MXPA02009069A - Silenciamiento genetico. - Google Patents
Silenciamiento genetico.Info
- Publication number
- MXPA02009069A MXPA02009069A MXPA02009069A MXPA02009069A MXPA02009069A MX PA02009069 A MXPA02009069 A MX PA02009069A MX PA02009069 A MXPA02009069 A MX PA02009069A MX PA02009069 A MXPA02009069 A MX PA02009069A MX PA02009069 A MXPA02009069 A MX PA02009069A
- Authority
- MX
- Mexico
- Prior art keywords
- animal
- genes
- phenotype
- genetic sequences
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/18—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with another compound as one donor, and incorporation of one atom of oxygen (1.14.18)
- C12Y114/18001—Tyrosinase (1.14.18.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
Landscapes
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invencion se refiere en general a un metodo para inducir, promover o de otro modo facilitar un cambio en el fenotipo de una celula animal o un grupo de celulas animales, incluyendo un animal que comprende dichas celulas. La modulacion de la expresion del fenotipo es convenientemente lograda por medio de la manipulacion genotipica a traves de medios tales como la reduccion de la traduccion del transcrito al producto proteico. La habilidad para inducir, promover o de otro modo facilitar el silenciamiento de las secuencias geneticas expresables proporciona un medio para modular el fenotipo en, por ejemplo, las industrias medica, veterinaria y de la reproduccion animal. Las secuencias geneticas expresables contempladas por la presente invencion incluyen no solamente los genes normalmente residentes en una celula animal particular (los genes indigenas) sino tambien los genes introducidos a traves de medios recombinantes o a traves de la infeccion por agentes patogenos tales como virus.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPQ6363A AUPQ636300A0 (en) | 2000-03-17 | 2000-03-17 | Genetic silencing |
AUPR2700A AUPR270001A0 (en) | 2001-01-24 | 2001-01-24 | Genetic silencing |
PCT/AU2001/000297 WO2001070949A1 (en) | 2000-03-17 | 2001-03-16 | Genetic silencing |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA02009069A true MXPA02009069A (es) | 2004-04-05 |
Family
ID=25646282
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA02009069A MXPA02009069A (es) | 2000-03-17 | 2001-03-16 | Silenciamiento genetico. |
Country Status (12)
Country | Link |
---|---|
US (1) | US20030182672A1 (es) |
EP (1) | EP1272629A4 (es) |
JP (2) | JP2003527856A (es) |
KR (1) | KR20020097198A (es) |
CN (1) | CN1426466A (es) |
AU (1) | AU2001240375A1 (es) |
BR (1) | BR0109269A (es) |
CA (1) | CA2403162A1 (es) |
GB (1) | GB2377221B (es) |
MX (1) | MXPA02009069A (es) |
PL (1) | PL358230A1 (es) |
WO (1) | WO2001070949A1 (es) |
Families Citing this family (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6506559B1 (en) | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
AUPP249298A0 (en) | 1998-03-20 | 1998-04-23 | Ag-Gene Australia Limited | Synthetic genes and genetic constructs comprising same I |
CZ295108B6 (cs) | 1998-03-20 | 2005-05-18 | Benitec Australia Ltd | Syntetický gen obsahující dispergovanou nebo cizorodou deoxyribonukleovou molekulu a genový konstrukt obsahující tento syntetický gen |
EP2314700A1 (en) | 1999-01-28 | 2011-04-27 | Medical College of Georgia Research Institute, Inc | Composition and method for in vivo and in vitro attenuation of gene expression using double stranded RNA |
DE19956568A1 (de) | 1999-01-30 | 2000-08-17 | Roland Kreutzer | Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens |
US6423885B1 (en) | 1999-08-13 | 2002-07-23 | Commonwealth Scientific And Industrial Research Organization (Csiro) | Methods for obtaining modified phenotypes in plant cells |
US7531718B2 (en) | 1999-08-26 | 2009-05-12 | Monsanto Technology, L.L.C. | Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids |
US7067722B2 (en) | 1999-08-26 | 2006-06-27 | Monsanto Technology Llc | Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids |
IL148374A0 (en) | 1999-08-26 | 2002-09-12 | Calgene Llc | Plants with modified polyunsaturated fatty acids |
DE10100586C1 (de) | 2001-01-09 | 2002-04-11 | Ribopharma Ag | Verfahren zur Hemmung der Expression eines Ziegens |
US7829693B2 (en) | 1999-11-24 | 2010-11-09 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting expression of a target gene |
US8273866B2 (en) | 2002-02-20 | 2012-09-25 | Merck Sharp & Dohme Corp. | RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SINA) |
WO2003070918A2 (en) | 2002-02-20 | 2003-08-28 | Ribozyme Pharmaceuticals, Incorporated | Rna interference by modified short interfering nucleic acid |
US8202979B2 (en) | 2002-02-20 | 2012-06-19 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid |
US7423142B2 (en) | 2001-01-09 | 2008-09-09 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting expression of anti-apoptotic genes |
US8546143B2 (en) | 2001-01-09 | 2013-10-01 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting expression of a target gene |
US7767802B2 (en) | 2001-01-09 | 2010-08-03 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting expression of anti-apoptotic genes |
CA2369944A1 (en) | 2001-01-31 | 2002-07-31 | Nucleonics Inc. | Use of post-transcriptional gene silencing for identifying nucleic acid sequences that modulate the function of a cell |
US9994853B2 (en) | 2001-05-18 | 2018-06-12 | Sirna Therapeutics, Inc. | Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference |
US20050148530A1 (en) | 2002-02-20 | 2005-07-07 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA) |
KR20040022449A (ko) | 2001-07-12 | 2004-03-12 | 유니버시티 오브 매사추세츠 | 유전자 불활성화를 매개하는 소형 간섭 rna의 생체내제조 |
JP2005508306A (ja) | 2001-07-23 | 2005-03-31 | ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ | 哺乳類における遺伝子発現のRNAiによる阻害に関する方法および組成物 |
US10590418B2 (en) | 2001-07-23 | 2020-03-17 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for RNAi mediated inhibition of gene expression in mammals |
US20050037989A1 (en) * | 2001-08-27 | 2005-02-17 | Lewis David L. | Inhibition of gene function by delivery of polynucleotide-based gene expression inhibitors to mammalian cells in vivo |
US7745418B2 (en) | 2001-10-12 | 2010-06-29 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting viral replication |
DE10163098B4 (de) | 2001-10-12 | 2005-06-02 | Alnylam Europe Ag | Verfahren zur Hemmung der Replikation von Viren |
DE10202419A1 (de) | 2002-01-22 | 2003-08-07 | Ribopharma Ag | Verfahren zur Hemmung der Expression eines durch eine Chromosomen-Aberration entstandenen Zielgens |
AU2003207708A1 (en) | 2002-02-20 | 2003-09-09 | Sirna Therapeutics, Inc. | Rna interference mediated inhibition of map kinase genes |
US9657294B2 (en) | 2002-02-20 | 2017-05-23 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) |
US9181551B2 (en) | 2002-02-20 | 2015-11-10 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) |
MXPA04009134A (es) | 2002-03-21 | 2005-01-25 | Monsanto Technology Llc | Construcciones de acidos nucleicos y metodos para producir composiciones alteradas de aceite de semilla. |
US7166771B2 (en) | 2002-06-21 | 2007-01-23 | Monsanto Technology Llc | Coordinated decrease and increase of gene expression of more than one gene using transgenic constructs |
US7566813B2 (en) | 2002-03-21 | 2009-07-28 | Monsanto Technology, L.L.C. | Nucleic acid constructs and methods for producing altered seed oil compositions |
US20040172667A1 (en) | 2002-06-26 | 2004-09-02 | Cooper Richard K. | Administration of transposon-based vectors to reproductive organs |
US20050042646A1 (en) | 2002-08-05 | 2005-02-24 | Davidson Beverly L. | RNA interference suppresion of neurodegenerative diseases and methods of use thereof |
US20040241854A1 (en) | 2002-08-05 | 2004-12-02 | Davidson Beverly L. | siRNA-mediated gene silencing |
US20080274989A1 (en) | 2002-08-05 | 2008-11-06 | University Of Iowa Research Foundation | Rna Interference Suppression of Neurodegenerative Diseases and Methods of Use Thereof |
WO2004015062A2 (en) | 2002-08-12 | 2004-02-19 | New England Biolabs, Inc. | Methods and compositions relating to gene silencing |
US7923547B2 (en) | 2002-09-05 | 2011-04-12 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) |
US7122361B2 (en) | 2002-10-10 | 2006-10-17 | Wyeth | Compositions employing a novel human kinase |
WO2004038026A2 (en) | 2002-10-24 | 2004-05-06 | Wyeth | Calcineurin-like human phosphoesterase |
AU2003298689A1 (en) | 2002-11-21 | 2004-06-18 | Wyeth | Methods for diagnosing rcc and other solid tumors |
WO2004050831A2 (en) | 2002-11-27 | 2004-06-17 | Wyeth | Compositions, organisms and methodologies employing a novel human kinase |
WO2005009346A2 (en) * | 2003-06-24 | 2005-02-03 | Mirus Corporation | Inhibition of gene function by delivery of polynucleotide-based gene expression inhibitors to mammalian cells in vivo |
EP1668116A4 (en) | 2003-08-20 | 2007-08-15 | Northern Sydney And Central Co | METHOD FOR IMPROVING EMBRYOVIABILITY |
EP1672064A4 (en) * | 2003-09-22 | 2006-12-20 | Riken | EFFICIENT METHOD FOR GENERATING AN INVERTED REPEAT DNA STRUCTURE |
DE10351149A1 (de) * | 2003-11-03 | 2005-06-30 | Beiersdorf Ag | Oligoribonukleotide zur Behandlung von unerwünschter Pigmentierung der Haut und der Haare durch RNA-Interferenz |
WO2005062881A2 (en) | 2003-12-24 | 2005-07-14 | Transgenrx, Inc. | Gene therapy using transposon-based vectors |
CA2554212A1 (en) | 2004-02-10 | 2005-08-25 | Sirna Therapeutics, Inc. | Rna interference mediated inhibition of gene expression using multifunctional short interfering nucleic acid (multifunctional sina) |
CA2557532A1 (en) | 2004-04-23 | 2005-11-10 | Angela M. Christiano | Inhibition of hairless protein mrna |
US10508277B2 (en) | 2004-05-24 | 2019-12-17 | Sirna Therapeutics, Inc. | Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference |
US7846438B2 (en) | 2004-08-03 | 2010-12-07 | Biogen Idec Ma Inc. | Methods of promoting neurite outgrowth with soluble TAJ polypeptides |
MX2007004310A (es) | 2004-10-13 | 2007-06-18 | Univ Georgia Res Found | Plantas transgenicas resistentes a nematodos. |
CA2610644A1 (en) | 2005-05-31 | 2006-12-07 | Devgen Nv | Rnai for control of insects and arachnids |
EP1931789B1 (en) | 2005-09-20 | 2016-05-04 | BASF Plant Science GmbH | Methods for controlling gene expression using ta-siran |
WO2007043049A1 (en) | 2005-10-11 | 2007-04-19 | Ben-Gurion University Of The Negev Research And Development Authority | Compositions for silencing the expression of vdac1 and uses thereof |
CN103710429B (zh) | 2005-11-29 | 2016-03-30 | 剑桥企业有限公司 | 乳腺癌标志物 |
ES2550099T3 (es) | 2006-01-27 | 2015-11-04 | Biogen Ma Inc. | Antagonistas del receptor Nogo |
CN101421406B (zh) | 2006-02-13 | 2016-08-31 | 孟山都技术有限公司 | 用于产生改变的种子油组成的核酸构建体和方法 |
FR2898908A1 (fr) | 2006-03-24 | 2007-09-28 | Agronomique Inst Nat Rech | Procede de preparation de cellules aviaires differenciees et genes impliques dans le maintien de la pluripotence |
CN102321626B (zh) | 2006-07-21 | 2014-12-10 | 赛伦斯治疗有限公司 | 用于抑制蛋白激酶3表达的方法 |
WO2008097197A1 (en) | 2007-02-05 | 2008-08-14 | National University Of Singapore | Putative cytokinin receptor and methods for use thereof |
BRPI0809130A8 (pt) | 2007-03-21 | 2021-11-03 | Brookhaven Science Ass Llc | Composições combinadas hairpin-antissenso e métodos para modulação da expressão |
PT2279265E (pt) | 2008-04-24 | 2014-12-09 | Newsouth Innovations Pty Ltd | Agrupamento de genes saxitoxina das cianobactérias e deteção de organismos cianotoxicos |
US8093043B2 (en) | 2008-06-04 | 2012-01-10 | New York University | β-TrCP1, β-TrCP2 and RSK1 or RSK2 inhibitors and methods for sensitizing target cells to apoptosis |
WO2010036978A2 (en) | 2008-09-25 | 2010-04-01 | Transgenrx, Inc. | Novel vectors for production of growth hormone |
WO2010036976A2 (en) | 2008-09-25 | 2010-04-01 | Transgenrx, Inc. | Novel vectors for production of antibodies |
UY32145A (es) | 2008-09-29 | 2010-04-30 | Monsanto Technology Llc | Evento transgénico de soja mon87705 y métodos para detectar el mismo |
WO2010072676A1 (en) * | 2008-12-22 | 2010-07-01 | Lek Pharmaceuticals D.D. | Mammalian expression vector |
EP2241627A1 (en) * | 2009-04-17 | 2010-10-20 | LEK Pharmaceuticals d.d. | Mammalian expression vector |
US9150881B2 (en) | 2009-04-09 | 2015-10-06 | Proteovec Holding, L.L.C. | Production of proteins using transposon-based vectors |
ES2644055T3 (es) | 2009-06-05 | 2017-11-27 | Centenary Institute Of Cancer Medicine And Cell Biology | Moléculas terapéuticas y de diagnóstico |
KR101605932B1 (ko) | 2009-12-18 | 2016-03-24 | 노파르티스 아게 | Hsf1-관련 질환을 치료하기 위한 유기 조성물 |
JP2013519869A (ja) | 2010-02-10 | 2013-05-30 | ノバルティス アーゲー | 筋肉成長のための方法および化合物 |
US9260471B2 (en) | 2010-10-29 | 2016-02-16 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using short interfering nucleic acids (siNA) |
BR112014016870A2 (pt) | 2012-01-09 | 2017-06-27 | Huesken Dieter | composições orgânicas para tratar doenças relacionadas com beta-catenina |
BR112017016639A2 (pt) | 2015-02-02 | 2018-06-19 | Meiragtx Uk Ii Ltd | regulação da expressão genética pela modulação mediada de aptâmero de espalhamento alternativo |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5190931A (en) * | 1983-10-20 | 1993-03-02 | The Research Foundation Of State University Of New York | Regulation of gene expression by employing translational inhibition of MRNA utilizing interfering complementary MRNA |
US5272065A (en) * | 1983-10-20 | 1993-12-21 | Research Foundation Of State University Of New York | Regulation of gene expression by employing translational inhibition of MRNA utilizing interfering complementary MRNA |
US5208149A (en) * | 1983-10-20 | 1993-05-04 | The Research Foundation Of State University Of New York | Nucleic acid constructs containing stable stem and loop structures |
US4766072A (en) * | 1985-07-17 | 1988-08-23 | Promega Corporation | Vectors for in vitro production of RNA copies of either strand of a cloned DNA sequence |
US5231020A (en) * | 1989-03-30 | 1993-07-27 | Dna Plant Technology Corporation | Genetic engineering of novel plant phenotypes |
