HUP0303655A2 - Proliferatív ileitis elleni hatékonyabb vakcinák, előállításuk és alkalmazásuk - Google Patents
Proliferatív ileitis elleni hatékonyabb vakcinák, előállításuk és alkalmazásukInfo
- Publication number
- HUP0303655A2 HUP0303655A2 HU0303655A HUP0303655A HUP0303655A2 HU P0303655 A2 HUP0303655 A2 HU P0303655A2 HU 0303655 A HU0303655 A HU 0303655A HU P0303655 A HUP0303655 A HU P0303655A HU P0303655 A2 HUP0303655 A2 HU P0303655A2
- Authority
- HU
- Hungary
- Prior art keywords
- intracellularis
- proliferative ileitis
- making
- methods
- same
- Prior art date
Links
- 208000009326 ileitis Diseases 0.000 title abstract 4
- 230000002062 proliferating effect Effects 0.000 title abstract 4
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 241001148567 Lawsonia intracellularis Species 0.000 abstract 7
- 241000282887 Suidae Species 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 239000000284 extract Substances 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
A találmány tárgyát általánosságban sertések Lawsonia intracellularisáltal okozott proliferatív ileitistől való megvédésére szolgálóvakcinák és diagnosztikumok előállítása képe. A találmány szerintiproliferatív ileitis elleni vakcinák tartalmazhatnak teljes L.intracellularis baktériumokat, L. intracellularis sejtkivonatokat,protektív L. intracellularis immunogén alegységeket rekombináns L.intracellularis immunogéneket, valamint csupasz L. intracellularisDNS-t. A találmány tárgyát képezik továbbá L. intracellularisnövekedését semlegesítő, valamint proliferatív ileitis diagnózisábanalkalmazható monoklonális antitestek is. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67710800A | 2000-09-29 | 2000-09-29 | |
PCT/US2001/030284 WO2002026250A2 (en) | 2000-09-29 | 2001-09-27 | Vaccines for proliferative ileitis |
Publications (1)
Publication Number | Publication Date |
---|---|
HUP0303655A2 true HUP0303655A2 (hu) | 2004-03-01 |
Family
ID=24717358
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0303655A HUP0303655A2 (hu) | 2000-09-29 | 2001-09-27 | Proliferatív ileitis elleni hatékonyabb vakcinák, előállításuk és alkalmazásuk |
Country Status (7)
Country | Link |
---|---|
US (1) | US20060193874A1 (hu) |
EP (1) | EP1324768A2 (hu) |
JP (1) | JP2004529854A (hu) |
AU (2) | AU9315101A (hu) |
CA (1) | CA2423588A1 (hu) |
HU (1) | HUP0303655A2 (hu) |
WO (1) | WO2002026250A2 (hu) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0413857A (pt) * | 2003-09-12 | 2006-10-24 | Akzo Nobel Nv | seqüência de ácido nucleico, fragmento de dna, molécula de dna recombinante, veìculo recombinante vivo, célula hispedeira, proteìna de lawsonia intracellularis, uso de uma proteìna de lawsonia intracellularis, vacina para combater infecções por lawsonia intracellularis, método para a preparação de uma vacina, e, teste diagnóstico |
EP1709067B1 (en) * | 2004-01-22 | 2010-06-09 | Intervet International BV | Lawsonia intracellularis subunit vaccines |
MY146476A (en) | 2004-06-24 | 2012-08-15 | Boehringer Ingelheim Vetmed | Method of diagnosing lawsonia intracellularis |
EP1609870A1 (en) * | 2004-06-24 | 2005-12-28 | Boehringer Ingelheim Vetmedica Gmbh | Method of diagnosing lawsonia intracellularis |
US7550270B2 (en) * | 2004-08-13 | 2009-06-23 | Boehringer Ingelheim Vetmedica, Inc. | Ileitis diagnostic assay |
US8834891B2 (en) | 2005-03-14 | 2014-09-16 | Boehringer Ingelheim Vetmedica, Inc. | Immunogenic compositions comprising Lawsonia intracellularis |
US8398994B2 (en) | 2005-07-15 | 2013-03-19 | Boehringer Ingelheim Vetmedica, Inc. | Lawsonia vaccine and methods of use thereof |
US8470336B2 (en) | 2006-05-25 | 2013-06-25 | Boehringer Ingelheim Vetmedica, Inc. | Vaccination of young animals against Lawsonia intracellularis infections |
