BR0113755A - Composto multimérico, processo para a preparação de composto, composição farmacêutica que compreende o composto, processo para o tratamento e/ou profilaxia e detecção de uma infecção por virus, utilização do composto, e inalador que contém a composição - Google Patents
Composto multimérico, processo para a preparação de composto, composição farmacêutica que compreende o composto, processo para o tratamento e/ou profilaxia e detecção de uma infecção por virus, utilização do composto, e inalador que contém a composiçãoInfo
- Publication number
- BR0113755A BR0113755A BR0113755-7A BR0113755A BR0113755A BR 0113755 A BR0113755 A BR 0113755A BR 0113755 A BR0113755 A BR 0113755A BR 0113755 A BR0113755 A BR 0113755A
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- prophylaxis
- multimeric
- virus infection
- neuraminidase
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 11
- 238000000034 method Methods 0.000 title abstract 5
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 238000011321 prophylaxis Methods 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 2
- 238000011282 treatment Methods 0.000 title abstract 2
- 230000009385 viral infection Effects 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 102000005348 Neuraminidase Human genes 0.000 abstract 4
- 108010006232 Neuraminidase Proteins 0.000 abstract 4
- 230000004520 agglutination Effects 0.000 abstract 2
- 230000010460 detection of virus Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 125000005647 linker group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000006850 spacer group Chemical group 0.000 abstract 1
- 241000712461 unidentified influenza virus Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Wood Science & Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPR0010A AUPR001000A0 (en) | 2000-09-08 | 2000-09-08 | Novel chemical compounds and their use |
| PCT/AU2001/001128 WO2002020514A1 (en) | 2000-09-08 | 2001-09-07 | Multivalent neuraminidase inhibitor conjugates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0113755A true BR0113755A (pt) | 2003-07-08 |
Family
ID=3824061
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0113755-7A BR0113755A (pt) | 2000-09-08 | 2001-09-07 | Composto multimérico, processo para a preparação de composto, composição farmacêutica que compreende o composto, processo para o tratamento e/ou profilaxia e detecção de uma infecção por virus, utilização do composto, e inalador que contém a composição |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7205333B2 (https=) |
| EP (1) | EP1315719A4 (https=) |
| JP (1) | JP5095066B2 (https=) |
| KR (1) | KR20030046406A (https=) |
| AU (3) | AUPR001000A0 (https=) |
| BR (1) | BR0113755A (https=) |
| CA (1) | CA2416336A1 (https=) |
| MX (1) | MXPA03002022A (https=) |
| WO (1) | WO2002020514A1 (https=) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002092555A1 (en) * | 2001-05-11 | 2002-11-21 | Sankyo Company, Limited | Sialic acid derivatives |
| EP1423385B1 (en) * | 2001-09-07 | 2008-07-02 | Biota Scientific Management Pty. Ltd. | Intermediates for preparing neuraminidase inhibitor conjugates |
| CN1285591C (zh) | 2001-11-09 | 2006-11-22 | 百奥塔科学管理有限公司 | 二聚化合物及其作为抗病毒剂的应用 |
| AU2002340635B2 (en) * | 2001-11-09 | 2008-03-13 | Biota Scientific Management Pty Ltd | Dimeric compounds and their use as anti-viral agents |
| AU2002336823B2 (en) * | 2001-11-09 | 2008-03-20 | Biota Scientific Management Pty Ltd | Dimeric compounds and their use as anti-viral agents |
| AUPR879601A0 (en) * | 2001-11-09 | 2001-12-06 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
| AUPR879401A0 (en) | 2001-11-09 | 2001-12-06 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
