MX9708854A - Terapia de genes para regulacion de celulas efectoras. - Google Patents
Terapia de genes para regulacion de celulas efectoras.Info
- Publication number
- MX9708854A MX9708854A MX9708854A MX9708854A MX9708854A MX 9708854 A MX9708854 A MX 9708854A MX 9708854 A MX9708854 A MX 9708854A MX 9708854 A MX9708854 A MX 9708854A MX 9708854 A MX9708854 A MX 9708854A
- Authority
- MX
- Mexico
- Prior art keywords
- nucleic acid
- encoding nucleic
- present
- acid molecules
- gene therapy
- Prior art date
Links
- 239000012636 effector Substances 0.000 title abstract 2
- 230000009134 cell regulation Effects 0.000 title 1
- 238000001415 gene therapy Methods 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 7
- 102000039446 nucleic acids Human genes 0.000 abstract 7
- 108020004707 nucleic acids Proteins 0.000 abstract 7
- 239000000203 mixture Substances 0.000 abstract 3
- 239000002671 adjuvant Substances 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 2
- 108700001237 Nucleic Acid-Based Vaccines Proteins 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 210000002540 macrophage Anatomy 0.000 abstract 1
- 210000001616 monocyte Anatomy 0.000 abstract 1
- 210000000822 natural killer cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Plant Pathology (AREA)
- Mycology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Virology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/446,918 US5705151A (en) | 1995-05-18 | 1995-05-18 | Gene therapy for T cell regulation |
| US08/580,806 US5935568A (en) | 1995-05-18 | 1995-12-29 | Gene therapy for effector cell regulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9708854A true MX9708854A (es) | 1998-08-30 |
Family
ID=27034800
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9708854A MX9708854A (es) | 1995-05-18 | 1997-11-17 | Terapia de genes para regulacion de celulas efectoras. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5935568A (2) |
| EP (1) | EP0850071A4 (2) |
| JP (1) | JPH11508762A (2) |
| KR (1) | KR19990014875A (2) |
| AU (1) | AU704012B2 (2) |
| CA (1) | CA2221305A1 (2) |
| MX (1) | MX9708854A (2) |
| WO (1) | WO1996036366A1 (2) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6075119A (en) * | 1997-04-07 | 2000-06-13 | The Rockefeller University | Peptides useful for reducing symptoms of toxic shock syndrome |
| US6713284B2 (en) | 1997-06-25 | 2004-03-30 | The United States Of America As Represented By The Secretary Of The Army | Bacterial superantigen vaccines |
| US6977074B2 (en) | 1997-07-10 | 2005-12-20 | Mannkind Corporation | Method of inducing a CTL response |
| DE69837706T2 (de) * | 1997-07-21 | 2008-01-10 | Active Biotech Ab | Zytolyse der geeigneten zielzellen mit superantigen konjugate mittels der induktion von t-zell aktivierung |
| US7795020B2 (en) | 1998-01-14 | 2010-09-14 | Morphogenesis, Inc. | Tumor cell vaccines |
| US7348015B2 (en) | 1998-01-14 | 2008-03-25 | Morphogenesis, Inc. | Antigen modified cancer cell vaccines for cancer therapy |
| WO1999036433A2 (en) * | 1998-01-14 | 1999-07-22 | Morphogenesis, Inc. | Materials and methods for treating oncological disease |
| NZ505877A (en) * | 1998-01-16 | 2002-10-25 | Univ Johns Hopkins | Oral delivery of nucleic acid vaccines by particulate complexes |
| IL138075A0 (en) * | 1998-02-27 | 2001-10-31 | Univ Pennsylvania | Vaccines, immunotherapeutics and methods for using the same |
| AU765260B2 (en) * | 1998-04-20 | 2003-09-11 | Torrey Pines Institute For Molecular Studies | Topical immunostimulation to induce langerhans cell migration |
| DE69929432T2 (de) * | 1998-04-22 | 2006-09-28 | Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville | Erhöhung der immunantworten bei genetischer immunisierung durch verwendung eines chemokins |
