MXPA04002510A - Combinacion de opioides selectos con antagonistas de muscarina para tratamiento de incontinencia urinaria. - Google Patents

Combinacion de opioides selectos con antagonistas de muscarina para tratamiento de incontinencia urinaria.

Info

Publication number
MXPA04002510A
MXPA04002510A MXPA04002510A MXPA04002510A MXPA04002510A MX PA04002510 A MXPA04002510 A MX PA04002510A MX PA04002510 A MXPA04002510 A MX PA04002510A MX PA04002510 A MXPA04002510 A MX PA04002510A MX PA04002510 A MXPA04002510 A MX PA04002510A
Authority
MX
Mexico
Prior art keywords
urinary incontinence
combination
treating urinary
opioids
muscarine antagonists
Prior art date
Application number
MXPA04002510A
Other languages
English (en)
Spanish (es)
Inventor
Christoph Thomas
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of MXPA04002510A publication Critical patent/MXPA04002510A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12Antidiuretics, e.g. drugs for diabetes insipidus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MXPA04002510A 2001-09-18 2002-09-18 Combinacion de opioides selectos con antagonistas de muscarina para tratamiento de incontinencia urinaria. MXPA04002510A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10146275A DE10146275A1 (de) 2001-09-18 2001-09-18 Kombination ausgewählter Opioide mit Muscarin-Antagonisten zur Therapie der Harninkontinenz
PCT/EP2002/010460 WO2003024444A1 (de) 2001-09-18 2002-09-18 Kombination ausgewählter opioide mit muscarin-antagonisten zur therapie der harninkontinenz

Publications (1)

Publication Number Publication Date
MXPA04002510A true MXPA04002510A (es) 2004-05-31

Family

ID=7699618

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04002510A MXPA04002510A (es) 2001-09-18 2002-09-18 Combinacion de opioides selectos con antagonistas de muscarina para tratamiento de incontinencia urinaria.

Country Status (21)