| AUPR879701A0 (en) * | 2001-11-09 | 2001-12-06 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
| AUPR879501A0 (en) | 2001-11-09 | 2001-12-06 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
| AU2002340632B2 (en) * | 2001-11-09 | 2008-03-20 | Biota Scientific Management Pty Ltd | Dimeric compounds and their use as anti-viral agents |
| CN1930304B (zh) * | 2003-11-21 | 2016-01-06 | Anp技术公司 | 不对称支化的聚合物缀合物和微阵列检测 |
| EP1808428B1 (en) | 2006-01-16 | 2010-12-22 | Research Institute of Petroleum Industry (RIPI) | Descaling solutions comprising EDDH |
| US7875747B2 (en) * | 2006-10-10 | 2011-01-25 | Afton Chemical Corporation | Branched succinimide dispersant compounds and methods of making the compounds |
| US7960139B2 (en) | 2007-03-23 | 2011-06-14 | Academia Sinica | Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells |
| WO2009032605A2 (en) * | 2007-08-27 | 2009-03-12 | Massachusetts Institute Of Technology | Bi-functional polymer-attached inhibitors of influenza virus |
| EP2296711A2 (en) * | 2008-05-29 | 2011-03-23 | MDRNA, Inc. | Multi-arm amines and uses thereof |
| JP5986745B2 (ja) | 2008-07-15 | 2016-09-06 | アカデミア シニカＡｃａｄｅｍｉａ Ｓｉｎｉｃａ | Ｐｔｆｅ様のアルミニウム・コート・ガラススライド上のグリカンアレイおよび関連する方法 |
| JP2012532894A (ja) * | 2009-07-16 | 2012-12-20 | グリフィス ユニバーシティ | 抗インフルエンザ薬 |
| US10087236B2 (en) | 2009-12-02 | 2018-10-02 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| US11377485B2 (en) | 2009-12-02 | 2022-07-05 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| US10338069B2 (en) | 2010-04-12 | 2019-07-02 | Academia Sinica | Glycan arrays for high throughput screening of viruses |
| US10130714B2 (en) | 2012-04-14 | 2018-11-20 | Academia Sinica | Enhanced anti-influenza agents conjugated with anti-inflammatory activity |
| WO2014031498A1 (en) | 2012-08-18 | 2014-02-27 | Academia Sinica | Cell-permeable probes for identification and imaging of sialidases |
| EP3013365B1 (en) | 2013-06-26 | 2019-06-05 | Academia Sinica | Rm2 antigens and use thereof |
| WO2014210564A1 (en) | 2013-06-27 | 2014-12-31 | Academia Sinica | Glycan conjugates and use thereof |
| US9782476B2 (en) | 2013-09-06 | 2017-10-10 | Academia Sinica | Human iNKT cell activation using glycolipids with altered glycosyl groups |
| CA2937123A1 (en) | 2014-01-16 | 2015-07-23 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
| US10150818B2 (en) | 2014-01-16 | 2018-12-11 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
| CN103819665B (zh) * | 2014-02-27 | 2015-10-28 | 中国科学院微生物研究所 | 四价扎那米韦及其制备方法与应用 |
| WO2015148915A1 (en) | 2014-03-27 | 2015-10-01 | Academia Sinica | Reactive labelling compounds and uses thereof |
| US10118969B2 (en) | 2014-05-27 | 2018-11-06 | Academia Sinica | Compositions and methods relating to universal glycoforms for enhanced antibody efficacy |
| CA2950423A1 (en) | 2014-05-27 | 2015-12-03 | Academia Sinica | Compositions and methods relating to universal glycoforms for enhanced antibody efficacy |
| KR20170003720A (ko) | 2014-05-27 | 2017-01-09 | 아카데미아 시니카 | 항-ｃｄ20 글리코항체 및 이의 용도 |
| KR102512592B1 (ko) | 2014-05-27 | 2023-03-21 | 아카데미아 시니카 | 항-ｈｅｒ2 글리코항체 및 이의 용도 |
| CN106714829A (zh) | 2014-05-28 | 2017-05-24 | 中央研究院 | 抗TNF‑α醣抗体及其用途 |
| CA2960712A1 (en) | 2014-09-08 | 2016-03-17 | Academia Sinica | Human inkt cell activation using glycolipids |
| US9975965B2 (en) | 2015-01-16 | 2018-05-22 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
| US10495645B2 (en) | 2015-01-16 | 2019-12-03 | Academia Sinica | Cancer markers and methods of use thereof |
| AU2015378564A1 (en) | 2015-01-24 | 2017-07-13 | Academia Sinica | Novel glycan conjugates and methods of use thereof |
| ES2911027T3 (es) * | 2015-11-20 | 2022-05-17 | AusVir Therapeutics Pty Ltd | Compuestos para aplicaciones medicinales |