| US6919318B1 (en) | 1998-04-22 | 2005-07-19 | Chiron Corporation | Enhancing immune responses to genetic immunization by using a chemokine |
| CA2333750A1 (en) * | 1998-06-23 | 1999-12-29 | Dale T. Umetsu | Adjuvant therapy |
| US20040247662A1 (en) * | 1998-06-25 | 2004-12-09 | Dow Steven W. | Systemic immune activation method using nucleic acid-lipid complexes |
| US20030022854A1 (en) * | 1998-06-25 | 2003-01-30 | Dow Steven W. | Vaccines using nucleic acid-lipid complexes |
| DE69940157D1 (en) * | 1998-07-10 | 2009-02-05 | U S Medical Res Inst Of Infect | Anthrax-impfstoff |
| CA2338184A1 (en) * | 1998-08-13 | 2000-02-24 | Walter Reed Army Institute Of Research | Bacterial superantigen vaccines |
| CA2345023A1 (en) * | 1998-10-07 | 2000-04-13 | The Rockefeller University | Peptides useful for reducing symptoms of toxic shock syndrome and septic shock |
| US6562800B1 (en) * | 1998-10-30 | 2003-05-13 | University Of Southern California | Use of immunopotentiating sequences for inducing immune response |
| EP1185627A2 (en) * | 1999-06-01 | 2002-03-13 | Cornell Research Foundation, Inc. | Activation of dendritic cells to enhance immunity |
| US7361329B2 (en) * | 2000-04-21 | 2008-04-22 | Chemocentryx, Inc. | Compositions for inducing an immune response |
| US7205278B2 (en) | 2001-06-14 | 2007-04-17 | The Scripps Research Institute | Stabilized proteins with engineered disulfide bonds |
| SE0102327D0 (sv) | 2001-06-28 | 2001-06-28 | Active Biotech Ab | A novel engineered superantigen for human therapy |
| WO2003035106A1 (en) * | 2001-10-24 | 2003-05-01 | Chemocentryx | Methods and compositions for inducing an immune response by co-administering a chemokine with an antigen |
| WO2004044155A2 (en) * | 2002-11-07 | 2004-05-27 | Beth Israel Deaconess Medical Center | MIP-1α AND GM-CSF AS ADJUVANTS OF IMMUNE RESPONSE |
| WO2005023853A1 (ja) | 2003-09-05 | 2005-03-17 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | プロテアーゼ耐性seb改変体およびそれを含むワクチン |
| US9375468B2 (en) * | 2012-02-08 | 2016-06-28 | Premune Ab | Prevention of inflammatory disorders in domestic non-human mammals |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5145676A (en) * | 1981-09-08 | 1992-09-08 | The Rockefeller University | Method and agents for promoting wound healing |
| US4994369A (en) * | 1987-12-15 | 1991-02-19 | The Board Of Trustees Of The Leland Stanford Jr. Univ. | T-cell activation related gene |
| US5703055A (en) * | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| IL95742A (en) * | 1989-09-19 | 2000-12-06 | Innogenetics Nv | Recombinant polypeptides and peptides nucleic acids coding for the same and use of these polypeptides and peptides in the diagnosis of tuberculosis |
| SE8903100D0 (sv) * | 1989-09-20 | 1989-09-20 | Pharmacia Ab | New pharmaceutical agent |
| CA2078003C (en) * | 1990-01-17 | 2006-11-21 | David S. Terman | Tumor killing effects of enterotoxins and related compounds |
| WO1993024136A1 (en) * | 1991-01-17 | 1993-12-09 | Terman David S | Tumor killing effects of enterotoxins, superantigens, and related compounds |
| EP0499003A1 (en) * | 1991-02-14 | 1992-08-19 | N.V. Innogenetics S.A. | Polypeptides and peptides, particularly recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnosis of tuberculosis |
| US5858784A (en) * | 1991-12-17 | 1999-01-12 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol- and liposome-based delivery |
| WO1994004196A1 (en) * | 1992-08-14 | 1994-03-03 | Imperial Cancer Research Technology Limited | Tumour therapy |
| US5593972A (en) * | 1993-01-26 | 1997-01-14 | The Wistar Institute | Genetic immunization |
| WO1995000178A1 (en) * | 1993-06-25 | 1995-01-05 | Board Of Regents, The University Of Texas System | Pore-forming and superantigen encoding toxin cassettes for gene therapy |
-
1995
- 1995-12-29 US US08/580,806 patent/US5935568A/en not_active Expired - Fee Related
-
1996