Country Link
US (2) US20040242617A1 (https=)
EP (1) EP1429754B1 (https=)
JP (1) JP4511176B2 (https=)
KR (1) KR100891438B1 (https=)
CN (1) CN100384413C (https=)
AT (1) ATE383854T1 (https=)
AU (1) AU2002342707B2 (https=)
BR (1) BR0212714A (https=)
CA (1) CA2460655C (https=)
DE (2) DE10146275A1 (https=)
EC (1) ECSP045025A (https=)
ES (1) ES2299608T3 (https=)
HU (1) HUP0401485A3 (https=)
IL (2) IL160894A0 (https=)
MX (1) MXPA04002510A (https=)
NO (1) NO333016B1 (https=)
NZ (1) NZ531777A (https=)
PL (1) PL209272B1 (https=)
RU (1) RU2305562C2 (https=)
WO (1) WO2003024444A1 (https=)
ZA (1) ZA200402853B (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10146275A1 (de) 2001-09-18 2003-04-24 Gruenenthal Gmbh Kombination ausgewählter Opioide mit Muscarin-Antagonisten zur Therapie der Harninkontinenz
DE10224108A1 (de) * 2002-05-29 2004-01-29 Grünenthal GmbH 1-Dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol enthaltendes Arzneimiitel mit verzögerter Wirkstofffreisetzung
US7410965B2 (en) 2002-05-29 2008-08-12 Gruenenthal Gmbh Delayed release pharmaceutical composition containing 1-dimethyl-amino-3-(3-methoxyphenyl)-2-methyl-pentan-3-ol
DE10224556A1 (de) * 2002-05-31 2004-01-08 Grünenthal GmbH 1-Dimethylamino- 3-(3-methoxy-phenyl)2-methyl-pentan-3-ol entaltendes Arzneimittel in verschiedenen Formulierungen
ES2288641T3 (es) * 2002-12-20 2008-01-16 Dynogen Pharmaceuticals Inc. Metodo para tratar trastornos indoloros de la vejiga usando moduladores de canales del calcio de la subunidad alfa2-delta.
DE602004003172T2 (de) * 2003-03-21 2007-09-27 Dynogen Pharmaceuticals Inc., Waltham Verfahren zur behandlung von erkrankungen der unteren harnwege mit antimuskarinika und mit modulatoren der alpha-2-delta untereinheit des kalziumkanals
DE10356362A1 (de) * 2003-11-28 2005-06-23 Grünenthal GmbH Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie von Angststörungen
AU2005245403B2 (en) * 2004-05-14 2012-04-19 Janssen Pharmaceutica N.V. Carboxamido opioid compounds
DE102005009217A1 (de) * 2005-02-25 2006-08-31 Grünenthal GmbH Phosphatsalze der 6-Dimethylaminomethyl-1-(3-methoxyphenyl)-1,3-dihydroxy-cyclohexanverbindungen
US20070032551A1 (en) * 2005-07-22 2007-02-08 Gruenenthal Gmbh Salt of dimethylaminomethyl-phenyl-cyclohexane and crystalline forms thereof
JP5323480B2 (ja) * 2005-07-22 2013-10-23 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 3−[2−(ジメチルアミノ)メチル−(シクロヘキシ−1−イル)]−フェノールのHCl多形体
US7884247B2 (en) * 2005-07-22 2011-02-08 Gruenenthal Gmbh Salt of dimethylaminomethyl-phenyl-cyclohexane and crystalline forms thereof
DE102007022790A1 (de) 2007-05-11 2008-11-20 Grünenthal GmbH Axomadol zur Schmerzbehandlung bei Arthrose
BRPI0921725A2 (pt) * 2008-10-30 2016-01-05 Grüenthal GmbH formas de dosagem potentes do tapentadol
WO2011110595A1 (de) 2010-03-10 2011-09-15 Grünenthal GmbH Kristalline salze und/oder cokristalle von o-desmethyltramadol
CA2798884C (en) 2010-05-10 2016-09-13 Euro-Celtique S.A. Manufacturing of active-free granules and tablets comprising the same
AU2011252039B2 (en) 2010-05-10 2014-06-12 Euro-Celtique S.A. Pharmaceutical compositions comprising hydromorphone and naloxone
CN103002881B (zh) 2010-05-10 2015-09-02 欧洲凯尔特公司 载有活性剂的颗粒与额外活性剂的组合
CN103040828B (zh) * 2013-01-07 2015-12-02 常州康普药业有限公司 复方地芬诺酯片及其制备方法
WO2015071380A1 (en) 2013-11-13 2015-05-21 Euro-Celtique S.A. Hydromorphone and naloxone for treatment of pain and opioid bowel dysfunction syndrome
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB857194A (en) * 1957-07-05 1960-12-29 Clinical Products Ltd Therapeutic agents comprising ion-exchange resins
NL127065C (https=) 1964-04-22
US5736577A (en) 1995-01-31 1998-04-07 Sepracor, Inc. Methods and compositions for treating urinary incontinence using optically pure (S)-oxybutynin
DE3012837A1 (de) * 1979-04-10 1980-10-30 Sandoz Ag Analgetische und myotonolytische praeparate
DE3129982A1 (de) * 1981-07-29 1983-02-17 Jutta 8200 Rosenheim Meyer "antiallergikum"
US5073560A (en) 1990-07-20 1991-12-17 Fisons Corporation Spiro-isoxazolidine derivatives as cholinergic agents
DE4041559A1 (de) 1990-12-22 1992-06-25 Boehringer Ingelheim Kg Neue wirkstoffkombinationen
SE9202218D0 (sv) * 1992-07-22 1992-07-22 Kabi Pharmacia Ab Pharmacologically active alfa-(tertiary-aminomethyl)-benzenemethanol derivatives, pharmaceutical composition containing them, therapeutical use thereof and processes for their preparation
CN1054850C (zh) * 1993-07-30 2000-07-26 德尔塔药物公司 用于治疗的哌嗪化合物
DE4426245A1 (de) 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
DE69631525T2 (de) * 1995-03-03 2004-12-16 Endo Pharmaceuticals Inc. Verwendung von dextromethorphan oder dextrorphan zur behandlung der harninkontinenz
DE19525137C2 (de) 1995-07-11 2003-02-27 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe
DE19609847A1 (de) * 1996-03-13 1997-09-18 Gruenenthal Gmbh Dimethyl-(3-aryl-but-3-enyl)-aminverbindungen als pharmazeutische Wirkstoffe
JP2000515525A (ja) 1996-07-19 2000-11-21 アベーグ,グンナー 尿と胃腸の疾患の治療におけるs(―)―トルテロジン
EP1005861B1 (en) * 1997-04-11 2005-06-29 Nippon Shinyaku Co., Ltd. Remedies for frequent urination and urinary incontinence
PE20010623A1 (es) * 1999-10-05 2001-07-07 Gruenenthal Chemie Uso de (+)-tramadol y/o o-demetiltramadol para tratamiento de urgencia urinaria incrementada y/o incontinencia urinaria
PT1257277E (pt) * 2000-02-24 2005-09-30 Pharmacia & Upjohn Co Llc Novas combinacoes de farmacos
DE10059412A1 (de) * 2000-11-30 2002-06-13 Gruenenthal Gmbh Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie der Harninkontinenz
DE10146275A1 (de) 2001-09-18 2003-04-24 Gruenenthal Gmbh Kombination ausgewählter Opioide mit Muscarin-Antagonisten zur Therapie der Harninkontinenz

Also Published As

Publication number Publication date
CA2460655A1 (en) 2003-03-27
CN100384413C (zh) 2008-04-30
WO2003024444A1 (de) 2003-03-27
HUP0401485A3 (en) 2008-04-28
DE50211566D1 (de) 2008-03-06
NZ531777A (en) 2006-11-30
IL160894A0 (en) 2004-08-31
ATE383854T1 (de) 2008-02-15
ES2299608T3 (es) 2008-06-01
KR100891438B1 (ko) 2009-04-03
RU2004111788A (ru) 2005-06-10
EP1429754B1 (de) 2008-01-16
JP4511176B2 (ja) 2010-07-28
AU2002342707B2 (en) 2006-10-12
EP1429754A1 (de) 2004-06-23
PL369235A1 (en) 2005-04-18
NO20041059L (no) 2004-05-12
RU2305562C2 (ru) 2007-09-10
BR0212714A (pt) 2004-08-03
ZA200402853B (en) 2005-02-23
HUP0401485A2 (hu) 2004-11-29
NO333016B1 (no) 2013-02-18
HK1075205A1 (zh) 2005-12-09
JP2005507387A (ja) 2005-03-17
DE10146275A1 (de) 2003-04-24
US20120016023A1 (en) 2012-01-19
ECSP045025A (es) 2004-04-28
KR20040044953A (ko) 2004-05-31
US8946290B2 (en) 2015-02-03
IL160894A (en) 2010-04-29
CA2460655C (en) 2012-02-07
US20040242617A1 (en) 2004-12-02
CN1589140A (zh) 2005-03-02
PL209272B1 (pl) 2011-08-31

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