US5034323A (en) * | 1989-03-30 | 1991-07-23 | Dna Plant Technology Corporation | Genetic engineering of novel plant phenotypes |
US5714323A (en) * | 1991-08-30 | 1998-02-03 | The University Of Medecine And Dentistry Of New Jersey | Over expression of single-stranded molecules |
ES2166361T3 (es) * | 1992-02-19 | 2002-04-16 | State Of Oregon Acting By & Th | Produccion de plantas resistentes a los virus a traves de la introduccion de rna viral intraducible de sentido positivo. |
DE4208107A1 (de) * | 1992-03-13 | 1993-09-16 | Bayer Ag | Pseudorabies-virus (prv)-polynukleotide und ihre verwendung zur herstellung von virusresistenten eukaryotischen zellen |
US5624803A (en) * | 1993-10-14 | 1997-04-29 | The Regents Of The University Of California | In vivo oligonucleotide generator, and methods of testing the binding affinity of triplex forming oligonucleotides derived therefrom |
US5578716A (en) * | 1993-12-01 | 1996-11-26 | Mcgill University | DNA methyltransferase antisense oligonucleotides |
US5686649A (en) * | 1994-03-22 | 1997-11-11 | The Rockefeller University | Suppression of plant gene expression using processing-defective RNA constructs |
US6054299A (en) * | 1994-04-29 | 2000-04-25 | Conrad; Charles A. | Stem-loop cloning vector and method |
AU738592C (en) * | 1996-08-02 | 2002-07-25 | Lorus Therapeutics Inc. | Antitumor antisense sequences directed against R1 and R2 components of ribonucleotide reductase |
US5814500A (en) * | 1996-10-31 | 1998-09-29 | The Johns Hopkins University School Of Medicine | Delivery construct for antisense nucleic acids and methods of use |
WO1999032612A1 (en) * | 1997-12-20 | 1999-07-01 | Genencor International, Inc. | Fluidized bed matrix granule |
US6506559B1 (en) * | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
AUPP249298A0 (en) * | 1998-03-20 | 1998-04-23 | Ag-Gene Australia Limited | Synthetic genes and genetic constructs comprising same I |
CZ295108B6 (cs) * | 1998-03-20 | 2005-05-18 | Benitec Australia Ltd | Syntetický gen obsahující dispergovanou nebo cizorodou deoxyribonukleovou molekulu a genový konstrukt obsahující tento syntetický gen |
ATE507299T1 (de) * | 1998-04-08 | 2011-05-15 | Commw Scient Ind Res Org | Verfahren und mittel zum erhalt von veränderten phänotypen |
EP2314700A1 (en) * | 1999-01-28 | 2011-04-27 | Medical College of Georgia Research Institute, Inc | Composition and method for in vivo and in vitro attenuation of gene expression using double stranded RNA |
US6423885B1 (en) * | 1999-08-13 | 2002-07-23 | Commonwealth Scientific And Industrial Research Organization (Csiro) | Methods for obtaining modified phenotypes in plant cells |
GB9927444D0 (en) * | 1999-11-19 | 2000-01-19 | Cancer Res Campaign Tech | Inhibiting gene expression |
ES2336887T5 (es) * | 2000-03-30 | 2019-03-06 | Whitehead Inst Biomedical Res | Mediadores de interferencia por ARN específicos de secuencias de ARN |
BR0111839A (pt) * | 2000-06-23 | 2003-09-16 | Du Pont | Construções recombinantes, método para a redução da expressão de um mrna alvo ou qualquer mrna endógeno substancialmente similar, rna e método para a identificação ou seleção de um gene vegetal essencial |
US7109393B2 (en) * | 2000-08-15 | 2006-09-19 | Mendel Biotechnology, Inc. | Methods of gene silencing using inverted repeat sequences |
-
2001
- 2001-03-16 WO PCT/AU2001/000297 patent/WO2001070949A1/en not_active Application Discontinuation
- 2001-03-16 PL PL01358230A patent/PL358230A1/xx not_active Application Discontinuation