- 1996-05-20 CA CA002221305A patent/CA2221305A1/en not_active Abandoned
- 1996-05-20 AU AU58016/96A patent/AU704012B2/en not_active Ceased
- 1996-05-20 EP EP96914743A patent/EP0850071A4/en not_active Withdrawn
- 1996-05-20 JP JP8535139A patent/JPH11508762A/ja not_active Ceased
- 1996-05-20 WO PCT/US1996/007432 patent/WO1996036366A1/en not_active Ceased
- 1996-05-20 KR KR1019970708220A patent/KR19990014875A/ko not_active Withdrawn
-
1997
- 1997-11-17 MX MX9708854A patent/MX9708854A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0850071A1 (en) | 1998-07-01 |
| JPH11508762A (ja) | 1999-08-03 |
| KR19990014875A (ko) | 1999-02-25 |
| AU704012B2 (en) | 1999-04-01 |
| US5935568A (en) | 1999-08-10 |
| CA2221305A1 (en) | 1996-11-21 |
| AU5801696A (en) | 1996-11-29 |
| EP0850071A4 (en) | 2005-05-25 |
| WO1996036366A1 (en) | 1996-11-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX9708854A (es) | Terapia de genes para regulacion de celulas efectoras. | |
| CA2223433A1 (en) | Ob protein compositions and methods | |
| CY1119951T1 (el) | Συνθεσεις για αυξηση δραστηριοτητας τελομερασης και αγωγη λοιμωξης hiv | |
| IL160015A0 (en) | Use of biologically active hiv-1 tat, fragments or derivatives thereof, to target and/or to activate antigen-presenting cells, and/or to deliver cargo molecules for preventive or therapeutic vaccination and/or to treat other diseases | |
| DE69731540D1 (de) | Behandlung von diarrhoe | |
| ATE323169T1 (de) | Plasmid zur verabreichung von nukleine säuren und verwendungsverfahren | |
| DE69635899D1 (de) | Polypeptid, das die differenzierung unterdrueckt | |
| WO1999046366A8 (en) | Uses for humane non-autologous mesenchymal stem cells | |
| NZ504026A (en) | Methods for treating hypercoagulable states or acquired protein C deficiency using human-activated protein C | |
| AU6989094A (en) | Compositions and methods for treating cancer and hyperproliferative disorders | |
| NZ332720A (en) | Therapeutic uses of bactericidal/permeability increasing (BPI) protein to treat human meningococcemia | |
| EP0400958A3 (en) | Live vaccines | |
| NO931141L (no) | Tnf-muteiner | |
| NO960309L (no) | Agonister og antagonister for humaninterleukin-10 | |
| Schluesener et al. | Transient in vivo activation of rat brain macrophages/microglial cells and astrocytes by immunostimulatory multiple CpG oligonucleotides | |
| BR0010155A (pt) | Proteìnas isolada, e quimérica, composição, molécula de ácido nucleico, plasmìdeo, vacina recombinante ou vacina atenuada, composição de vacina recombinante ou composição de vacina atenuada, composição farmacêutica, métodos de imunizar um indivìduo contra um imunógeno, proteìna não-cd80 isolada, molécula de ácido nucleico, e, método de imunossuprimir um indivìduo | |
| CA2272407A1 (en) | Method and compositions for stimulation of an immune response to a differentiation antigen stimulated by an altered differentiation antigen | |
| DE69635349D1 (de) | Nukleotidsequenzen, proteine, medikamente und diagnoseagentien zur anwendung in krebsbehandlung | |
| IL123642A (en) | Pharmaceutical compositions comprising mononuclear phagocytes to promote axonal regeneration | |
| DE69833876D1 (de) | Zusammensetzungen und methoden zur zielgerichteten abgabe von biologisch aktivenfaktoren | |
| NZ504445A (en) | Nucleic acid sequences of genes of the high mobility group proteins and their use in treating tumours, vascular disorders and as a contraceptive | |
| WO2000045849A3 (en) | Use of cationic lipids to generate anti-tumor immunity | |
| EA200700656A1 (ru) | Стабильные жидкие композиции плазмидной днк | |
| ATE310828T1 (de) | Implantat und vektor zur behandlung von erworbenen krankheiten | |
| BR0317132A (pt) | Métodos de diagnóstico e tratamento de doença pulmonar intersticial |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |