MXPA03002022A - Conjugados de inhibidor de neuraminidas multivalentes. - Google Patents
Conjugados de inhibidor de neuraminidas multivalentes.Info
- Publication number
- MXPA03002022A MXPA03002022A MXPA03002022A MXPA03002022A MXPA03002022A MX PA03002022 A MXPA03002022 A MX PA03002022A MX PA03002022 A MXPA03002022 A MX PA03002022A MX PA03002022 A MXPA03002022 A MX PA03002022A MX PA03002022 A MXPA03002022 A MX PA03002022A
- Authority
- MX
- Mexico
- Prior art keywords
- neuraminidase
- neuraminidase inhibitor
- inhibitor conjugates
- relates
- compound
- Prior art date
Links
- 229940123424 Neuraminidase inhibitor Drugs 0.000 title 1
- 239000002911 sialidase inhibitor Substances 0.000 title 1
- 102000005348 Neuraminidase Human genes 0.000 abstract 4
- 108010006232 Neuraminidase Proteins 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 125000005647 linker group Chemical group 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000006850 spacer group Chemical group 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- 241000712461 unidentified influenza virus Species 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPR0010A AUPR001000A0 (en) | 2000-09-08 | 2000-09-08 | Novel chemical compounds and their use |
| PCT/AU2001/001128 WO2002020514A1 (en) | 2000-09-08 | 2001-09-07 | Multivalent neuraminidase inhibitor conjugates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA03002022A true MXPA03002022A (es) | 2004-05-04 |
Family
ID=3824061
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA03002022A MXPA03002022A (es) | 2000-09-08 | 2001-09-07 | Conjugados de inhibidor de neuraminidas multivalentes. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7205333B2 (https=) |
| EP (1) | EP1315719A4 (https=) |
| JP (1) | JP5095066B2 (https=) |
| KR (1) | KR20030046406A (https=) |
| AU (3) | AUPR001000A0 (https=) |
| BR (1) | BR0113755A (https=) |
| CA (1) | CA2416336A1 (https=) |
| MX (1) | MXPA03002022A (https=) |
| WO (1) | WO2002020514A1 (https=) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002092555A1 (en) * | 2001-05-11 | 2002-11-21 | Sankyo Company, Limited | Sialic acid derivatives |
| WO2003022841A1 (en) * | 2001-09-07 | 2003-03-20 | Biota Scientific Management Pty Ltd | Intermediates for preparing neuraminidase inhibitor conjugates |
| AUPR879401A0 (en) | 2001-11-09 | 2001-12-06 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
| AUPR879501A0 (en) | 2001-11-09 | 2001-12-06 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
| US7157494B2 (en) * | 2001-11-09 | 2007-01-02 | Biota Scientific Management Pty. Ltd. | Dimeric compounds and their use as anti-viral agents |
| AU2002336823B2 (en) * | 2001-11-09 | 2008-03-20 | Biota Scientific Management Pty Ltd | Dimeric compounds and their use as anti-viral agents |
| AUPR879601A0 (en) * | 2001-11-09 | 2001-12-06 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
| AU2002340632B2 (en) * | 2001-11-09 | 2008-03-20 | Biota Scientific Management Pty Ltd | Dimeric compounds and their use as anti-viral agents |
| AU2002340635B2 (en) * | 2001-11-09 | 2008-03-13 | Biota Scientific Management Pty Ltd | Dimeric compounds and their use as anti-viral agents |
| AUPR879701A0 (en) | 2001-11-09 | 2001-12-06 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
| US7754500B2 (en) * | 2003-11-21 | 2010-07-13 | Anp Technologies, Inc. | Asymmetrically branched polymer conjugates and microarray assays |