- 2001-03-16 JP JP2001569332A patent/JP2003527856A/ja active Pending
- 2001-03-16 AU AU2001240375A patent/AU2001240375A1/en not_active Abandoned
- 2001-03-16 KR KR1020027012237A patent/KR20020097198A/ko not_active Application Discontinuation
- 2001-03-16 BR BR0109269-3A patent/BR0109269A/pt not_active Application Discontinuation
- 2001-03-16 CA CA002403162A patent/CA2403162A1/en not_active Abandoned
- 2001-03-16 EP EP01911291A patent/EP1272629A4/en not_active Withdrawn
- 2001-03-16 MX MXPA02009069A patent/MXPA02009069A/es unknown
- 2001-03-16 CN CN01808640A patent/CN1426466A/zh active Pending
- 2001-03-16 GB GB0224195A patent/GB2377221B/en not_active Expired - Lifetime
-
2002
- 2002-09-16 US US10/245,805 patent/US20030182672A1/en not_active Abandoned
-
2011
- 2011-08-19 JP JP2011179375A patent/JP2011229542A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2001240375A1 (en) | 2001-10-03 |
CA2403162A1 (en) | 2001-09-27 |
US20030182672A1 (en) | 2003-09-25 |
EP1272629A4 (en) | 2004-12-22 |
CN1426466A (zh) | 2003-06-25 |
JP2011229542A (ja) | 2011-11-17 |
GB0224195D0 (en) | 2002-11-27 |
EP1272629A1 (en) | 2003-01-08 |
GB2377221B (en) | 2004-08-18 |
BR0109269A (pt) | 2002-12-17 |
WO2001070949A1 (en) | 2001-09-27 |
JP2003527856A (ja) | 2003-09-24 |
PL358230A1 (en) | 2004-08-09 |
GB2377221A (en) | 2003-01-08 |
KR20020097198A (ko) | 2002-12-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB2377221A (en) | Genetic silencing | |
Yount et al. | Rewiring the severe acute respiratory syndrome coronavirus (SARS-CoV) transcription circuit: engineering a recombination-resistant genome | |
DE69637660D1 (de) | Verfahren zür einführung und expression von genen in tierischen zellen | |
AUPN477695A0 (en) | Gene therapy | |
GR3029913T3 (en) | Treatment of cell populations. | |
AP1678A (en) | Novel modified nucleic acid sequences and methods for increasing mRNA levels and protein expression in cell systems. | |
NO973685L (no) | Multi-tumor avvikende vekstgener | |
DK0941318T3 (da) | Håndvægtformede konstruerede ekspressionssystemer til genterapi | |
SG149003A1 (en) | Gene expression technique | |
WO2001090331A3 (en) | C1 bacteriophage lytic system | |
HK1047129B (zh) | 真核細胞的序列特異性dna重組 | |
ATE239036T1 (de) | Rekombinantes core-streptavidin | |
ES2103819T3 (es) | Metodo para el diagnostico del virus del papiloma humano tipo 16 utilizando la reaccion en cadena de la polimerasa. | |
ES2193144T3 (es) | Compuestos de dna que comprenden secuencias que codifican manuronano c-5-epimerasa. | |
MX9202512A (es) | Virus de avipox recombinante, cultivo de celulas infectadas por este virusy vacunas para las aves de corral derivadas de este virus. | |
CA2361892A1 (en) | Treatment of tumors with genetically engineered herpes virus | |
ATE228016T1 (de) | Lebendvakzine zur behandlung von tumorerkrankungen | |
El-Mohamady et al. | Concurrent detection of bovine viral diarrhoea virus and bovine herpesvirus-1 in bulls’ semen and their effect on semen quality | |
AU8491401A (en) | Phage-dependent superproduction of biologically active protein and peptides | |
Reanney | A regulatory role for viral RNA in eukaryotes | |
HUP0102861A2 (hu) | Attenuált lóherpeszvírus | |
ATE278786T1 (de) | Genetische kaskaderegulierte expression von klonierten genen | |
DE69533626D1 (de) | Tioredioxine h aus zwig und hart-weizen und ähnliche proteine, diese kodierende dna-fragmente und verfahren zu ihrer herstellung | |
Mondal et al. | Advances in animal genomics | |
NZ511168A (en) | Recombinant CELO virus and CELO virus DNA |