US20100129397A1 (en) | 2006-12-11 | 2010-05-27 | Boehringer Ingelheim Vetmedica, Inc. | Effective method of treatment of porcine circovirus and lawsonia intracellularis infections |
US8398970B2 (en) | 2007-09-17 | 2013-03-19 | Boehringer Ingelheim Vetmedica, Inc. | Method of preventing early Lawsonia intracellularis infections |
EP2205718A1 (en) * | 2007-10-12 | 2010-07-14 | Pfizer Inc. | Methods of culturing lawsonia intracellularis |
TWI449533B (zh) | 2008-04-18 | 2014-08-21 | Intervet Int Bv | 防備胞內勞森菌(Lawsonia intracellularis)、豬肺炎黴漿菌(Mycoplasma hyopneumoniae)及豬環狀病毒(Porcine circo virus)用疫苗 |
TWI551295B (zh) | 2008-04-18 | 2016-10-01 | 英特威特國際股份有限公司 | 防備胞內勞森菌(Lawsonia intracellularis)用疫苗 |
US8277650B2 (en) | 2009-03-13 | 2012-10-02 | Terrasep, Llc | Methods and apparatus for centrifugal liquid chromatography |
JP5977594B2 (ja) | 2011-07-19 | 2016-08-24 | 住友化学株式会社 | レジスト組成物及びレジストパターンの製造方法 |
EP3191576A4 (en) * | 2014-09-12 | 2018-04-18 | Anthrogenesis Corporation | Methods for quantifying particulates in cell culture |
JP2018504424A (ja) | 2015-02-04 | 2018-02-15 | インターベット インターナショナル ベー. フェー. | 豚における無症候性ローソニア感染症に対する使用のためのワクチン |
JP2018504423A (ja) | 2015-02-04 | 2018-02-15 | インターベット インターナショナル ベー. フェー. | 豚における無症候性ローソニア感染症に対する使用のためのワクチン |
EP3609533A1 (en) * | 2017-04-13 | 2020-02-19 | Intervet International B.V. | Vaccines containing swine pathogens for associated non-mixed use |
US10792352B2 (en) | 2018-02-28 | 2020-10-06 | Boehringer Ingelheim Vetmedica Gmbh | Method for reducing skatole and/or indole in animals |
CN110468088A (zh) * | 2019-09-26 | 2019-11-19 | 华中农业大学 | 胞内劳森菌的培养方法及应用 |
US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
AU2022375120A1 (en) | 2021-11-01 | 2024-04-11 | Boehringer Ingelheim Vetmedica Gmbh | Immunogenic gel compositions |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5610059A (en) * | 1992-11-09 | 1997-03-11 | University Of Arizona | Etiological agent for porcine enteritis |
US5885823A (en) * | 1995-06-05 | 1999-03-23 | Nobl Laboratories, Inc. | Lawsonia intracellularis cultivation, anti-Lawsonia intracellularis vaccines and diagnostic agents |
US5714375A (en) * | 1995-06-05 | 1998-02-03 | Nobl Laboratories, Inc. | Ileal symbiont intracellularis propagation in suspended host cells |
NZ322398A (en) * | 1995-11-30 | 2000-02-28 | Pig Res & Dev Corp | Vaccine compositions comprising non-pathogenic form of Lawsonia intracellularis, nucleic acid sequences thereof and treatment of intestinal disease |
JP2003521881A (ja) * | 1999-05-13 | 2003-07-22 | オーストラリアン ポーク リミティッド | ローソニア由来の遺伝子及び関連OmpHポリペプチド、ぺプチド及びタンパク質並びにそれらの使用 |
US6605696B1 (en) * | 1999-10-22 | 2003-08-12 | Pfizer, Inc. | Lawsonia intracellularis proteins, and related methods and materials |
-
2001
- 2001-09-27 JP JP2002530080A patent/JP2004529854A/ja not_active Withdrawn
- 2001-09-27 HU HU0303655A patent/HUP0303655A2/hu unknown
- 2001-09-27 WO PCT/US2001/030284 patent/WO2002026250A2/en active IP Right Grant
- 2001-09-27 EP EP01973589A patent/EP1324768A2/en not_active Withdrawn
- 2001-09-27 AU AU9315101A patent/AU9315101A/xx active Pending
- 2001-09-27 CA CA002423588A patent/CA2423588A1/en not_active Abandoned
- 2001-09-27 AU AU2001293151A patent/AU2001293151B8/en not_active Ceased
-
2005
- 2005-07-14 US US11/181,484 patent/US20060193874A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2001293151B2 (en) | 2005-12-01 |
JP2004529854A (ja) | 2004-09-30 |
WO2002026250A3 (en) | 2003-05-01 |
CA2423588A1 (en) | 2002-04-04 |
EP1324768A2 (en) | 2003-07-09 |
WO2002026250A2 (en) | 2002-04-04 |
US20060193874A1 (en) | 2006-08-31 |
AU9315101A (en) | 2002-04-08 |
AU2001293151B8 (en) | 2006-01-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |