbride
Original Assignee
Res Dev Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Dev Foundation filed Critical Res Dev Foundation
Publication of MXPA05004804A publication Critical patent/MXPA05004804A/es

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/29Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Richettsiales (O)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • Y10S530/825Bacteria

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Se clonaron secuencias que codifican dos glucoproteinas inmunoreactivas de Ehrlichia canis (gen p153) y Ehrlichia chaffeensis (gen p156); estas dos glicoproteinas son ortologos inmunoreactivos especificos de especie que son utiles como vacunas subunitarias y para diagnosticos serologicos y moleculares para E. canis y E. chaffeensis.
MXPA05004804A 2002-11-04 2003-11-04 Antigenos de p153 y p156 para el inmunodiagnostico de erliquiosis canina y humana y usos de los mismos. MXPA05004804A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42357302P 2002-11-04 2002-11-04
PCT/US2003/034916 WO2004042037A1 (en) 2002-11-04 2003-11-04 P153 and p156 antigens for the immunodiagnosis of canine and human ehrlichioses and uses thereof

Publications (1)

Publication Number Publication Date
MXPA05004804A true MXPA05004804A (es) 2005-12-05

Family

ID=32312680

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05004804A MXPA05004804A (es) 2002-11-04 2003-11-04 Antigenos de p153 y p156 para el inmunodiagnostico de erliquiosis canina y humana y usos de los mismos.

Country Status (13)

Country Link
US (2) US7204992B2 (es)
EP (1) EP1581638B1 (es)
JP (1) JP4494974B2 (es)
KR (1) KR101063177B1 (es)
CN (2) CN100386430C (es)
AT (1) ATE372378T1 (es)
AU (1) AU2003290575B2 (es)
BR (1) BRPI0315980B1 (es)
CA (1) CA2504762A1 (es)
DE (1) DE60316189T2 (es)
ES (1) ES2293057T3 (es)
MX (1) MXPA05004804A (es)
WO (1) WO2004042037A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006107924A2 (en) * 2005-04-04 2006-10-12 Idexx Laboratories, Inc. Ehrlichia canis diva (differentiate infected from vaccinated animals)
US7842474B2 (en) 2005-04-04 2010-11-30 Idexx Laboratories, Inc. Ehrlichia canis DIVA (differentiate infected from vaccinated animals)
MX2007016189A (es) 2005-06-16 2008-03-10 Res Dev Foundation Ortologos de proteinas inmunoreactivas de ehrlichia canis y e. chaffeensis.
PT2187958T (pt) 2007-09-11 2017-03-17 Yissum Res Dev Company Of The Hebrew Univ Of Jerusalem Vacina atenuada de erliquiose
JP2011501653A (ja) 2007-09-21 2011-01-13 アイデックス ラボラトリーズ インコーポレイテッド エーリキア・シャフェンシス(EhrlichiaChaffeensis)(VLPT)の検出のための方法および組成物
EP2045816A1 (en) * 2007-10-01 2009-04-08 Paul Scherrer Institut Fast readout method and swiched capacitor array circuitry for waveform digitizing
EP2215477B1 (en) * 2007-10-31 2019-01-16 IDEXX Laboratories Inc Ehrlichia canis diva (differentiate infection from vaccinated animals)
WO2009102509A2 (en) 2008-01-10 2009-08-20 Research Development Foundation Vaccines and diagnostics for the ehrlichioses
ES2596952T3 (es) 2009-11-20 2017-01-13 Abaxis, Inc. Péptidos, dispositivos y procedimientos para la detección de anticuerpos de Ehrlichia
PT2588133T (pt) * 2010-07-02 2018-03-05 Intervet Int Bv Vacina contra ehrlichia canis e métodos associados
ES2668863T3 (es) 2012-10-11 2018-05-22 Abaxis, Inc. Péptidos, dispositivos y métodos para la detección de anticuerpos de Ehrlichia
US9194870B2 (en) 2014-01-21 2015-11-24 Abaxis, Inc. Peptides, devices, and methods for the detection of Anaplasma antibodies
US9442112B2 (en) 2014-04-04 2016-09-13 Abaxis, Inc. Compositions and methods for identifying Ehrlichia species
BR112022000347A2 (pt) * 2019-07-12 2022-04-12 Res Found Dev Vacinas de ehrlichia e composições imunogênicas

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6653128B2 (en) * 1996-10-17 2003-11-25 University Of Florida Nucleic acid vaccines against rickettsial diseases and methods of use
US6207169B1 (en) * 1997-03-21 2001-03-27 Corixa Corporation Compounds and methods for the diagnosis and treatment of Ehrlichia infection
US6403093B1 (en) * 1997-03-21 2002-06-11 Mayo Foundation For Medical Education And Research Methods to detect granulocytic ehrlichiosis
EP1069827A4 (en) * 1998-04-09 2003-06-18 Ohio State Res Found NUCLEIC ACIDS ENCODING AN EXTERNAL MEMBRANE PROTEIN OF HUMAN GRANULOCYTE EHRLICHIOSIS AGENT
US6436399B1 (en) * 1998-04-09 2002-08-20 The Ohio State University Research Foundation Nucleic acid encoding the major outer membrane protein of the causative agent of human granulocytic ehrlichiosis and peptides encoded thereby
US6043085A (en) * 1998-08-27 2000-03-28 Research Development Foundation Ehrlichia canis 120-kDa immunodominant antigenic protein and gene
US6544517B1 (en) * 1998-09-18 2003-04-08 The Ohio State University Research Foundation Outer membrane protein of Ehrlichia canis and Ehrlichia chaffeensis
US6355777B1 (en) * 2000-04-28 2002-03-12 Research Development Foundation P43 antigen for the immunodiagnosis of canine ehrlichiosis and uses thereof
US6512005B2 (en) * 2001-02-28 2003-01-28 Taro Pharmaceutical Industries, Ltd. Process for synthesis of pure warfarin acid, warfarin alkali metal salts and corresponding clathrates

Also Published As

Publication number Publication date
US7204992B2 (en) 2007-04-17
AU2003290575B2 (en) 2009-10-29
DE60316189D1 (de) 2007-10-18
EP1581638A1 (en) 2005-10-05
CN101294162B (zh) 2011-03-30
US7754224B2 (en) 2010-07-13
CA2504762A1 (en) 2004-05-21
DE60316189T2 (de) 2007-12-20
KR101063177B1 (ko) 2011-09-08
EP1581638B1 (en) 2007-09-05
KR20050084679A (ko) 2005-08-26
BRPI0315980B1 (pt) 2016-03-29
CN100386430C (zh) 2008-05-07
CN1735684A (zh) 2006-02-15
ES2293057T3 (es) 2008-03-16
ATE372378T1 (de) 2007-09-15
JP2006505270A (ja) 2006-02-16
US20070218082A1 (en) 2007-09-20
CN101294162A (zh) 2008-10-29
JP4494974B2 (ja) 2010-06-30
WO2004042037A1 (en) 2004-05-21
AU2003290575A1 (en) 2004-06-07
US20040121433A1 (en) 2004-06-24
EP1581638A4 (en) 2005-12-28
BR0315980A (pt) 2005-09-20

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