MXPA02001473A - Azaindoles que tienen afinidad con el receptor de serotonina. - Google Patents

Azaindoles que tienen afinidad con el receptor de serotonina.

Info

Publication number
MXPA02001473A
MXPA02001473A MXPA02001473A MXPA02001473A MXPA02001473A MX PA02001473 A MXPA02001473 A MX PA02001473A MX PA02001473 A MXPA02001473 A MX PA02001473A MX PA02001473 A MXPA02001473 A MX PA02001473A MX PA02001473 A MXPA02001473 A MX PA02001473A
Authority
MX
Mexico
Prior art keywords
group
formula
azaindoles
double bond
serotonin receptor
Prior art date
Application number
MXPA02001473A
Other languages
English (en)
Spanish (es)
Inventor
Tao Xin
Original Assignee
Nps Allelix Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nps Allelix Corp filed Critical Nps Allelix Corp
Publication of MXPA02001473A publication Critical patent/MXPA02001473A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
MXPA02001473A 1999-08-12 2000-08-14 Azaindoles que tienen afinidad con el receptor de serotonina. MXPA02001473A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14834399P 1999-08-12 1999-08-12
PCT/IB2000/001122 WO2001012629A1 (en) 1999-08-12 2000-08-14 Azaindoles having serotonin receptor affinity

Publications (1)

Publication Number Publication Date
MXPA02001473A true MXPA02001473A (es) 2003-07-21

Family

ID=22525363

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02001473A MXPA02001473A (es) 1999-08-12 2000-08-14 Azaindoles que tienen afinidad con el receptor de serotonina.

Country Status (10)

Country Link
EP (1) EP1204662B1 (enExample)
JP (1) JP4969004B2 (enExample)
AT (1) ATE268330T1 (enExample)
AU (1) AU779832B2 (enExample)
CA (1) CA2382247C (enExample)
DE (1) DE60011269T2 (enExample)
DK (1) DK1204662T3 (enExample)
ES (1) ES2222219T3 (enExample)
MX (1) MXPA02001473A (enExample)
WO (1) WO2001012629A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10030037A1 (de) 2000-06-17 2001-12-20 Mann & Hummel Filter Zylindrische Filterpatrone mit Stützrohr
ITRM20010356A1 (it) * 2001-06-21 2002-12-23 Sigma Tau Ind Farmaceuti "5-alogeno derivati della triptamina utili come ligandi del recettore5-ht6 e/o 5-ht7 della serotonina.
HUP0402640A3 (en) * 2001-12-20 2012-09-28 Wyeth Corp Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands, process for their preparation and pharmaceutical compositions thereof
TW200301251A (en) * 2001-12-20 2003-07-01 Wyeth Corp Azaindolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands
GB0202679D0 (en) * 2002-02-05 2002-03-20 Glaxo Group Ltd Novel compounds
ATE346068T1 (de) * 2002-03-27 2006-12-15 Glaxo Group Ltd Chinolin- und aza-indolderivate und deren verwendung als 5-ht6 liganden
UA78999C2 (en) * 2002-06-04 2007-05-10 Wyeth Corp 1-(aminoalkyl)-3-sulfonylazaindoles as ligands of 5-hydroxytryptamine-6
EP1897876A3 (en) 2002-06-20 2009-03-18 Biovitrum AB (publ) Compounds useful for the treatment of obesity, type II diabetes and CNS disorders
TW200403243A (en) 2002-07-18 2004-03-01 Wyeth Corp 1-Heterocyclylalkyl-3-sulfonylazaindole or-azaindazole derivatives as 5-hydroxytryptamine-6 ligands
EP1592772A2 (en) * 2003-01-31 2005-11-09 Pfizer Products Incorporated 5ht7 antagonists and inverse agonists
CN100482662C (zh) * 2003-02-14 2009-04-29 惠氏公司 作为5-羟基色胺-6配体的杂环基-3-磺酰基氮杂吲哚或-氮杂吲唑衍生物
JP2006528186A (ja) * 2003-07-23 2006-12-14 ワイス ５−ヒドロキシトリプタミン−６リガンドとしてのスルホニルジヒドロベンゾイミダゾロン化合物
ES2222828B1 (es) * 2003-07-30 2006-04-16 Laboratorios Del Dr. Esteve, S.A. Derivados de 1-sulfonilindoles, su preparacion y su aplicacion como medicamentos.
AU2007217040A1 (en) * 2006-02-17 2007-08-30 Memory Pharmaceuticals Corporation Compounds having 5-HT6 receptor affinity
EP2046741B1 (en) * 2006-07-03 2012-10-31 Proximagen Ltd. Indoles as 5-ht6 modulators
WO2012160464A1 (en) * 2011-05-26 2012-11-29 Daiichi Sankyo Company, Limited Heterocyclic compounds as protein kinase inhibitors
EP3083588B1 (en) 2013-12-20 2020-12-09 Sunshine Lake Pharma Co., Ltd. Aromatic heterocyclic compounds and their application in pharmaceuticals
EP3166924B1 (en) 2014-07-08 2019-02-20 Sunshine Lake Pharma Co., Ltd. Aromatic heterocyclic derivatives and pharmaceutical applications thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9406128A (pt) * 1993-03-01 1996-02-27 Merck Sharp & Dohme Uso de um composto processo para o tratamento e/ou prevençao de distúrbios psicóticos composto composiçao farmacêutica processos para a preparaçao de um composto e de uma composiçao farmacêutica
US5846982A (en) * 1996-06-14 1998-12-08 Eli Lilly And Company Inhibition of serotonin reuptake
EP0875513A1 (en) * 1997-04-14 1998-11-04 Eli Lilly And Company Substituted heteroaromatic 5-HT 1F agonists
US5905084A (en) * 1997-11-14 1999-05-18 Eli Lilly And Company 5-HTIF -agonists effective in treating migraine
US6562809B1 (en) * 1998-09-18 2003-05-13 Nps Allelix Corp. 3-bicycloindole compounds

