IL160894A0 - Combination of selected opioids with muscarine antagonists for treating urinary incontinence - Google Patents

Combination of selected opioids with muscarine antagonists for treating urinary incontinence

Info

Publication number
IL160894A0
IL160894A0 IL16089402A IL16089402A IL160894A0 IL 160894 A0 IL160894 A0 IL 160894A0 IL 16089402 A IL16089402 A IL 16089402A IL 16089402 A IL16089402 A IL 16089402A IL 160894 A0 IL160894 A0 IL 160894A0
Authority
IL
Israel
Prior art keywords
urinary incontinence
combination
treating urinary
opioids
muscarine antagonists
Prior art date
Application number
IL16089402A
Other languages
English (en)
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of IL160894A0 publication Critical patent/IL160894A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12Antidiuretics, e.g. drugs for diabetes insipidus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL16089402A 2001-09-18 2002-09-18 Combination of selected opioids with muscarine antagonists for treating urinary incontinence IL160894A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10146275A DE10146275A1 (de) 2001-09-18 2001-09-18 Kombination ausgewählter Opioide mit Muscarin-Antagonisten zur Therapie der Harninkontinenz
PCT/EP2002/010460 WO2003024444A1 (de) 2001-09-18 2002-09-18 Kombination ausgewählter opioide mit muscarin-antagonisten zur therapie der harninkontinenz

Publications (1)

Publication Number Publication Date
IL160894A0 true IL160894A0 (en) 2004-08-31

Family

ID=7699618

Family Applications (2)

Application Number Title Priority Date Filing Date
IL16089402A IL160894A0 (en) 2001-09-18 2002-09-18 Combination of selected opioids with muscarine antagonists for treating urinary incontinence
IL160894A IL160894A (en) 2001-09-18 2004-03-16 Combination of selected opioids with muscarine antagonists for treating urinary incontinence

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL160894A IL160894A (en) 2001-09-18 2004-03-16 Combination of selected opioids with muscarine antagonists for treating urinary incontinence

Country Status (22)