| WO2017156192A1 (en) | 2016-03-08 | 2017-09-14 | Academia Sinica | Methods for modular synthesis of n-glycans and arrays thereof |
| EP3500594A4 (en) | 2016-08-22 | 2020-03-11 | Cho Pharma Inc. | ANTIBODIES, BINDING FRAGMENTS AND METHOD FOR USE |
| TWI861205B (zh) * | 2019-09-06 | 2024-11-11 | 美商席達拉醫療有限公司 | 用於治療病毒感染之組合物及方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ288492B6 (en) | 1990-04-24 | 2001-06-13 | Biota Scient Management | Derivatives of alpha-D-neuraminic acid, process of their preparation, their use and pharmaceutical preparations based thereon |
| GB9400206D0 (en) | 1994-01-07 | 1994-03-02 | Glaxo Group Ltd | Chemical compound |
| AUPM354694A0 (en) | 1994-01-27 | 1994-02-17 | Biota Scientific Management Pty Ltd | Chemical compounds |
| AUPM623994A0 (en) | 1994-06-15 | 1994-07-07 | Biomolecular Research Institute Limited | Antiviral dendrimers |
| BR9607098B8 (pt) | 1995-02-27 | 2014-11-18 | Gilead Sciences Inc | Composto e composição farmacêutica. |
| GB9516276D0 (en) | 1995-08-08 | 1995-10-11 | Biota Scient Management | Chemical compounds |
| CA2245680C (en) * | 1996-03-01 | 2005-09-27 | Biota Scientific Management Pty. Ltd. | Method of detection of influenza virus and compounds for use therein |
| EP0889041B1 (en) * | 1996-03-06 | 2002-07-24 | TSUMURA & CO. | Novel iridoid derivatives and neovascularization inhibitors containing the same as active ingredient |
| RO121027B1 (ro) | 1996-06-14 | 2006-11-30 | Biocryst Pharmaceuticals, Inc. | Compuşi ciclopentanici substituiţi, compoziţiifarmaceutice şi utilizarea acestora |
| AUPO104396A0 (en) | 1996-07-17 | 1996-08-08 | Biomolecular Research Institute Limited | Antiviral linear polymers |
| ATE211468T1 (de) | 1996-07-22 | 2002-01-15 | Sankyo Co | Neuraminsäuredervate, ihre herstellung und medizinische verwendung |
| CN1126752C (zh) | 1996-08-13 | 2003-11-05 | 三共株式会社 | 神经氨酸化合物 |
| NZ335368A (en) * | 1996-11-14 | 2001-08-31 | Biota Scient Management | Macromolecular compound with one or more neuraminidase binders, binds to the active site of influenza virus neuraminidase |
| CA2315262C (en) | 1997-12-17 | 2009-11-10 | Biocryst Pharmaceuticals, Inc. | Substituted cyclopentane and cyclopentene compounds useful as neuraminidase inhibitors |
| AUPP913999A0 (en) * | 1999-03-12 | 1999-04-01 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
-
2000
- 2000-09-08 AU AUPR0010A patent/AUPR001000A0/en not_active Abandoned
-
2001
- 2001-09-07 AU AU2001285601A patent/AU2001285601B2/en not_active Ceased
- 2001-09-07 US US10/363,988 patent/US7205333B2/en not_active Expired - Fee Related
- 2001-09-07 WO PCT/AU2001/001128 patent/WO2002020514A1/en not_active Ceased
- 2001-09-07 JP JP2002525135A patent/JP5095066B2/ja not_active Expired - Fee Related
- 2001-09-07 AU AU8560101A patent/AU8560101A/xx active Pending
- 2001-09-07 MX MXPA03002022A patent/MXPA03002022A/es active IP Right Grant
- 2001-09-07 BR BR0113755-7A patent/BR0113755A/pt not_active IP Right Cessation
- 2001-09-07 EP EP01964755A patent/EP1315719A4/en not_active Withdrawn
- 2001-09-07 KR KR10-2003-7001793A patent/KR20030046406A/ko not_active Withdrawn
- 2001-09-07 CA CA002416336A patent/CA2416336A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2001285601B2 (en) | 2005-10-27 |
| JP5095066B2 (ja) | 2012-12-12 |
| AUPR001000A0 (en) | 2000-10-05 |
| WO2002020514A1 (en) | 2002-03-14 |
| US7205333B2 (en) | 2007-04-17 |
| EP1315719A1 (en) | 2003-06-04 |
| AU8560101A (en) | 2002-03-22 |
| EP1315719A4 (en) | 2005-07-20 |
| CA2416336A1 (en) | 2002-03-14 |
| JP2004507564A (ja) | 2004-03-11 |
| KR20030046406A (ko) | 2003-06-12 |
| US20040058853A1 (en) | 2004-03-25 |
| MXPA03002022A (es) | 2004-05-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
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