| EP1808428B1 (en) | 2006-01-16 | 2010-12-22 | Research Institute of Petroleum Industry (RIPI) | Descaling solutions comprising EDDH |
| US7875747B2 (en) * | 2006-10-10 | 2011-01-25 | Afton Chemical Corporation | Branched succinimide dispersant compounds and methods of making the compounds |
| US7960139B2 (en) | 2007-03-23 | 2011-06-14 | Academia Sinica | Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells |
| EP2192923A2 (en) * | 2007-08-27 | 2010-06-09 | Massachusetts Institute of Technology | Bi-functional polymer-attached inhibitors of influenza virus |
| WO2009148955A2 (en) * | 2008-05-29 | 2009-12-10 | Mdrna, Inc | Multi-arm amines and uses thereof |
| ES2442024T3 (es) | 2008-07-15 | 2014-02-07 | Academia Sinica | Matrices de glucano sobre portaobjetos de vidrio revestidos con aluminio de tipo PTFE y métodos relacionados |
| CN102612514B (zh) * | 2009-07-16 | 2016-01-13 | 格里菲斯大学 | 抗流感剂 |
| US10087236B2 (en) | 2009-12-02 | 2018-10-02 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| US11377485B2 (en) | 2009-12-02 | 2022-07-05 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| US10338069B2 (en) | 2010-04-12 | 2019-07-02 | Academia Sinica | Glycan arrays for high throughput screening of viruses |
| US10130714B2 (en) | 2012-04-14 | 2018-11-20 | Academia Sinica | Enhanced anti-influenza agents conjugated with anti-inflammatory activity |
| WO2014031498A1 (en) | 2012-08-18 | 2014-02-27 | Academia Sinica | Cell-permeable probes for identification and imaging of sialidases |
| EP3013365B1 (en) | 2013-06-26 | 2019-06-05 | Academia Sinica | Rm2 antigens and use thereof |
| EP3013347B1 (en) | 2013-06-27 | 2019-12-11 | Academia Sinica | Glycan conjugates and use thereof |
| JP6486368B2 (ja) | 2013-09-06 | 2019-03-20 | アカデミア シニカＡｃａｄｅｍｉａ Ｓｉｎｉｃａ | 改変されたグリコシル基を含む糖脂質を用いたヒトｉＮＫＴ細胞の活性化 |
| US10150818B2 (en) | 2014-01-16 | 2018-12-11 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
| AU2015206370A1 (en) | 2014-01-16 | 2016-07-07 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
| CN103819665B (zh) * | 2014-02-27 | 2015-10-28 | 中国科学院微生物研究所 | 四价扎那米韦及其制备方法与应用 |
| CN106415244B (zh) | 2014-03-27 | 2020-04-24 | 中央研究院 | 反应性标记化合物及其用途 |
| CA2950415A1 (en) | 2014-05-27 | 2015-12-03 | Academia Sinica | Anti-cd20 glycoantibodies and uses thereof |
| CN106661099A (zh) | 2014-05-27 | 2017-05-10 | 中央研究院 | 抗her2醣抗体及其用途 |
| JP7093612B2 (ja) | 2014-05-27 | 2022-06-30 | アカデミア シニカ | Ｂａｃｔｅｒｏｉｄｅｓ由来のフコシダーゼおよびそれを使用する方法 |
| US10118969B2 (en) | 2014-05-27 | 2018-11-06 | Academia Sinica | Compositions and methods relating to universal glycoforms for enhanced antibody efficacy |
| WO2015184001A1 (en) | 2014-05-28 | 2015-12-03 | Academia Sinica | Anti-tnf-alpha glycoantibodies and uses thereof |
| TWI745275B (zh) | 2014-09-08 | 2021-11-11 | 中央研究院 | 使用醣脂激活人類ｉＮＫＴ細胞 |
| US10495645B2 (en) | 2015-01-16 | 2019-12-03 | Academia Sinica | Cancer markers and methods of use thereof |
| US9975965B2 (en) | 2015-01-16 | 2018-05-22 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
| JP6779887B2 (ja) | 2015-01-24 | 2020-11-04 | アカデミア シニカＡｃａｄｅｍｉａ Ｓｉｎｉｃａ | 新規なグリカンコンジュゲートおよびその使用方法 |
| CN108473483B (zh) | 2015-11-20 | 2022-08-30 | 奥斯维尔医疗私人有限公司 | 用于医药应用的化合物 |
| EP3426693A4 (en) | 2016-03-08 | 2019-11-13 | Academia Sinica | PROCESS FOR MODULAR SYNTHESIS OF N-GLYCANES AND ARRANGEMENTS THEREOF |
| CA3034057A1 (en) | 2016-08-22 | 2018-03-01 | CHO Pharma Inc. | Antibodies, binding fragments, and methods of use |