Country Link
US (2) US20040242617A1 (xx)
EP (1) EP1429754B1 (xx)
JP (1) JP4511176B2 (xx)
KR (1) KR100891438B1 (xx)
CN (1) CN100384413C (xx)
AT (1) ATE383854T1 (xx)
AU (1) AU2002342707B2 (xx)
BR (1) BR0212714A (xx)
CA (1) CA2460655C (xx)
DE (2) DE10146275A1 (xx)
EC (1) ECSP045025A (xx)
ES (1) ES2299608T3 (xx)
HK (1) HK1075205A1 (xx)
HU (1) HUP0401485A3 (xx)
IL (2) IL160894A0 (xx)
MX (1) MXPA04002510A (xx)
NO (1) NO333016B1 (xx)
NZ (1) NZ531777A (xx)
PL (1) PL209272B1 (xx)
RU (1) RU2305562C2 (xx)
WO (1) WO2003024444A1 (xx)
ZA (1) ZA200402853B (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10146275A1 (de) 2001-09-18 2003-04-24 Gruenenthal Gmbh Kombination ausgewählter Opioide mit Muscarin-Antagonisten zur Therapie der Harninkontinenz
US7410965B2 (en) 2002-05-29 2008-08-12 Gruenenthal Gmbh Delayed release pharmaceutical composition containing 1-dimethyl-amino-3-(3-methoxyphenyl)-2-methyl-pentan-3-ol
DE10224108A1 (de) * 2002-05-29 2004-01-29 Grünenthal GmbH 1-Dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol enthaltendes Arzneimiitel mit verzögerter Wirkstofffreisetzung
DE10224556A1 (de) * 2002-05-31 2004-01-08 Grünenthal GmbH 1-Dimethylamino- 3-(3-methoxy-phenyl)2-methyl-pentan-3-ol entaltendes Arzneimittel in verschiedenen Formulierungen
EP1480631B1 (en) * 2002-12-20 2007-08-01 Dynogen Pharmaceuticals Inc. Methods of treating non-painful bladder disorders using alpha2-delta- subunit calcium channel modulators
WO2004084879A1 (en) * 2003-03-21 2004-10-07 Dynogen Pharmaceuticals, Inc. Methods for treating lower urinary tract disorders using smooth muscle modulators and alpha-2-delta subunit calcium channel modulators
DE10356362A1 (de) * 2003-11-28 2005-06-23 Grünenthal GmbH Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie von Angststörungen
AU2005245403B2 (en) * 2004-05-14 2012-04-19 Janssen Pharmaceutica N.V. Carboxamido opioid compounds
DE102005009217A1 (de) * 2005-02-25 2006-08-31 Grünenthal GmbH Phosphatsalze der 6-Dimethylaminomethyl-1-(3-methoxyphenyl)-1,3-dihydroxy-cyclohexanverbindungen
US20070032551A1 (en) * 2005-07-22 2007-02-08 Gruenenthal Gmbh Salt of dimethylaminomethyl-phenyl-cyclohexane and crystalline forms thereof
WO2007009794A1 (de) * 2005-07-22 2007-01-25 Grünenthal GmbH Hcl-polymorphe von 3 - ( 2- (dimethylamino) methyl- ( cyclohex-i-yl) ) phenol
US7884247B2 (en) * 2005-07-22 2011-02-08 Gruenenthal Gmbh Salt of dimethylaminomethyl-phenyl-cyclohexane and crystalline forms thereof
DE102007022790A1 (de) 2007-05-11 2008-11-20 Grünenthal GmbH Axomadol zur Schmerzbehandlung bei Arthrose
CA2741984C (en) * 2008-10-30 2018-06-12 Gruenenthal Gmbh Novel and potent tapentadol dosage forms
EP2545027A1 (de) 2010-03-10 2013-01-16 Grünenthal GmbH Kristalline salze und/oder cokristalle von o-desmethyltramadol
BR112012028773A2 (pt) 2010-05-10 2016-07-19 Euro Celtique Sa composições farmacêuticas compreendendo hidromorfona e naloxona
US9993433B2 (en) 2010-05-10 2018-06-12 Euro-Celtique S.A. Manufacturing of active-free granules and tablets comprising the same
JP5840201B2 (ja) 2010-05-10 2016-01-06 ユーロ−セルティーク エス.エイ. 活性剤を負荷した顆粒と追加の活性剤の組合せ
CN103040828B (zh) * 2013-01-07 2015-12-02 常州康普药业有限公司 复方地芬诺酯片及其制备方法
US9814710B2 (en) 2013-11-13 2017-11-14 Euro-Celtique S.A. Hydromorphone and naloxone for treatment of pain and opioid bowel dysfunction syndrome
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB857194A (en) * 1957-07-05 1960-12-29 Clinical Products Ltd Therapeutic agents comprising ion-exchange resins
NL127065C (xx) 1964-04-22
US5736577A (en) 1995-01-31 1998-04-07 Sepracor, Inc. Methods and compositions for treating urinary incontinence using optically pure (S)-oxybutynin
DE3012837A1 (de) * 1979-04-10 1980-10-30 Sandoz Ag Analgetische und myotonolytische praeparate
DE3129982A1 (de) * 1981-07-29 1983-02-17 Jutta 8200 Rosenheim Meyer "antiallergikum"
US5073560A (en) 1990-07-20 1991-12-17 Fisons Corporation Spiro-isoxazolidine derivatives as cholinergic agents
DE4041559A1 (de) 1990-12-22 1992-06-25 Boehringer Ingelheim Kg Neue wirkstoffkombinationen
DE4426245A1 (de) * 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
AU5090796A (en) * 1995-03-03 1996-09-23 Algos Pharmaceutical Corporation Use of dextromethorphan or dextrorphan for the treatment of urinary incontinence
DE19525137C2 (de) 1995-07-11 2003-02-27 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe
DE19609847A1 (de) * 1996-03-13 1997-09-18 Gruenenthal Gmbh Dimethyl-(3-aryl-but-3-enyl)-aminverbindungen als pharmazeutische Wirkstoffe
AU728395B2 (en) 1996-07-19 2001-01-11 Gunnar Aberg S(-)-tolterodine in the treatment of urinary and gastrointestinal disorders
DE69830728T2 (de) * 1997-04-11 2006-05-18 Nippon Shinyaku Co., Ltd. Arzneimittel zur behandlung von häufigem wasserlassen und harninkontinenz
PE20010623A1 (es) 1999-10-05 2001-07-07 Gruenenthal Chemie Uso de (+)-tramadol y/o o-demetiltramadol para tratamiento de urgencia urinaria incrementada y/o incontinencia urinaria
JP2003523382A (ja) * 2000-02-24 2003-08-05 ファルマシア・アンド・アップジョン・カンパニー 新規な薬物の組合せ
DE10059412A1 (de) * 2000-11-30 2002-06-13 Gruenenthal Gmbh Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie der Harninkontinenz
DE10146275A1 (de) 2001-09-18 2003-04-24 Gruenenthal Gmbh Kombination ausgewählter Opioide mit Muscarin-Antagonisten zur Therapie der Harninkontinenz

Also Published As

Publication number Publication date
NO333016B1 (no) 2013-02-18
RU2305562C2 (ru) 2007-09-10
RU2004111788A (ru) 2005-06-10
BR0212714A (pt) 2004-08-03
DE50211566D1 (de) 2008-03-06
EP1429754B1 (de) 2008-01-16
WO2003024444A1 (de) 2003-03-27
HUP0401485A2 (hu) 2004-11-29
CN100384413C (zh) 2008-04-30
JP2005507387A (ja) 2005-03-17
KR100891438B1 (ko) 2009-04-03
KR20040044953A (ko) 2004-05-31
ES2299608T3 (es) 2008-06-01
MXPA04002510A (es) 2004-05-31
CA2460655C (en) 2012-02-07
PL209272B1 (pl) 2011-08-31
CA2460655A1 (en) 2003-03-27
US20040242617A1 (en) 2004-12-02
NZ531777A (en) 2006-11-30
ZA200402853B (en) 2005-02-23
ATE383854T1 (de) 2008-02-15
EP1429754A1 (de) 2004-06-23
IL160894A (en) 2010-04-29
US20120016023A1 (en) 2012-01-19
PL369235A1 (en) 2005-04-18
HUP0401485A3 (en) 2008-04-28
HK1075205A1 (en) 2005-12-09
US8946290B2 (en) 2015-02-03
CN1589140A (zh) 2005-03-02
JP4511176B2 (ja) 2010-07-28
DE10146275A1 (de) 2003-04-24
AU2002342707B2 (en) 2006-10-12
NO20041059L (no) 2004-05-12
ECSP045025A (es) 2004-04-28

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