Also Published As

Publication number Publication date
JP4969004B2 (ja) 2012-07-04
JP2003507380A (ja) 2003-02-25
DE60011269T2 (de) 2005-06-23
ES2222219T3 (es) 2005-02-01
WO2001012629A1 (en) 2001-02-22
DE60011269D1 (de) 2004-07-08
DK1204662T3 (da) 2004-10-04
CA2382247A1 (en) 2001-02-22
EP1204662B1 (en) 2004-06-02
AU6310300A (en) 2001-03-13
CA2382247C (en) 2010-09-28
EP1204662A1 (en) 2002-05-15
AU779832B2 (en) 2005-02-10
ATE268330T1 (de) 2004-06-15

Similar Documents

Publication Publication Date Title
MXPA02001473A (es) Azaindoles que tienen afinidad con el receptor de serotonina.
IL110091A (en) POLYSUBSTITUTED IMIDAZO £4, 5-c| PYRIDIN-4-AMINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
TW370450B (en) Substituted 1H-3-aryl-pyrrolidine-2,4-dione derivatives
BR0315405A (pt) Compostos inibidores da integrase tricìclica pré-organizados
HU9203016D0 (en) New taxane compounds substituted with alkoxy and pharmaceutical preparatives containing these compounds
HU9203017D0 (en) New taxane compounds substituted with furyl or thienyl and pharmaceutical preparatives containing these compounds
CO4700455A1 (es) Derivados tetraciclicos y proceso para su preparacion
DK0733621T3 (da) Hidtil ukendte imidazolderivater og fremgangsmåde til fremstilling af disse
BG104287A (en) Halogensubstituted tetracyclic derivatives of tetrahydrofuran
NZ214787A (en) Arylcyclobutylalkylamines and pharmaceutical compositions
TW200612920A (en) Novel imidazolidine derivatives
DK1026167T3 (da) Tricykliske triazolobenzazepinderivater, fremgangsmåde til fremstilling af disse samt antiallergiske midler
IL103019A0 (en) Dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
BR9710614A (pt) Esteres arilcicloalcanos carboxìlicos, seu uso, composição farmacêutica e preparação.
CA2316388A1 (en) Tetrahydrobenzindole derivative
YU43902A (sh) Novi razgranati supstituisani amino derivati od 3-amino-1- -fenil-1h(1,2,4) triazola, postupak za njihovo dobijanje i farmaceutski preparati koji ih sadrže
MXPA04001171A (es) Compuestos policiclicos condensados.
UA66748C2 (en) Phenyl substituted 4-azasteroids fluroderivatives, methods for the preparation thereof (variants) and pharmaceutical composition based thereon
DK1163258T3 (da) Derivater af 22R-hydroxycholesta-8, 14-dien til inhiberingen af meiosis
ES2158768A1 (es) Derivados de oxopiperazinilo y composiciones estabilizadas a la luz.
IL106564A (en) Tetrahydronaphthalene derivatives their preparation and pharmaceutical compositions containing them
GB0114699D0 (en) Organic compounds
ES543783A0 (es) Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol
DE69528984D1 (de) Hemmung der leukotrienbiosynthese mittels harnstoffderivaten
TW349935B (en) Oxime ether compounds, their intermediates and their use as pesticides

Legal Events

Date Code Title Description
FG Grant or registration
GB Transfer or rights
HC Change of company name or juridical status