| TWI861205B (zh) * | 2019-09-06 | 2024-11-11 | 美商席達拉醫療有限公司 | 用於治療病毒感染之組合物及方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AP249A (en) | 1990-04-24 | 1993-03-17 | Biota Scient Management Pty Ltd | Anti-viral compounds. |
| GB9400206D0 (en) | 1994-01-07 | 1994-03-02 | Glaxo Group Ltd | Chemical compound |
| AUPM354694A0 (en) | 1994-01-27 | 1994-02-17 | Biota Scientific Management Pty Ltd | Chemical compounds |
| AUPM623994A0 (en) | 1994-06-15 | 1994-07-07 | Biomolecular Research Institute Limited | Antiviral dendrimers |
| CN100409844C (zh) | 1995-02-27 | 2008-08-13 | 吉里德科学公司 | 神经氨酸苷酶抑制剂 |
| GB9516276D0 (en) | 1995-08-08 | 1995-10-11 | Biota Scient Management | Chemical compounds |
| HU223099B1 (hu) | 1996-03-01 | 2004-03-29 | Biota Scientific Managemant Pty. Ltd. | Eljárás influenzavírus kimutatására és az eljárásban alkalmazható vegyületek |
| US6022888A (en) * | 1996-03-06 | 2000-02-08 | Tsumura & Co. | Iridoid derivatives and neovascularization inhibitors containing the same as active ingredient |
| PT933993E (pt) | 1996-06-14 | 2006-10-31 | Biocryst Pharm Inc | Compostos de ciclopentano substituidos, uteis como inibidores de neuraminidase |
| AUPO104396A0 (en) | 1996-07-17 | 1996-08-08 | Biomolecular Research Institute Limited | Antiviral linear polymers |
| DE69709795T2 (de) | 1996-07-22 | 2002-09-26 | Sankyo Co., Ltd. | Neuraminsäuredervate, ihre Herstellung und medizinische Verwendung |
| HU226130B1 (en) | 1996-08-13 | 2008-05-28 | Daiichi Sankyo Company | Neuraminic acid compounds, medicaments containing the same and method for producing the same medicaments |
| AU732916C (en) * | 1996-11-14 | 2002-06-06 | Biota Scientific Management Pty Ltd | Method and novel compounds for use therein |
| DK1040094T3 (da) | 1997-12-17 | 2009-06-02 | Biocryst Pharm Inc | Substitueret cyklopentan og cyklopenten-forbindelser anvendelige som neuraminidase-inhibitorer |
| AUPP913999A0 (en) | 1999-03-12 | 1999-04-01 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
-
2000
- 2000-09-08 AU AUPR0010A patent/AUPR001000A0/en not_active Abandoned
-
2001
- 2001-09-07 EP EP01964755A patent/EP1315719A4/en not_active Withdrawn
- 2001-09-07 AU AU2001285601A patent/AU2001285601B2/en not_active Ceased
- 2001-09-07 MX MXPA03002022A patent/MXPA03002022A/es active IP Right Grant
- 2001-09-07 AU AU8560101A patent/AU8560101A/xx active Pending
- 2001-09-07 JP JP2002525135A patent/JP5095066B2/ja not_active Expired - Fee Related
- 2001-09-07 WO PCT/AU2001/001128 patent/WO2002020514A1/en not_active Ceased
- 2001-09-07 KR KR10-2003-7001793A patent/KR20030046406A/ko not_active Withdrawn
- 2001-09-07 CA CA002416336A patent/CA2416336A1/en not_active Abandoned
- 2001-09-07 BR BR0113755-7A patent/BR0113755A/pt not_active IP Right Cessation
- 2001-09-07 US US10/363,988 patent/US7205333B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR20030046406A (ko) | 2003-06-12 |
| AUPR001000A0 (en) | 2000-10-05 |
| EP1315719A1 (en) | 2003-06-04 |
| WO2002020514A1 (en) | 2002-03-14 |
| AU8560101A (en) | 2002-03-22 |
| US7205333B2 (en) | 2007-04-17 |
| JP2004507564A (ja) | 2004-03-11 |
| BR0113755A (pt) | 2003-07-08 |
| JP5095066B2 (ja) | 2012-12-12 |
| AU2001285601B2 (en) | 2005-10-27 |
| US20040058853A1 (en) | 2004-03-25 |
| EP1315719A4 (en) | 2005-07-20 |
| CA2416336A1 (en) | 2002-03-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |